Experiment set4S449 for Escherichia coli ECRC98

Compare to:

Control_ECRC98_WM

200 most important genes:

  gene name fitness t score description  
JDDGAC_25875 purC -8.0 -5.2 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
JDDGAC_17300 metB -7.6 -5.3 cystathionine gamma-synthase compare
JDDGAC_25755 purM -7.4 -8.8 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_05215 trpB -7.3 -5.1 tryptophan synthase subunit beta compare
JDDGAC_16935 purH -7.2 -11.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_22595 metC -7.1 -9.8 cystathionine beta-lyase compare
JDDGAC_05220 trpA -6.8 -4.0 tryptophan synthase subunit alpha compare
JDDGAC_16900 metA -6.7 -4.7 homoserine O-succinyltransferase compare
JDDGAC_18265 ilvE -6.6 -14.7 branched-chain-amino-acid transaminase compare
JDDGAC_24895 -6.4 -1.7 Leader peptide of chorismate mutase-P-prephenate dehydratase compare
JDDGAC_24045 cysH -6.4 -9.8 phosphoadenosine phosphosulfate reductase compare
JDDGAC_26575 aroC -6.4 -4.4 chorismate synthase compare
JDDGAC_17290 metF -6.3 -9.3 methylenetetrahydrofolate reductase compare
JDDGAC_14320 leuC1 -6.1 -11.8 3-isopropylmalate dehydratase large subunit 1 compare
JDDGAC_26675 purF -5.8 -13.2 amidophosphoribosyltransferase compare
JDDGAC_05210 trpCF -5.8 -10.4 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
JDDGAC_05200 trpE -5.8 -10.4 anthranilate synthase component I compare
JDDGAC_15675 cysQ -5.7 -8.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_27740 -5.7 -1.5 regulator compare
JDDGAC_14700 thrB -5.7 -6.6 homoserine kinase compare
JDDGAC_25135 purL -5.7 -15.7 phosphoribosylformylglycinamidine synthase compare
JDDGAC_24115 cysC -5.6 -10.3 Adenylyl-sulfate kinase compare
JDDGAC_10355 acrZ -5.5 -1.5 multidrug efflux pump accessory protein AcrZ compare
JDDGAC_14315 leuB -5.4 -13.5 3-isopropylmalate dehydrogenase compare
JDDGAC_09100 serC -5.4 -10.1 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_25435 guaB -5.4 -5.2 IMP dehydrogenase compare
JDDGAC_18245 ilvC -5.4 -16.3 ketol-acid reductoisomerase compare
JDDGAC_05205 trpD -5.3 -7.2 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
JDDGAC_20745 aroB -5.3 -5.1 3-dehydroquinate synthase compare
JDDGAC_10575 odhB -5.2 -3.3 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
JDDGAC_23100 serA -5.2 -10.7 phosphoglycerate dehydrogenase compare
JDDGAC_10455 pal -5.1 -2.9 peptidoglycan-associated lipoprotein Pal compare
JDDGAC_16940 purD -5.1 -8.0 Phosphoribosylamine--glycine ligase compare
JDDGAC_15900 miaA -5.0 -2.6 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
JDDGAC_11485 purE -5.0 -4.9 N5-carboxyaminoimidazole ribonucleotide mutase compare
JDDGAC_24035 cysJ -4.9 -11.0 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
JDDGAC_18260 ilvD -4.9 -15.4 dihydroxy-acid dehydratase compare
JDDGAC_09095 aroA -4.9 -15.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
JDDGAC_18255 ilvA -4.9 -8.2 threonine ammonia-lyase, biosynthetic compare
JDDGAC_11490 purK -4.9 -7.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_25045 rseA -4.9 -5.7 anti-sigma-E factor RseA compare
JDDGAC_21580 lptC -4.8 -1.6 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_06305 minE -4.8 -1.3 cell division topological specificity factor MinE compare
JDDGAC_18215 trxA -4.8 -2.5 thioredoxin TrxA compare
JDDGAC_14795 serB -4.8 -6.2 phosphoserine phosphatase compare
JDDGAC_25750 purN -4.6 -7.1 phosphoribosylglycinamide formyltransferase compare
JDDGAC_10470 tolR -4.5 -9.2 colicin uptake protein TolR compare
JDDGAC_14705 thrA -4.4 -15.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
JDDGAC_24890 pheA -4.4 -7.9 bifunctional chorismate mutase/prephenate dehydratase compare
JDDGAC_14710 thrL -4.4 -1.9 thr operon leader peptide compare
JDDGAC_15870 purA -4.4 -2.9 adenylosuccinate synthase compare
JDDGAC_24040 cysI -4.2 -7.2 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
JDDGAC_14325 leuD -4.2 -4.5 3-isopropylmalate dehydratase small subunit compare
JDDGAC_17730 glnL -4.1 -4.7 nitrogen regulation protein NR(II) compare
JDDGAC_11470 cysS -4.1 -1.1 cysteine--tRNA ligase compare
JDDGAC_14695 thrC -4.1 -6.5 threonine synthase compare
JDDGAC_09385 lrp -4.1 -4.5 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_14310 -3.9 -8.4 2-isopropylmalate synthase compare
JDDGAC_22140 yqiM -3.9 -1.4 Protein YqiM compare
JDDGAC_28600 hisF -3.9 -1.4 Imidazole glycerol phosphate synthase subunit HisF compare
JDDGAC_18250 ilvY -3.8 -8.3 HTH-type transcriptional activator IlvY compare
JDDGAC_14440 apaH -3.7 -2.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
JDDGAC_10465 tolA -3.7 -2.6 cell envelope integrity protein TolA compare
JDDGAC_27065 yfaE -3.7 -1.4 ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE compare
JDDGAC_21185 aroE -3.7 -6.0 shikimate dehydrogenase compare
JDDGAC_24885 tyrA -3.6 -10.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
JDDGAC_13940 dksA -3.6 -4.7 RNA polymerase-binding protein DksA compare
JDDGAC_19070 escG -3.6 -1.3 type III secretion system LEE needle protein cochaperone EscG compare
JDDGAC_13640 gmhB -3.5 -2.0 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase compare
JDDGAC_21505 gltD -3.4 -8.4 glutamate synthase subunit GltD compare
JDDGAC_19320 rfaF -3.4 -2.2 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_05985 galU -3.4 -4.1 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_21715 argG -3.3 -7.0 argininosuccinate synthase compare
JDDGAC_06890 -3.2 -1.2 HNH endonuclease compare
JDDGAC_25440 guaA -3.2 -2.2 glutamine-hydrolyzing GMP synthase compare
JDDGAC_08445 lomR -3.2 -1.2 Ail/Lom family protein compare
JDDGAC_03940 nhoA -3.2 -3.7 N-hydroxyarylamine O-acetyltransferase compare
JDDGAC_22885 yggS -3.1 -5.0 pyridoxal phosphate homeostasis protein compare
JDDGAC_00825 nudB -3.1 -1.1 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_28605 hisA -3.1 -3.3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase compare
JDDGAC_28610 hisH -3.0 -3.3 imidazole glycerol phosphate synthase subunit HisH compare
JDDGAC_17200 argH -3.0 -7.4 argininosuccinate lyase compare
JDDGAC_26670 cvpA -3.0 -3.9 colicin V production protein compare
JDDGAC_18065 cyaY -2.9 -2.0 iron donor protein CyaY compare
JDDGAC_03210 -2.9 -1.1 hypothetical protein compare
JDDGAC_16385 ytcA -2.7 -1.0 Uncharacterized protein YtcA compare
JDDGAC_25905 yffB -2.7 -1.6 ArsC family reductase compare
JDDGAC_03615 yneJ -2.7 -2.1 Uncharacterized HTH-type transcriptional regulator YneJ compare
JDDGAC_28620 hisC -2.7 -4.3 histidinol-phosphate transaminase compare
JDDGAC_28595 hisIE -2.6 -3.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
JDDGAC_10210 -2.6 -1.6 lysis protein compare
JDDGAC_21510 gltB -2.5 -12.3 glutamate synthase large subunit compare
JDDGAC_17455 pfkA -2.5 -3.4 6-phosphofructokinase compare
JDDGAC_26745 yfcD -2.5 -1.6 NUDIX hydrolase YfcD compare
JDDGAC_06760 -2.4 -1.5 Mutator family transposase compare
JDDGAC_03725 ydeR -2.4 -2.3 Uncharacterized fimbrial-like protein YdeR compare
JDDGAC_19280 rfaG -2.4 -5.1 Lipopolysaccharide core biosynthesis protein RfaG compare
JDDGAC_14535 carB -2.3 -8.6 carbamoyl-phosphate synthase large subunit compare
JDDGAC_15475 argF -2.3 -6.8 ornithine carbamoyltransferase compare
JDDGAC_17735 glnG -2.2 -1.3 nitrogen regulation protein NR(I) compare
JDDGAC_06300 minD -2.2 -2.0 septum site-determining protein MinD compare
JDDGAC_18070 cyaA -2.2 -2.0 class I adenylate cyclase compare
JDDGAC_24800 rnfH -2.2 -3.1 RnfH family protein compare
JDDGAC_10810 nagB -2.2 -2.7 glucosamine-6-phosphate deaminase compare
JDDGAC_09995 moaC -2.2 -3.1 cyclic pyranopterin monophosphate synthase MoaC compare
JDDGAC_06275 ycgL -2.2 -1.5 Protein YcgL compare
JDDGAC_03640 uxaB -2.2 -3.3 tagaturonate reductase compare
JDDGAC_07005 -2.2 -1.9 hypothetical protein compare
JDDGAC_14865 ytjA -2.1 -1.0 UPF0391 membrane protein YtjA compare
JDDGAC_25415 bamB -2.1 -3.3 outer membrane protein assembly factor BamB compare
JDDGAC_20810 cysG -2.1 -6.4 siroheme synthase CysG compare
JDDGAC_29975 sopA -2.1 -2.5 plasmid-partitioning protein SopA compare
JDDGAC_10110 -2.0 -1.8 phage minor tail protein L compare
JDDGAC_23140 ygfB -2.0 -2.2 UPF0149 family protein YgfB compare
JDDGAC_01815 ydiH -2.0 -1.6 Uncharacterized protein YdiH compare
JDDGAC_12090 pgpA -2.0 -1.3 phosphatidylglycerophosphatase A compare
JDDGAC_12115 nrdR -1.9 -1.3 transcriptional regulator NrdR compare
JDDGAC_22870 rdgB -1.9 -1.9 XTP/dITP diphosphatase compare
JDDGAC_23565 -1.9 -1.0 hypothetical protein compare
JDDGAC_23430 escR -1.8 -1.1 EscR/YscR/HrcR family type III secretion system export apparatus protein compare
JDDGAC_14540 carA -1.8 -5.5 carbamoyl phosphate synthase small subunit compare
JDDGAC_28685 -1.8 -1.3 AlpA family transcriptional regulator compare
JDDGAC_03645 tam -1.8 -1.6 trans-aconitate 2-methyltransferase compare
JDDGAC_06565 ybcN -1.8 -0.8 Uncharacterized protein YbcN compare
JDDGAC_28175 -1.7 -1.0 transcription factor compare
JDDGAC_18405 mnmG -1.7 -2.7 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_11975 -1.7 -2.7 Lon protease compare
JDDGAC_28935 -1.7 -2.0 sialate O-acetylesterase compare
JDDGAC_06425 -1.7 -1.3 phage minor tail protein L compare
JDDGAC_28890 -1.7 -1.4 Serine/threonine-protein phosphatase compare
JDDGAC_04370 rri1 -1.7 -2.0 phage tail protein compare
JDDGAC_23195 sdhE -1.7 -1.7 FAD assembly factor SdhE compare
JDDGAC_00155 hprS -1.6 -1.3 two-component system sensor histidine kinase HprS compare
JDDGAC_14420 surA -1.6 -3.5 peptidylprolyl isomerase SurA compare
JDDGAC_28615 hisB -1.6 -2.2 bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB compare
JDDGAC_13950 pcnB -1.6 -2.7 polynucleotide adenylyltransferase PcnB compare
JDDGAC_03230 -1.6 -1.2 Ead/Ea22-like protein compare
JDDGAC_13155 -1.6 -2.1 phage portal protein compare
JDDGAC_10460 tolB -1.6 -3.7 Tol-Pal system protein TolB compare
JDDGAC_28625 hisD -1.6 -4.0 Histidinol dehydrogenase compare
JDDGAC_01225 yeaQ -1.6 -0.9 UPF0410 protein YeaQ compare
JDDGAC_01040 prc -1.5 -6.2 carboxy terminal-processing peptidase compare
JDDGAC_24165 hosA -1.5 -1.9 Transcriptional regulator HosA compare
JDDGAC_12160 tgt -1.5 -3.4 tRNA guanosine(34) transglycosylase Tgt compare
JDDGAC_00285 fliI -1.5 -1.9 flagellum-specific ATP synthase FliI compare
JDDGAC_05780 -1.5 -1.8 hypothetical protein compare
JDDGAC_11375 -1.4 -0.8 hypothetical protein compare
JDDGAC_05500 -1.4 -1.9 hypothetical protein compare
JDDGAC_00840 ruvC -1.4 -2.7 crossover junction endodeoxyribonuclease RuvC compare
JDDGAC_08140 eAL -1.4 -1.1 EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) compare
JDDGAC_05645 -1.4 -1.4 tRNA-Xxx compare
JDDGAC_24675 -1.4 -0.6 hypothetical protein compare
JDDGAC_00460 -1.4 -1.7 phage tail protein compare
JDDGAC_02475 dnaC -1.4 -1.6 DNA replication protein DnaC compare
JDDGAC_02120 rsxE -1.4 -1.9 electron transport complex subunit RsxE compare
JDDGAC_07345 flgM -1.4 -0.8 anti-sigma-28 factor FlgM compare
JDDGAC_06075 chaB -1.4 -1.2 putative cation transport regulator ChaB compare
JDDGAC_29030 -1.4 -1.6 Putative prophage portal protein compare
JDDGAC_12935 -1.4 -1.7 hypothetical protein compare
JDDGAC_00520 -1.4 -2.3 Phage protein compare
JDDGAC_11835 rsmS -1.4 -0.8 pleiotropic regulatory protein RsmS compare
JDDGAC_08145 dgcT -1.3 -1.3 putative diguanylate cyclase DgcT compare
JDDGAC_18020 corA -1.3 -1.9 magnesium/cobalt transporter CorA compare
JDDGAC_27425 yeiL -1.3 -0.8 Regulatory protein YeiL compare
JDDGAC_06165 ychF -1.3 -1.4 redox-regulated ATPase YchF compare
JDDGAC_00675 flhD -1.3 -1.7 flagellar transcriptional regulator FlhD compare
JDDGAC_24735 rrrD -1.3 -0.8 lysozyme compare
JDDGAC_19185 rpoZ -1.3 -0.7 DNA-directed RNA polymerase subunit omega compare
JDDGAC_20740 aroK -1.3 -1.1 shikimate kinase AroK compare
JDDGAC_01440 ynjD -1.3 -1.0 Uncharacterized ABC transporter ATP-binding protein YnjD compare
JDDGAC_11240 fepG -1.3 -2.0 iron-enterobactin ABC transporter permease compare
JDDGAC_20700 igaA -1.3 -1.4 intracellular growth attenuator protein IgaA compare
JDDGAC_06515 -1.3 -1.1 DUF1398 domain-containing protein compare
JDDGAC_24880 aroF -1.3 -3.1 3-deoxy-7-phosphoheptulonate synthase AroF compare
JDDGAC_21770 nlpI -1.3 -6.5 lipoprotein NlpI compare
JDDGAC_30180 repA2 -1.3 -4.1 Replication regulatory protein repA2 compare
JDDGAC_04080 hicA -1.3 -1.0 type II toxin-antitoxin system mRNA interferase toxin HicA compare
JDDGAC_07740 terZ -1.3 -2.8 tellurium resistance-associated protein TerZ compare
JDDGAC_08995 aspC -1.3 -1.3 aspartate transaminase compare
JDDGAC_17215 argE -1.3 -5.8 acetylornithine deacetylase compare
JDDGAC_26150 cysK -1.3 -6.0 cysteine synthase A compare
JDDGAC_18275 ilvG -1.3 -5.4 acetolactate synthase 2 catalytic subunit compare
JDDGAC_23725 argA -1.3 -4.5 amino-acid N-acetyltransferase compare
JDDGAC_23980 ygcW -1.3 -1.5 Uncharacterized oxidoreductase YgcW compare
JDDGAC_11805 recR -1.3 -1.9 recombination mediator RecR compare
JDDGAC_17795 dsbA -1.2 -3.6 thiol:disulfide interchange protein DsbA compare
JDDGAC_10390 gpmA -1.2 -2.8 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
JDDGAC_01515 cho -1.2 -2.0 excinuclease Cho compare
JDDGAC_06695 -1.2 -2.8 DNA primase compare
JDDGAC_04795 ynaJ -1.2 -2.2 Uncharacterized protein YnaJ compare
JDDGAC_03800 dosP -1.2 -1.0 oxygen-sensing cyclic-di-GMP phosphodiesterase compare
JDDGAC_23110 -1.2 -0.9 Type I toxin-antitoxin system Ibs family toxin compare
JDDGAC_13295 proA -1.2 -4.9 glutamate-5-semialdehyde dehydrogenase compare
JDDGAC_19120 tnp-IS3 -1.2 -0.8 IS3 family transposase compare
JDDGAC_28930 iraM -1.2 -2.3 Anti-adapter protein IraM compare
JDDGAC_11035 lipB -1.2 -0.8 lipoyl(octanoyl) transferase LipB compare
JDDGAC_25980 eutM -1.2 -1.2 ethanolamine utilization microcompartment protein EutM compare
JDDGAC_06025 narJ -1.2 -0.6 nitrate reductase molybdenum cofactor assembly chaperone compare
JDDGAC_25525 -1.2 -0.8 hypothetical protein compare
JDDGAC_15540 treC -1.2 -2.5 alpha,alpha-phosphotrehalase compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in no phage control experiments

For no phage control No phage across organisms