Experiment set53IT083 for Escherichia coli BW25113

Compare to:

diversity test of Keio_ML9a_ucsf

200 most important genes:

  gene name fitness t score description  
b1361 ydaW -2.7 -1.3 orf, hypothetical protein (VIMSS) compare
b2259 pmrD -0.9 -1.6 polymyxin resistance protein B (VIMSS) compare
b2446 yffO -0.9 -2.6 CPZ-55 prophage; predicted protein (NCBI) compare
b0990 cspG -0.8 -0.9 DNA-binding transcriptional regulator (NCBI) compare
b4451 ryhB -0.8 -1.6 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b2258 b2258 -0.8 -1.5 putative transport/receptor protein (VIMSS) compare
b1724 ydiZ -0.8 -1.7 hypothetical protein (NCBI) compare
b2597 yfiA -0.7 -2.1 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b1551 b1551 -0.7 -0.5 orf, hypothetical protein (VIMSS) compare
b0627 tatE -0.7 -1.7 twin arginine translocase protein E (NCBI) compare
b2642 yfjW -0.7 -0.9 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1273 yciN -0.6 -1.6 hypothetical protein (NCBI) compare
b4570 lomR -0.6 -1.8 no description compare
b1368 ynaA -0.6 -2.3 Rac prophage; predicted tail protein (RefSeq) compare
b4535 yniD -0.6 -1.0 predicted protein (RefSeq) compare
b2071 yegJ -0.6 -1.4 hypothetical protein (NCBI) compare
b2698 recX -0.5 -1.7 RecA regulator RecX (NCBI) compare
b0836 yliH -0.5 -2.1 hypothetical protein (NCBI) compare
b2082 ogrK -0.5 -1.0 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b1727 yniC -0.5 -1.4 predicted hydrolase (NCBI) compare
b1563 relE -0.5 -1.8 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1685 ydiH -0.5 -1.2 predicted protein (RefSeq) compare
b2618 b2618 -0.5 -2.5 orf, hypothetical protein (VIMSS) compare
b1842 holE -0.5 -1.6 DNA polymerase III, theta subunit (NCBI) compare
b4675 yoaJ -0.5 -2.4 expressed protein (RefSeq) compare
b1058 yceO -0.5 -0.3 hypothetical protein (NCBI) compare
b1524 yneH -0.4 -0.7 predicted glutaminase (NCBI) compare
b0850 ybjC -0.4 -2.3 predicted inner membrane protein (NCBI) compare
b4568 ytjA -0.4 -1.4 predicted protein (RefSeq) compare
b1811 yoaH -0.4 -1.6 hypothetical protein (NCBI) compare
b1640 ydhH -0.4 -2.0 anhydro-N-acetylmuramic acid kinase (NCBI) compare
b3199 yrbK -0.4 -1.5 hypothetical protein (NCBI) compare
b1684 sufA -0.4 -1.6 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b3916 pfkA -0.4 -1.5 6-phosphofructokinase (NCBI) compare
b2853 ygeI -0.4 -0.3 hypothetical protein (NCBI) compare
b2352 yfdI -0.4 -0.5 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b2237 inaA -0.4 -1.6 hypothetical protein (NCBI) compare
b0934 ycbM -0.4 -1.0 putative transport system permease protein (VIMSS) compare
b1567 intK -0.4 -1.6 Qin prophage; predicted protein (RefSeq) compare
b2343 b2343 -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b4458 oxyS -0.4 -0.9 global regulatory RNA (NCBI) compare
b4494 arpB -0.4 -1.1 no description compare
b1908 yecA -0.4 -2.5 conserved metal-binding protein (NCBI) compare
b1493 gadB -0.4 -0.6 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1882 cheY -0.4 -0.4 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1266 yciV -0.4 -2.2 hypothetical protein (NCBI) compare
b0081 mraZ -0.4 -2.6 hypothetical protein (NCBI) compare
b1883 cheB -0.4 -2.6 chemotaxis-specific methylesterase (NCBI) compare
b2248 yfaX -0.4 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4655 ythA -0.4 -0.9 expressed protein (RefSeq) compare
b4630 ykgP -0.4 -1.2 no description compare
b1609 rstB -0.4 -2.0 sensory histidine kinase in two-component regulatory system with RstA (NCBI) compare
b4416 rybA -0.4 -0.9 unknown RNA (NCBI) compare
b0787 ybhM -0.4 -1.9 conserved inner membrane protein (NCBI) compare
b2646 ypjF -0.4 -1.7 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b1025 ycdT -0.4 -0.9 predicted diguanylate cyclase (NCBI) compare
b0495 ybbA -0.4 -1.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4363 yjjB -0.4 -2.1 conserved inner membrane protein (RefSeq) compare
b1566 flxA -0.4 -1.6 Qin prophage; predicted protein (NCBI) compare
b2110 yehC -0.4 -0.6 predicted periplasmic pilin chaperone (NCBI) compare
b2144 sanA -0.4 -3.2 hypothetical protein (NCBI) compare
b2809 b2809 -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b2650 ypjC -0.4 -0.2 hypothetical protein (RefSeq) compare
b4135 yjdC -0.4 -2.6 orf, hypothetical protein (VIMSS) compare
b1134 ymfB -0.4 -1.0 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase (NCBI) compare
b2362 yfdS -0.4 -1.5 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1633 nth -0.4 -1.6 DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) (NCBI) compare
b1359 ydaU -0.4 -1.5 Rac prophage; conserved protein (NCBI) compare
b1171 b1171 -0.4 -1.1 orf, hypothetical protein (VIMSS) compare
b1914 uvrY -0.4 -2.2 response regulator (NCBI) compare
b1692 ydiB -0.3 -1.5 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b1796 yoaG -0.3 -2.2 hypothetical protein (NCBI) compare
b0643 ybeL -0.3 -2.3 hypothetical protein (NCBI) compare
b3280 yrdB -0.3 -2.0 hypothetical protein (NCBI) compare
b1148 ymfM -0.3 -1.5 e14 prophage; predicted protein (NCBI) compare
b4646 yrdE -0.3 -1.7 no description compare
b1325 ycjG -0.3 -1.7 putative muconate cycloisomerase I (EC 5.5.-.-) (VIMSS) compare
b3100 yqjK -0.3 -1.7 hypothetical protein (NCBI) compare
b0830 yliB -0.3 -2.7 predicted peptide transporter subunit: periplasmic-binding component of ABC superfamily (NCBI) compare
b0580 ybdJ -0.3 -1.1 predicted inner membrane protein (NCBI) compare
b1513 lsrA -0.3 -1.7 fused AI2 transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4522 yciX_1 -0.3 -0.9 hypothetical protein (NCBI) compare
b1793 yoaF -0.3 -1.6 conserved outer membrane protein (NCBI) compare
b1450 b1450 -0.3 -2.0 orf, hypothetical protein (VIMSS) compare
b4255 yjgD -0.3 -1.5 hypothetical protein (NCBI) compare
b1177 ycgJ -0.3 -1.9 hypothetical protein (NCBI) compare
b1593 b1593 -0.3 -1.1 orf, hypothetical protein (VIMSS) compare
b2291 yfbR -0.3 -1.7 hypothetical protein (NCBI) compare
b0453 ybaY -0.3 -2.4 glycoprotein/polysaccharide metabolism (VIMSS) compare
b1951 rcsA -0.3 -0.6 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b4408 csrB -0.3 -1.4 CsrA-binding sRNA, antagonizing CsrA regulation (NCBI) compare
b4513 kdpF -0.3 -1.2 potassium ion accessory transporter subunit (NCBI) compare
b4493 gapC -0.3 -1.4 no description compare
b2019 hisG -0.3 -2.3 ATP phosphoribosyltransferase (NCBI) compare
b3973 birA -0.3 -1.1 biotin--protein ligase (NCBI) compare
b1429 tehA -0.3 -0.6 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b0326 yahL -0.3 -0.8 hypothetical protein (NCBI) compare
b2078 baeS -0.3 -2.0 sensory histidine kinase in two-component regulatory system with BaeR (NCBI) compare
b1182 hlyE -0.3 -0.2 hemolysin E (VIMSS) compare
b0226 dinJ -0.3 -1.6 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b2123 yehR -0.3 -1.9 orf, hypothetical protein (VIMSS) compare
b0001 thrL -0.3 -0.9 thr operon leader peptide (NCBI) compare
b4573 insZ -0.3 -1.7 no description compare
b0862 artQ -0.3 -1.4 arginine transporter subunit (NCBI) compare
b4609 ryfD -0.3 -1.7 Novel sRNA, function unknown (RefSeq) compare
b0660 ybeZ -0.3 -1.9 predicted protein with nucleoside triphosphate hydrolase domain (RefSeq) compare
b1217 chaB -0.3 -0.9 cation transport regulator (NCBI) compare
b0147 yadP -0.3 -2.3 orf, hypothetical protein (VIMSS) compare
b1868 yecE -0.3 -1.7 hypothetical protein (NCBI) compare
b1328 ycjZ -0.3 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b2435 amiA -0.3 -2.0 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b0435 bolA -0.3 -1.7 possible regulator of murein genes (VIMSS) compare
b0157 yadS -0.3 -1.7 conserved inner membrane protein (NCBI) compare
b1858 znuC -0.3 -2.0 high-affinity zinc transporter ATPase (NCBI) compare
b0726 sucA -0.3 -1.4 alpha-ketoglutarate decarboxylase (NCBI) compare
b4543 ypaA -0.3 -1.0 predicted protein (NCBI) compare
b1121 ycfZ -0.3 -0.7 predicted inner membrane protein (NCBI) compare
b4523 yciX -0.3 -1.4 hypothetical protein (RefSeq) compare
b0977 hyaF -0.3 -1.8 protein involved in nickel incorporation into hydrogenase-1 proteins (NCBI) compare
b3934 cytR -0.3 -2.3 DNA-binding transcriptional dual regulator (NCBI) compare
b0817 mntR -0.3 -1.6 DNA-binding transcriptional regulator of mntH (NCBI) compare
b3961 oxyR -0.3 -2.1 DNA-binding transcriptional dual regulator (NCBI) compare
b0097 yacA -0.3 -1.3 orf, hypothetical protein (VIMSS) compare
b4641 yoeH -0.3 -1.7 no description compare
b4484 cpxP -0.3 -1.9 periplasmic protein combats stress (NCBI) compare
b1581 rspA -0.3 -1.3 predicted dehydratase (NCBI) compare
b2438 b2438 -0.3 -1.7 orf, hypothetical protein (VIMSS) compare
b3761 trpT -0.3 -0.7 tRNA-Trp (NCBI) compare
b4544 yfbW -0.3 -1.2 hypothetical protein (NCBI) compare
b2434 b2434 -0.3 -1.6 orf, hypothetical protein (VIMSS) compare
b2342 yfcY -0.3 -2.1 acetyl-CoA acetyltransferase (NCBI) compare
b2540 hcaC -0.3 -1.2 3-phenylpropionate dioxygenase, predicted ferredoxin subunit (NCBI) compare
b4001 yjaH -0.3 -1.7 hypothetical protein (NCBI) compare
b2125 yehT -0.3 -1.7 orf, hypothetical protein (VIMSS) compare
b2473 ypfH -0.3 -1.9 orf, hypothetical protein (VIMSS) compare
b2266 elaB -0.3 -0.8 hypothetical protein (NCBI) compare
b4068 yjcH -0.3 -1.2 required for glycolate transport, with actP (from data) compare
b1063 yceB -0.3 -1.4 predicted lipoprotein (NCBI) compare
b1523 yneG -0.3 -0.9 hypothetical protein (NCBI) compare
b1752 ydjZ -0.3 -1.0 conserved inner membrane protein (NCBI) compare
b2916 argP -0.3 -1.8 chromosome replication initiation inhibitor protein (NCBI) compare
b0652 gltL -0.3 -1.4 glutamate and aspartate transporter subunit (NCBI) compare
b1499 ydeO -0.3 -0.1 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1000 cbpA -0.3 -1.3 curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK (NCBI) compare
b3188 sfsB -0.3 -1.7 DNA-binding transcriptional activator of maltose metabolism (NCBI) compare
b4456 ryiA -0.3 -1.8 regulatory sRNA (NCBI) compare
b1422 ydcI -0.3 -1.4 putative transcriptional regulator LYSR-type (VIMSS) compare
b2495 yfgD -0.3 -1.4 predicted oxidoreductase (NCBI) compare
b3742 mioC -0.3 -1.2 flavodoxin (NCBI) compare
b3156 yhbS -0.3 -2.0 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b1308 pspE -0.3 -1.3 thiosulfate:cyanide sulfurtransferase (rhodanese) (NCBI) compare
b2666 yqaE -0.3 -1.5 predicted membrane protein (NCBI) compare
b0381 ddlA -0.3 -1.6 D-alanylalanine synthetase (NCBI) compare
b1952 dsrB -0.3 -1.8 hypothetical protein (NCBI) compare
b1953 b1953 -0.3 -1.3 orf, hypothetical protein (VIMSS) compare
b1332 ynaJ -0.3 -0.3 predicted inner membrane protein (NCBI) compare
b1434 ydcN -0.3 -0.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3119 tdcR -0.3 -0.8 threonine dehydratase operon activator protein (VIMSS) compare
b0857 potI -0.3 -1.5 putrescine transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0270 yagG -0.2 -1.8 CP4-6 prophage; predicted sugar transporter (NCBI) compare
b2624 alpA -0.2 -1.7 CP4-57 prophage; DNA-binding transcriptional activator (NCBI) compare
b1114 mfd -0.2 -1.8 transcription-repair coupling factor (NCBI) compare
b1918 yecS -0.2 -0.9 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0840 deoR -0.2 -1.2 DNA-binding transcriptional repressor (NCBI) compare
b1877 yecT -0.2 -0.8 orf, hypothetical protein (VIMSS) compare
b3341 rpsG -0.2 -0.5 30S ribosomal protein S7 (NCBI) compare
b0981 yccC -0.2 -1.7 cryptic autophosphorylating protein tyrosine kinase Etk (NCBI) compare
b1691 ydiN -0.2 -1.1 predicted transporter (RefSeq) compare
b0746 valZ -0.2 -0.9 tRNA-Val (NCBI) compare
b1939 fliG -0.2 -1.4 flagellar motor switch protein G (NCBI) compare
b4508 peaD -0.2 -1.2 putative sensory transduction regulator (VIMSS) compare
b1296 ycjJ -0.2 -0.9 putative amino acid/amine transport protein (VIMSS) compare
b2722 hycD -0.2 -1.8 hydrogenase 3, membrane subunit (NCBI) compare
b1231 tyrT -0.2 -0.4 tRNA-Tyr (NCBI) compare
b4118 melR -0.2 -1.6 DNA-binding transcriptional dual regulator (NCBI) compare
b0191 yaeJ -0.2 -1.5 hypothetical protein (NCBI) compare
b0398 sbcD -0.2 -1.6 exonuclease, dsDNA, ATP-dependent (NCBI) compare
b3764 yifE -0.2 -1.2 hypothetical protein (NCBI) compare
b0764 modB -0.2 -1.6 molybdate ABC transporter permease protein (NCBI) compare
b1651 gloA -0.2 -0.7 glyoxalase I, Ni-dependent (NCBI) compare
b0355 frmB -0.2 -1.7 predicted esterase (NCBI) compare
b2571 rseB -0.2 -1.6 periplasmic negative regulator of sigmaE (NCBI) compare
b1187 fadR -0.2 -1.5 fatty acid metabolism regulator (NCBI) compare
b1526 yneJ -0.2 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0818 ybiR -0.2 -1.8 predicted transporter (NCBI) compare
b2454 eutJ -0.2 -1.6 predicted chaperonin, ethanolamine utilization protein (NCBI) compare
b3125 garR -0.2 -1.4 tartronate semialdehyde reductase (RefSeq) compare
b0042 fixB -0.2 -1.7 predicted electron transfer flavoprotein, NAD/FAD-binding domain and ETFP adenine nucleotide-binding domain-like (NCBI) compare
b0686 ybfF -0.2 -1.6 hypothetical protein (NCBI) compare
b2096 gatY -0.2 -1.2 tagatose-bisphosphate aldolase 1 (VIMSS) compare
b4454 rdlD -0.2 -1.2 sRNA antisense regulator affects LdrD translation; proposed addiction module in LDR-D repeat, with toxic peptide LdrD (RefSeq) compare
b0082 mraW -0.2 -1.0 S-adenosyl-methyltransferase (NCBI) compare
b2236 yfaE -0.2 -0.7 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b4561 insM -0.2 -1.2 transposase (RefSeq) compare
b2752 cysD -0.2 -1.2 sulfate adenylyltransferase subunit 2 (NCBI) compare
b0440 hupB -0.2 -1.5 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b1783 yeaG -0.2 -1.8 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b2494 yfgC -0.2 -1.9 predicted peptidase (NCBI) compare
b4353 yjiX -0.2 -1.5 hypothetical protein (NCBI) compare
b1710 btuE -0.2 -1.2 predicted glutathione peroxidase (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment