| | gene | name | fitness | t score | description | |
|---|
| b4388 | serB | -7.0 | -8.3 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2476 | purC | -6.7 | -4.6 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0907 | serC | -6.7 | -12.0 | phosphoserine aminotransferase (NCBI) | compare |
| b0004 | thrC | -6.7 | -14.2 | threonine synthase (NCBI) | compare |
| b0957 | ompA | -6.5 | -4.5 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b2838 | lysA | -6.5 | -16.8 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b2913 | serA | -6.5 | -12.4 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b1261 | trpB | -6.4 | -4.9 | tryptophan synthase subunit beta (NCBI) | compare |
| b3960 | argH | -5.8 | -21.3 | argininosuccinate lyase (NCBI) | compare |
| b3172 | argG | -5.7 | -19.2 | argininosuccinate synthase (NCBI) | compare |
| b1260 | trpA | -5.6 | -10.7 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0003 | thrB | -5.5 | -9.7 | homoserine kinase (NCBI) | compare |
| b2329 | aroC | -5.5 | -8.4 | chorismate synthase (NCBI) | compare |
| b2312 | purF | -5.5 | -5.4 | amidophosphoribosyltransferase (NCBI) | compare |
| b4005 | purD | -5.5 | -9.9 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b4006 | purH | -5.5 | -9.8 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2762 | cysH | -5.3 | -12.9 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b2750 | cysC | -5.0 | -9.0 | adenylylsulfate kinase (NCBI) | compare |
| b0522 | purK | -5.0 | -11.0 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b0002 | thrA | -4.9 | -20.0 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b0908 | aroA | -4.9 | -13.3 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2320 | pdxB | -4.9 | -12.7 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b2557 | purL | -4.8 | -12.9 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b3956 | ppc | -4.8 | -24.2 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b3281 | aroE | -4.8 | -19.0 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0523 | purE | -4.7 | -5.5 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2499 | purM | -4.6 | -7.0 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b0052 | pdxA | -4.5 | -16.7 | 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) | compare |
| b4214 | cysQ | -4.3 | -19.1 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b2021 | hisC | -4.3 | -9.0 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b3389 | aroB | -4.3 | -13.6 | 3-dehydroquinate synthase (NCBI) | compare |
| b1693 | aroD | -4.3 | -7.1 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b2564 | pdxJ | -4.2 | -9.6 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b2022 | hisB | -4.1 | -12.0 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2024 | hisA | -4.1 | -6.1 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b1677 | lpp | -3.9 | -3.8 | murein lipoprotein (NCBI) | compare |
| b3941 | metF | -3.9 | -19.3 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b0726 | sucA | -3.9 | -7.5 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b2025 | hisF | -3.9 | -7.5 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b4472 | yhdP | -3.9 | -26.4 | conserved membrane protein, predicted transporter (NCBI) | compare |
| b3829 | metE | -3.8 | -21.9 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) | compare |
| b2764 | cysJ | -3.8 | -12.8 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b3828 | metR | -3.8 | -19.0 | DNA-binding transcriptional activator, homocysteine-binding (NCBI) | compare |
| b1281 | pyrF | -3.7 | -2.5 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2023 | hisH | -3.6 | -7.8 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b0889 | lrp | -3.6 | -5.9 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b1185 | dsbB | -3.6 | -4.2 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b0243 | proA | -3.6 | -11.2 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0632 | dacA | -3.5 | -11.7 | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) | compare |
| b2020 | hisD | -3.5 | -16.1 | histidinol dehydrogenase (NCBI) | compare |
| b3781 | trxA | -3.5 | -7.1 | thioredoxin 1 (VIMSS) | compare |
| b3770 | ilvE | -3.4 | -17.6 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b1062 | pyrC | -3.4 | -4.7 | dihydroorotase (NCBI) | compare |
| b0242 | proB | -3.4 | -10.1 | gamma-glutamyl kinase (NCBI) | compare |
| b3771 | ilvD | -3.4 | -20.2 | dihydroxy-acid dehydratase (NCBI) | compare |
| b3774 | ilvC | -3.4 | -22.7 | ketol-acid reductoisomerase (NCBI) | compare |
| b2839 | lysR | -3.3 | -5.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2600 | tyrA | -3.3 | -7.0 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b3842 | rfaH | -3.3 | -2.3 | transcriptional activator RfaH (NCBI) | compare |
| b3164 | pnp | -3.3 | -5.8 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b0142 | folK | -3.2 | -1.4 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b0145 | dksA | -3.2 | -3.8 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0072 | leuC | -3.2 | -19.8 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b2763 | cysI | -3.2 | -12.6 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b0073 | leuB | -3.2 | -16.5 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b3627 | rfaI | -3.0 | -11.5 | UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) | compare |
| b3368 | cysG | -3.0 | -22.6 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0074 | leuA | -3.0 | -15.8 | 2-isopropylmalate synthase (NCBI) | compare |
| b2501 | ppk | -3.0 | -14.1 | polyphosphate kinase (NCBI) | compare |
| b3628 | rfaB | -2.9 | -12.7 | UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) | compare |
| b0688 | pgm | -2.9 | -2.8 | phosphoglucomutase (NCBI) | compare |
| b0071 | leuD | -2.9 | -12.1 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b3860 | dsbA | -2.9 | -8.6 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b0222 | lpcA | -2.8 | -1.9 | phosphoheptose isomerase (NCBI) | compare |
| b2479 | gcvR | -2.8 | -9.3 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b4242 | mgtA | -2.8 | -7.8 | magnesium transporter (NCBI) | compare |
| b3870 | glnA | -2.8 | -2.7 | glutamine synthetase (NCBI) | compare |
| b2512 | yfgL | -2.7 | -9.9 | protein assembly complex, lipoprotein component (NCBI) | compare |
| b3642 | pyrE | -2.7 | -1.9 | orotate phosphoribosyltransferase (NCBI) | compare |
| b2019 | hisG | -2.7 | -8.9 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3957 | argE | -2.7 | -19.9 | acetylornithine deacetylase (NCBI) | compare |
| b3631 | rfaG | -2.6 | -3.1 | glucosyltransferase I (NCBI) | compare |
| b1262 | trpC | -2.6 | -4.0 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b0386 | proC | -2.6 | -2.5 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b3958 | argC | -2.5 | -16.5 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b2500 | purN | -2.5 | -10.6 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b0945 | pyrD | -2.5 | -1.7 | dihydroorotate dehydrogenase (NCBI) | compare |
| b4245 | pyrB | -2.4 | -1.7 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b3959 | argB | -2.4 | -14.8 | acetylglutamate kinase (RefSeq) | compare |
| b1263 | trpD | -2.4 | -2.8 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b3008 | metC | -2.3 | -14.1 | cystathionine beta-lyase (NCBI) | compare |
| b2818 | argA | -2.3 | -14.5 | N-acetylglutamate synthase (NCBI) | compare |
| b2026 | hisI | -2.3 | -12.2 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b0032 | carA | -2.3 | -3.1 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b3620 | rfaF | -2.3 | -1.6 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b3630 | rfaP | -2.3 | -4.8 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b2912 | ygfA | -2.2 | -3.0 | putative ligase (VIMSS) | compare |
| b3052 | rfaE | -2.2 | -2.2 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b1865 | nudB | -2.2 | -2.1 | dATP pyrophosphohydrolase (NCBI) | compare |
| b2599 | pheA | -2.1 | -5.5 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b3390 | aroK | -2.1 | -2.8 | shikimate kinase I (NCBI) | compare |
| b0926 | ycbK | -2.1 | -7.9 | hypothetical protein (NCBI) | compare |
| b0438 | clpX | -2.1 | -3.7 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b0720 | gltA | -2.1 | -7.8 | citrate synthase (NCBI) | compare |
| b2414 | cysK | -2.1 | -12.1 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b1273 | yciN | -2.1 | -2.8 | hypothetical protein (NCBI) | compare |
| b3205 | yhbJ | -2.0 | -6.2 | hypothetical protein (NCBI) | compare |
| b2175 | spr | -2.0 | -4.9 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b2313 | cvpA | -2.0 | -3.4 | membrane protein required for colicin V production (NCBI) | compare |
| b3204 | ptsN | -2.0 | -5.3 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1264 | trpE | -2.0 | -4.5 | anthranilate synthase component I (NCBI) | compare |
| b1290 | sapF | -2.0 | -2.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0585 | fes | -2.0 | -10.9 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b0928 | aspC | -2.0 | -7.6 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b0683 | fur | -1.9 | -2.1 | ferric uptake regulator (NCBI) | compare |
| b3772 | ilvA | -1.8 | -14.2 | threonine dehydratase (NCBI) | compare |
| b0888 | trxB | -1.8 | -5.8 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b1236 | galU | -1.8 | -1.2 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b1291 | sapD | -1.8 | -2.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0209 | yafD | -1.8 | -9.8 | hypothetical protein (NCBI) | compare |
| b1235 | rssB | -1.8 | -6.5 | response regulator of RpoS (NCBI) | compare |
| b0149 | mrcB | -1.7 | -10.6 | penicillin-binding protein 1b (NCBI) | compare |
| b2144 | sanA | -1.7 | -13.3 | hypothetical protein (NCBI) | compare |
| b3916 | pfkA | -1.7 | -4.0 | 6-phosphofructokinase (NCBI) | compare |
| b2318 | truA | -1.7 | -3.9 | tRNA pseudouridine synthase A (NCBI) | compare |
| b3849 | trkH | -1.7 | -11.2 | potassium transporter (NCBI) | compare |
| b4025 | pgi | -1.7 | -11.1 | glucose-6-phosphate isomerase (NCBI) | compare |
| b1292 | sapC | -1.7 | -2.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0113 | pdhR | -1.7 | -6.4 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b1830 | prc | -1.7 | -4.6 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b0437 | clpP | -1.7 | -1.1 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b2742 | nlpD | -1.6 | -8.9 | predicted outer membrane lipoprotein (NCBI) | compare |
| b0033 | carB | -1.6 | -2.9 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b4171 | miaA | -1.6 | -4.1 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b0741 | pal | -1.6 | -1.1 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b2188 | yejM | -1.6 | -9.8 | predicted hydrolase, inner membrane (NCBI) | compare |
| b3527 | yhjJ | -1.6 | -14.4 | predicted zinc-dependent peptidase (NCBI) | compare |
| b0049 | apaH | -1.6 | -1.1 | diadenosinetetraphosphatase (NCBI) | compare |
| b3150 | yraP | -1.6 | -8.4 | hypothetical protein (NCBI) | compare |
| b1855 | lpxM | -1.6 | -5.7 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b2752 | cysD | -1.6 | -6.4 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b3650 | spoT | -1.6 | -8.9 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b3621 | rfaC | -1.5 | -1.0 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3838 | tatB | -1.5 | -6.5 | sec-independent translocase (NCBI) | compare |
| b1613 | manA | -1.5 | -2.5 | mannose-6-phosphate isomerase (VIMSS) | compare |
| b0589 | fepG | -1.5 | -8.6 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0590 | fepD | -1.5 | -9.4 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0592 | fepB | -1.5 | -10.2 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0053 | surA | -1.5 | -1.0 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b1111 | ycfQ | -1.5 | -2.9 | orf, hypothetical protein (VIMSS) | compare |
| b2340 | sixA | -1.5 | -4.7 | phosphohistidine phosphatase (NCBI) | compare |
| b2601 | aroF | -1.5 | -7.4 | 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible (NCBI) | compare |
| b3791 | rffA | -1.4 | -4.0 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b0200 | gmhB | -1.4 | -0.9 | hypothetical protein (NCBI) | compare |
| b0588 | fepC | -1.4 | -8.2 | iron-enterobactin transporter subunit (NCBI) | compare |
| b3790 | rffC | -1.4 | -3.3 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b2751 | cysN | -1.4 | -8.2 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b3792 | wzxE | -1.4 | -2.4 | O-antigen translocase (NCBI) | compare |
| b3912 | cpxR | -1.4 | -8.0 | DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) | compare |
| b1192 | ldcA | -1.3 | -2.8 | L,D-carboxypeptidase A (NCBI) | compare |
| b0439 | lon | -1.3 | -3.9 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0759 | galE | -1.3 | -7.8 | UDP-galactose-4-epimerase (VIMSS) | compare |
| b3426 | glpD | -1.3 | -1.2 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b3924 | fpr | -1.3 | -8.2 | ferredoxin-NADP reductase (NCBI) | compare |
| b3939 | metB | -1.3 | -9.7 | cystathionine gamma-synthase (NCBI) | compare |
| b2330 | yfcB | -1.3 | -2.5 | putative adenine-specific methylase (VIMSS) | compare |
| b3229 | sspA | -1.2 | -4.2 | stringent starvation protein A (NCBI) | compare |
| b4451 | ryhB | -1.2 | -2.0 | Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) | compare |
| b3926 | glpK | -1.2 | -9.6 | glycerol kinase (NCBI) | compare |
| b3993 | thiE | -1.2 | -7.5 | thiamine-phosphate pyrophosphorylase (NCBI) | compare |
| b2689 | yqaA | -1.2 | -3.6 | conserved inner membrane protein (NCBI) | compare |
| b3632 | rfaQ | -1.2 | -10.9 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b3163 | nlpI | -1.2 | -4.0 | hypothetical protein (NCBI) | compare |
| b4179 | vacB | -1.2 | -4.4 | putative enzyme (VIMSS) | compare |
| b0001 | thrL | -1.2 | -1.3 | thr operon leader peptide (NCBI) | compare |
| b4558 | yifL | -1.1 | -3.5 | predicted lipoprotein (NCBI) | compare |
| b1874 | cutC | -1.1 | -0.7 | copper homeostasis protein (NCBI) | compare |
| b2611 | ypjD | -1.1 | -7.2 | predicted inner membrane protein (RefSeq) | compare |
| b0075 | leuL | -1.1 | -3.4 | leu operon leader peptide (NCBI) | compare |
| b3784 | rfe | -1.1 | -7.6 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b1176 | minC | -1.1 | -3.2 | septum formation inhibitor (NCBI) | compare |
| b3994 | thiC | -1.1 | -8.6 | thiamine biosynthesis protein ThiC (NCBI) | compare |
| b2103 | thiD | -1.1 | -7.0 | phosphomethylpyrimidine kinase (NCBI) | compare |
| b0630 | lipB | -1.1 | -1.5 | protein of lipoate biosynthesis (VIMSS) | compare |
| b3388 | damX | -1.1 | -9.0 | hypothetical protein (NCBI) | compare |
| b3247 | cafA | -1.1 | -8.5 | bundles of cytoplasmic filaments (VIMSS) | compare |
| b2569 | lepA | -1.1 | -3.6 | GTP-binding protein LepA (NCBI) | compare |
| b3095 | yqjA | -1.1 | -7.3 | conserved inner membrane protein (NCBI) | compare |
| b0912 | ihfB | -1.1 | -0.7 | integration host factor subunit beta (NCBI) | compare |
| b3398 | yrfF | -1.1 | -3.3 | predicted inner membrane protein (NCBI) | compare |
| b3786 | rffE | -1.1 | -7.3 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b1084 | rne | -1.0 | -4.1 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b0077 | ilvI | -1.0 | -7.8 | acetolactate synthase III large subunit (NCBI) | compare |
| b4146 | yjeK | -1.0 | -2.1 | predicted lysine aminomutase (NCBI) | compare |
| b3493 | pitA | -1.0 | -5.7 | phosphate transporter, low-affinity (NCBI) | compare |
| b3500 | gor | -1.0 | -2.0 | glutathione reductase (NCBI) | compare |
| b1332 | ynaJ | -1.0 | -1.0 | predicted inner membrane protein (NCBI) | compare |
| b0750 | nadA | -1.0 | -5.1 | quinolinate synthetase (NCBI) | compare |
| b0078 | ilvH | -1.0 | -7.0 | acetolactate synthase small subunit (NCBI) | compare |
| b3787 | rffD | -1.0 | -6.3 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |