Experiment set55IT055 for Escherichia coli BW25113

Compare to:

Fr_1000_F3

200 most important genes:

  gene name fitness t score description  
b1480 sra -2.4 -2.4 30S ribosomal subunit protein S22 (NCBI) compare
b4520 ymgF -2.2 -2.4 hypothetical protein (NCBI) compare
b4202 rpsR -2.1 -2.0 30S ribosomal protein S18 (NCBI) compare
b3183 obgE -1.9 -1.9 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3962 udhA -1.8 -8.3 putative oxidoreductase (VIMSS) compare
b3164 pnp -1.7 -3.7 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1572 ydfB -1.7 -2.2 orf, hypothetical protein (VIMSS) compare
b3390 aroK -1.6 -3.1 shikimate kinase I (NCBI) compare
b2330 yfcB -1.5 -2.2 putative adenine-specific methylase (VIMSS) compare
b0407 yajC -1.5 -3.6 preprotein translocase subunit YajC (NCBI) compare
b2528 iscA -1.5 -2.6 iron-sulfur cluster assembly protein (NCBI) compare
b4676 yoaK -1.4 -0.6 expressed protein (RefSeq) compare
b1524 yneH -1.4 -1.2 predicted glutaminase (NCBI) compare
b2699 recA -1.3 -0.9 recombinase A (NCBI) compare
b2363 yfdT -1.3 -2.4 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3979 thrT -1.3 -0.4 tRNA-Thr (NCBI) compare
b1567 intK -1.3 -1.6 Qin prophage; predicted protein (RefSeq) compare
b0858 ybjO -1.2 -3.2 predicted inner membrane protein (NCBI) compare
b2318 truA -1.2 -3.3 tRNA pseudouridine synthase A (NCBI) compare
b3816 corA -1.2 -7.2 magnesium/nickel/cobalt transporter (NCBI) compare
b1557 cspB -1.2 -2.2 Qin prophage; cold shock protein (NCBI) compare
b3916 pfkA -1.2 -2.8 6-phosphofructokinase (NCBI) compare
b4163 glyV -1.2 -1.3 tRNA-Gly (NCBI) compare
b3706 trmE -1.1 -4.6 tRNA modification GTPase (NCBI) compare
b2620 smpB -1.1 -1.3 SsrA-binding protein (NCBI) compare
b1427 rimL -1.1 -3.0 ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) compare
b1563 relE -1.1 -2.1 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1550 b1550 -1.1 -1.7 orf, hypothetical protein (VIMSS) compare
b4041 plsB -1.1 -1.6 glycerol-3-phosphate acyltransferase (VIMSS) compare
b4246 pyrL -1.1 -1.8 pyrBI operon leader peptide (NCBI) compare
b0049 apaH -1.1 -3.0 diadenosinetetraphosphatase (NCBI) compare
b3500 gor -1.1 -1.8 glutathione reductase (NCBI) compare
b3181 greA -1.1 -3.8 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b2498 upp -1.1 -2.5 uracil phosphoribosyltransferase (VIMSS) compare
b4215 ytfI -1.0 -1.5 hypothetical protein (NCBI) compare
b0386 proC -1.0 -3.4 pyrroline-5-carboxylate reductase (NCBI) compare
b1648 b1648 -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b1942 fliJ -1.0 -1.3 flagellar biosynthesis chaperone (NCBI) compare
b1175 minD -1.0 -3.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1612 fumA -1.0 -4.0 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b4320 fimH -1.0 -7.1 minor component of type 1 fimbriae (NCBI) compare
b1730 ydjO -1.0 -1.2 predicted protein (RefSeq) compare
b3781 trxA -1.0 -3.9 thioredoxin 1 (VIMSS) compare
b3613 yibP -1.0 -3.1 putative membrane protein (VIMSS) compare
b1252 tonB -1.0 -2.7 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0471 ybaB -1.0 -2.8 hypothetical protein (NCBI) compare
b1874 cutC -1.0 -1.9 copper homeostasis protein (NCBI) compare
b0142 folK -1.0 -0.6 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1583 ynfB -0.9 -2.1 hypothetical protein (NCBI) compare
b1627 rsxA -0.9 -3.0 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b0232 yafN -0.9 -0.4 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1618 uidR -0.9 -2.0 DNA-binding transcriptional repressor (NCBI) compare
b4316 fimC -0.9 -6.2 periplasmic chaperone, required for type 1 fimbriae (VIMSS) compare
b2319 usg -0.9 -3.4 hypothetical protein (NCBI) compare
b4232 fbp -0.9 -6.0 fructose-1,6-bisphosphatase (NCBI) compare
b3870 glnA -0.9 -2.4 glutamine synthetase (NCBI) compare
b2312 purF -0.9 -4.3 amidophosphoribosyltransferase (NCBI) compare
b3414 gntY -0.9 -3.8 predicted gluconate transport associated protein (NCBI) compare
b0889 lrp -0.9 -2.5 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b3761 trpT -0.9 -1.4 tRNA-Trp (NCBI) compare
b3162 deaD -0.9 -3.7 inducible ATP-independent RNA helicase (VIMSS) compare
b0888 trxB -0.8 -2.3 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4551 yheV -0.8 -2.3 hypothetical protein (NCBI) compare
b4317 fimD -0.8 -7.9 outer membrane usher protein, type 1 fimbrial synthesis (NCBI) compare
b0746 valZ -0.8 -2.1 tRNA-Val (NCBI) compare
b1575 dicB -0.8 -1.0 Qin prophage; cell division inhibition protein (NCBI) compare
b0741 pal -0.8 -2.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b4314 fimA -0.8 -5.4 major type 1 subunit fimbrin (pilin) (NCBI) compare
b1628 rsxB -0.8 -2.2 electron transport complex protein RnfB (NCBI) compare
b0767 ybhE -0.8 -3.1 6-phosphogluconolactonase (NCBI) compare
b3426 glpD -0.8 -2.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b4481 rffT -0.8 -3.8 4-alpha-L-fucosyltransferase (NCBI) compare
b3237 argR -0.8 -3.2 arginine repressor (NCBI) compare
b0564 appY -0.8 -0.6 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3807 cyaY -0.8 -4.7 frataxin-like protein (NCBI) compare
b3791 rffA -0.8 -4.0 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4179 vacB -0.8 -4.2 putative enzyme (VIMSS) compare
b4634 ylcF -0.8 -2.0 no description compare
b3180 yhbY -0.8 -2.7 predicted RNA-binding protein (NCBI) compare
b3794 rffM -0.8 -4.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b0881 clpS -0.8 -1.4 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b4312 fimB -0.8 -5.3 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b0605 ahpC -0.8 -2.2 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b2569 lepA -0.8 -3.1 GTP-binding protein LepA (NCBI) compare
b3239 yhcO -0.7 -1.7 predicted barnase inhibitor (NCBI) compare
b0523 purE -0.7 -1.9 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b1984 asnW -0.7 -0.8 tRNA-Asn (NCBI) compare
b0405 queA -0.7 -4.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b1540 ydfH -0.7 -0.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1355 b1355 -0.7 -2.7 orf, hypothetical protein (VIMSS) compare
b3232 yhcM -0.7 -5.5 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b0051 ksgA -0.7 -2.8 dimethyladenosine transferase (NCBI) compare
b2501 ppk -0.7 -4.3 polyphosphate kinase (NCBI) compare
b2576 srmB -0.7 -2.2 ATP-dependent RNA helicase (NCBI) compare
b3871 bipA -0.7 -5.3 GTP-binding protein (NCBI) compare
b1074 flgC -0.7 -1.8 flagellar basal-body rod protein C (NCBI) compare
b0739 tolA -0.7 -2.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1349 recT -0.7 -3.0 Rac prophage; recombination and repair protein (NCBI) compare
b0052 pdxA -0.7 -4.5 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
b4011 yjaA -0.7 -1.6 hypothetical protein (NCBI) compare
b1686 ydiI -0.7 -1.6 hypothetical protein (NCBI) compare
b2673 nrdH -0.7 -2.6 glutaredoxin-like protein (NCBI) compare
b4319 fimG -0.7 -4.2 minor component of type 1 fimbriae (NCBI) compare
b1269 rluB -0.7 -2.6 23S rRNA pseudouridylate synthase (NCBI) compare
b0738 tolR -0.7 -1.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1562 hokD -0.7 -1.6 Qin prophage; small toxic polypeptide (NCBI) compare
b3101 yqjF -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b1418 cybB -0.7 -1.5 cytochrome b(561) (VIMSS) compare
b1569 dicC -0.7 -2.1 Qin prophage; DNA-binding transcriptional regulator for DicB (NCBI) compare
b3790 rffC -0.7 -3.2 TDP-fucosamine acetyltransferase (RefSeq) compare
b3389 aroB -0.7 -4.6 3-dehydroquinate synthase (NCBI) compare
b0191 yaeJ -0.7 -3.0 hypothetical protein (NCBI) compare
b4005 purD -0.7 -4.5 phosphoribosylamine--glycine ligase (NCBI) compare
b1855 lpxM -0.6 -2.2 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3792 wzxE -0.6 -3.9 O-antigen translocase (NCBI) compare
b3839 tatC -0.6 -3.6 TatABCE protein translocation system subunit (NCBI) compare
b1822 rrmA -0.6 -2.3 23S rRNA m1G745 methyltransferase (NCBI) compare
b4582 yoeA -0.6 -1.6 no description compare
b1642 slyA -0.6 -1.1 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b3787 rffD -0.6 -4.6 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b4409 blr -0.6 -3.1 beta-lactam resistance membrane protein (NCBI) compare
b4453 ldrD -0.6 -1.2 toxic polypeptide, small (NCBI) compare
b1090 plsX -0.6 -2.3 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b3281 aroE -0.6 -5.2 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b2050 wcaI -0.6 -2.4 predicted glycosyl transferase (NCBI) compare
b1121 ycfZ -0.6 -1.1 predicted inner membrane protein (NCBI) compare
b3425 glpE -0.6 -3.0 thiosulfate sulfurtransferase (NCBI) compare
b4006 purH -0.6 -4.7 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b4178 yjeB -0.6 -3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1104 ycfL -0.6 -1.6 hypothetical protein (NCBI) compare
b1128 ycfD -0.6 -3.0 orf, hypothetical protein (VIMSS) compare
b3259 prmA -0.6 -1.8 ribosomal protein L11 methyltransferase (NCBI) compare
b1084 rne -0.6 -2.8 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b2683 ygaH -0.6 -2.1 predicted inner membrane protein (NCBI) compare
b0707 ybgA -0.6 -1.5 hypothetical protein (NCBI) compare
b3225 nanA -0.6 -3.5 N-acetylneuraminate lyase (NCBI) compare
b2500 purN -0.6 -2.5 phosphoribosylglycinamide formyltransferase (NCBI) compare
b0437 clpP -0.6 -3.3 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b1270 btuR -0.6 -2.8 cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) compare
b1144 ymfJ -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b4552 yrhC -0.6 -0.3 no description compare
b0247 ykfG -0.6 -0.9 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1559 b1559 -0.6 -3.1 orf, hypothetical protein (VIMSS) compare
b1063 yceB -0.6 -2.1 predicted lipoprotein (NCBI) compare
b0161 degP -0.6 -3.4 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b3416 malQ -0.6 -4.8 4-alpha-glucanotransferase (amylomaltase) (NCBI) compare
b2446 yffO -0.6 -1.4 CPZ-55 prophage; predicted protein (NCBI) compare
b2419 yfeK -0.6 -0.9 hypothetical protein (NCBI) compare
b0216 aspV -0.6 -3.2 tRNA-Asp (NCBI) compare
b2356 yfdM -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b0624 crcB -0.6 -1.9 camphor resistance protein CrcB (NCBI) compare
b0438 clpX -0.6 -3.3 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3741 gidA -0.6 -1.9 glucose-inhibited division protein A (NCBI) compare
b4545 ypdJ -0.6 -1.2 no description compare
b1279 yciS -0.6 -0.8 conserved inner membrane protein (NCBI) compare
b1693 aroD -0.6 -2.9 3-dehydroquinate dehydratase (NCBI) compare
b2410 yfeH -0.6 -2.0 predicted inner membrane protein (NCBI) compare
b0125 hpt -0.6 -2.8 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b1231 tyrT -0.6 -0.7 tRNA-Tyr (NCBI) compare
b1989 asnV -0.6 -1.3 tRNA-Asn (NCBI) compare
b0338 cynR -0.6 -2.1 DNA-binding transcriptional dual regulator (NCBI) compare
b2947 gshB -0.6 -1.6 glutathione synthetase (NCBI) compare
b2954 yggV -0.6 -2.4 putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) compare
b4269 yjgB -0.6 -2.8 putative oxidoreductase (VIMSS) compare
b0364 yaiS -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b2003 yeeT -0.6 -2.0 CP4-44 prophage; predicted protein (NCBI) compare
b2499 purM -0.6 -2.8 phosphoribosylaminoimidazole synthetase (NCBI) compare
b0004 thrC -0.6 -3.5 threonine synthase (NCBI) compare
b1848 yebG -0.6 -0.9 conserved protein regulated by LexA (NCBI) compare
b2349 intS -0.6 -2.3 CPS-53 (KpLE1) prophage; predicted prophage CPS-53 integrase (NCBI) compare
b1362 rzpR -0.6 -1.2 putative Rac prophage endopeptidase (VIMSS) compare
b2320 pdxB -0.6 -3.6 erythronate-4-phosphate dehydrogenase (NCBI) compare
b0059 hepA -0.6 -4.6 ATP-dependent helicase HepA (NCBI) compare
b1798 yeaS -0.6 -3.1 neutral amino-acid efflux system (NCBI) compare
b2784 relA -0.6 -3.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0632 dacA -0.5 -3.7 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b2476 purC -0.5 -1.6 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b2688 gshA -0.5 -3.2 glutamate--cysteine ligase (NCBI) compare
b4436 ryeC -0.5 -0.6 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b3863 polA -0.5 -0.5 DNA polymerase I (NCBI) compare
b1632 rsxE -0.5 -3.5 NADH-ubiquinone oxidoreductase (NCBI) compare
b4627 ykfL -0.5 -1.5 no description compare
b2214 yojL -0.5 -3.0 predicted thiamine biosynthesis lipoprotein (NCBI) compare
b2689 yqaA -0.5 -1.8 conserved inner membrane protein (NCBI) compare
b3497 yhiQ -0.5 -2.8 predicted SAM-dependent methyltransferase (NCBI) compare
b4402 yjjY -0.5 -0.6 hypothetical protein (NCBI) compare
b1443 ydcV -0.5 -1.3 predicted spermidine/putrescine transporter subunit (NCBI) compare
b4589 ylcI -0.5 -1.0 hypothetical protein (RefSeq) compare
b2830 nudH -0.5 -0.8 dinucleoside polyphosphate hydrolase (NCBI) compare
b0740 tolB -0.5 -2.1 translocation protein TolB precursor (NCBI) compare
b0418 pgpA -0.5 -3.0 phosphatidylglycerophosphatase A (NCBI) compare
b1387 maoC -0.5 -2.9 fused aldehyde dehydrogenase/enoyl-CoA hydratase (NCBI) compare
b2350 yfdG -0.5 -2.9 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b2794 yqcD -0.5 -2.7 hypothetical protein (NCBI) compare
b4503 yafF -0.5 -0.5 no description compare
b1399 paaX -0.5 -1.3 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive (NCBI) compare
b3149 yraO -0.5 -2.7 DnaA initiator-associating factor for replication initiation (NCBI) compare
b0522 purK -0.5 -3.4 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b1542 ydfI -0.5 -1.3 predicted mannonate dehydrogenase (NCBI) compare
b0977 hyaF -0.5 -2.3 protein involved in nickel incorporation into hydrogenase-1 proteins (NCBI) compare


Specific Phenotypes

For 4 genes in this experiment

For fr_1000_f3 Fr_1000_F3 in Escherichia coli BW25113

For fr_1000_f3 Fr_1000_F3 across organisms