Experiment set4S450 for Escherichia coli ECRC98

Compare to:

Control_ECRC98_WM

200 most important genes:

  gene name fitness t score description  
JDDGAC_14710 thrL -8.3 -3.3 thr operon leader peptide compare
JDDGAC_25875 purC -7.8 -4.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
JDDGAC_14325 leuD -7.3 -5.0 3-isopropylmalate dehydratase small subunit compare
JDDGAC_14315 leuB -7.2 -5.0 3-isopropylmalate dehydrogenase compare
JDDGAC_11485 purE -6.9 -3.8 N5-carboxyaminoimidazole ribonucleotide mutase compare
JDDGAC_11490 purK -6.6 -9.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_24895 -6.3 -1.5 Leader peptide of chorismate mutase-P-prephenate dehydratase compare
JDDGAC_25755 purM -6.2 -10.6 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_06275 ycgL -6.1 -2.3 Protein YcgL compare
JDDGAC_26575 aroC -6.1 -3.8 chorismate synthase compare
JDDGAC_14795 serB -6.0 -6.4 phosphoserine phosphatase compare
JDDGAC_16935 purH -5.9 -16.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_24045 cysH -5.9 -8.8 phosphoadenosine phosphosulfate reductase compare
JDDGAC_14320 leuC1 -5.8 -13.3 3-isopropylmalate dehydratase large subunit 1 compare
JDDGAC_18265 ilvE -5.7 -11.8 branched-chain-amino-acid transaminase compare
JDDGAC_25135 purL -5.6 -21.2 phosphoribosylformylglycinamidine synthase compare
JDDGAC_27740 -5.6 -1.3 regulator compare
JDDGAC_05850 -5.5 -2.2 hypothetical protein compare
JDDGAC_15675 cysQ -5.5 -8.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_28970 -5.3 -1.2 DNA-binding protein compare
JDDGAC_24115 cysC -5.3 -10.0 Adenylyl-sulfate kinase compare
JDDGAC_01535 chbB -5.2 -2.4 PTS N,N'-diacetylchitobiose transporter subunit IIB compare
JDDGAC_21185 aroE -5.2 -3.6 shikimate dehydrogenase compare
JDDGAC_23100 serA -5.1 -12.1 phosphoglycerate dehydrogenase compare
JDDGAC_17300 metB -5.0 -9.2 cystathionine gamma-synthase compare
JDDGAC_24890 pheA -5.0 -8.4 bifunctional chorismate mutase/prephenate dehydratase compare
JDDGAC_05810 -5.0 -2.8 DNA-binding protein compare
JDDGAC_10455 pal -5.0 -2.5 peptidoglycan-associated lipoprotein Pal compare
JDDGAC_17290 metF -5.0 -7.9 methylenetetrahydrofolate reductase compare
JDDGAC_23980 ygcW -4.9 -1.6 Uncharacterized oxidoreductase YgcW compare
JDDGAC_20745 aroB -4.8 -5.7 3-dehydroquinate synthase compare
JDDGAC_21580 lptC -4.8 -1.4 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_18245 ilvC -4.8 -12.2 ketol-acid reductoisomerase compare
JDDGAC_11260 ybdZ -4.8 -1.1 Enterobactin biosynthesis protein YbdZ compare
JDDGAC_06305 minE -4.8 -1.1 cell division topological specificity factor MinE compare
JDDGAC_06430 -4.7 -1.1 phage tail protein compare
JDDGAC_18215 trxA -4.6 -2.1 thioredoxin TrxA compare
JDDGAC_14435 apaG -4.6 -2.1 Co2+/Mg2+ efflux protein ApaG compare
JDDGAC_10810 nagB -4.6 -5.7 glucosamine-6-phosphate deaminase compare
JDDGAC_22595 metC -4.5 -10.4 cystathionine beta-lyase compare
JDDGAC_14705 thrA -4.5 -16.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
JDDGAC_07025 -4.5 -1.4 DUF4406 domain-containing protein compare
JDDGAC_13940 dksA -4.5 -6.5 RNA polymerase-binding protein DksA compare
JDDGAC_09100 serC -4.5 -9.4 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_17455 pfkA -4.5 -3.1 6-phosphofructokinase compare
JDDGAC_24035 cysJ -4.4 -11.6 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
JDDGAC_09095 aroA -4.4 -11.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
JDDGAC_16900 metA -4.4 -5.2 homoserine O-succinyltransferase compare
JDDGAC_03280 -4.4 -1.4 hypothetical protein compare
JDDGAC_26675 purF -4.3 -7.6 amidophosphoribosyltransferase compare
JDDGAC_09385 lrp -4.3 -4.4 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_25435 guaB -4.3 -7.7 IMP dehydrogenase compare
JDDGAC_05210 trpCF -4.2 -6.7 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
JDDGAC_02145 rsxA -4.2 -1.4 electron transport complex subunit RsxA compare
JDDGAC_15870 purA -4.2 -2.5 adenylosuccinate synthase compare
JDDGAC_07675 -4.1 -1.3 Oligogalacturonate-specific porin protein KdgM compare
JDDGAC_05200 trpE -4.1 -7.6 anthranilate synthase component I compare
JDDGAC_00935 yebF -4.1 -1.3 Protein YebF compare
JDDGAC_18255 ilvA -4.0 -7.8 threonine ammonia-lyase, biosynthetic compare
JDDGAC_27660 -4.0 -2.2 hypothetical protein compare
JDDGAC_18260 ilvD -4.0 -10.0 dihydroxy-acid dehydratase compare
JDDGAC_05215 trpB -3.9 -4.1 tryptophan synthase subunit beta compare
JDDGAC_06360 yciE -3.9 -1.2 Protein YciF compare
JDDGAC_29105 -3.9 -1.3 tail assembly protein compare
JDDGAC_20210 -3.8 -2.3 DUF3261 domain-containing protein compare
JDDGAC_28600 hisF -3.8 -1.2 Imidazole glycerol phosphate synthase subunit HisF compare
JDDGAC_01220 yoaG -3.8 -1.2 Protein YoaG compare
JDDGAC_24040 cysI -3.7 -6.5 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
JDDGAC_29980 sopA -3.6 -1.2 plasmid-partitioning protein SopA compare
JDDGAC_28630 hisG -3.6 -5.3 ATP phosphoribosyltransferase compare
JDDGAC_09600 ybjN -3.6 -3.0 Uncharacterized protein YbjN compare
JDDGAC_29425 -3.6 -1.2 Prophage protein compare
JDDGAC_29495 -3.6 -2.5 9-O-acetyl-N-acetylneuraminic acid deacetylase compare
JDDGAC_05135 -3.6 -1.9 Protein, C-ter, truncated protein compare
JDDGAC_14440 apaH -3.6 -2.0 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
JDDGAC_27065 yfaE -3.5 -1.1 ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE compare
JDDGAC_25750 purN -3.5 -6.7 phosphoribosylglycinamide formyltransferase compare
JDDGAC_22885 yggS -3.5 -4.2 pyridoxal phosphate homeostasis protein compare
JDDGAC_14075 acnB -3.5 -2.4 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
JDDGAC_28615 hisB -3.5 -3.6 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
JDDGAC_01015 rsmF -3.5 -2.2 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
JDDGAC_10470 tolR -3.4 -5.1 colicin uptake protein TolR compare
JDDGAC_13715 yaeR -3.4 -2.2 VOC family protein compare
JDDGAC_28205 -3.4 -2.0 ADP-ribosylglycohydrolase family protein compare
JDDGAC_27680 -3.3 -1.5 Ead/Ea22-like protein compare
JDDGAC_27995 -3.3 -1.5 IS4 family transposase compare
JDDGAC_05205 trpD -3.3 -6.9 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
JDDGAC_21505 gltD -3.3 -8.2 glutamate synthase subunit GltD compare
JDDGAC_24885 tyrA -3.2 -9.6 bifunctional chorismate mutase/prephenate dehydrogenase compare
JDDGAC_02140 rsxB -3.1 -2.0 electron transport complex subunit RsxB compare
JDDGAC_06425 -3.1 -1.4 phage minor tail protein L compare
JDDGAC_08445 lomR -3.1 -1.0 Ail/Lom family protein compare
JDDGAC_19635 cspA -3.1 -1.2 Major cold shock protein compare
JDDGAC_05985 galU -3.1 -4.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_00825 nudB -3.1 -0.9 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_10575 odhB -3.0 -2.6 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
JDDGAC_14700 thrB -3.0 -4.3 homoserine kinase compare
JDDGAC_28685 -3.0 -1.2 AlpA family transcriptional regulator compare
JDDGAC_24800 rnfH -3.0 -3.0 RnfH family protein compare
JDDGAC_21510 gltB -3.0 -12.0 glutamate synthase large subunit compare
JDDGAC_16940 purD -2.9 -4.2 Phosphoribosylamine--glycine ligase compare
JDDGAC_14310 -2.9 -6.8 2-isopropylmalate synthase compare
JDDGAC_24735 rrrD -2.9 -0.9 lysozyme compare
JDDGAC_00750 flhe -2.9 -2.0 flagellar protein FlhE compare
JDDGAC_10375 galT -2.9 -3.2 galactose-1-phosphate uridylyltransferase compare
JDDGAC_14695 thrC -2.8 -3.6 threonine synthase compare
JDDGAC_06645 -2.8 -2.4 hypothetical protein compare
JDDGAC_28620 hisC -2.8 -3.8 histidinol-phosphate transaminase compare
JDDGAC_28595 hisIE -2.7 -2.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
JDDGAC_21715 argG -2.7 -6.1 argininosuccinate synthase compare
JDDGAC_05525 -2.7 -0.9 host nuclease inhibitor protein compare
JDDGAC_25410 yfgM -2.7 -1.1 ancillary SecYEG translocon subunit YfgM compare
JDDGAC_29165 -2.7 -0.9 toxin of the YeeV-YeeU toxin-antitoxin system compare
JDDGAC_20810 cysG -2.6 -5.9 siroheme synthase CysG compare
JDDGAC_00680 flhC -2.6 -1.6 flagellar transcriptional regulator FlhC compare
JDDGAC_03670 lsrC -2.6 -1.7 autoinducer 2 ABC transporter permease LsrC compare
JDDGAC_05220 trpA -2.6 -2.2 tryptophan synthase subunit alpha compare
JDDGAC_26745 yfcD -2.6 -1.3 NUDIX hydrolase YfcD compare
JDDGAC_29975 sopA -2.5 -3.3 plasmid-partitioning protein SopA compare
JDDGAC_19320 rfaF -2.5 -1.8 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_18405 mnmG -2.5 -3.7 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_27045 -2.5 -0.8 hypothetical protein compare
JDDGAC_06120 prmC -2.4 -1.6 peptide chain release factor N(5)-glutamine methyltransferase compare
JDDGAC_05730 ymfQ -2.4 -1.4 Bacteriophage Mu-like, Gp48 compare
JDDGAC_28605 hisA -2.4 -2.5 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase compare
JDDGAC_17200 argH -2.4 -5.4 argininosuccinate lyase compare
JDDGAC_11920 glnK -2.3 -1.3 P-II family nitrogen regulator compare
JDDGAC_06045 -2.3 -2.0 hypothetical protein compare
JDDGAC_04640 -2.3 -2.7 transcriptional regulator compare
JDDGAC_14535 carB -2.3 -7.9 carbamoyl-phosphate synthase large subunit compare
JDDGAC_25415 bamB -2.2 -3.4 outer membrane protein assembly factor BamB compare
JDDGAC_18250 ilvY -2.2 -4.0 HTH-type transcriptional activator IlvY compare
JDDGAC_29015 -2.2 -1.5 phage major capsid protein compare
JDDGAC_25045 rseA -2.2 -2.5 anti-sigma-E factor RseA compare
JDDGAC_02060 ydhI -2.2 -0.9 Uncharacterized protein YdhI compare
JDDGAC_10465 tolA -2.1 -1.9 cell envelope integrity protein TolA compare
JDDGAC_11235 fepD -2.1 -1.9 ferrienterobactin ABC transporter permease compare
JDDGAC_01040 prc -2.1 -6.0 carboxy terminal-processing peptidase compare
JDDGAC_27880 -2.1 -1.1 Phage protein compare
JDDGAC_01695 ydiV -2.1 -1.4 anti-FlhDC factor compare
JDDGAC_27000 yfaU -2.1 -2.2 2-keto-3-deoxy-L-rhamnonate aldolase compare
JDDGAC_11975 -2.1 -2.9 Lon protease compare
JDDGAC_15475 argF -2.1 -7.3 ornithine carbamoyltransferase compare
JDDGAC_17210 argC -2.1 -4.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
JDDGAC_06180 -2.1 -2.3 PTS-dependent dihydroxyacetone kinase compare
JDDGAC_17735 glnG -2.1 -1.0 nitrogen regulation protein NR(I) compare
JDDGAC_08805 yccU -2.1 -1.3 Uncharacterized protein YccU compare
JDDGAC_08190 efeU -2.0 -1.3 Ferrous iron permease EfeU compare
JDDGAC_19120 tnp-IS3 -2.0 -0.9 IS3 family transposase compare
JDDGAC_00770 cutC -2.0 -1.5 copper homeostasis protein CutC compare
JDDGAC_07825 -2.0 -0.8 Membrane protein compare
JDDGAC_22545 ftsP -2.0 -1.7 cell division protein FtsP compare
JDDGAC_04925 ycjM -2.0 -1.8 Glucosylglycerate phosphorylase compare
JDDGAC_04025 mddA -2.0 -2.2 L-methionine sulfoximine/L-methionine sulfone acetyltransferase compare
JDDGAC_26875 elaD -1.9 -1.4 ElaD/SseL family deubiquitinase compare
JDDGAC_28625 hisD -1.9 -4.8 Histidinol dehydrogenase compare
JDDGAC_18020 corA -1.9 -2.5 magnesium/cobalt transporter CorA compare
JDDGAC_23480 -1.9 -1.5 type III secretion apparatus protein OrgA/MxiK compare
JDDGAC_01960 cfa -1.9 -1.7 cyclopropane fatty acyl phospholipid synthase compare
JDDGAC_06675 -1.9 -1.4 hypothetical protein compare
JDDGAC_24540 ygaP -1.9 -0.8 thiosulfate sulfurtransferase YgaP compare
JDDGAC_28610 hisH -1.9 -1.3 imidazole glycerol phosphate synthase subunit HisH compare
JDDGAC_26670 cvpA -1.9 -2.6 colicin V production protein compare
JDDGAC_09995 moaC -1.8 -2.7 cyclic pyranopterin monophosphate synthase MoaC compare
JDDGAC_01440 ynjD -1.8 -1.3 Uncharacterized ABC transporter ATP-binding protein YnjD compare
JDDGAC_09290 oRF81 -1.8 -0.7 Uncharacterized protein in GpA 5'region compare
JDDGAC_03650 lsrG -1.8 -1.5 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase compare
JDDGAC_04370 rri1 -1.8 -1.6 phage tail protein compare
JDDGAC_01895 ydhU -1.8 -2.5 Putative cytochrome YdhU compare
JDDGAC_19280 rfaG -1.8 -3.2 Lipopolysaccharide core biosynthesis protein RfaG compare
JDDGAC_14430 rsmA -1.8 -1.6 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA compare
JDDGAC_08575 -1.8 -1.1 lysozyme compare
JDDGAC_02225 ydgA -1.8 -1.5 Protein YdgA compare
JDDGAC_21290 acrS -1.8 -1.6 multidrug efflux transporter transcriptional repressor AcrS compare
JDDGAC_25440 guaA -1.8 -1.6 glutamine-hydrolyzing GMP synthase compare
JDDGAC_04865 ycjW -1.7 -1.8 Uncharacterized HTH-type transcriptional regulator YcjW compare
JDDGAC_23570 yqeH -1.7 -1.0 Uncharacterized protein YqeH compare
JDDGAC_02135 rsxC -1.7 -3.6 electron transport complex subunit RsxC compare
JDDGAC_28845 -1.7 -1.1 hypothetical protein compare
JDDGAC_01235 dgcP -1.7 -2.9 diguanylate cyclase DgcP compare
JDDGAC_05255 -1.7 -0.9 hypothetical protein compare
JDDGAC_27710 exoD -1.7 -1.3 Putative uncharacterized protein ExoD compare
JDDGAC_23505 ygeI -1.7 -1.6 Uncharacterized protein YgeI compare
JDDGAC_27705 -1.7 -1.1 cruciferin compare
JDDGAC_20665 ompR_G63V -1.7 -2.6 two-component system response regulator OmpR compare
JDDGAC_26500 -1.7 -1.8 Uncharacterized protein YfdF compare
JDDGAC_23140 ygfB -1.7 -1.4 UPF0149 family protein YgfB compare
JDDGAC_03940 nhoA -1.7 -1.5 N-hydroxyarylamine O-acetyltransferase compare
JDDGAC_17215 argE -1.6 -7.5 acetylornithine deacetylase compare
JDDGAC_23065 -1.6 -1.5 Putative acetyl-CoA hydrolase/transferase compare
JDDGAC_28690 -1.6 -1.0 hypothetical protein compare
JDDGAC_10690 yafF -1.6 -0.9 ISAs1 family transposase compare
JDDGAC_00525 -1.6 -1.7 derepression protein compare
JDDGAC_06025 narJ -1.6 -0.6 nitrate reductase molybdenum cofactor assembly chaperone compare
JDDGAC_03285 -1.6 -1.2 DUF968 domain-containing protein compare
JDDGAC_08130 cadC1 -1.6 -0.8 transcriptional regulator compare
JDDGAC_30180 repA2 -1.6 -3.6 Replication regulatory protein repA2 compare
JDDGAC_06760 -1.6 -1.0 Mutator family transposase compare
JDDGAC_09955 ybhQ -1.6 -2.1 Inner membrane protein YbhQ compare
JDDGAC_18275 ilvG -1.6 -7.4 acetolactate synthase 2 catalytic subunit compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in no phage control experiments

For no phage control No phage across organisms