Experiment set4S47 for Pseudomonas sp. RS175

Compare to:

L-Isoleucine carbon source 10 mM

200 most important genes:

  gene name fitness t score description  
PFR28_04933 -6.2 -4.3 Imidazole glycerol phosphate synthase subunit HisF compare
PFR28_02444 -5.2 -4.2 Leucine-responsive regulatory protein compare
PFR28_02823 -5.2 -3.5 3-isopropylmalate dehydratase small subunit 1 compare
PFR28_01884 -5.1 -6.3 putative enoyl-CoA hydratase echA8 compare
PFR28_02448 -5.1 -8.5 Dihydrolipoyl dehydrogenase compare
PFR28_02447 -5.0 -10.7 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex compare
PFR28_02824 -4.9 -8.2 3-isopropylmalate dehydratase large subunit compare
PFR28_01878 -4.7 -9.5 putative HTH-type transcriptional regulator conserved
PFR28_02925 -4.7 -8.9 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) compare
PFR28_01882 -4.6 -8.8 Acetyl-CoA acetyltransferase conserved
PFR28_04071 -4.6 -2.0 Multifunctional CCA protein compare
PFR28_02924 -4.5 -3.1 2-methyl-aconitate isomerase compare
PFR28_02445 -4.5 -12.6 2-oxoisovalerate dehydrogenase subunit alpha compare
PFR28_02821 -4.4 -19.8 3-isopropylmalate dehydrogenase compare
PFR28_04932 -4.4 -7.9 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase compare
PFR28_04986 -4.4 -6.7 Phosphoribosyl-AMP cyclohydrolase compare
PFR28_04930 -4.2 -10.5 Imidazole glycerol phosphate synthase subunit HisH compare
PFR28_03363 -4.1 -17.5 Ornithine carbamoyltransferase 1, anabolic compare
PFR28_02446 -4.1 -16.8 2-oxoisovalerate dehydrogenase subunit beta compare
PFR28_00186 -4.0 -8.1 ATP phosphoribosyltransferase compare
PFR28_02927 -4.0 -14.2 2-methylcitrate synthase compare
PFR28_02928 -3.9 -10.7 2-methylisocitrate lyase compare
PFR28_04929 -3.9 -7.0 Histidine biosynthesis bifunctional protein HisB compare
PFR28_02449 -3.9 -14.9 putative branched-chain-amino-acid aminotransferase compare
PFR28_01881 -3.8 -3.7 putative oxidoreductase compare
PFR28_05125 -3.8 -9.3 ATP phosphoribosyltransferase regulatory subunit compare
PFR28_00305 -3.7 -14.3 2-isopropylmalate synthase compare
PFR28_04902 -3.6 -6.0 Inner membrane protein YgaZ compare
PFR28_04246 -3.5 -13.3 Bifunctional methionine biosynthesis protein MetXA/MetW compare
PFR28_03714 -3.5 -15.2 RNA polymerase-binding transcription factor DksA compare
PFR28_01883 -3.5 -7.9 Acyl-CoA dehydrogenase conserved
PFR28_03837 -3.4 -9.7 Leucine-responsive regulatory protein compare
PFR28_04245 -3.4 -16.8 Homoserine O-succinyltransferase compare
PFR28_03697 -3.4 -14.2 Ketol-acid reductoisomerase (NADP(+)) compare
PFR28_05105 -3.3 -7.7 Phosphoserine phosphatase SerB2 compare
PFR28_02811 -3.3 -3.2 Amidophosphoribosyltransferase compare
PFR28_04628 -3.3 -2.3 Thiol:disulfide interchange protein DsbA compare
PFR28_03721 -3.3 -3.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PFR28_00187 -3.3 -12.1 Histidinol dehydrogenase compare
PFR28_04832 -3.1 -12.5 putative phosphatase compare
PFR28_04202 -3.0 -3.6 5,10-methylenetetrahydrofolate reductase compare
PFR28_04518 -3.0 -11.6 2-oxoglutarate carboxylase small subunit compare
PFR28_04278 -3.0 -10.8 Dihydroxy-acid dehydratase compare
PFR28_01366 -2.9 -9.9 Sulfite reductase [ferredoxin] compare
PFR28_02810 -2.9 -15.7 O-succinylhomoserine sulfhydrylase compare
PFR28_04903 -2.9 -6.9 hypothetical protein compare
PFR28_03635 -2.9 -2.0 Malate:quinone oxidoreductase compare
PFR28_03860 -2.9 -4.8 putative murein peptide carboxypeptidase compare
PFR28_04985 -2.8 -5.0 Phosphoribosyl-ATP pyrophosphatase compare
PFR28_02603 -2.8 -8.0 Siroheme synthase compare
PFR28_03427 -2.8 -7.7 Sensor histidine kinase RcsC compare
PFR28_04517 -2.8 -13.9 Oxaloacetate decarboxylase alpha chain compare
PFR28_00098 -2.8 -10.0 Nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
PFR28_04030 -2.7 -6.0 hypothetical protein compare
PFR28_04519 -2.7 -11.1 HTH-type transcriptional activator CmpR compare
PFR28_01880 -2.6 -8.3 Acetyl-coenzyme A synthetase conserved
PFR28_03844 -2.6 -7.1 Thiamine-phosphate synthase compare
PFR28_01877 -2.6 -11.3 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
PFR28_01014 -2.5 -2.7 Pyrimidine/purine nucleoside phosphorylase compare
PFR28_04491 -2.5 -6.2 putative acyl-CoA thioester hydrolase compare
PFR28_03223 -2.5 -9.0 GTP pyrophosphokinase compare
PFR28_03388 -2.4 -13.3 Quinolinate synthase A compare
PFR28_03218 -2.4 -7.3 Phosphoribosylglycinamide formyltransferase compare
PFR28_01365 -2.4 -6.6 hypothetical protein compare
PFR28_00188 -2.4 -10.6 Histidinol-phosphate aminotransferase compare
PFR28_04110 -2.3 -14.0 Malate synthase G compare
PFR28_03130 -2.3 -4.0 Streptothricin hydrolase compare
PFR28_04842 -2.2 -6.4 D-3-phosphoglycerate dehydrogenase compare
PFR28_03856 -2.1 -1.4 LPS-assembly lipoprotein LptE compare
PFR28_01930 -2.1 -3.0 HTH-type transcriptional regulator McbR compare
PFR28_04308 -2.0 -1.4 Amino-acid acetyltransferase compare
PFR28_03699 -2.0 -2.6 Acetolactate synthase isozyme 3 large subunit compare
PFR28_03653 -1.9 -3.7 Molybdopterin-synthase adenylyltransferase compare
PFR28_04252 -1.9 -8.9 Thiazole synthase compare
PFR28_04521 -1.9 -4.5 HTH-type transcriptional regulator HexR compare
PFR28_01376 -1.9 -2.3 hypothetical protein compare
PFR28_00787 -1.9 -3.2 hypothetical protein compare
PFR28_02719 -1.8 -3.0 Integration host factor subunit alpha compare
PFR28_04565 -1.8 -10.9 Protein RarD compare
PFR28_00688 -1.8 -1.7 hypothetical protein compare
PFR28_03217 -1.8 -1.7 Phosphoribosylformylglycinamidine cyclo-ligase compare
PFR28_05091 -1.8 -12.8 Phosphomethylpyrimidine synthase compare
PFR28_03698 -1.8 -7.7 Acetolactate synthase isozyme 3 small subunit compare
PFR28_04072 -1.8 -3.3 Bifunctional folate synthesis protein compare
PFR28_03369 -1.8 -8.6 Glycerol-3-phosphate regulon repressor compare
PFR28_01081 -1.7 -1.2 hypothetical protein compare
PFR28_00403 -1.7 -3.5 Regulator of sigma-E protease RseP compare
PFR28_00926 -1.7 -2.2 hypothetical protein compare
PFR28_02973 -1.7 -12.8 HTH-type transcriptional regulator NorG conserved
PFR28_03420 -1.7 -4.4 hypothetical protein compare
PFR28_00837 -1.7 -5.3 hypothetical protein compare
PFR28_03843 -1.6 -6.3 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
PFR28_00241 -1.6 -3.3 Disulfide bond formation protein B compare
PFR28_00966 -1.6 -10.7 HTH-type transcriptional regulator CysB compare
PFR28_00980 -1.6 -1.7 ATP-dependent RNA helicase DeaD compare
PFR28_03463 -1.6 -1.6 hypothetical protein compare
PFR28_04103 -1.5 -6.7 Biotin synthase compare
PFR28_04936 -1.5 -3.3 Carboxy-terminal processing protease CtpB compare
PFR28_04887 -1.5 -2.9 '3'(2'),5'-bisphosphate nucleotidase CysQ' transl_table=11 compare
PFR28_04380 -1.4 -2.0 Transcriptional regulator SutA compare
PFR28_02740 -1.4 -2.7 hypothetical protein compare
PFR28_03413 -1.4 -3.0 Holliday junction ATP-dependent DNA helicase RuvA compare
PFR28_00913 -1.4 -6.1 Integration host factor subunit beta compare
PFR28_05212 -1.4 -7.8 Sensor histidine kinase RcsC compare
PFR28_00695 -1.4 -2.0 Sulfur carrier protein TusA compare
PFR28_03657 -1.4 -4.8 Beta-barrel assembly-enhancing protease compare
PFR28_01691 -1.3 -3.2 hypothetical protein compare
PFR28_02838 -1.3 -8.5 Aromatic-amino-acid aminotransferase compare
PFR28_00541 -1.3 -1.8 hypothetical protein compare
PFR28_00325 -1.3 -2.6 Inner membrane protein YpjD compare
PFR28_04325 -1.3 -4.0 5-formyltetrahydrofolate cyclo-ligase compare
PFR28_03282 -1.3 -6.5 Arginine N-succinyltransferase subunit alpha compare
PFR28_01080 -1.3 -8.3 Oxygen-independent coproporphyrinogen III oxidase compare
PFR28_05201 -1.3 -3.4 Precorrin-6Y C(5,15)-methyltransferase [decarboxylating] compare
PFR28_04436 -1.3 -5.6 hypothetical protein compare
PFR28_03429 -1.2 -4.3 Thiamine-phosphate synthase compare
PFR28_00271 -1.2 -3.0 hypothetical protein compare
PFR28_01378 -1.2 -2.9 Magnesium-chelatase 38 kDa subunit compare
PFR28_00572 -1.1 -6.3 HTH-type transcriptional regulator HexR compare
PFR28_00561 -1.1 -1.7 Phosphogluconate dehydratase compare
PFR28_04782 -1.1 -7.8 hypothetical protein compare
PFR28_04345 -1.1 -9.5 Polyphosphate kinase compare
PFR28_00442 -1.1 -3.9 hypothetical protein compare
PFR28_01003 -1.1 -3.0 hypothetical protein compare
PFR28_00722 -1.1 -2.7 hypothetical protein compare
PFR28_03255 -1.1 -7.3 Chemotaxis protein methyltransferase Cher2 compare
PFR28_01113 -1.1 -2.6 DNA topoisomerase 1 compare
PFR28_01718 -1.1 -2.4 Response regulator receiver protein CpdR compare
PFR28_01602 -1.0 -8.6 NAD-specific glutamate dehydrogenase compare
PFR28_01408 -1.0 -1.5 hypothetical protein compare
PFR28_00851 -1.0 -0.9 Flagellum site-determining protein YlxH compare
PFR28_02283 -1.0 -2.0 hypothetical protein compare
PFR28_00159 -1.0 -5.2 hypothetical protein compare
PFR28_01037 -1.0 -5.6 Phosphoenolpyruvate synthase regulatory protein compare
PFR28_03631 -1.0 -1.2 hypothetical protein compare
PFR28_01855 -1.0 -1.0 Hypoxic response protein 1 compare
PFR28_00855 -0.9 -5.3 hypothetical protein compare
PFR28_03902 -0.9 -1.0 hypothetical protein compare
PFR28_03412 -0.9 -2.6 Holliday junction ATP-dependent DNA helicase RuvB compare
PFR28_00690 -0.9 -3.5 RNA polymerase sigma-H factor compare
PFR28_01156 -0.9 -4.5 hypothetical protein compare
PFR28_00622 -0.9 -1.6 Beta-ketoadipyl-CoA thiolase compare
PFR28_01230 -0.9 -1.6 Lon protease compare
PFR28_00853 -0.9 -5.2 Chemotaxis protein CheY compare
PFR28_04941 -0.9 -2.7 Protein-export protein SecB compare
PFR28_04052 -0.9 -7.2 hypothetical protein compare
PFR28_05079 -0.9 -4.0 hypothetical protein compare
PFR28_01095 -0.9 -4.0 Cbb3-type cytochrome c oxidase subunit CcoN1 compare
PFR28_00139 -0.9 -4.7 HTH-type transcriptional regulator LutR compare
PFR28_01084 -0.9 -1.7 hypothetical protein compare
PFR28_03865 -0.9 -4.5 Endolytic peptidoglycan transglycosylase RlpA compare
PFR28_01142 -0.9 -6.8 Transaldolase compare
PFR28_01587 -0.9 -2.0 hypothetical protein compare
PFR28_04230 -0.9 -3.3 Response regulator PleD compare
PFR28_02298 -0.9 -1.3 hypothetical protein compare
PFR28_01600 -0.8 -1.7 HTH-type transcriptional regulator KdgR compare
PFR28_04059 -0.8 -5.9 N-acetylmuramate alpha-1-phosphate uridylyltransferase compare
PFR28_01470 -0.8 -1.7 Transcriptional regulatory protein WalR compare
PFR28_01431 -0.8 -1.2 Chemotaxis protein CheW compare
PFR28_03414 -0.8 -1.3 Crossover junction endodeoxyribonuclease RuvC compare
PFR28_03931 -0.8 -2.1 hypothetical protein compare
PFR28_03229 -0.8 -3.3 hypothetical protein compare
PFR28_01190 -0.8 -0.9 hypothetical protein compare
PFR28_00861 -0.8 -5.9 Chemotaxis protein CheW compare
PFR28_01231 -0.8 -1.9 Peptidyl-prolyl cis-trans isomerase D compare
PFR28_01094 -0.8 -2.8 hypothetical protein compare
PFR28_04585 -0.8 -2.9 Chromosome partitioning protein ParA compare
PFR28_03362 -0.8 -1.6 hypothetical protein compare
PFR28_04607 -0.8 -1.2 Organic hydroperoxide resistance protein OhrB compare
PFR28_01570 -0.8 -2.8 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical' transl_table=11 compare
PFR28_02734 -0.8 -2.9 Ribose operon repressor compare
PFR28_04723 -0.7 -5.8 NAD(P) transhydrogenase subunit beta compare
PFR28_00208 -0.7 -3.4 Dihydromonapterin reductase compare
PFR28_02050 -0.7 -2.7 hypothetical protein compare
PFR28_02817 -0.7 -2.7 tRNA pseudouridine synthase A compare
PFR28_01375 -0.7 -1.7 hypothetical protein compare
PFR28_01845 -0.7 -2.5 Cysteine/O-acetylserine efflux protein compare
PFR28_01176 -0.7 -2.0 hypothetical protein compare
PFR28_01410 -0.7 -4.1 Response regulator GacA compare
PFR28_02344 -0.7 -3.7 Chaperone protein HscC compare
PFR28_01153 -0.7 -0.8 hypothetical protein compare
PFR28_03507 -0.7 -2.4 Protein YrdA compare
PFR28_02846 -0.7 -3.5 Adaptive-response sensory-kinase SasA compare
PFR28_02210 -0.7 -1.2 cAMP-activated global transcriptional regulator CRP compare
PFR28_00274 -0.7 -1.8 hypothetical protein compare
PFR28_00299 -0.7 -1.1 hypothetical protein compare
PFR28_03227 -0.7 -4.2 Signal transduction histidine-protein kinase BarA compare
PFR28_04119 -0.7 -2.5 putative GST-like protein YibF compare
PFR28_03666 -0.7 -0.8 hypothetical protein compare
PFR28_01450 -0.7 -1.1 hypothetical protein compare
PFR28_01386 -0.7 -1.8 Glutamine transport ATP-binding protein GlnQ compare
PFR28_00941 -0.7 -0.8 Potassium-transporting ATPase KdpC subunit compare
PFR28_00340 -0.7 -2.7 NADPH dehydrogenase compare
PFR28_04958 -0.7 -1.1 hypothetical protein compare
PFR28_04056 -0.7 -4.3 Membrane-bound lytic murein transglycosylase F compare
PFR28_01119 -0.7 -2.3 Beta-hexosaminidase compare
PFR28_03266 -0.7 -1.0 hypothetical protein compare
PFR28_04369 -0.7 -1.1 hypothetical protein compare
PFR28_03596 -0.7 -1.0 Transcriptional regulator MraZ compare
PFR28_00089 -0.7 -1.0 Transcription termination/antitermination protein NusA compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source L-Isoleucine in Pseudomonas sp. RS175

For carbon source L-Isoleucine across organisms