Experiment set55IT052 for Escherichia coli BW25113

Compare to:

Fr_1000_E3

200 most important genes:

  gene name fitness t score description  
b3636 rpmG -3.6 -3.8 50S ribosomal protein L33 (NCBI) compare
b3341 rpsG -2.6 -2.3 30S ribosomal protein S7 (NCBI) compare
b1361 ydaW -2.2 -0.9 orf, hypothetical protein (VIMSS) compare
b1231 tyrT -2.0 -2.0 tRNA-Tyr (NCBI) compare
b4593 ymgI -1.9 -1.7 hypothetical protein (RefSeq) compare
b4202 rpsR -1.8 -2.3 30S ribosomal protein S18 (NCBI) compare
b0049 apaH -1.6 -4.0 diadenosinetetraphosphatase (NCBI) compare
b3183 obgE -1.5 -2.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4676 yoaK -1.5 -0.8 expressed protein (RefSeq) compare
b4402 yjjY -1.5 -1.3 hypothetical protein (NCBI) compare
b3390 aroK -1.3 -3.1 shikimate kinase I (NCBI) compare
b3979 thrT -1.3 -0.5 tRNA-Thr (NCBI) compare
b3962 udhA -1.2 -6.1 putative oxidoreductase (VIMSS) compare
b0888 trxB -1.1 -3.6 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3816 corA -1.1 -7.6 magnesium/nickel/cobalt transporter (NCBI) compare
b2935 tktA -1.0 -1.5 transketolase 1, thiamin-binding (NCBI) compare
b0550 rusA -1.0 -2.6 DLP12 prophage; endonuclease RUS (NCBI) compare
b1686 ydiI -1.0 -2.6 hypothetical protein (NCBI) compare
b2528 iscA -1.0 -1.7 iron-sulfur cluster assembly protein (NCBI) compare
b2259 pmrD -1.0 -1.1 polymyxin resistance protein B (VIMSS) compare
b2318 truA -1.0 -2.4 tRNA pseudouridine synthase A (NCBI) compare
b4407 thiS -1.0 -2.3 sulfur carrier protein ThiS (NCBI) compare
b3414 gntY -0.9 -4.1 predicted gluconate transport associated protein (NCBI) compare
b2894 xerD -0.9 -1.1 site-specific tyrosine recombinase XerD (NCBI) compare
b0627 tatE -0.9 -1.7 twin arginine translocase protein E (NCBI) compare
b3162 deaD -0.8 -3.8 inducible ATP-independent RNA helicase (VIMSS) compare
b4435 isrC -0.8 -1.9 unknown RNA (NCBI) compare
b1782 mipA -0.8 -3.6 scaffolding protein for murein synthesizing machinery (NCBI) compare
b1582 ynfA -0.8 -1.7 hypothetical protein (NCBI) compare
b3706 trmE -0.8 -3.4 tRNA modification GTPase (NCBI) compare
b1524 yneH -0.8 -0.9 predicted glutaminase (NCBI) compare
b3032 cpdA -0.8 -5.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b1841 yobA -0.8 -1.7 hypothetical protein (NCBI) compare
b3742 mioC -0.8 -3.8 flavodoxin (NCBI) compare
b1557 cspB -0.8 -2.2 Qin prophage; cold shock protein (NCBI) compare
b1572 ydfB -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b4410 ecnA -0.8 -1.1 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b3839 tatC -0.8 -4.4 TatABCE protein translocation system subunit (NCBI) compare
b1084 rne -0.8 -4.2 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4201 priB -0.8 -2.3 primosomal replication protein N (NCBI) compare
b3181 greA -0.8 -3.6 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0707 ybgA -0.8 -2.3 hypothetical protein (NCBI) compare
b1581 rspA -0.8 -2.0 predicted dehydratase (NCBI) compare
b4179 vacB -0.8 -4.3 putative enzyme (VIMSS) compare
b3916 pfkA -0.7 -2.1 6-phosphofructokinase (NCBI) compare
b4171 miaA -0.7 -2.1 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1863 ruvC -0.7 -1.0 Holliday junction resolvase (NCBI) compare
b2209 eco -0.7 -1.6 ecotin precursor (NCBI) compare
b1618 uidR -0.7 -1.8 DNA-binding transcriptional repressor (NCBI) compare
b0624 crcB -0.7 -3.4 camphor resistance protein CrcB (NCBI) compare
b4203 rplI -0.7 -3.2 50S ribosomal protein L9 (NCBI) compare
b0247 ykfG -0.7 -1.2 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1121 ycfZ -0.7 -1.5 predicted inner membrane protein (NCBI) compare
b1279 yciS -0.7 -1.1 conserved inner membrane protein (NCBI) compare
b3781 trxA -0.7 -3.2 thioredoxin 1 (VIMSS) compare
b1839 yebY -0.7 -2.6 hypothetical protein (NCBI) compare
b1871 yecP -0.7 -3.1 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b1613 manA -0.7 -1.7 mannose-6-phosphate isomerase (VIMSS) compare
b0858 ybjO -0.7 -2.0 predicted inner membrane protein (NCBI) compare
b4042 dgkA -0.7 -1.4 diacylglycerol kinase (NCBI) compare
b0386 proC -0.7 -3.0 pyrroline-5-carboxylate reductase (NCBI) compare
b0346 mhpR -0.7 -2.2 DNA-binding transcriptional activator, 3HPP-binding (RefSeq) compare
b0740 tolB -0.7 -2.4 translocation protein TolB precursor (NCBI) compare
b0560 nohB -0.7 -1.5 DLP12 prophage; DNA packaging protein (NCBI) compare
b1358 ydaT -0.6 -0.6 Rac prophage; predicted protein (NCBI) compare
b1107 nagZ -0.6 -3.1 beta-hexosaminidase (NCBI) compare
b1726 yniB -0.6 -1.8 predicted inner membrane protein (NCBI) compare
b2804 fucU -0.6 -1.4 L-fucose mutarotase (NCBI) compare
b1855 lpxM -0.6 -3.3 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1175 minD -0.6 -3.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2376 ypdI -0.6 -2.1 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b2910 zapA -0.6 -2.1 protein that localizes to the cytokinetic ring (NCBI) compare
b1551 b1551 -0.6 -0.4 orf, hypothetical protein (VIMSS) compare
b4520 ymgF -0.6 -1.1 hypothetical protein (NCBI) compare
b1506 yneL -0.6 -0.8 predicted transcriptional regulator (NCBI) compare
b3237 argR -0.6 -2.6 arginine repressor (NCBI) compare
b0053 surA -0.6 -3.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1074 flgC -0.6 -1.4 flagellar basal-body rod protein C (NCBI) compare
b4504 ykfH -0.6 -1.8 hypothetical protein (NCBI) compare
b0127 yadG -0.6 -3.0 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b2636 b2636 -0.6 -2.9 orf, hypothetical protein (VIMSS) compare
b0849 grxA -0.6 -1.8 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b2198 ccmD -0.6 -2.0 cytochrome c biogenesis protein (NCBI) compare
b3426 glpD -0.6 -1.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0295 ykgL -0.6 -3.3 hypothetical protein (NCBI) compare
b2620 smpB -0.6 -0.9 SsrA-binding protein (NCBI) compare
b2143 cdd -0.6 -1.8 cytidine deaminase (NCBI) compare
b2823 ppdC -0.6 -2.1 hypothetical protein (NCBI) compare
b4215 ytfI -0.6 -1.1 hypothetical protein (NCBI) compare
b2025 hisF -0.6 -2.2 imidazole glycerol phosphate synthase subunit HisF (NCBI) compare
b0937 ssuE -0.6 -1.5 NAD(P)H-dependent FMN reductase (NCBI) compare
b1961 dcm -0.5 -0.8 DNA cytosine methylase (NCBI) compare
b0890 ftsK -0.5 -2.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1540 ydfH -0.5 -0.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b3617 kbl -0.5 -3.3 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b3973 birA -0.5 -1.8 biotin--protein ligase (NCBI) compare
b3497 yhiQ -0.5 -3.4 predicted SAM-dependent methyltransferase (NCBI) compare
b1144 ymfJ -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b1567 intK -0.5 -1.4 Qin prophage; predicted protein (RefSeq) compare
b2058 wcaB -0.5 -0.7 predicted acyl transferase (NCBI) compare
b0339 cynT -0.5 -2.1 carbonic anhydrase (NCBI) compare
b0122 yacC -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b0977 hyaF -0.5 -1.9 protein involved in nickel incorporation into hydrogenase-1 proteins (NCBI) compare
b1575 dicB -0.5 -0.7 Qin prophage; cell division inhibition protein (NCBI) compare
b0998 torD -0.5 -0.6 chaperone protein TorD (NCBI) compare
b1627 rsxA -0.5 -1.2 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b2258 b2258 -0.5 -0.7 putative transport/receptor protein (VIMSS) compare
b0556 rzpD -0.5 -2.1 DLP12 prophage; predicted murein endopeptidase (NCBI) compare
b1926 fliT -0.5 -2.2 predicted chaperone (NCBI) compare
b2678 proW -0.5 -2.8 glycine betaine transporter subunit (NCBI) compare
b4644 ypjI -0.5 -2.3 no description compare
b2642 yfjW -0.5 -0.5 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2646 ypjF -0.5 -1.7 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b4341 yjiS -0.5 -2.4 hypothetical protein (NCBI) compare
b1259 yciG -0.5 -1.0 orf, hypothetical protein (VIMSS) compare
b0555 ybcS -0.5 -3.1 DLP12 prophage; predicted lysozyme (NCBI) compare
b2199 ccmC -0.5 -1.9 heme exporter subunit (NCBI) compare
b1550 b1550 -0.5 -1.0 orf, hypothetical protein (VIMSS) compare
b3427 yzgL -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b1530 marR -0.5 -1.9 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b1814 sdaA -0.5 -1.6 L-serine deaminase I (NCBI) compare
b2501 ppk -0.5 -3.2 polyphosphate kinase (NCBI) compare
b4654 yjdQ -0.5 -2.5 no description compare
b0921 smtA -0.5 -3.1 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b4227 ytfQ -0.5 -2.1 predicted sugar transporter subunit: periplasmic-binding component of ABC superfamily (NCBI) compare
b1079 flgH -0.5 -1.6 flagellar L-ring protein precursor H (NCBI) compare
b1351 racC -0.5 -0.3 Rac prophage; predicted protein (NCBI) compare
b1199 dhaL -0.5 -1.6 dihydroxyacetone kinase, C-terminal domain (NCBI) compare
b2897 ygfY -0.5 -1.7 hypothetical protein (NCBI) compare
b4431 rprA -0.5 -0.9 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b1159 mcrA -0.5 -0.6 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b0523 purE -0.5 -1.4 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b4511 ybdZ -0.5 -1.0 hypothetical protein (NCBI) compare
b1628 rsxB -0.5 -1.7 electron transport complex protein RnfB (NCBI) compare
b0746 valZ -0.5 -1.4 tRNA-Val (NCBI) compare
b1252 tonB -0.5 -1.7 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3126 garL -0.5 -2.1 alpha-dehydro-beta-deoxy-D-glucarate aldolase (NCBI) compare
b0503 ybbB -0.5 -1.8 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b4232 fbp -0.5 -3.7 fructose-1,6-bisphosphatase (NCBI) compare
b1176 minC -0.5 -1.4 septum formation inhibitor (NCBI) compare
b3838 tatB -0.5 -2.6 sec-independent translocase (NCBI) compare
b4414 tff -0.5 -1.6 unknown RNA (NCBI) compare
b1682 sufC -0.5 -1.9 cysteine desulfurase ATPase component (NCBI) compare
b1562 hokD -0.5 -1.3 Qin prophage; small toxic polypeptide (NCBI) compare
b0131 panD -0.5 -1.5 aspartate 1-decarboxylase precursor (NCBI) compare
b1560 ydfU -0.5 -1.8 Qin prophage; predicted protein (RefSeq) compare
b3149 yraO -0.4 -2.5 DnaA initiator-associating factor for replication initiation (NCBI) compare
b2297 pta -0.4 -0.3 phosphate acetyltransferase (NCBI) compare
b2375 yfdX -0.4 -1.6 hypothetical protein (NCBI) compare
b2614 grpE -0.4 -1.2 heat shock protein (NCBI) compare
b0753 ybgS -0.4 -2.2 hypothetical protein (NCBI) compare
b0767 ybhE -0.4 -1.4 6-phosphogluconolactonase (NCBI) compare
b3812 yigB -0.4 -2.7 predicted hydrolase (NCBI) compare
b2204 napH -0.4 -1.7 quinol dehydrogenase membrane component (NCBI) compare
b4634 ylcF -0.4 -1.4 no description compare
b2688 gshA -0.4 -2.7 glutamate--cysteine ligase (NCBI) compare
b4702 mgtL -0.4 -0.9 regulatory leader peptide for mgtA (NCBI) compare
b3871 bipA -0.4 -3.3 GTP-binding protein (NCBI) compare
b2948 yqgE -0.4 -1.7 orf, hypothetical protein (VIMSS) compare
b2951 yggS -0.4 -2.3 predicted enzyme (NCBI) compare
b2136 yohD -0.4 -1.1 orf, hypothetical protein (VIMSS) compare
b0008 talB -0.4 -2.7 transaldolase B (NCBI) compare
b1606 folM -0.4 -2.3 short chain dehydrogenase (NCBI) compare
b0340 cynS -0.4 -1.0 cyanate hydratase (NCBI) compare
b2435 amiA -0.4 -2.0 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b4620 yjbT -0.4 -1.8 hypothetical protein, no homologs (RefSeq) compare
b3858 yihD -0.4 -1.4 hypothetical protein (NCBI) compare
b0630 lipB -0.4 -0.4 protein of lipoate biosynthesis (VIMSS) compare
b4158 yjeO -0.4 -1.2 conserved inner membrane protein (NCBI) compare
b3761 trpT -0.4 -0.8 tRNA-Trp (NCBI) compare
b1746 astD -0.4 -2.3 succinylglutamic semialdehyde dehydrogenase (NCBI) compare
b0605 ahpC -0.4 -1.2 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b2830 nudH -0.4 -0.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b2354 yfdK -0.4 -2.2 CPS-53 (KpLE1) prophage; conserved protein (NCBI) compare
b2683 ygaH -0.4 -2.4 predicted inner membrane protein (NCBI) compare
b0739 tolA -0.4 -1.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1917 yecC -0.4 -1.3 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4314 fimA -0.4 -2.4 major type 1 subunit fimbrin (pilin) (NCBI) compare
b2576 srmB -0.4 -1.2 ATP-dependent RNA helicase (NCBI) compare
b1516 lsrB -0.4 -1.8 AI2 transporter (NCBI) compare
b3035 tolC -0.4 -2.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b4481 rffT -0.4 -2.2 4-alpha-L-fucosyltransferase (NCBI) compare
b0738 tolR -0.4 -1.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4441 glmY -0.4 -0.8 sRNA activator of glmS mRNA (RefSeq) compare
b4411 ecnB -0.4 -1.9 entericidin B membrane lipoprotein (NCBI) compare
b1481 b1481 -0.4 -1.9 orf, hypothetical protein (VIMSS) compare
b0052 pdxA -0.4 -2.4 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
b1790 yeaM -0.4 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b1692 ydiB -0.4 -1.3 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b1126 potA -0.4 -2.2 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b3792 wzxE -0.4 -2.5 O-antigen translocase (NCBI) compare
b1785 yeaI -0.4 -1.1 predicted diguanylate cyclase (NCBI) compare
b2205 napG -0.4 -2.4 quinol dehydrogenase periplasmic component (NCBI) compare
b4546 ypeB -0.4 -0.5 hypothetical protein (NCBI) compare
b0706 ybfD -0.4 -1.1 hypothetical protein (NCBI) compare
b1128 ycfD -0.4 -2.7 orf, hypothetical protein (VIMSS) compare
b1630 rsxD -0.4 -2.0 electron transport complex protein RnfD (NCBI) compare
b1822 rrmA -0.4 -1.7 23S rRNA m1G745 methyltransferase (NCBI) compare
b1984 asnW -0.4 -0.5 tRNA-Asn (NCBI) compare
b1106 ycfN -0.4 -1.6 thiamin kinase (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For fr_1000_e3 Fr_1000_E3 in Escherichia coli BW25113

For fr_1000_e3 Fr_1000_E3 across organisms