| | gene | name | fitness | t score | description | |
|---|
| b3960 | argH | -5.0 | -19.3 | argininosuccinate lyase (NCBI) | compare |
| b3172 | argG | -4.9 | -15.6 | argininosuccinate synthase (NCBI) | compare |
| b0523 | purE | -4.8 | -7.1 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2838 | lysA | -4.4 | -15.6 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0003 | thrB | -4.4 | -8.8 | homoserine kinase (NCBI) | compare |
| b1281 | pyrF | -4.3 | -3.0 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2557 | purL | -4.3 | -17.3 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0907 | serC | -4.2 | -9.5 | phosphoserine aminotransferase (NCBI) | compare |
| b0522 | purK | -4.1 | -13.9 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2476 | purC | -4.1 | -6.2 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0004 | thrC | -4.0 | -13.5 | threonine synthase (NCBI) | compare |
| b2312 | purF | -3.9 | -8.9 | amidophosphoribosyltransferase (NCBI) | compare |
| b0908 | aroA | -3.8 | -13.4 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b4388 | serB | -3.7 | -8.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b4005 | purD | -3.7 | -12.1 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b4006 | purH | -3.7 | -14.8 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2913 | serA | -3.5 | -12.6 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b1062 | pyrC | -3.4 | -5.6 | dihydroorotase (NCBI) | compare |
| b3642 | pyrE | -3.1 | -2.2 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0222 | lpcA | -3.1 | -2.1 | phosphoheptose isomerase (NCBI) | compare |
| b0002 | thrA | -3.1 | -14.6 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b3870 | glnA | -3.0 | -3.5 | glutamine synthetase (NCBI) | compare |
| b0145 | dksA | -2.9 | -3.9 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b2501 | ppk | -2.9 | -11.9 | polyphosphate kinase (NCBI) | compare |
| b1260 | trpA | -2.9 | -8.7 | tryptophan synthase subunit alpha (NCBI) | compare |
| b2499 | purM | -2.8 | -7.2 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b0049 | apaH | -2.8 | -1.9 | diadenosinetetraphosphatase (NCBI) | compare |
| b3956 | ppc | -2.8 | -19.1 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b1261 | trpB | -2.7 | -5.1 | tryptophan synthase subunit beta (NCBI) | compare |
| b1882 | cheY | -2.7 | -1.1 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b2564 | pdxJ | -2.7 | -7.9 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b2329 | aroC | -2.7 | -8.9 | chorismate synthase (NCBI) | compare |
| b0386 | proC | -2.7 | -3.6 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2318 | truA | -2.6 | -4.0 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2188 | yejM | -2.5 | -13.7 | predicted hydrolase, inner membrane (NCBI) | compare |
| b2808 | gcvA | -2.5 | -5.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3389 | aroB | -2.5 | -12.6 | 3-dehydroquinate synthase (NCBI) | compare |
| b3281 | aroE | -2.4 | -15.4 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0945 | pyrD | -2.4 | -4.3 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0564 | appY | -2.4 | -1.1 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0032 | carA | -2.4 | -4.2 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b4214 | cysQ | -2.3 | -15.1 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b3052 | rfaE | -2.3 | -3.1 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b4245 | pyrB | -2.3 | -3.1 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b4702 | mgtL | -2.2 | -1.5 | regulatory leader peptide for mgtA (NCBI) | compare |
| b2762 | cysH | -2.2 | -12.1 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3790 | rffC | -2.1 | -4.5 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b0052 | pdxA | -2.1 | -12.8 | 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) | compare |
| b2912 | ygfA | -2.1 | -2.8 | putative ligase (VIMSS) | compare |
| b1830 | prc | -2.1 | -4.7 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b4481 | rffT | -2.0 | -5.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b2320 | pdxB | -2.0 | -12.0 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b0438 | clpX | -2.0 | -2.4 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b3621 | rfaC | -2.0 | -1.9 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b4025 | pgi | -2.0 | -10.7 | glucose-6-phosphate isomerase (NCBI) | compare |
| b4242 | mgtA | -1.8 | -7.9 | magnesium transporter (NCBI) | compare |
| b1693 | aroD | -1.8 | -7.4 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0033 | carB | -1.8 | -5.0 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b3916 | pfkA | -1.8 | -3.1 | 6-phosphofructokinase (NCBI) | compare |
| b2839 | lysR | -1.7 | -5.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0688 | pgm | -1.7 | -3.5 | phosphoglucomutase (NCBI) | compare |
| b1273 | yciN | -1.7 | -2.4 | hypothetical protein (NCBI) | compare |
| b1192 | ldcA | -1.7 | -3.3 | L,D-carboxypeptidase A (NCBI) | compare |
| b0720 | gltA | -1.7 | -8.0 | citrate synthase (NCBI) | compare |
| b3620 | rfaF | -1.7 | -3.5 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b2175 | spr | -1.7 | -3.1 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b3829 | metE | -1.7 | -13.9 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b0051 | ksgA | -1.6 | -5.1 | dimethyladenosine transferase (NCBI) | compare |
| b1185 | dsbB | -1.6 | -3.4 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b0632 | dacA | -1.6 | -8.7 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b2832 | ygdQ | -1.6 | -10.0 | predicted inner membrane protein (NCBI) | compare |
| b3941 | metF | -1.6 | -10.6 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b0889 | lrp | -1.6 | -4.4 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b3787 | rffD | -1.6 | -8.9 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b4171 | miaA | -1.6 | -2.9 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b2750 | cysC | -1.6 | -6.8 | adenylylsulfate kinase (NCBI) | compare |
| b2414 | cysK | -1.6 | -9.5 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b4146 | yjeK | -1.5 | -2.0 | predicted lysine aminomutase (NCBI) | compare |
| b3164 | pnp | -1.5 | -3.5 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b1438 | ydcQ | -1.5 | -2.2 | predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b0928 | aspC | -1.5 | -7.1 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b0926 | ycbK | -1.5 | -7.5 | hypothetical protein (NCBI) | compare |
| b0730 | mngR | -1.5 | -2.2 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b1865 | nudB | -1.5 | -2.1 | dATP pyrophosphohydrolase (NCBI) | compare |
| b3619 | rfaD | -1.5 | -1.0 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b3838 | tatB | -1.4 | -6.7 | sec-independent translocase (NCBI) | compare |
| b2022 | hisB | -1.4 | -6.8 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b4218 | ytfL | -1.4 | -7.8 | predicted inner membrane protein (NCBI) | compare |
| b3786 | rffE | -1.4 | -8.9 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b3229 | sspA | -1.4 | -4.3 | stringent starvation protein A (NCBI) | compare |
| b2784 | relA | -1.4 | -7.9 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b2023 | hisH | -1.4 | -6.3 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b3828 | metR | -1.4 | -9.4 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b3924 | fpr | -1.3 | -8.7 | ferredoxin-NADP reductase (NCBI) | compare |
| b3082 | ygjM | -1.3 | -1.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2600 | tyrA | -1.3 | -7.7 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b2567 | rnc | -1.3 | -0.8 | ribonuclease III (NCBI) | compare |
| b3774 | ilvC | -1.3 | -10.5 | ketol-acid reductoisomerase (NCBI) | compare |
| b2764 | cysJ | -1.2 | -7.7 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b1231 | tyrT | -1.2 | -1.5 | tRNA-Tyr (NCBI) | compare |
| b2064 | asmA | -1.2 | -5.6 | predicted assembly protein (NCBI) | compare |
| b4375 | prfC | -1.2 | -4.8 | peptide chain release factor 3 (NCBI) | compare |
| b3021 | ygiT | -1.2 | -2.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0437 | clpP | -1.2 | -0.8 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b3741 | gidA | -1.2 | -2.1 | glucose-inhibited division protein A (NCBI) | compare |
| b3791 | rffA | -1.2 | -4.3 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b0242 | proB | -1.2 | -7.0 | gamma-glutamyl kinase (NCBI) | compare |
| b0200 | gmhB | -1.2 | -0.8 | hypothetical protein (NCBI) | compare |
| b3771 | ilvD | -1.2 | -9.2 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2763 | cysI | -1.2 | -6.6 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b1850 | eda | -1.2 | -1.7 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b4246 | pyrL | -1.1 | -1.0 | pyrBI operon leader peptide (NCBI) | compare |
| b1176 | minC | -1.1 | -3.1 | septum formation inhibitor (NCBI) | compare |
| b1863 | ruvC | -1.1 | -1.0 | Holliday junction resolvase (NCBI) | compare |
| b3860 | dsbA | -1.1 | -5.8 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b1150 | ymfR | -1.1 | -1.4 | e14 prophage; predicted protein (NCBI) | compare |
| b0243 | proA | -1.1 | -7.5 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0088 | murD | -1.1 | -2.8 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b3613 | yibP | -1.1 | -1.4 | putative membrane protein (VIMSS) | compare |
| b2313 | cvpA | -1.1 | -4.4 | membrane protein required for colicin V production (NCBI) | compare |
| b2818 | argA | -1.1 | -6.8 | N-acetylglutamate synthase (NCBI) | compare |
| b2024 | hisA | -1.1 | -2.0 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3839 | tatC | -1.1 | -2.2 | TatABCE protein translocation system subunit (NCBI) | compare |
| b2020 | hisD | -1.1 | -6.6 | histidinol dehydrogenase (NCBI) | compare |
| b3957 | argE | -1.1 | -8.3 | acetylornithine deacetylase (NCBI) | compare |
| b3792 | wzxE | -1.1 | -2.7 | O-antigen translocase (NCBI) | compare |
| b0957 | ompA | -1.0 | -3.1 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b1084 | rne | -1.0 | -3.7 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b3958 | argC | -1.0 | -7.6 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b3959 | argB | -1.0 | -7.4 | acetylglutamate kinase (RefSeq) | compare |
| b1262 | trpC | -1.0 | -3.6 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b2479 | gcvR | -1.0 | -5.7 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2504 | yfgG | -1.0 | -1.3 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b2021 | hisC | -1.0 | -3.5 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b1936 | intG | -1.0 | -1.5 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b0912 | ihfB | -1.0 | -0.6 | integration host factor subunit beta (NCBI) | compare |
| b3609 | secB | -1.0 | -2.2 | export protein SecB (NCBI) | compare |
| b4414 | tff | -1.0 | -1.4 | unknown RNA (NCBI) | compare |
| b4655 | ythA | -1.0 | -1.5 | expressed protein (RefSeq) | compare |
| b0729 | sucD | -0.9 | -2.4 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b3977 | tyrU | -0.9 | -0.8 | tRNA-Tyr (NCBI) | compare |
| b1862 | yebB | -0.9 | -3.7 | orf, hypothetical protein (VIMSS) | compare |
| b3770 | ilvE | -0.9 | -7.2 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b2516 | yfgA | -0.9 | -4.6 | hypothetical protein (NCBI) | compare |
| b3027 | ygiZ | -0.9 | -0.6 | conserved inner membrane protein (NCBI) | compare |
| b3368 | cysG | -0.9 | -7.7 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b1346 | ydaQ | -0.9 | -1.6 | orf, hypothetical protein (VIMSS) | compare |
| b3469 | zntA | -0.9 | -5.7 | zinc, cobalt and lead efflux system (NCBI) | compare |
| b0053 | surA | -0.9 | -2.9 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b2620 | smpB | -0.9 | -0.8 | SsrA-binding protein (NCBI) | compare |
| b0142 | folK | -0.9 | -0.6 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b2935 | tktA | -0.9 | -1.5 | transketolase 1, thiamin-binding (NCBI) | compare |
| b1506 | yneL | -0.9 | -1.7 | predicted transcriptional regulator (NCBI) | compare |
| b1235 | rssB | -0.9 | -3.1 | response regulator of RpoS (NCBI) | compare |
| b3911 | cpxA | -0.9 | -5.4 | two-component sensor protein (NCBI) | compare |
| b3706 | trmE | -0.8 | -2.6 | tRNA modification GTPase (NCBI) | compare |
| b3527 | yhjJ | -0.8 | -7.5 | predicted zinc-dependent peptidase (NCBI) | compare |
| b2363 | yfdT | -0.8 | -1.7 | CPS-53 (KpLE1) prophage; predicted protein (NCBI) | compare |
| b2025 | hisF | -0.8 | -2.8 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b3794 | rffM | -0.8 | -3.4 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b4676 | yoaK | -0.8 | -0.6 | expressed protein (RefSeq) | compare |
| b0400 | phoR | -0.8 | -5.3 | sensory histidine kinase in two-component regulatory system with PhoB (NCBI) | compare |
| b1241 | adhE | -0.8 | -6.0 | fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) | compare |
| b4179 | vacB | -0.8 | -3.7 | putative enzyme (VIMSS) | compare |
| b4202 | rpsR | -0.8 | -0.7 | 30S ribosomal protein S18 (NCBI) | compare |
| b0001 | thrL | -0.8 | -0.8 | thr operon leader peptide (NCBI) | compare |
| b1107 | nagZ | -0.8 | -3.4 | beta-hexosaminidase (NCBI) | compare |
| b3784 | rfe | -0.8 | -5.2 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b2019 | hisG | -0.8 | -3.5 | ATP phosphoribosyltransferase (NCBI) | compare |
| b2683 | ygaH | -0.8 | -2.4 | predicted inner membrane protein (NCBI) | compare |
| b1524 | yneH | -0.8 | -1.1 | predicted glutaminase (NCBI) | compare |
| b3764 | yifE | -0.8 | -3.0 | hypothetical protein (NCBI) | compare |
| b2144 | sanA | -0.8 | -6.1 | hypothetical protein (NCBI) | compare |
| b1095 | fabF | -0.8 | -4.4 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b1290 | sapF | -0.8 | -1.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0726 | sucA | -0.7 | -3.3 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b2614 | grpE | -0.7 | -2.3 | heat shock protein (NCBI) | compare |
| b2752 | cysD | -0.7 | -3.0 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b4513 | kdpF | -0.7 | -1.3 | potassium ion accessory transporter subunit (NCBI) | compare |
| b0149 | mrcB | -0.7 | -4.9 | penicillin-binding protein 1b (NCBI) | compare |
| b3204 | ptsN | -0.7 | -2.5 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b3404 | envZ | -0.7 | -4.7 | osmolarity sensor protein (NCBI) | compare |
| b2500 | purN | -0.7 | -3.6 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b3375 | yhfR | -0.7 | -4.5 | putative transcriptional regulator (VIMSS) | compare |
| b3252 | yhdA | -0.7 | -5.9 | conserved inner membrane protein (NCBI) | compare |
| b2599 | pheA | -0.7 | -5.0 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b2611 | ypjD | -0.7 | -4.0 | predicted inner membrane protein (RefSeq) | compare |
| b3237 | argR | -0.7 | -2.4 | arginine repressor (NCBI) | compare |
| b2340 | sixA | -0.7 | -2.9 | phosphohistidine phosphatase (NCBI) | compare |
| b0075 | leuL | -0.7 | -4.6 | leu operon leader peptide (NCBI) | compare |
| b0439 | lon | -0.7 | -2.3 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b1263 | trpD | -0.7 | -1.8 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b4701 | sokX | -0.7 | -0.7 | sok-related sRNA, function unknown (RefSeq) | compare |
| b3842 | rfaH | -0.7 | -2.3 | transcriptional activator RfaH (NCBI) | compare |
| b1232 | purU | -0.7 | -4.1 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b2215 | ompC | -0.7 | -0.5 | outer membrane porin protein C (NCBI) | compare |
| b0101 | yacG | -0.7 | -3.0 | zinc-binding protein (NCBI) | compare |
| b2017 | yefM | -0.7 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b2071 | yegJ | -0.7 | -1.7 | hypothetical protein (NCBI) | compare |
| b3162 | deaD | -0.7 | -2.7 | inducible ATP-independent RNA helicase (VIMSS) | compare |