Experiment set50IT031 for Escherichia coli BW25113

Compare to:

Dictyostellum sp.mixed culture-1

200 most important genes:

  gene name fitness t score description  
b0437 clpP -8.1 -5.6 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3839 tatC -6.5 -16.3 TatABCE protein translocation system subunit (NCBI) compare
b1192 ldcA -5.8 -9.3 L,D-carboxypeptidase A (NCBI) compare
b3792 wzxE -5.4 -6.5 O-antigen translocase (NCBI) compare
b4242 mgtA -5.2 -7.2 magnesium transporter (NCBI) compare
b3405 ompR -5.0 -12.1 osmolarity response regulator (NCBI) compare
b0957 ompA -5.0 -7.5 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4702 mgtL -4.9 -3.3 regulatory leader peptide for mgtA (NCBI) compare
b3021 ygiT -4.8 -4.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0740 tolB -4.8 -8.5 translocation protein TolB precursor (NCBI) compare
b0149 mrcB -4.7 -25.1 penicillin-binding protein 1b (NCBI) compare
b0739 tolA -4.7 -6.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0438 clpX -4.7 -12.5 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0737 tolQ -4.7 -5.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2017 yefM -4.7 -2.1 orf, hypothetical protein (VIMSS) compare
b0738 tolR -4.6 -3.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4042 dgkA -4.3 -3.0 diacylglycerol kinase (NCBI) compare
b3791 rffA -4.3 -15.3 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b2830 nudH -4.3 -5.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b3962 udhA -4.3 -8.1 putative oxidoreductase (VIMSS) compare
b3390 aroK -4.2 -4.7 shikimate kinase I (NCBI) compare
b4481 rffT -4.1 -13.6 4-alpha-L-fucosyltransferase (NCBI) compare
b3790 rffC -4.1 -10.5 TDP-fucosamine acetyltransferase (RefSeq) compare
b2912 ygfA -4.1 -8.0 putative ligase (VIMSS) compare
b3838 tatB -4.0 -8.1 sec-independent translocase (NCBI) compare
b0741 pal -4.0 -8.0 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2318 truA -3.8 -5.2 tRNA pseudouridine synthase A (NCBI) compare
b3035 tolC -3.8 -11.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b4218 ytfL -3.8 -15.5 predicted inner membrane protein (NCBI) compare
b3613 yibP -3.6 -12.2 putative membrane protein (VIMSS) compare
b2312 purF -3.5 -6.5 amidophosphoribosyltransferase (NCBI) compare
b0926 ycbK -3.5 -9.0 hypothetical protein (NCBI) compare
b0222 lpcA -3.4 -4.1 phosphoheptose isomerase (NCBI) compare
b4006 purH -3.4 -16.5 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b3609 secB -3.3 -4.0 export protein SecB (NCBI) compare
b2188 yejM -3.3 -13.9 predicted hydrolase, inner membrane (NCBI) compare
b3619 rfaD -3.2 -9.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3794 rffM -3.2 -13.3 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3082 ygjM -3.2 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2808 gcvA -3.1 -8.7 DNA-binding transcriptional dual regulator (NCBI) compare
b4202 rpsR -3.0 -2.9 30S ribosomal protein S18 (NCBI) compare
b2476 purC -3.0 -5.3 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b0523 purE -2.9 -4.8 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b0912 ihfB -2.9 -9.0 integration host factor subunit beta (NCBI) compare
b2499 purM -2.9 -6.8 phosphoribosylaminoimidazole synthetase (NCBI) compare
b3150 yraP -2.9 -11.5 hypothetical protein (NCBI) compare
b4179 vacB -2.9 -10.9 putative enzyme (VIMSS) compare
b3341 rpsG -2.9 -3.0 30S ribosomal protein S7 (NCBI) compare
b4005 purD -2.9 -11.4 phosphoribosylamine--glycine ligase (NCBI) compare
b0890 ftsK -2.9 -9.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3811 xerC -2.8 -5.2 site-specific tyrosine recombinase XerC (NCBI) compare
b1677 lpp -2.8 -3.5 murein lipoprotein (NCBI) compare
b1712 ihfA -2.7 -6.0 integration host factor subunit alpha (NCBI) compare
b0522 purK -2.7 -9.9 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b3786 rffE -2.6 -16.8 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3620 rfaF -2.6 -10.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1823 cspC -2.6 -3.2 stress protein, member of the CspA-family (NCBI) compare
b3787 rffD -2.6 -14.4 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b3784 rfe -2.6 -17.7 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3621 rfaC -2.6 -10.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b4146 yjeK -2.5 -4.4 predicted lysine aminomutase (NCBI) compare
b2557 purL -2.4 -11.2 phosphoribosylformylglycinamidine synthase (NCBI) compare
b3706 trmE -2.4 -10.3 tRNA modification GTPase (NCBI) compare
b0632 dacA -2.4 -10.7 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b0688 pgm -2.3 -6.3 phosphoglucomutase (NCBI) compare
b4414 tff -2.3 -5.2 unknown RNA (NCBI) compare
b0033 carB -2.3 -14.7 carbamoyl-phosphate synthase large subunit (NCBI) compare
b2567 rnc -2.3 -1.5 ribonuclease III (NCBI) compare
b2894 xerD -2.2 -3.0 site-specific tyrosine recombinase XerD (NCBI) compare
b2175 spr -2.2 -7.2 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b2576 srmB -2.2 -5.5 ATP-dependent RNA helicase (NCBI) compare
b0051 ksgA -2.2 -6.8 dimethyladenosine transferase (NCBI) compare
b0049 apaH -2.2 -4.4 diadenosinetetraphosphatase (NCBI) compare
b3404 envZ -2.1 -9.3 osmolarity sensor protein (NCBI) compare
b3052 rfaE -2.1 -9.8 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1185 dsbB -2.1 -5.0 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b0630 lipB -2.1 -2.7 protein of lipoate biosynthesis (VIMSS) compare
b1236 galU -2.1 -7.6 glucose-1-phosphate uridylyltransferase (NCBI) compare
b4203 rplI -2.0 -8.9 50S ribosomal protein L9 (NCBI) compare
b3726 pstA -2.0 -7.2 phosphate transporter subunit (NCBI) compare
b3728 pstS -2.0 -3.7 phosphate transporter subunit (NCBI) compare
b3741 gidA -2.0 -6.2 glucose-inhibited division protein A (NCBI) compare
b1286 rnb -2.0 -5.3 exoribonuclease II (NCBI) compare
b1861 ruvA -1.9 -3.2 Holliday junction DNA helicase motor protein (NCBI) compare
b1129 phoQ -1.9 -1.3 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b4593 ymgI -1.9 -1.3 hypothetical protein (RefSeq) compare
b3642 pyrE -1.9 -4.2 orotate phosphoribosyltransferase (NCBI) compare
b4701 sokX -1.9 -1.2 sok-related sRNA, function unknown (RefSeq) compare
b0032 carA -1.9 -5.3 carbamoyl-phosphate synthase small subunit (NCBI) compare
b1830 prc -1.9 -8.2 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3199 yrbK -1.9 -2.9 hypothetical protein (NCBI) compare
b1130 phoP -1.9 -1.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0564 appY -1.8 -0.8 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b4375 prfC -1.8 -7.7 peptide chain release factor 3 (NCBI) compare
b3469 zntA -1.8 -9.8 zinc, cobalt and lead efflux system (NCBI) compare
b0053 surA -1.8 -8.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1831 proQ -1.8 -5.6 putative solute/DNA competence effector (NCBI) compare
b2564 pdxJ -1.8 -5.8 pyridoxal phosphate biosynthetic protein (NCBI) compare
b0114 aceE -1.8 -2.3 pyruvate dehydrogenase subunit E1 (NCBI) compare
b4232 fbp -1.7 -11.7 fructose-1,6-bisphosphatase (NCBI) compare
b4239 treC -1.7 -3.3 trehalose-6-P hydrolase (NCBI) compare
b3725 pstB -1.7 -1.1 phosphate transporter subunit (NCBI) compare
b4245 pyrB -1.6 -9.5 aspartate carbamoyltransferase catalytic subunit (NCBI) compare
b1863 ruvC -1.6 -3.4 Holliday junction resolvase (NCBI) compare
b3911 cpxA -1.6 -8.8 two-component sensor protein (NCBI) compare
b3250 mreC -1.6 -2.2 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b4169 amiB -1.6 -11.2 N-acetylmuramoyl-l-alanine amidase II (NCBI) compare
b2313 cvpA -1.6 -5.8 membrane protein required for colicin V production (NCBI) compare
b3631 rfaG -1.5 -13.0 glucosyltransferase I (NCBI) compare
b3183 obgE -1.5 -2.4 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2330 yfcB -1.5 -2.8 putative adenine-specific methylase (VIMSS) compare
b2501 ppk -1.5 -9.6 polyphosphate kinase (NCBI) compare
b0400 phoR -1.5 -9.3 sensory histidine kinase in two-component regulatory system with PhoB (NCBI) compare
b4651 yibW -1.5 -1.0 no description compare
b0014 dnaK -1.5 -2.8 molecular chaperone DnaK (NCBI) compare
b1860 ruvB -1.5 -1.4 Holliday junction DNA helicase B (NCBI) compare
b4402 yjjY -1.5 -1.8 hypothetical protein (NCBI) compare
b3387 dam -1.5 -11.6 DNA adenine methylase (NCBI) compare
b3164 pnp -1.5 -4.3 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3229 sspA -1.5 -3.9 stringent starvation protein A (NCBI) compare
b3727 pstC -1.5 -8.7 phosphate transporter subunit (NCBI) compare
b0658 ybeX -1.5 -1.0 predicteed ion transport (NCBI) compare
b1176 minC -1.4 -4.5 septum formation inhibitor (NCBI) compare
b0232 yafN -1.4 -0.9 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3860 dsbA -1.4 -7.8 periplasmic protein disulfide isomerase I (NCBI) compare
b4172 hfq -1.4 -1.3 RNA-binding protein Hfq (NCBI) compare
b2516 yfgA -1.4 -5.1 hypothetical protein (NCBI) compare
b1438 ydcQ -1.4 -2.0 predicted DNA-binding transcriptional regulator (RefSeq) compare
b4698 mgrR -1.4 -2.2 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b1261 trpB -1.4 -4.3 tryptophan synthase subunit beta (NCBI) compare
b2742 nlpD -1.4 -8.9 predicted outer membrane lipoprotein (NCBI) compare
b1105 ycfM -1.4 -4.7 predicted outer membrane lipoprotein (NCBI) compare
b3463 ftsE -1.4 -1.3 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0200 gmhB -1.4 -2.5 hypothetical protein (NCBI) compare
b1874 cutC -1.3 -1.8 copper homeostasis protein (NCBI) compare
b4025 pgi -1.3 -7.5 glucose-6-phosphate isomerase (NCBI) compare
b3630 rfaP -1.3 -9.7 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3842 rfaH -1.3 -6.3 transcriptional activator RfaH (NCBI) compare
b0949 uup -1.3 -8.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b2350 yfdG -1.3 -4.8 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b0726 sucA -1.3 -4.7 alpha-ketoglutarate decarboxylase (NCBI) compare
b0623 cspE -1.3 -3.1 cold shock protein E (NCBI) compare
b1332 ynaJ -1.3 -0.8 predicted inner membrane protein (NCBI) compare
b3940 metL -1.3 -6.1 bifunctional aspartate kinase II/homoserine dehydrogenase II (NCBI) compare
b3292 zntR -1.3 -3.4 zinc-responsive transcriptional regulator (NCBI) compare
b3026 qseC -1.3 -5.5 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0439 lon -1.2 -5.6 DNA-binding ATP-dependent protease La (NCBI) compare
b4676 yoaK -1.2 -0.8 expressed protein (RefSeq) compare
b4177 purA -1.2 -1.4 adenylosuccinate synthetase (NCBI) compare
b3162 deaD -1.2 -5.3 inducible ATP-independent RNA helicase (VIMSS) compare
b1095 fabF -1.2 -6.0 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3426 glpD -1.2 -4.2 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b4201 priB -1.2 -3.0 primosomal replication protein N (NCBI) compare
b0226 dinJ -1.1 -4.5 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1773 ydjI -1.1 -2.7 predicted aldolase (NCBI) compare
b3472 b3472 -1.1 -6.6 orf, hypothetical protein (VIMSS) compare
b3863 polA -1.1 -1.5 DNA polymerase I (NCBI) compare
b3386 rpe -1.1 -1.4 ribulose-phosphate 3-epimerase (NCBI) compare
b0605 ahpC -1.1 -3.9 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b0945 pyrD -1.1 -6.5 dihydroorotate dehydrogenase (NCBI) compare
b3375 yhfR -1.1 -7.3 putative transcriptional regulator (VIMSS) compare
b2620 smpB -1.1 -1.9 SsrA-binding protein (NCBI) compare
b0677 nagA -1.1 -5.1 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b3388 damX -1.0 -8.2 hypothetical protein (NCBI) compare
b3203 yhbH -1.0 -4.7 predicted ribosome-associated, sigma 54 modulation protein (NCBI) compare
b1304 pspA -1.0 -3.5 regulatory protein for phage-shock-protein operon (NCBI) compare
b3644 yicC -1.0 -5.2 hypothetical protein (NCBI) compare
b2652 ileY -1.0 -0.9 tRNA-Ile (NCBI) compare
b3290 trkA -1.0 -2.5 potassium transporter peripheral membrane component (NCBI) compare
b0814 ompX -1.0 -4.5 outer membrane protein X (NCBI) compare
b2144 sanA -1.0 -7.4 hypothetical protein (NCBI) compare
b1159 mcrA -1.0 -1.3 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b3836 b3836 -1.0 -2.3 orf, hypothetical protein (VIMSS) compare
b1175 minD -1.0 -4.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3389 aroB -1.0 -6.3 3-dehydroquinate synthase (NCBI) compare
b1855 lpxM -1.0 -3.7 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0015 dnaJ -0.9 -6.1 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3238 yhcN -0.9 -2.6 orf, hypothetical protein (VIMSS) compare
b3169 nusA -0.9 -2.6 transcription elongation factor NusA (NCBI) compare
b0145 dksA -0.9 -1.4 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2683 ygaH -0.9 -3.6 predicted inner membrane protein (NCBI) compare
b3650 spoT -0.9 -4.7 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b3462 ftsX -0.9 -5.0 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3545 proK -0.9 -2.6 tRNA-Pro (NCBI) compare
b1730 ydjO -0.9 -1.0 predicted protein (RefSeq) compare
b2320 pdxB -0.9 -6.6 erythronate-4-phosphate dehydrogenase (NCBI) compare
b2741 rpoS -0.9 -3.2 RNA polymerase sigma factor (NCBI) compare
b1062 pyrC -0.9 -4.2 dihydroorotase (NCBI) compare
b0633 rlpA -0.9 -6.8 minor lipoprotein (NCBI) compare
b3806 cyaA -0.9 -4.2 adenylate cyclase (NCBI) compare
b2784 relA -0.9 -5.8 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0434 yajG -0.9 -5.1 putative polymerase/proteinase (VIMSS) compare
b1824 yobF -0.9 -1.4 hypothetical protein (NCBI) compare
b2569 lepA -0.8 -3.9 GTP-binding protein LepA (NCBI) compare
b1850 eda -0.8 -2.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0722 sdhD -0.8 -3.2 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b0889 lrp -0.8 -2.0 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b0052 pdxA -0.8 -5.6 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) compare
b4533 ynfO -0.8 -1.8 Qin prophage; predicted protein (NCBI) compare
b0059 hepA -0.8 -6.8 ATP-dependent helicase HepA (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For micoeukaryotes Pelleted after growth overnight in LB+Kan50 in Escherichia coli BW25113

For micoeukaryotes Pelleted after growth overnight in LB+Kan50 across organisms