| | gene | name | fitness | t score | description | |
|---|
| b1281 | pyrF | -3.7 | -2.5 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0004 | thrC | -3.5 | -15.6 | threonine synthase (NCBI) | compare |
| b3172 | argG | -3.4 | -15.5 | argininosuccinate synthase (NCBI) | compare |
| b0003 | thrB | -3.4 | -10.2 | homoserine kinase (NCBI) | compare |
| b3960 | argH | -3.4 | -19.1 | argininosuccinate lyase (NCBI) | compare |
| b3229 | sspA | -3.3 | -3.2 | stringent starvation protein A (NCBI) | compare |
| b1865 | nudB | -3.2 | -2.8 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1192 | ldcA | -2.9 | -2.0 | L,D-carboxypeptidase A (NCBI) | compare |
| b0002 | thrA | -2.8 | -16.2 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b1830 | prc | -2.8 | -1.9 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b1062 | pyrC | -2.8 | -6.2 | dihydroorotase (NCBI) | compare |
| b4245 | pyrB | -2.6 | -3.6 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b2838 | lysA | -2.6 | -16.9 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b2329 | aroC | -2.6 | -7.6 | chorismate synthase (NCBI) | compare |
| b0407 | yajC | -2.5 | -3.8 | preprotein translocase subunit YajC (NCBI) | compare |
| b4006 | purH | -2.5 | -13.1 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0908 | aroA | -2.5 | -11.9 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b4402 | yjjY | -2.4 | -1.6 | hypothetical protein (NCBI) | compare |
| b2501 | ppk | -2.4 | -9.5 | polyphosphate kinase (NCBI) | compare |
| b0907 | serC | -2.4 | -9.3 | phosphoserine aminotransferase (NCBI) | compare |
| b3956 | ppc | -2.3 | -18.3 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b4388 | serB | -2.3 | -8.3 | 3-phosphoserine phosphatase (NCBI) | compare |
| b3052 | rfaE | -2.2 | -1.5 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2808 | gcvA | -2.2 | -5.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2318 | truA | -2.2 | -3.8 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2913 | serA | -2.2 | -9.3 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2912 | ygfA | -2.1 | -3.1 | putative ligase (VIMSS) | compare |
| b2499 | purM | -2.1 | -5.8 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b4242 | mgtA | -2.1 | -7.2 | magnesium transporter (NCBI) | compare |
| b3620 | rfaF | -2.1 | -1.4 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b4374 | yjjG | -2.1 | -11.2 | nucleotidase (NCBI) | compare |
| b4005 | purD | -2.0 | -9.0 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b0033 | carB | -2.0 | -4.5 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0523 | purE | -2.0 | -4.6 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b3924 | fpr | -2.0 | -9.2 | ferredoxin-NADP reductase (NCBI) | compare |
| b3979 | thrT | -1.9 | -0.7 | tRNA-Thr (NCBI) | compare |
| b3926 | glpK | -1.9 | -14.5 | glycerol kinase (NCBI) | compare |
| b2557 | purL | -1.9 | -11.3 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0522 | purK | -1.9 | -10.2 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2818 | argA | -1.9 | -10.8 | N-acetylglutamate synthase (NCBI) | compare |
| b1293 | sapB | -1.9 | -1.7 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3870 | glnA | -1.8 | -4.5 | glutamine synthetase (NCBI) | compare |
| b1185 | dsbB | -1.8 | -3.3 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b1936 | intG | -1.8 | -1.2 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b0945 | pyrD | -1.8 | -2.1 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0720 | gltA | -1.8 | -7.3 | citrate synthase (NCBI) | compare |
| b0032 | carA | -1.7 | -4.3 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b2312 | purF | -1.7 | -7.1 | amidophosphoribosyltransferase (NCBI) | compare |
| b3957 | argE | -1.7 | -13.8 | acetylornithine deacetylase (NCBI) | compare |
| b4699 | fnrS | -1.7 | -1.3 | FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) | compare |
| b0222 | lpcA | -1.7 | -1.1 | phosphoheptose isomerase (NCBI) | compare |
| b3912 | cpxR | -1.7 | -6.9 | DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) | compare |
| b2175 | spr | -1.7 | -3.5 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b2762 | cysH | -1.7 | -8.8 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0051 | ksgA | -1.7 | -5.5 | dimethyladenosine transferase (NCBI) | compare |
| b3931 | hslU | -1.7 | -10.8 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b3932 | hslV | -1.7 | -9.9 | ATP-dependent protease peptidase subunit (NCBI) | compare |
| b4171 | miaA | -1.7 | -3.3 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b0015 | dnaJ | -1.6 | -9.9 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b1677 | lpp | -1.6 | -2.6 | murein lipoprotein (NCBI) | compare |
| b4375 | prfC | -1.6 | -5.6 | peptide chain release factor 3 (NCBI) | compare |
| b0145 | dksA | -1.6 | -3.5 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b3791 | rffA | -1.6 | -4.7 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b1273 | yciN | -1.6 | -2.2 | hypothetical protein (NCBI) | compare |
| b2476 | purC | -1.6 | -3.6 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3642 | pyrE | -1.6 | -1.5 | orotate phosphoribosyltransferase (NCBI) | compare |
| b1575 | dicB | -1.6 | -1.4 | Qin prophage; cell division inhibition protein (NCBI) | compare |
| b3842 | rfaH | -1.6 | -4.9 | transcriptional activator RfaH (NCBI) | compare |
| b3934 | cytR | -1.5 | -10.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0688 | pgm | -1.5 | -3.4 | phosphoglucomutase (NCBI) | compare |
| b4175 | hflC | -1.5 | -9.1 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b4702 | mgtL | -1.5 | -1.0 | regulatory leader peptide for mgtA (NCBI) | compare |
| b3959 | argB | -1.5 | -9.2 | acetylglutamate kinase (RefSeq) | compare |
| b0049 | apaH | -1.5 | -2.3 | diadenosinetetraphosphatase (NCBI) | compare |
| b0438 | clpX | -1.5 | -3.0 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b4214 | cysQ | -1.5 | -10.6 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b0386 | proC | -1.5 | -3.6 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2764 | cysJ | -1.4 | -7.9 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b1095 | fabF | -1.4 | -7.1 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b4202 | rpsR | -1.4 | -0.9 | 30S ribosomal protein S18 (NCBI) | compare |
| b4174 | hflK | -1.4 | -8.6 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b0437 | clpP | -1.4 | -1.3 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b4481 | rffT | -1.4 | -3.6 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3621 | rfaC | -1.4 | -1.0 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3281 | aroE | -1.4 | -9.4 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b3790 | rffC | -1.4 | -3.4 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b4218 | ytfL | -1.3 | -7.9 | predicted inner membrane protein (NCBI) | compare |
| b2564 | pdxJ | -1.3 | -4.7 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b3786 | rffE | -1.3 | -8.3 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b2750 | cysC | -1.3 | -6.6 | adenylylsulfate kinase (NCBI) | compare |
| b3261 | fis | -1.3 | -1.7 | DNA-binding protein Fis (NCBI) | compare |
| b2017 | yefM | -1.3 | -1.1 | orf, hypothetical protein (VIMSS) | compare |
| b4025 | pgi | -1.3 | -7.9 | glucose-6-phosphate isomerase (NCBI) | compare |
| b1693 | aroD | -1.3 | -5.4 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b3792 | wzxE | -1.3 | -2.7 | O-antigen translocase (NCBI) | compare |
| b1332 | ynaJ | -1.3 | -0.6 | predicted inner membrane protein (NCBI) | compare |
| b3916 | pfkA | -1.2 | -2.1 | 6-phosphofructokinase (NCBI) | compare |
| b3741 | gidA | -1.2 | -2.3 | glucose-inhibited division protein A (NCBI) | compare |
| b4146 | yjeK | -1.2 | -0.8 | predicted lysine aminomutase (NCBI) | compare |
| b3169 | nusA | -1.2 | -1.9 | transcription elongation factor NusA (NCBI) | compare |
| b1103 | ycfF | -1.2 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b0990 | cspG | -1.2 | -0.7 | DNA-binding transcriptional regulator (NCBI) | compare |
| b1563 | relE | -1.2 | -1.9 | Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) | compare |
| b0912 | ihfB | -1.2 | -0.8 | integration host factor subunit beta (NCBI) | compare |
| b1291 | sapD | -1.2 | -1.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1438 | ydcQ | -1.2 | -4.6 | predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b2763 | cysI | -1.2 | -6.7 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b3958 | argC | -1.1 | -7.9 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b0439 | lon | -1.1 | -3.4 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3162 | deaD | -1.1 | -4.3 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b0441 | ppiD | -1.1 | -8.5 | peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI) | compare |
| b0767 | ybhE | -1.1 | -3.7 | 6-phosphogluconolactonase (NCBI) | compare |
| b3631 | rfaG | -1.1 | -6.0 | glucosyltransferase I (NCBI) | compare |
| b1260 | trpA | -1.1 | -5.3 | tryptophan synthase subunit alpha (NCBI) | compare |
| b3784 | rfe | -1.1 | -7.3 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b1292 | sapC | -1.1 | -1.8 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2839 | lysR | -1.1 | -4.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2330 | yfcB | -1.1 | -2.1 | putative adenine-specific methylase (VIMSS) | compare |
| b2313 | cvpA | -1.0 | -2.9 | membrane protein required for colicin V production (NCBI) | compare |
| b3794 | rffM | -1.0 | -4.8 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b2414 | cysK | -1.0 | -5.6 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b0001 | thrL | -1.0 | -1.4 | thr operon leader peptide (NCBI) | compare |
| b1290 | sapF | -1.0 | -1.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0101 | yacG | -1.0 | -2.4 | zinc-binding protein (NCBI) | compare |
| b4676 | yoaK | -1.0 | -0.5 | expressed protein (RefSeq) | compare |
| b3706 | trmE | -1.0 | -3.7 | tRNA modification GTPase (NCBI) | compare |
| b1183 | umuD | -1.0 | -1.8 | DNA polymerase V, subunit D (NCBI) | compare |
| b3619 | rfaD | -1.0 | -0.7 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b1346 | ydaQ | -1.0 | -0.9 | orf, hypothetical protein (VIMSS) | compare |
| b2832 | ygdQ | -1.0 | -4.9 | predicted inner membrane protein (NCBI) | compare |
| b3082 | ygjM | -1.0 | -0.9 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2259 | pmrD | -1.0 | -1.2 | polymyxin resistance protein B (VIMSS) | compare |
| b0782 | moaB | -1.0 | -2.7 | molybdopterin biosynthesis protein B (NCBI) | compare |
| b3389 | aroB | -1.0 | -5.9 | 3-dehydroquinate synthase (NCBI) | compare |
| b0632 | dacA | -1.0 | -5.1 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b2614 | grpE | -1.0 | -2.4 | heat shock protein (NCBI) | compare |
| b3941 | metF | -1.0 | -8.0 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b1726 | yniB | -1.0 | -2.2 | predicted inner membrane protein (NCBI) | compare |
| b1831 | proQ | -1.0 | -2.9 | putative solute/DNA competence effector (NCBI) | compare |
| b3368 | cysG | -1.0 | -8.3 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b2952 | yggT | -0.9 | -4.3 | predicted inner membrane protein (NCBI) | compare |
| b4184 | yjfL | -0.9 | -2.5 | conserved inner membrane protein (NCBI) | compare |
| b3787 | rffD | -0.9 | -5.6 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b0242 | proB | -0.9 | -4.6 | gamma-glutamyl kinase (NCBI) | compare |
| b3021 | ygiT | -0.9 | -2.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1084 | rne | -0.9 | -3.2 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b3237 | argR | -0.9 | -2.6 | arginine repressor (NCBI) | compare |
| b0840 | deoR | -0.9 | -4.3 | DNA-binding transcriptional repressor (NCBI) | compare |
| b0928 | aspC | -0.9 | -4.4 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b3961 | oxyR | -0.9 | -7.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1111 | ycfQ | -0.9 | -2.8 | orf, hypothetical protein (VIMSS) | compare |
| b3829 | metE | -0.9 | -7.5 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b3032 | cpdA | -0.9 | -5.2 | cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) | compare |
| b2320 | pdxB | -0.9 | -5.3 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b2620 | smpB | -0.9 | -0.7 | SsrA-binding protein (NCBI) | compare |
| b4431 | rprA | -0.9 | -1.8 | Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) | compare |
| b3838 | tatB | -0.9 | -4.3 | sec-independent translocase (NCBI) | compare |
| b4179 | vacB | -0.9 | -3.9 | putative enzyme (VIMSS) | compare |
| b2516 | yfgA | -0.9 | -4.4 | hypothetical protein (NCBI) | compare |
| b0406 | tgt | -0.9 | -3.9 | queuine tRNA-ribosyltransferase (NCBI) | compare |
| b0243 | proA | -0.8 | -5.6 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b1304 | pspA | -0.8 | -2.1 | regulatory protein for phage-shock-protein operon (NCBI) | compare |
| b1850 | eda | -0.8 | -1.9 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b3649 | rpoZ | -0.8 | -2.7 | DNA-directed RNA polymerase subunit omega (NCBI) | compare |
| b4140 | b4140 | -0.8 | -4.9 | orf, hypothetical protein (VIMSS) | compare |
| b4217 | ytfK | -0.8 | -3.8 | orf, hypothetical protein (VIMSS) | compare |
| b4557 | yidD | -0.8 | -3.3 | hypothetical protein (NCBI) | compare |
| b2181 | yejG | -0.8 | -2.3 | hypothetical protein (NCBI) | compare |
| b1261 | trpB | -0.8 | -1.4 | tryptophan synthase subunit beta (NCBI) | compare |
| b0200 | gmhB | -0.8 | -0.5 | hypothetical protein (NCBI) | compare |
| b3163 | nlpI | -0.8 | -3.0 | hypothetical protein (NCBI) | compare |
| b2790 | yqcA | -0.8 | -3.1 | flavodoxin (NCBI) | compare |
| b1656 | sodB | -0.8 | -2.5 | superoxide dismutase, Fe (NCBI) | compare |
| b3497 | yhiQ | -0.8 | -4.3 | predicted SAM-dependent methyltransferase (NCBI) | compare |
| b3545 | proK | -0.8 | -1.9 | tRNA-Pro (NCBI) | compare |
| b3761 | trpT | -0.8 | -1.4 | tRNA-Trp (NCBI) | compare |
| b4519 | icdC | -0.8 | -3.1 | no description | compare |
| b1108 | ycfP | -0.8 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b3099 | yqjE | -0.8 | -2.8 | conserved inner membrane protein (NCBI) | compare |
| b4436 | ryeC | -0.8 | -1.8 | Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) | compare |
| b3860 | dsbA | -0.7 | -3.7 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b0683 | fur | -0.7 | -0.7 | ferric uptake regulator (NCBI) | compare |
| b0999 | cbpM | -0.7 | -1.8 | modulator of CbpA co-chaperone (NCBI) | compare |
| b2683 | ygaH | -0.7 | -3.9 | predicted inner membrane protein (NCBI) | compare |
| b3609 | secB | -0.7 | -1.9 | export protein SecB (NCBI) | compare |
| b0889 | lrp | -0.7 | -1.4 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b4642 | yoeD | -0.7 | -1.3 | no description | compare |
| b3469 | zntA | -0.7 | -4.7 | zinc, cobalt and lead efflux system (NCBI) | compare |
| b3828 | metR | -0.7 | -5.1 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b3387 | dam | -0.7 | -4.0 | DNA adenine methylase (NCBI) | compare |
| b1584 | speG | -0.7 | -4.7 | spermidine N1-acetyltransferase (NCBI) | compare |
| b3611 | yibN | -0.7 | -2.3 | predicted rhodanese-related sulfurtransferase (NCBI) | compare |
| b0436 | tig | -0.7 | -4.5 | trigger factor (NCBI) | compare |
| b1684 | sufA | -0.7 | -2.6 | iron-sulfur cluster assembly scaffold protein (NCBI) | compare |
| b3260 | dusB | -0.7 | -3.8 | tRNA-dihydrouridine synthase B (NCBI) | compare |
| b4045 | yjbJ | -0.7 | -1.4 | predicted stress response protein (NCBI) | compare |
| b0605 | ahpC | -0.7 | -3.3 | alkyl hydroperoxide reductase, C22 subunit (NCBI) | compare |
| b2741 | rpoS | -0.7 | -3.6 | RNA polymerase sigma factor (NCBI) | compare |
| b3404 | envZ | -0.7 | -4.8 | osmolarity sensor protein (NCBI) | compare |
| b0389 | yaiA | -0.7 | -1.9 | hypothetical protein (NCBI) | compare |