| | gene | name | fitness | t score | description | |
|---|
| b0928 | aspC | -5.0 | -10.9 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b3956 | ppc | -4.8 | -26.0 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2838 | lysA | -4.7 | -18.7 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0004 | thrC | -4.7 | -12.9 | threonine synthase (NCBI) | compare |
| b0003 | thrB | -4.7 | -10.7 | homoserine kinase (NCBI) | compare |
| b0907 | serC | -4.7 | -9.9 | phosphoserine aminotransferase (NCBI) | compare |
| b2476 | purC | -4.6 | -3.7 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0002 | thrA | -4.4 | -21.5 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b4006 | purH | -4.4 | -12.9 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0523 | purE | -4.4 | -5.2 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b1241 | adhE | -4.3 | -17.2 | fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) | compare |
| b2784 | relA | -4.3 | -17.6 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b4005 | purD | -4.3 | -12.8 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b2557 | purL | -4.2 | -14.1 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b2913 | serA | -4.2 | -16.2 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b4025 | pgi | -4.2 | -14.8 | glucose-6-phosphate isomerase (NCBI) | compare |
| b4388 | serB | -4.1 | -8.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2329 | aroC | -4.0 | -10.3 | chorismate synthase (NCBI) | compare |
| b0908 | aroA | -4.0 | -14.5 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b1185 | dsbB | -4.0 | -2.7 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b2501 | ppk | -3.9 | -14.0 | polyphosphate kinase (NCBI) | compare |
| b3860 | dsbA | -3.9 | -3.8 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b0902 | pflA | -3.9 | -11.9 | pyruvate formate lyase activating enzyme 1 (NCBI) | compare |
| b1850 | eda | -3.5 | -4.7 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b3960 | argH | -3.5 | -19.7 | argininosuccinate lyase (NCBI) | compare |
| b1261 | trpB | -3.5 | -6.6 | tryptophan synthase subunit beta (NCBI) | compare |
| b0903 | pflB | -3.4 | -17.2 | pyruvate formate lyase I (NCBI) | compare |
| b0720 | gltA | -3.4 | -9.3 | citrate synthase (NCBI) | compare |
| b0889 | lrp | -3.4 | -5.5 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b2312 | purF | -3.3 | -8.4 | amidophosphoribosyltransferase (NCBI) | compare |
| b2499 | purM | -3.3 | -6.6 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b4237 | nrdG | -3.2 | -13.8 | anaerobic ribonucleotide reductase activating protein (NCBI) | compare |
| b0145 | dksA | -3.2 | -3.1 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0522 | purK | -3.2 | -10.7 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b0142 | folK | -3.1 | -1.4 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b3172 | argG | -3.1 | -15.6 | argininosuccinate synthase (NCBI) | compare |
| b3930 | menA | -2.9 | -18.7 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) | compare |
| b1062 | pyrC | -2.9 | -4.8 | dihydroorotase (NCBI) | compare |
| b1865 | nudB | -2.9 | -2.6 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1290 | sapF | -2.9 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4238 | nrdD | -2.9 | -18.2 | anaerobic ribonucleoside triphosphate reductase (NCBI) | compare |
| b4242 | mgtA | -2.7 | -8.0 | magnesium transporter (NCBI) | compare |
| b1260 | trpA | -2.7 | -6.1 | tryptophan synthase subunit alpha (NCBI) | compare |
| b3916 | pfkA | -2.7 | -2.6 | 6-phosphofructokinase (NCBI) | compare |
| b1281 | pyrF | -2.7 | -2.5 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b3642 | pyrE | -2.6 | -1.8 | orotate phosphoribosyltransferase (NCBI) | compare |
| b1192 | ldcA | -2.6 | -3.1 | L,D-carboxypeptidase A (NCBI) | compare |
| b2188 | yejM | -2.6 | -14.2 | predicted hydrolase, inner membrane (NCBI) | compare |
| b0632 | dacA | -2.6 | -11.0 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b0688 | pgm | -2.6 | -3.0 | phosphoglucomutase (NCBI) | compare |
| b4402 | yjjY | -2.5 | -1.8 | hypothetical protein (NCBI) | compare |
| b3389 | aroB | -2.5 | -13.0 | 3-dehydroquinate synthase (NCBI) | compare |
| b3237 | argR | -2.5 | -7.4 | arginine repressor (NCBI) | compare |
| b2175 | spr | -2.5 | -5.0 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b2762 | cysH | -2.4 | -12.5 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0222 | lpcA | -2.4 | -2.3 | phosphoheptose isomerase (NCBI) | compare |
| b1677 | lpp | -2.4 | -3.3 | murein lipoprotein (NCBI) | compare |
| b0052 | pdxA | -2.4 | -15.0 | 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) | compare |
| b3911 | cpxA | -2.4 | -9.1 | two-component sensor protein (NCBI) | compare |
| b3281 | aroE | -2.3 | -15.9 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b3870 | glnA | -2.3 | -2.7 | glutamine synthetase (NCBI) | compare |
| b0945 | pyrD | -2.3 | -2.2 | dihydroorotate dehydrogenase (NCBI) | compare |
| b2320 | pdxB | -2.3 | -12.6 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b2839 | lysR | -2.3 | -5.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2763 | cysI | -2.3 | -12.2 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b4245 | pyrB | -2.2 | -2.2 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b4702 | mgtL | -2.2 | -2.1 | regulatory leader peptide for mgtA (NCBI) | compare |
| b4171 | miaA | -2.2 | -4.3 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b0728 | sucC | -2.1 | -7.8 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b3781 | trxA | -2.1 | -7.3 | thioredoxin 1 (VIMSS) | compare |
| b3229 | sspA | -2.1 | -5.5 | stringent starvation protein A (NCBI) | compare |
| b2764 | cysJ | -2.1 | -10.6 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b3941 | metF | -2.1 | -14.4 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b2564 | pdxJ | -2.1 | -8.3 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b0088 | murD | -2.1 | -4.2 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b1693 | aroD | -2.0 | -7.6 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b3368 | cysG | -2.0 | -16.0 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0438 | clpX | -2.0 | -3.0 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b3164 | pnp | -2.0 | -4.2 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b2313 | cvpA | -2.0 | -5.0 | membrane protein required for colicin V production (NCBI) | compare |
| b3829 | metE | -2.0 | -15.2 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b0032 | carA | -2.0 | -3.9 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b0564 | appY | -1.9 | -1.1 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b1687 | ydiJ | -1.9 | -10.8 | predicted FAD-linked oxidoreductase (NCBI) | compare |
| b3052 | rfaE | -1.9 | -2.8 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3979 | thrT | -1.9 | -0.8 | tRNA-Thr (NCBI) | compare |
| b2023 | hisH | -1.9 | -9.8 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b3828 | metR | -1.8 | -11.3 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b1101 | ptsG | -1.8 | -12.1 | fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) | compare |
| b0729 | sucD | -1.8 | -4.3 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b3838 | tatB | -1.8 | -8.1 | sec-independent translocase (NCBI) | compare |
| b0242 | proB | -1.8 | -8.2 | gamma-glutamyl kinase (NCBI) | compare |
| b2024 | hisA | -1.8 | -5.1 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b2414 | cysK | -1.8 | -10.6 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b1235 | rssB | -1.8 | -6.4 | response regulator of RpoS (NCBI) | compare |
| b2750 | cysC | -1.8 | -8.5 | adenylylsulfate kinase (NCBI) | compare |
| b0767 | ybhE | -1.7 | -5.3 | 6-phosphogluconolactonase (NCBI) | compare |
| b3791 | rffA | -1.7 | -4.3 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3493 | pitA | -1.7 | -7.5 | phosphate transporter, low-affinity (NCBI) | compare |
| b0439 | lon | -1.7 | -4.0 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3620 | rfaF | -1.7 | -2.9 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b2022 | hisB | -1.7 | -9.6 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2912 | ygfA | -1.7 | -2.6 | putative ligase (VIMSS) | compare |
| b2021 | hisC | -1.7 | -9.2 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b2600 | tyrA | -1.6 | -5.8 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b0926 | ycbK | -1.6 | -4.3 | hypothetical protein (NCBI) | compare |
| b1334 | fnr | -1.6 | -4.7 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |
| b2025 | hisF | -1.6 | -7.4 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b4481 | rffT | -1.6 | -4.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b4146 | yjeK | -1.6 | -1.5 | predicted lysine aminomutase (NCBI) | compare |
| b3774 | ilvC | -1.6 | -13.6 | ketol-acid reductoisomerase (NCBI) | compare |
| b3755 | yieP | -1.6 | -7.2 | predicted transcriptional regulator (NCBI) | compare |
| b2017 | yefM | -1.6 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b1613 | manA | -1.5 | -2.7 | mannose-6-phosphate isomerase (VIMSS) | compare |
| b0033 | carB | -1.5 | -2.7 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b3790 | rffC | -1.5 | -3.4 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b2752 | cysD | -1.5 | -5.8 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b0437 | clpP | -1.5 | -1.4 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b1593 | b1593 | -1.5 | -4.4 | orf, hypothetical protein (VIMSS) | compare |
| b1291 | sapD | -1.5 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0386 | proC | -1.5 | -2.9 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2020 | hisD | -1.5 | -7.8 | histidinol dehydrogenase (NCBI) | compare |
| b3770 | ilvE | -1.5 | -10.9 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b0113 | pdhR | -1.5 | -5.4 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b3621 | rfaC | -1.4 | -1.0 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3771 | ilvD | -1.4 | -11.2 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2318 | truA | -1.4 | -3.3 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2019 | hisG | -1.4 | -6.4 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3958 | argC | -1.4 | -9.7 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b4214 | cysQ | -1.4 | -10.7 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b0400 | phoR | -1.4 | -9.4 | sensory histidine kinase in two-component regulatory system with PhoB (NCBI) | compare |
| b0957 | ompA | -1.4 | -4.7 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b3741 | gidA | -1.3 | -1.8 | glucose-inhibited division protein A (NCBI) | compare |
| b0741 | pal | -1.3 | -1.5 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b1332 | ynaJ | -1.3 | -1.2 | predicted inner membrane protein (NCBI) | compare |
| b3429 | glgA | -1.3 | -9.6 | glycogen synthase (NCBI) | compare |
| b0425 | panE | -1.3 | -8.2 | 2-dehydropantoate 2-reductase (NCBI) | compare |
| b3205 | yhbJ | -1.3 | -4.8 | hypothetical protein (NCBI) | compare |
| b0619 | citA | -1.3 | -5.6 | sensory histidine kinase in two-component regulatory system with citB (NCBI) | compare |
| b0232 | yafN | -1.3 | -0.7 | predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) | compare |
| b3792 | wzxE | -1.3 | -2.3 | O-antigen translocase (NCBI) | compare |
| b3787 | rffD | -1.2 | -7.2 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b3772 | ilvA | -1.2 | -10.5 | threonine dehydratase (NCBI) | compare |
| b2330 | yfcB | -1.2 | -2.3 | putative adenine-specific methylase (VIMSS) | compare |
| b0243 | proA | -1.2 | -7.0 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b3786 | rffE | -1.2 | -8.3 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b1111 | ycfQ | -1.2 | -3.0 | orf, hypothetical protein (VIMSS) | compare |
| b3212 | gltB | -1.2 | -10.7 | glutamate synthase, large subunit (NCBI) | compare |
| b0077 | ilvI | -1.2 | -9.5 | acetolactate synthase III large subunit (NCBI) | compare |
| b3957 | argE | -1.2 | -10.0 | acetylornithine deacetylase (NCBI) | compare |
| b2751 | cysN | -1.2 | -7.2 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b3842 | rfaH | -1.2 | -3.6 | transcriptional activator RfaH (NCBI) | compare |
| b3213 | gltD | -1.2 | -8.0 | glutamate synthase, 4Fe-4S protein, small subunit (NCBI) | compare |
| b2808 | gcvA | -1.2 | -4.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1262 | trpC | -1.2 | -6.8 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b0078 | ilvH | -1.2 | -7.2 | acetolactate synthase small subunit (NCBI) | compare |
| b0073 | leuB | -1.2 | -8.8 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b3387 | dam | -1.1 | -5.4 | DNA adenine methylase (NCBI) | compare |
| b1686 | ydiI | -1.1 | -3.7 | hypothetical protein (NCBI) | compare |
| b0149 | mrcB | -1.1 | -7.6 | penicillin-binding protein 1b (NCBI) | compare |
| b3794 | rffM | -1.1 | -5.5 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b0053 | surA | -1.1 | -1.9 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b1084 | rne | -1.1 | -4.0 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b0904 | focA | -1.1 | -4.5 | formate transporter (NCBI) | compare |
| b1253 | yciA | -1.1 | -2.3 | predicted hydrolase (NCBI) | compare |
| b2518 | ndk | -1.1 | -2.8 | nucleoside diphosphate kinase (NCBI) | compare |
| b3959 | argB | -1.1 | -8.3 | acetylglutamate kinase (RefSeq) | compare |
| b1438 | ydcQ | -1.1 | -3.0 | predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b3359 | argD | -1.1 | -9.7 | bifunctional acetylornithine aminotransferase/ succinyldiaminopimelate aminotransferase (NCBI) | compare |
| b4175 | hflC | -1.1 | -7.5 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b3204 | ptsN | -1.1 | -4.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b3545 | proK | -1.1 | -3.0 | tRNA-Pro (NCBI) | compare |
| b1855 | lpxM | -1.1 | -4.0 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b4174 | hflK | -1.1 | -7.6 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b2026 | hisI | -1.1 | -5.5 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3252 | yhdA | -1.1 | -8.3 | conserved inner membrane protein (NCBI) | compare |
| b4390 | nadR | -1.0 | -7.8 | probable nadAB transcriptional regulator (VIMSS) | compare |
| b3169 | nusA | -1.0 | -1.7 | transcription elongation factor NusA (NCBI) | compare |
| b1127 | pepT | -1.0 | -5.5 | peptidase T (NCBI) | compare |
| b3631 | rfaG | -1.0 | -6.6 | glucosyltransferase I (NCBI) | compare |
| b0072 | leuC | -1.0 | -8.0 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b0881 | clpS | -1.0 | -3.0 | ATP-dependent Clp protease adaptor protein ClpS (NCBI) | compare |
| b2818 | argA | -1.0 | -6.7 | N-acetylglutamate synthase (NCBI) | compare |
| b2008 | yeeA | -1.0 | -5.5 | conserved inner membrane protein (NCBI) | compare |
| b0051 | ksgA | -1.0 | -3.9 | dimethyladenosine transferase (NCBI) | compare |
| b2424 | cysU | -1.0 | -3.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b3494 | yhiO | -1.0 | -6.0 | universal stress protein UspB (NCBI) | compare |
| b2422 | cysA | -1.0 | -6.0 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b1524 | yneH | -1.0 | -1.3 | predicted glutaminase (NCBI) | compare |
| b2504 | yfgG | -1.0 | -1.7 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b3055 | htrG | -1.0 | -5.3 | predicted signal transduction protein (SH3 domain) (NCBI) | compare |
| b4024 | lysC | -1.0 | -6.5 | aspartate kinase III (NCBI) | compare |
| b2498 | upp | -0.9 | -2.7 | uracil phosphoribosyltransferase (VIMSS) | compare |
| b1095 | fabF | -0.9 | -5.8 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b0912 | ihfB | -0.9 | -0.6 | integration host factor subunit beta (NCBI) | compare |
| b4179 | vacB | -0.9 | -3.7 | putative enzyme (VIMSS) | compare |
| b2156 | lysP | -0.9 | -7.2 | lysine transporter (NCBI) | compare |
| b3630 | rfaP | -0.9 | -4.5 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b0071 | leuD | -0.9 | -5.9 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b0133 | panC | -0.9 | -6.4 | pantoate--beta-alanine ligase (NCBI) | compare |