Experiment set4S445 for Escherichia coli ECRC98

Compare to:

WM_Bas41

200 most important genes:

  gene name fitness t score description  
JDDGAC_28590 wzzB -7.7 -5.4 LPS O-antigen chain length determinant protein WzzB compare
JDDGAC_19310 rfaL -6.4 -4.4 O-antigen ligase RfaL compare
JDDGAC_17890 rfaH -6.1 -3.4 transcription/translation regulatory transformer protein RfaH compare
JDDGAC_28575 perB -6.1 -4.1 GDP-perosamine N-acetyltransferase compare
JDDGAC_21455 sspA -5.9 -8.1 stringent starvation protein A compare
JDDGAC_19305 rfaB -5.7 -5.6 UDP-glucose--(glucosyl)LPS alpha-1,2-glucosyltransferase compare
JDDGAC_28510 -5.5 -9.8 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,o ctacis-undecaprenol 4-epimerase compare
JDDGAC_28525 wzy -5.4 -2.9 O157 family O-antigen polymerase compare
JDDGAC_18205 wecA -5.3 -14.6 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase compare
JDDGAC_28540 rfbE -5.3 -2.6 GDP-perosamine synthase RfbE/PerA compare
JDDGAC_19300 rfaJ -5.2 -5.8 glucosyltransferase compare
JDDGAC_26340 ypdK -5.1 -1.5 membrane protein YpdK compare
JDDGAC_10355 acrZ -5.1 -1.4 multidrug efflux pump accessory protein AcrZ compare
JDDGAC_20740 aroK -4.9 -3.4 shikimate kinase AroK compare
JDDGAC_21580 lptC -4.6 -1.6 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_15900 miaA -4.5 -2.5 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
JDDGAC_28560 wbdQ -4.5 -2.2 GDP-mannose mannosyl hydrolase WbdQ/WbhG compare
JDDGAC_22885 yggS -4.4 -6.3 pyridoxal phosphate homeostasis protein compare
JDDGAC_07825 -4.4 -1.3 Membrane protein compare
JDDGAC_03180 -4.3 -2.3 replication protein compare
JDDGAC_28520 wcaA -4.3 -1.8 glycosyl transferase compare
JDDGAC_06305 minE -4.3 -1.2 cell division topological specificity factor MinE compare
JDDGAC_27045 -4.3 -1.2 hypothetical protein compare
JDDGAC_29165 -4.3 -1.2 toxin of the YeeV-YeeU toxin-antitoxin system compare
JDDGAC_15250 -4.2 -1.2 Orf compare
JDDGAC_18185 rffG -4.0 -10.5 dTDP-glucose 4,6-dehydratase compare
JDDGAC_23140 ygfB -4.0 -2.7 UPF0149 family protein YgfB compare
JDDGAC_10285 -4.0 -1.1 Cell division protein ZapA compare
JDDGAC_25045 rseA -3.9 -5.1 anti-sigma-E factor RseA compare
JDDGAC_06295 minC -3.8 -2.5 septum site-determining protein MinC compare
JDDGAC_02145 rsxA -3.8 -1.5 electron transport complex subunit RsxA compare
JDDGAC_06140 ispE -3.7 -1.5 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase compare
JDDGAC_15050 -3.6 -1.4 Putative transposase, YhgA-like compare
JDDGAC_15395 -3.6 -1.4 XRE family transcriptional regulator compare
JDDGAC_05645 -3.5 -2.0 tRNA-Xxx compare
JDDGAC_04130 ydcH -3.4 -1.4 Uncharacterized protein YdcH compare
JDDGAC_15870 purA -3.4 -3.3 adenylosuccinate synthase compare
JDDGAC_18180 rfbA -3.3 -6.4 glucose-1-phosphate thymidylyltransferase RfbA compare
JDDGAC_02170 add -3.3 -1.6 adenosine deaminase compare
JDDGAC_29425 -3.2 -1.3 Prophage protein compare
JDDGAC_07260 yceD -3.2 -2.1 23S rRNA accumulation protein YceD compare
JDDGAC_18020 corA -3.1 -4.2 magnesium/cobalt transporter CorA compare
JDDGAC_03315 -3.0 -1.1 hypothetical protein compare
JDDGAC_08140 eAL -2.9 -2.7 EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) compare
JDDGAC_26875 elaD -2.9 -1.8 ElaD/SseL family deubiquitinase compare
JDDGAC_28935 -2.8 -3.0 sialate O-acetylesterase compare
JDDGAC_06300 minD -2.8 -1.9 septum site-determining protein MinD compare
JDDGAC_26635 -2.7 -5.9 Protein DedA compare
JDDGAC_04540 -2.7 -2.3 ORF6N domain-containing protein compare
JDDGAC_00825 nudB -2.7 -1.0 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_27870 -2.6 -2.1 terminase compare
JDDGAC_02485 -2.6 -2.1 DUF977 domain-containing protein compare
JDDGAC_06145 prs -2.5 -2.4 ribose-phosphate diphosphokinase compare
JDDGAC_26215 -2.5 -0.9 RNA-guided endonuclease TnpB family protein compare
JDDGAC_24800 rnfH -2.5 -3.5 RnfH family protein compare
JDDGAC_27740 -2.4 -1.2 regulator compare
JDDGAC_13010 -2.4 -1.3 Phage-associated protein compare
JDDGAC_14270 rsmH -2.4 -1.3 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH compare
JDDGAC_19285 rfaP -2.3 -3.4 lipopolysaccharide core heptose(I) kinase RfaP compare
JDDGAC_06670 -2.3 -2.7 hypothetical protein compare
JDDGAC_22545 ftsP -2.3 -2.0 cell division protein FtsP compare
JDDGAC_00545 marR -2.3 -1.9 MarR family transcriptional regulator compare
JDDGAC_14795 serB -2.3 -3.1 phosphoserine phosphatase compare
JDDGAC_03335 -2.3 -1.2 9-O-acetyl-N-acetylneuraminic acid deacetylase compare
JDDGAC_15525 mgtL -2.3 -1.3 mgtA leader peptide compare
JDDGAC_05885 yciC -2.3 -1.8 envelope biogenesis factor ElyC compare
JDDGAC_22880 yggT -2.2 -1.2 osmotic shock tolerance protein YggT compare
JDDGAC_19320 rfaF -2.2 -1.9 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_06675 -2.2 -1.4 hypothetical protein compare
JDDGAC_06310 -2.2 -1.3 autotransporter outer membrane beta-barrel domain-containing protein compare
JDDGAC_11975 -2.2 -2.9 Lon protease compare
JDDGAC_06555 ybcO -2.1 -0.8 Putative nuclease YbcO compare
JDDGAC_00525 -2.1 -2.4 derepression protein compare
JDDGAC_23100 serA -2.1 -5.0 phosphoglycerate dehydrogenase compare
JDDGAC_01815 ydiH -2.1 -1.3 Uncharacterized protein YdiH compare
JDDGAC_01585 ybcI -2.1 -2.7 metal-dependent hydrolase compare
JDDGAC_03670 lsrC -2.1 -1.5 autoinducer 2 ABC transporter permease LsrC compare
JDDGAC_29975 sopA -2.1 -3.9 plasmid-partitioning protein SopA compare
JDDGAC_02375 ynfC -2.1 -1.8 YnfC family lipoprotein compare
JDDGAC_09385 lrp -2.0 -2.7 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_09100 serC -2.0 -6.2 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_28515 galF -2.0 -3.3 UTP--glucose-1-phosphate uridylyltransferase GalF compare
JDDGAC_18175 rffC -2.0 -5.0 dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase compare
JDDGAC_10205 -2.0 -1.2 Putative bacteriophage protein (Gene 65) compare
JDDGAC_19100 -2.0 -1.0 Aec79 compare
JDDGAC_14890 holD -2.0 -0.8 DNA polymerase III subunit psi compare
JDDGAC_10815 nagA -2.0 -3.3 N-acetylglucosamine-6-phosphate deacetylase compare
JDDGAC_09030 cmoM -1.9 -1.2 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
JDDGAC_18760 tisB -1.9 -0.9 Small toxic protein TisB compare
JDDGAC_29305 ycdB -1.9 -1.9 putative transcriptional regulatory protein YcdB compare
JDDGAC_07640 -1.9 -1.3 DNA-binding protein compare
JDDGAC_26350 yfdY -1.8 -1.7 Uncharacterized protein YfdY compare
JDDGAC_02140 rsxB -1.8 -1.6 electron transport complex subunit RsxB compare
JDDGAC_22870 rdgB -1.8 -2.2 XTP/dITP diphosphatase compare
JDDGAC_25690 -1.8 -1.5 acyltransferase compare
JDDGAC_08035 lolD -1.8 -1.8 lipoprotein-releasing system ATP-binding protein LolD compare
JDDGAC_05985 galU -1.8 -2.4 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_11365 -1.8 -2.0 Uncharacterized conserved protein compare
JDDGAC_05065 rnb -1.8 -3.6 exoribonuclease II compare
JDDGAC_14595 fimA -1.8 -1.8 fimbrial protein compare
JDDGAC_25435 guaB -1.8 -3.9 IMP dehydrogenase compare
JDDGAC_29120 -1.7 -1.7 phage tail protein compare
JDDGAC_21780 deaD -1.7 -3.8 ATP-dependent RNA helicase DeaD compare
JDDGAC_14865 ytjA -1.7 -0.8 UPF0391 membrane protein YtjA compare
JDDGAC_13000 -1.7 -1.1 AAA family ATPase compare
JDDGAC_16935 purH -1.7 -7.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_10470 tolR -1.7 -4.2 colicin uptake protein TolR compare
JDDGAC_14760 trpR -1.7 -0.8 trp operon repressor compare
JDDGAC_18170 rffA -1.7 -3.0 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
JDDGAC_02410 dnaQ -1.7 -1.3 exonuclease compare
JDDGAC_16940 purD -1.6 -5.1 Phosphoribosylamine--glycine ligase compare
JDDGAC_14430 rsmA -1.6 -1.3 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA compare
JDDGAC_27665 -1.6 -2.0 DUF551 domain-containing protein compare
JDDGAC_01890 -1.6 -2.1 Uncharacterized ferredoxin-like protein YdhX compare
JDDGAC_28760 kil -1.6 -1.1 Protein kil compare
JDDGAC_10455 pal -1.6 -1.3 peptidoglycan-associated lipoprotein Pal compare
JDDGAC_14610 -1.6 -1.1 hypothetical protein compare
JDDGAC_26765 yfbV -1.6 -0.9 UPF0208 membrane protein YfbV compare
JDDGAC_18405 mnmG -1.6 -2.3 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_19075 espF -1.6 -1.7 type III secretion system LEE effector EspF compare
JDDGAC_03900 espR1 -1.6 -1.8 T3SS effector leucine-rich repeat protein EspR1 compare
JDDGAC_25755 purM -1.6 -5.4 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_13290 Thr_trna -1.5 -1.9 tRNA-Thr(cgt) compare
JDDGAC_06230 fadR -1.5 -1.6 fatty acid metabolism transcriptional regulator FadR compare
JDDGAC_25135 purL -1.5 -7.5 phosphoribosylformylglycinamidine synthase compare
JDDGAC_15540 treC -1.5 -3.9 alpha,alpha-phosphotrehalase compare
JDDGAC_26085 murQ -1.5 -3.0 N-acetylmuramic acid 6-phosphate etherase compare
JDDGAC_13015 -1.5 -1.7 Phage-associated protein compare
JDDGAC_06180 -1.5 -1.6 PTS-dependent dihydroxyacetone kinase compare
JDDGAC_06520 bor -1.5 -0.7 serum resistance lipoprotein Bor compare
JDDGAC_09900 ybiE -1.5 -1.8 Protein YbiE compare
JDDGAC_06275 ycgL -1.5 -1.1 Protein YcgL compare
JDDGAC_03615 yneJ -1.5 -1.6 Uncharacterized HTH-type transcriptional regulator YneJ compare
JDDGAC_24045 cysH -1.5 -4.7 phosphoadenosine phosphosulfate reductase compare
JDDGAC_23565 -1.5 -0.8 hypothetical protein compare
JDDGAC_07675 -1.5 -1.1 Oligogalacturonate-specific porin protein KdgM compare
JDDGAC_12935 -1.5 -1.8 hypothetical protein compare
JDDGAC_25440 guaA -1.5 -1.5 glutamine-hydrolyzing GMP synthase compare
JDDGAC_01245 yeaO -1.5 -0.9 Uncharacterized protein YeaO compare
JDDGAC_06425 -1.4 -1.1 phage minor tail protein L compare
JDDGAC_09920 espX2 -1.4 -0.9 type III secretion system effector EspX2 compare
JDDGAC_04820 -1.4 -1.5 Peptidase-S15 domain-containing protein compare
JDDGAC_18960 sepD -1.4 -1.2 type III secretion system LEE switch protein SepD compare
JDDGAC_11490 purK -1.4 -5.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_06155 ychH -1.4 -1.7 stress-induced protein YchH compare
JDDGAC_05525 -1.4 -0.7 host nuclease inhibitor protein compare
JDDGAC_05735 -1.4 -4.3 phage tail protein compare
JDDGAC_19280 rfaG -1.4 -2.7 Lipopolysaccharide core biosynthesis protein RfaG compare
JDDGAC_27680 -1.4 -1.1 Ead/Ea22-like protein compare
JDDGAC_29980 sopA -1.4 -0.8 plasmid-partitioning protein SopA compare
JDDGAC_02120 rsxE -1.3 -1.9 electron transport complex subunit RsxE compare
JDDGAC_10350 modA -1.3 -1.3 molybdate ABC transporter substrate-binding protein compare
JDDGAC_15000 gmrSD -1.3 -2.3 DUF262 domain-containing protein compare
JDDGAC_28690 -1.3 -1.4 hypothetical protein compare
JDDGAC_13385 dinJ -1.3 -1.1 type II toxin-antitoxin system antitoxin DinJ compare
JDDGAC_02135 rsxC -1.3 -3.1 electron transport complex subunit RsxC compare
JDDGAC_01260 yeaL -1.3 -1.3 UPF0756 membrane protein CKO_01811 compare
JDDGAC_03650 lsrG -1.3 -1.4 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase compare
JDDGAC_12025 cyoC -1.3 -1.7 cytochrome o ubiquinol oxidase subunit III compare
JDDGAC_28880 -1.3 -2.8 DNA-binding protein compare
JDDGAC_07480 -1.3 -1.0 Uncharacterized protein YmdA compare
JDDGAC_28030 -1.3 -2.6 Protein compare
JDDGAC_22090 yhaI -1.3 -2.8 Inner membrane protein YhaI compare
JDDGAC_06825 -1.3 -0.8 phage tail tape measure protein compare
JDDGAC_05110 pgpB -1.3 -3.2 phosphatidylglycerophosphatase B compare
JDDGAC_16955 -1.3 -3.0 zinc resistance-associated protein compare
JDDGAC_16680 yjbJ -1.3 -2.4 UPF0337 protein YjbJ compare
JDDGAC_27790 ylcG -1.3 -1.9 Uncharacterized protein YlcG compare
JDDGAC_05245 espM1 -1.3 -1.0 T3SS effector guanine nucleotide exchange factor EspM1 compare
JDDGAC_08265 wrbA -1.3 -1.6 NAD(P)H:quinone oxidoreductase compare
JDDGAC_13545 -1.3 -2.7 hypothetical protein compare
JDDGAC_26675 purF -1.3 -4.9 amidophosphoribosyltransferase compare
JDDGAC_21325 yhdT -1.3 -1.2 Uncharacterized membrane protein YhdT compare
JDDGAC_03795 dosP -1.2 -1.1 oxygen-sensing cyclic-di-GMP phosphodiesterase compare
JDDGAC_25085 recO -1.2 -2.8 DNA repair protein RecO compare
JDDGAC_28685 -1.2 -1.1 AlpA family transcriptional regulator compare
JDDGAC_28445 wcaE -1.2 -1.0 colanic acid biosynthesis glycosyltransferase WcaE compare
JDDGAC_00640 ftnB -1.2 -1.2 non-heme ferritin-like protein compare
JDDGAC_25415 bamB -1.2 -3.1 outer membrane protein assembly factor BamB compare
JDDGAC_01465 ydjY -1.2 -2.4 Uncharacterized protein YdjY compare
JDDGAC_19355 envC -1.2 -3.1 murein hydrolase activator EnvC compare
JDDGAC_29175 yeeT -1.2 -0.8 Uncharacterized protein YeeT compare
JDDGAC_00900 hexR -1.2 -2.6 DNA-binding transcriptional regulator HexR compare
JDDGAC_28970 -1.2 -0.7 DNA-binding protein compare
JDDGAC_02190 hdhA -1.2 -1.4 7-alpha-hydroxysteroid dehydrogenase compare
JDDGAC_03680 lsrR -1.2 -1.3 transcriptional regulator LsrR compare
JDDGAC_15675 cysQ -1.2 -4.5 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_10070 nleB2 -1.2 -0.9 type III secretion system effector arginine glycosyltransferase NleB2 compare
JDDGAC_01035 proQ -1.2 -2.9 RNA chaperone ProQ compare
JDDGAC_19290 waaO -1.2 -1.4 lipopolysaccharide 3-alpha-galactosyltransferase compare
JDDGAC_08845 ompA -1.2 -3.0 outer membrane protein A compare
JDDGAC_23195 sdhE -1.2 -1.3 FAD assembly factor SdhE compare
JDDGAC_09835 rhtA -1.2 -1.9 threonine/homoserine exporter RhtA compare
JDDGAC_19275 rfaQ -1.2 -3.1 lipopolysaccharide core heptosyltransferase RfaQ compare
JDDGAC_22440 tolC -1.2 -3.6 outer membrane channel protein TolC compare
JDDGAC_06745 potB -1.1 -1.9 spermidine/putrescine ABC transporter permease PotB compare
JDDGAC_04370 rri1 -1.1 -1.4 phage tail protein compare
JDDGAC_25750 purN -1.1 -2.3 phosphoribosylglycinamide formyltransferase compare
JDDGAC_11200 entH -1.1 -2.4 proofreading thioesterase EntH compare
JDDGAC_26485 Arg_trna -1.1 -1.0 tRNA-Arg(cct) compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in phage experiments

For phage Phage across organisms