| | gene | name | fitness | t score | description | |
|---|
| b2476 | purC | -5.0 | -4.7 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b2499 | purM | -4.6 | -9.3 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b0907 | serC | -4.4 | -10.1 | phosphoserine aminotransferase (NCBI) | compare |
| b3172 | argG | -4.0 | -17.3 | argininosuccinate synthase (NCBI) | compare |
| b3960 | argH | -4.0 | -16.1 | argininosuccinate lyase (NCBI) | compare |
| b2501 | ppk | -4.0 | -8.0 | polyphosphate kinase (NCBI) | compare |
| b2557 | purL | -3.9 | -14.4 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b4388 | serB | -3.9 | -10.1 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2312 | purF | -3.9 | -9.2 | amidophosphoribosyltransferase (NCBI) | compare |
| b2838 | lysA | -3.8 | -17.8 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b4005 | purD | -3.8 | -15.8 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b0523 | purE | -3.7 | -5.3 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2913 | serA | -3.7 | -12.3 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b4006 | purH | -3.7 | -14.9 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b1062 | pyrC | -3.6 | -4.9 | dihydroorotase (NCBI) | compare |
| b0004 | thrC | -3.6 | -15.5 | threonine synthase (NCBI) | compare |
| b0002 | thrA | -3.5 | -17.6 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b0003 | thrB | -3.5 | -9.1 | homoserine kinase (NCBI) | compare |
| b2329 | aroC | -3.2 | -9.0 | chorismate synthase (NCBI) | compare |
| b0720 | gltA | -3.1 | -10.0 | citrate synthase (NCBI) | compare |
| b3956 | ppc | -3.0 | -21.2 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b3860 | dsbA | -3.0 | -9.0 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b1241 | adhE | -3.0 | -17.3 | fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) | compare |
| b1865 | nudB | -2.9 | -2.0 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1281 | pyrF | -2.9 | -2.7 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0908 | aroA | -2.9 | -12.0 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3870 | glnA | -2.9 | -3.4 | glutamine synthetase (NCBI) | compare |
| b2188 | yejM | -2.9 | -14.2 | predicted hydrolase, inner membrane (NCBI) | compare |
| b0928 | aspC | -2.9 | -11.6 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b0051 | ksgA | -2.9 | -5.7 | dimethyladenosine transferase (NCBI) | compare |
| b1192 | ldcA | -2.9 | -2.0 | L,D-carboxypeptidase A (NCBI) | compare |
| b0145 | dksA | -2.8 | -2.7 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b4025 | pgi | -2.8 | -13.3 | glucose-6-phosphate isomerase (NCBI) | compare |
| b1346 | ydaQ | -2.7 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b3389 | aroB | -2.7 | -12.3 | 3-dehydroquinate synthase (NCBI) | compare |
| b2912 | ygfA | -2.6 | -2.5 | putative ligase (VIMSS) | compare |
| b0688 | pgm | -2.6 | -3.0 | phosphoglucomutase (NCBI) | compare |
| b4245 | pyrB | -2.6 | -3.0 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b3281 | aroE | -2.5 | -13.9 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2784 | relA | -2.4 | -13.1 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b0889 | lrp | -2.4 | -3.5 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b2808 | gcvA | -2.4 | -4.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2017 | yefM | -2.3 | -1.3 | orf, hypothetical protein (VIMSS) | compare |
| b1185 | dsbB | -2.3 | -2.8 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b1830 | prc | -2.3 | -3.1 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b2564 | pdxJ | -2.3 | -8.2 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b4402 | yjjY | -2.3 | -1.6 | hypothetical protein (NCBI) | compare |
| b0407 | yajC | -2.2 | -3.5 | preprotein translocase subunit YajC (NCBI) | compare |
| b0728 | sucC | -2.2 | -6.7 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b1850 | eda | -2.2 | -3.6 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b4171 | miaA | -2.2 | -2.9 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b0729 | sucD | -2.2 | -4.4 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b3052 | rfaE | -2.2 | -1.5 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2414 | cysK | -2.2 | -12.8 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b3229 | sspA | -2.1 | -4.2 | stringent starvation protein A (NCBI) | compare |
| b4242 | mgtA | -2.1 | -6.1 | magnesium transporter (NCBI) | compare |
| b0564 | appY | -2.1 | -1.0 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0049 | apaH | -2.1 | -2.0 | diadenosinetetraphosphatase (NCBI) | compare |
| b4218 | ytfL | -2.1 | -11.3 | predicted inner membrane protein (NCBI) | compare |
| b1438 | ydcQ | -2.1 | -3.3 | predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b0033 | carB | -2.1 | -2.8 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0032 | carA | -2.1 | -3.4 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b2762 | cysH | -2.1 | -10.9 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b1677 | lpp | -2.0 | -3.2 | murein lipoprotein (NCBI) | compare |
| b0052 | pdxA | -2.0 | -12.3 | 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) | compare |
| b2818 | argA | -1.9 | -9.2 | N-acetylglutamate synthase (NCBI) | compare |
| b1175 | minD | -1.9 | -5.1 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b0386 | proC | -1.9 | -3.7 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2763 | cysI | -1.9 | -10.6 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b3912 | cpxR | -1.9 | -8.0 | DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) | compare |
| b3469 | zntA | -1.9 | -9.5 | zinc, cobalt and lead efflux system (NCBI) | compare |
| b1693 | aroD | -1.9 | -6.1 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b3957 | argE | -1.8 | -15.1 | acetylornithine deacetylase (NCBI) | compare |
| b3958 | argC | -1.8 | -12.8 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b0632 | dacA | -1.8 | -8.6 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b3959 | argB | -1.8 | -12.7 | acetylglutamate kinase (RefSeq) | compare |
| b4174 | hflK | -1.8 | -9.8 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b3932 | hslV | -1.8 | -11.5 | ATP-dependent protease peptidase subunit (NCBI) | compare |
| b2764 | cysJ | -1.8 | -11.3 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b0015 | dnaJ | -1.8 | -9.8 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b2320 | pdxB | -1.8 | -9.2 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b2318 | truA | -1.8 | -3.2 | tRNA pseudouridine synthase A (NCBI) | compare |
| b3931 | hslU | -1.8 | -11.5 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b3620 | rfaF | -1.7 | -1.7 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b0902 | pflA | -1.7 | -8.8 | pyruvate formate lyase activating enzyme 1 (NCBI) | compare |
| b0945 | pyrD | -1.7 | -2.5 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0438 | clpX | -1.7 | -2.2 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b2750 | cysC | -1.7 | -6.7 | adenylylsulfate kinase (NCBI) | compare |
| b3941 | metF | -1.7 | -10.9 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b3642 | pyrE | -1.7 | -1.1 | orotate phosphoribosyltransferase (NCBI) | compare |
| b2871 | ygeX | -1.6 | -5.4 | diaminopropionate ammonia-lyase (NCBI) | compare |
| b0903 | pflB | -1.6 | -11.2 | pyruvate formate lyase I (NCBI) | compare |
| b0406 | tgt | -1.6 | -5.8 | queuine tRNA-ribosyltransferase (NCBI) | compare |
| b3021 | ygiT | -1.6 | -2.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3791 | rffA | -1.6 | -4.1 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b1260 | trpA | -1.5 | -5.3 | tryptophan synthase subunit alpha (NCBI) | compare |
| b1709 | btuD | -1.5 | -1.7 | vitamin B12-transporter ATPase (NCBI) | compare |
| b1863 | ruvC | -1.5 | -1.0 | Holliday junction resolvase (NCBI) | compare |
| b0926 | ycbK | -1.5 | -5.0 | hypothetical protein (NCBI) | compare |
| b3611 | yibN | -1.5 | -4.5 | predicted rhodanese-related sulfurtransferase (NCBI) | compare |
| b4175 | hflC | -1.5 | -8.1 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b3790 | rffC | -1.5 | -3.0 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b3237 | argR | -1.5 | -5.1 | arginine repressor (NCBI) | compare |
| b3204 | ptsN | -1.5 | -5.5 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b0437 | clpP | -1.5 | -1.0 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b3368 | cysG | -1.4 | -12.1 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b3829 | metE | -1.4 | -11.5 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b2424 | cysU | -1.4 | -4.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2839 | lysR | -1.4 | -3.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3359 | argD | -1.4 | -11.7 | bifunctional acetylornithine aminotransferase/ succinyldiaminopimelate aminotransferase (NCBI) | compare |
| b0222 | lpcA | -1.4 | -1.3 | phosphoheptose isomerase (NCBI) | compare |
| b0441 | ppiD | -1.4 | -10.0 | peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI) | compare |
| b1261 | trpB | -1.4 | -2.6 | tryptophan synthase subunit beta (NCBI) | compare |
| b0957 | ompA | -1.4 | -4.1 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b1235 | rssB | -1.4 | -5.0 | response regulator of RpoS (NCBI) | compare |
| b4202 | rpsR | -1.4 | -0.9 | 30S ribosomal protein S18 (NCBI) | compare |
| b1290 | sapF | -1.3 | -1.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3916 | pfkA | -1.3 | -1.8 | 6-phosphofructokinase (NCBI) | compare |
| b2330 | yfcB | -1.3 | -2.2 | putative adenine-specific methylase (VIMSS) | compare |
| b3838 | tatB | -1.3 | -5.9 | sec-independent translocase (NCBI) | compare |
| b1095 | fabF | -1.3 | -6.0 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b4238 | nrdD | -1.3 | -10.6 | anaerobic ribonucleoside triphosphate reductase (NCBI) | compare |
| b2313 | cvpA | -1.3 | -4.5 | membrane protein required for colicin V production (NCBI) | compare |
| b3741 | gidA | -1.3 | -1.5 | glucose-inhibited division protein A (NCBI) | compare |
| b3786 | rffE | -1.3 | -8.4 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b0400 | phoR | -1.3 | -7.8 | sensory histidine kinase in two-component regulatory system with PhoB (NCBI) | compare |
| b2952 | yggT | -1.2 | -5.4 | predicted inner membrane protein (NCBI) | compare |
| b3911 | cpxA | -1.2 | -5.3 | two-component sensor protein (NCBI) | compare |
| b4481 | rffT | -1.2 | -3.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3828 | metR | -1.2 | -8.4 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b3621 | rfaC | -1.2 | -1.6 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b1613 | manA | -1.2 | -2.1 | mannose-6-phosphate isomerase (VIMSS) | compare |
| b1332 | ynaJ | -1.2 | -0.6 | predicted inner membrane protein (NCBI) | compare |
| b2021 | hisC | -1.2 | -4.7 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b3792 | wzxE | -1.2 | -2.4 | O-antigen translocase (NCBI) | compare |
| b2516 | yfgA | -1.2 | -5.7 | hypothetical protein (NCBI) | compare |
| b0142 | folK | -1.2 | -0.4 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b0912 | ihfB | -1.2 | -0.8 | integration host factor subunit beta (NCBI) | compare |
| b2600 | tyrA | -1.1 | -4.2 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b4237 | nrdG | -1.1 | -7.5 | anaerobic ribonucleotide reductase activating protein (NCBI) | compare |
| b3169 | nusA | -1.1 | -1.7 | transcription elongation factor NusA (NCBI) | compare |
| b2832 | ygdQ | -1.1 | -6.7 | predicted inner membrane protein (NCBI) | compare |
| b0683 | fur | -1.1 | -1.3 | ferric uptake regulator (NCBI) | compare |
| b3673 | emrD | -1.1 | -8.5 | 2-module integral membrane pump; multidrug resistance (VIMSS) | compare |
| b3375 | yhfR | -1.1 | -7.5 | putative transcriptional regulator (VIMSS) | compare |
| b2683 | ygaH | -1.1 | -3.5 | predicted inner membrane protein (NCBI) | compare |
| b3497 | yhiQ | -1.1 | -7.1 | predicted SAM-dependent methyltransferase (NCBI) | compare |
| b1304 | pspA | -1.1 | -3.8 | regulatory protein for phage-shock-protein operon (NCBI) | compare |
| b1085 | b1085 | -1.1 | -2.6 | orf, hypothetical protein (VIMSS) | compare |
| b0080 | fruR | -1.1 | -4.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2024 | hisA | -1.1 | -2.6 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3261 | fis | -1.1 | -1.6 | DNA-binding protein Fis (NCBI) | compare |
| b3771 | ilvD | -1.1 | -8.5 | dihydroxy-acid dehydratase (NCBI) | compare |
| b3774 | ilvC | -1.1 | -8.5 | ketol-acid reductoisomerase (NCBI) | compare |
| b1831 | proQ | -1.1 | -3.0 | putative solute/DNA competence effector (NCBI) | compare |
| b3706 | trmE | -1.0 | -3.1 | tRNA modification GTPase (NCBI) | compare |
| b0439 | lon | -1.0 | -3.2 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3163 | nlpI | -1.0 | -3.4 | hypothetical protein (NCBI) | compare |
| b2579 | yfiD | -1.0 | -1.8 | pyruvate formate lyase subunit (NCBI) | compare |
| b4179 | vacB | -1.0 | -4.0 | putative enzyme (VIMSS) | compare |
| b2935 | tktA | -1.0 | -1.6 | transketolase 1, thiamin-binding (NCBI) | compare |
| b1689 | b1689 | -1.0 | -2.6 | orf, hypothetical protein (VIMSS) | compare |
| b3289 | rsmB | -1.0 | -7.9 | 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) | compare |
| b1584 | speG | -1.0 | -5.6 | spermidine N1-acetyltransferase (NCBI) | compare |
| b4214 | cysQ | -1.0 | -8.0 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b0113 | pdhR | -1.0 | -5.2 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b1291 | sapD | -1.0 | -1.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4702 | mgtL | -1.0 | -0.9 | regulatory leader peptide for mgtA (NCBI) | compare |
| b4676 | yoaK | -1.0 | -0.5 | expressed protein (RefSeq) | compare |
| b3728 | pstS | -1.0 | -3.0 | phosphate transporter subunit (NCBI) | compare |
| b1871 | yecP | -1.0 | -4.5 | predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) | compare |
| b3842 | rfaH | -1.0 | -3.3 | transcriptional activator RfaH (NCBI) | compare |
| b3465 | yhhF | -1.0 | -4.1 | predicted methyltransferase (NCBI) | compare |
| b2023 | hisH | -1.0 | -5.3 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b4375 | prfC | -1.0 | -3.9 | peptide chain release factor 3 (NCBI) | compare |
| b3162 | deaD | -1.0 | -3.6 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b1593 | b1593 | -1.0 | -4.0 | orf, hypothetical protein (VIMSS) | compare |
| b0101 | yacG | -0.9 | -3.6 | zinc-binding protein (NCBI) | compare |
| b2614 | grpE | -0.9 | -2.4 | heat shock protein (NCBI) | compare |
| b3619 | rfaD | -0.9 | -0.6 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b4146 | yjeK | -0.9 | -1.2 | predicted lysine aminomutase (NCBI) | compare |
| b2295 | yfbV | -0.9 | -5.3 | hypothetical protein (NCBI) | compare |
| b2020 | hisD | -0.9 | -5.7 | histidinol dehydrogenase (NCBI) | compare |
| b3770 | ilvE | -0.9 | -7.1 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b1101 | ptsG | -0.9 | -6.2 | fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) | compare |
| b3260 | dusB | -0.9 | -4.0 | tRNA-dihydrouridine synthase B (NCBI) | compare |
| b0143 | pcnB | -0.9 | -3.9 | poly(A) polymerase I (VIMSS) | compare |
| b3292 | zntR | -0.9 | -3.7 | zinc-responsive transcriptional regulator (NCBI) | compare |
| b2493 | yfgO | -0.9 | -5.4 | predicted inner membrane protein (NCBI) | compare |
| b4203 | rplI | -0.9 | -3.4 | 50S ribosomal protein L9 (NCBI) | compare |
| b2022 | hisB | -0.9 | -4.9 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b3784 | rfe | -0.9 | -5.7 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b4246 | pyrL | -0.9 | -1.1 | pyrBI operon leader peptide (NCBI) | compare |
| b3787 | rffD | -0.9 | -4.9 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b1533 | ydeD | -0.9 | -2.4 | orf, hypothetical protein (VIMSS) | compare |
| b3387 | dam | -0.9 | -4.4 | DNA adenine methylase (NCBI) | compare |
| b1292 | sapC | -0.9 | -1.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3935 | priA | -0.9 | -2.4 | primosome assembly protein PriA (NCBI) | compare |
| b2752 | cysD | -0.9 | -4.9 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b1334 | fnr | -0.9 | -1.9 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |