| Pathway | #Steps | #Present | #Specific |
|---|
| glutathionylspermidine biosynthesis | 1 | 1 | 1 |
| siroheme biosynthesis | 4 | 4 | 2 |
| ribose phosphorylation | 2 | 2 | 1 |
| polyphosphate metabolism | 2 | 2 | 1 |
| pseudouridine degradation | 2 | 2 | 1 |
| L-aspartate degradation II (aerobic) | 3 | 3 | 1 |
| 2-deoxy-D-ribose degradation I | 3 | 3 | 1 |
| NAD salvage pathway III (to nicotinamide riboside) | 3 | 3 | 1 |
| L-aspartate degradation III (anaerobic) | 3 | 3 | 1 |
| NAD salvage pathway I (PNC VI cycle) | 7 | 5 | 2 |
| factor 430 biosynthesis | 7 | 3 | 2 |
| dTDP-N-acetylthomosamine biosynthesis | 4 | 4 | 1 |
| heme b biosynthesis I (aerobic) | 4 | 4 | 1 |
| heme b biosynthesis V (aerobic) | 4 | 4 | 1 |
| dTDP-6-deoxy-α-D-allose biosynthesis | 4 | 2 | 1 |
| dTDP-N-acetylviosamine biosynthesis | 4 | 2 | 1 |
| dTDP-β-D-fucofuranose biosynthesis | 4 | 2 | 1 |
| dTDP-β-L-rhamnose biosynthesis | 5 | 5 | 1 |
| NAD salvage pathway II (PNC IV cycle) | 5 | 4 | 1 |
| dTDP-4-O-demethyl-β-L-noviose biosynthesis | 5 | 3 | 1 |
| NAD salvage pathway V (PNC V cycle) | 5 | 3 | 1 |
| dTDP-3-acetamido-α-D-fucose biosynthesis | 5 | 2 | 1 |
| dTDP-3-acetamido-3,6-dideoxy-α-D-glucose biosynthesis | 5 | 2 | 1 |
| dTDP-α-D-mycaminose biosynthesis | 5 | 2 | 1 |
| NAD salvage (plants) | 11 | 5 | 2 |
| superpathway of heme b biosynthesis from uroporphyrinogen-III | 6 | 6 | 1 |
| ppGpp metabolism | 6 | 6 | 1 |
| TCA cycle VIII (Chlamydia) | 6 | 5 | 1 |
| dTDP-sibirosamine biosynthesis | 6 | 3 | 1 |
| dTDP-L-daunosamine biosynthesis | 6 | 3 | 1 |
| dTDP-α-D-ravidosamine and dTDP-4-acetyl-α-D-ravidosamine biosynthesis | 6 | 2 | 1 |
| dTDP-D-desosamine biosynthesis | 6 | 2 | 1 |
| cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation) | 13 | 2 | 2 |
| superpathway of glyoxylate cycle and fatty acid degradation | 14 | 11 | 2 |
| incomplete reductive TCA cycle | 7 | 5 | 1 |
| pyruvate fermentation to propanoate I | 7 | 5 | 1 |
| dTDP-β-L-olivose biosynthesis | 7 | 3 | 1 |
| dTDP-β-L-digitoxose biosynthesis | 7 | 3 | 1 |
| dTDP-β-L-mycarose biosynthesis | 7 | 2 | 1 |
| cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion) | 15 | 3 | 2 |
| partial TCA cycle (obligate autotrophs) | 8 | 7 | 1 |
| superpathway of heme b biosynthesis from glycine | 8 | 7 | 1 |
| dTDP-β-L-megosamine biosynthesis | 8 | 3 | 1 |
| dTDP-β-L-4-epi-vancosamine biosynthesis | 8 | 3 | 1 |
| TCA cycle V (2-oxoglutarate synthase) | 9 | 7 | 1 |
| TCA cycle VI (Helicobacter) | 9 | 7 | 1 |
| TCA cycle II (plants and fungi) | 9 | 7 | 1 |
| TCA cycle IV (2-oxoglutarate decarboxylase) | 9 | 7 | 1 |
| TCA cycle VII (acetate-producers) | 9 | 6 | 1 |
| 3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent) | 9 | 3 | 1 |
| dTDP-α-D-olivose, dTDP-α-D-oliose and dTDP-α-D-mycarose biosynthesis | 9 | 3 | 1 |
| dTDP-α-D-forosamine biosynthesis | 9 | 3 | 1 |
| 3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) | 9 | 3 | 1 |
| superpathway of heme b biosynthesis from glutamate | 10 | 10 | 1 |
| lipid A-core biosynthesis (E. coli K-12) | 10 | 9 | 1 |
| TCA cycle I (prokaryotic) | 10 | 9 | 1 |
| superpathway of enterobacterial common antigen biosynthesis | 10 | 9 | 1 |
| TCA cycle III (animals) | 10 | 8 | 1 |
| anaerobic energy metabolism (invertebrates, mitochondrial) | 10 | 7 | 1 |
| O-antigen building blocks biosynthesis (E. coli) | 11 | 11 | 1 |
| reductive TCA cycle I | 11 | 8 | 1 |
| L-glutamate degradation VIII (to propanoate) | 11 | 5 | 1 |
| superpathway of glyoxylate bypass and TCA | 12 | 11 | 1 |
| reductive TCA cycle II | 12 | 8 | 1 |
| gluconeogenesis I | 13 | 13 | 1 |
| (S)-lactate fermentation to propanoate, acetate and hydrogen | 13 | 10 | 1 |
| C4 photosynthetic carbon assimilation cycle, PEPCK type | 14 | 9 | 1 |
| superpathway of NAD biosynthesis in eukaryotes | 14 | 7 | 1 |
| mixed acid fermentation | 16 | 16 | 1 |
| adenosylcobalamin biosynthesis II (aerobic) | 33 | 17 | 2 |
| superpathway of anaerobic energy metabolism (invertebrates) | 17 | 12 | 1 |
| adenosylcobalamin biosynthesis I (anaerobic) | 36 | 16 | 2 |
| methylaspartate cycle | 19 | 9 | 1 |
| superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis | 19 | 7 | 1 |
| superpathway of novobiocin biosynthesis | 19 | 4 | 1 |
| superpathway of erythromycin biosynthesis | 19 | 2 | 1 |
| superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle | 22 | 18 | 1 |
| superpathway of megalomicin A biosynthesis | 22 | 3 | 1 |
| superpathway of dTDP-glucose-derived antibiotic building blocks biosynthesis | 23 | 3 | 1 |
| superpathway of Kdo2-lipid A biosynthesis | 25 | 24 | 1 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 26 | 25 | 1 |
| superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis | 33 | 14 | 1 |
| Methanobacterium thermoautotrophicum biosynthetic metabolism | 56 | 22 | 1 |