Experiment set4IT091 for Escherichia coli BW25113

Compare to:

LB with octanol 0.08 vol%

200 most important genes:

  gene name fitness t score description  
b1111 ycfQ -7.2 -2.6 orf, hypothetical protein (VIMSS) compare
b1130 phoP -6.8 -4.7 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b1855 lpxM -6.4 -3.7 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2617 smpA -6.4 -2.6 small membrane protein A (VIMSS) compare
b0436 tig -6.3 -7.5 trigger factor (NCBI) compare
b0462 acrB -6.3 -12.7 multidrug efflux system protein (NCBI) compare
b1129 phoQ -6.2 -7.4 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1677 lpp -6.2 -2.3 murein lipoprotein (NCBI) compare
b2808 gcvA -6.2 -4.3 DNA-binding transcriptional dual regulator (NCBI) compare
b3627 rfaI -6.2 -10.3 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b0463 acrA -6.1 -8.4 multidrug efflux system (NCBI) compare
b0178 hlpA -6.0 -2.9 periplasmic chaperone (NCBI) compare
b3625 rfaY -6.0 -7.2 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1604 ydgH -6.0 -3.5 hypothetical protein (NCBI) compare
b0957 ompA -6.0 -3.1 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3628 rfaB -5.9 -9.9 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b3794 rffM -5.9 -4.1 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2784 relA -5.8 -8.0 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b3784 rfe -5.8 -7.9 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3198 kdsC -5.7 -3.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3194 yrbE -5.7 -11.5 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0759 galE -5.7 -5.5 UDP-galactose-4-epimerase (VIMSS) compare
b1531 marA -5.7 -2.4 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b2969 yghE -5.6 -2.9 predicted secretion pathway protein, L-type protein (pseudogene) (RefSeq) compare
b3632 rfaQ -5.6 -15.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1524 yneH -5.5 -1.0 predicted glutaminase (NCBI) compare
b2317 dedA -5.5 -4.0 conserved inner membrane protein (NCBI) compare
b2512 yfgL -5.5 -3.8 protein assembly complex, lipoprotein component (NCBI) compare
b3199 yrbK -5.5 -2.0 hypothetical protein (NCBI) compare
b3787 rffD -5.5 -9.2 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b3035 tolC -5.5 -7.5 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b4695 ykgT -5.4 -1.7 no description compare
b3644 yicC -5.4 -5.3 hypothetical protein (NCBI) compare
b2501 ppk -5.4 -9.0 polyphosphate kinase (NCBI) compare
b2450 yffS -5.4 -1.7 CPZ-55 prophage; predicted protein (RefSeq) compare
b3195 yrbF -5.4 -13.0 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0471 ybaB -5.4 -3.0 hypothetical protein (NCBI) compare
b3107 yhaL -5.3 -1.0 orf, hypothetical protein (VIMSS) compare
b3192 yrbC -5.3 -10.8 predicted ABC-type organic solvent transporter (NCBI) compare
b3931 hslU -5.3 -18.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3193 yrbD -5.3 -10.4 predicted ABC-type organic solvent transporter (NCBI) compare
b0683 fur -5.3 -1.7 ferric uptake regulator (NCBI) compare
b3163 nlpI -5.2 -3.6 hypothetical protein (NCBI) compare
b3631 rfaG -5.2 -11.2 glucosyltransferase I (NCBI) compare
b0617 citD -5.1 -1.9 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b4396 rob -5.1 -11.7 DNA-binding transcriptional activator (NCBI) compare
b3786 rffE -5.1 -11.8 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b2531 iscR -5.0 -1.6 DNA-binding transcriptional repressor (NCBI) compare
b1765 ydjA -5.0 -0.9 predicted oxidoreductase (NCBI) compare
b3630 rfaP -5.0 -4.9 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1830 prc -5.0 -3.5 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3398 yrfF -5.0 -2.9 predicted inner membrane protein (NCBI) compare
b0814 ompX -4.9 -5.4 outer membrane protein X (NCBI) compare
b2174 b2174 -4.9 -8.0 orf, hypothetical protein (VIMSS) compare
b0866 ybjQ -4.9 -0.9 hypothetical protein (NCBI) compare
b0014 dnaK -4.8 -2.0 molecular chaperone DnaK (NCBI) compare
b0737 tolQ -4.8 -3.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1236 galU -4.8 -4.6 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0740 tolB -4.7 -4.6 translocation protein TolB precursor (NCBI) compare
b2346 vacJ -4.7 -8.2 predicted lipoprotein (NCBI) compare
b0406 tgt -4.7 -8.0 queuine tRNA-ribosyltransferase (NCBI) compare
b4585 sroB -4.7 -0.9 Novel sRNA, function unknown (RefSeq) compare
b0739 tolA -4.7 -3.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4529 ydbJ -4.7 -0.9 hypothetical protein (NCBI) compare
b3082 ygjM -4.7 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b4443 gcvB -4.7 -1.5 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b0741 pal -4.7 -3.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1058 yceO -4.7 -1.2 hypothetical protein (NCBI) compare
b3005 exbD -4.7 -5.8 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3842 rfaH -4.7 -3.2 transcriptional activator RfaH (NCBI) compare
b4480 hdfR -4.6 -5.8 transcriptional regulator HdfR (NCBI) compare
b1642 slyA -4.6 -1.2 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b0688 pgm -4.6 -3.2 phosphoglucomutase (NCBI) compare
b2576 srmB -4.6 -3.2 ATP-dependent RNA helicase (NCBI) compare
b3778 rep -4.5 -8.1 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2620 smpB -4.5 -2.0 SsrA-binding protein (NCBI) compare
b1252 tonB -4.4 -4.1 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b0441 ppiD -4.4 -13.2 peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI) compare
b3026 qseC -4.4 -5.2 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3728 pstS -4.4 -3.0 phosphate transporter subunit (NCBI) compare
b1358 ydaT -4.4 -1.1 Rac prophage; predicted protein (NCBI) compare
b0764 modB -4.3 -5.1 molybdate ABC transporter permease protein (NCBI) compare
b3052 rfaE -4.3 -3.0 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3191 yrbB -4.3 -10.2 orf, hypothetical protein (VIMSS) compare
b4042 dgkA -4.3 -3.6 diacylglycerol kinase (NCBI) compare
b0549 ybcO -4.2 -1.6 DLP12 prophage; predicted protein (NCBI) compare
b3150 yraP -4.2 -7.1 hypothetical protein (NCBI) compare
b3207 yrbL -4.2 -6.3 hypothetical protein (NCBI) compare
b0222 lpcA -4.2 -2.3 phosphoheptose isomerase (NCBI) compare
b4146 yjeK -4.1 -2.9 predicted lysine aminomutase (NCBI) compare
b0082 mraW -4.1 -4.6 S-adenosyl-methyltransferase (NCBI) compare
b2363 yfdT -4.1 -3.1 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3916 pfkA -4.1 -4.9 6-phosphofructokinase (NCBI) compare
b4375 prfC -4.1 -8.8 peptide chain release factor 3 (NCBI) compare
b0145 dksA -4.1 -4.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3229 sspA -4.1 -4.0 stringent starvation protein A (NCBI) compare
b2906 visC -4.1 -8.7 hypothetical protein (NCBI) compare
b1144 ymfJ -4.1 -1.8 orf, hypothetical protein (VIMSS) compare
b0560 nohB -4.0 -2.1 DLP12 prophage; DNA packaging protein (NCBI) compare
b1684 sufA -3.9 -1.9 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b3764 yifE -3.9 -5.0 hypothetical protein (NCBI) compare
b0738 tolR -3.8 -3.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0440 hupB -3.8 -4.9 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b1400 paaY -3.8 -2.3 predicted hexapeptide repeat acetyltransferase (NCBI) compare
b3261 fis -3.8 -2.6 DNA-binding protein Fis (NCBI) compare
b4436 ryeC -3.7 -1.0 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b3726 pstA -3.7 -6.8 phosphate transporter subunit (NCBI) compare
b2188 yejM -3.7 -8.5 predicted hydrolase, inner membrane (NCBI) compare
b3621 rfaC -3.7 -3.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b4418 sraB -3.7 -0.9 unknown RNA (NCBI) compare
b4481 rffT -3.6 -6.9 4-alpha-L-fucosyltransferase (NCBI) compare
b3620 rfaF -3.6 -2.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1138 ymfE -3.6 -0.9 e14 prophage; predicted inner membrane protein (NCBI) compare
b0059 hepA -3.6 -12.1 ATP-dependent helicase HepA (NCBI) compare
b3619 rfaD -3.6 -2.5 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3183 obgE -3.6 -1.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4441 glmY -3.6 -0.9 sRNA activator of glmS mRNA (RefSeq) compare
b0053 surA -3.6 -3.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b4416 rybA -3.6 -0.9 unknown RNA (NCBI) compare
b2567 rnc -3.6 -1.5 ribonuclease III (NCBI) compare
b2477 nlpB -3.5 -3.4 lipoprotein-34 (VIMSS) compare
b3463 ftsE -3.5 -4.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3725 pstB -3.5 -2.4 phosphate transporter subunit (NCBI) compare
b1658 purR -3.5 -5.9 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2181 yejG -3.5 -3.9 hypothetical protein (NCBI) compare
b3363 ppiA -3.4 -7.7 peptidyl-prolyl cis-trans isomerase A (rotamase A) (NCBI) compare
b0623 cspE -3.4 -1.5 cold shock protein E (NCBI) compare
b3029 ygiN -3.4 -2.3 quinol monooxygenase (NCBI) compare
b1709 btuD -3.4 -0.9 vitamin B12-transporter ATPase (NCBI) compare
b3791 rffA -3.4 -7.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1693 aroD -3.4 -5.2 3-dehydroquinate dehydratase (NCBI) compare
b2553 glnB -3.3 -4.6 regulatory protein P-II for glutamine synthetase (NCBI) compare
b0630 lipB -3.3 -2.4 protein of lipoate biosynthesis (VIMSS) compare
b0232 yafN -3.3 -0.9 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1126 potA -3.3 -7.7 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b1712 ihfA -3.2 -2.7 integration host factor subunit alpha (NCBI) compare
b2330 yfcB -3.2 -2.6 putative adenine-specific methylase (VIMSS) compare
b1831 proQ -3.2 -2.6 putative solute/DNA competence effector (NCBI) compare
b0101 yacG -3.1 -2.7 zinc-binding protein (NCBI) compare
b2494 yfgC -3.1 -6.4 predicted peptidase (NCBI) compare
b1676 pykF -3.1 -4.3 pyruvate kinase (NCBI) compare
b4172 hfq -3.1 -1.9 RNA-binding protein Hfq (NCBI) compare
b1984 asnW -3.1 -0.8 tRNA-Asn (NCBI) compare
b1286 rnb -3.1 -3.6 exoribonuclease II (NCBI) compare
b1085 b1085 -3.1 -1.6 orf, hypothetical protein (VIMSS) compare
b3790 rffC -3.1 -4.4 TDP-fucosamine acetyltransferase (RefSeq) compare
b0200 gmhB -3.1 -1.6 hypothetical protein (NCBI) compare
b4453 ldrD -3.1 -1.5 toxic polypeptide, small (NCBI) compare
b3870 glnA -3.0 -2.1 glutamine synthetase (NCBI) compare
b4155 yjeA -3.0 -1.7 putative lysyl-tRNA synthetase (VIMSS) compare
b4699 fnrS -3.0 -0.8 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b4598 yncL -3.0 -1.2 hypothetical protein (RefSeq) compare
b2572 rseA -2.9 -3.1 anti-sigma factor (NCBI) compare
b1961 dcm -2.9 -1.3 DNA cytosine methylase (NCBI) compare
b0627 tatE -2.9 -1.9 twin arginine translocase protein E (NCBI) compare
b3162 deaD -2.8 -7.7 inducible ATP-independent RNA helicase (VIMSS) compare
b4000 hupA -2.8 -3.2 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b3100 yqjK -2.8 -2.7 hypothetical protein (NCBI) compare
b1834 yebT -2.8 -4.9 orf, hypothetical protein (VIMSS) compare
b0890 ftsK -2.7 -10.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3389 aroB -2.7 -7.0 3-dehydroquinate synthase (NCBI) compare
b4435 isrC -2.7 -1.3 unknown RNA (NCBI) compare
b3839 tatC -2.7 -8.2 TatABCE protein translocation system subunit (NCBI) compare
b0950 pqiA -2.7 -4.6 paraquat-inducible membrane protein A (NCBI) compare
b1293 sapB -2.7 -1.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1123 potD -2.7 -5.1 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b4648 ysaC -2.6 -2.3 no description compare
b0092 ddlB -2.6 -4.6 D-alanylalanine synthetase (NCBI) compare
b4515 ybgT -2.6 -1.0 hypothetical protein (NCBI) compare
b0430 cyoC -2.6 -3.8 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b3386 rpe -2.6 -1.7 ribulose-phosphate 3-epimerase (NCBI) compare
b3237 argR -2.6 -4.9 arginine repressor (NCBI) compare
b1853 yebK -2.6 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b3932 hslV -2.6 -5.9 ATP-dependent protease peptidase subunit (NCBI) compare
b0677 nagA -2.6 -3.8 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b4025 pgi -2.6 -6.7 glucose-6-phosphate isomerase (NCBI) compare
b2189 proL -2.6 -1.3 tRNA-Pro (NCBI) compare
b1591 b1591 -2.5 -1.2 putative oxidoreductase component (VIMSS) compare
b2518 ndk -2.5 -2.5 nucleoside diphosphate kinase (NCBI) compare
b3609 secB -2.5 -2.6 export protein SecB (NCBI) compare
b2064 asmA -2.5 -6.4 predicted assembly protein (NCBI) compare
b3290 trkA -2.5 -5.0 potassium transporter peripheral membrane component (NCBI) compare
b4698 mgrR -2.5 -1.9 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b4511 ybdZ -2.5 -1.8 hypothetical protein (NCBI) compare
b3006 exbB -2.5 -4.9 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3426 glpD -2.4 -6.0 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0118 acnB -2.4 -5.8 aconitate hydratase (NCBI) compare
b2820 recB -2.4 -3.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3636 rpmG -2.4 -1.1 50S ribosomal protein L33 (NCBI) compare
b3727 pstC -2.4 -7.5 phosphate transporter subunit (NCBI) compare
b1811 yoaH -2.4 -2.3 hypothetical protein (NCBI) compare
b1266 yciV -2.4 -2.1 hypothetical protein (NCBI) compare
b1960 vsr -2.4 -2.7 DNA mismatch endonuclease of very short patch repair (NCBI) compare
b4484 cpxP -2.3 -3.4 periplasmic protein combats stress (NCBI) compare
b0783 moaC -2.3 -3.6 molybdenum cofactor biosynthesis protein C (NCBI) compare
b3281 aroE -2.3 -7.6 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1124 potC -2.3 -4.1 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4577 sgrS -2.2 -1.2 small antisense RNA (NCBI) compare
b0049 apaH -2.2 -4.0 diadenosinetetraphosphatase (NCBI) compare
b1348 lar -2.1 -2.9 Rac prophage; restriction alleviation protein (NCBI) compare


Specific Phenotypes

For 27 genes in this experiment

For stress octanol in Escherichia coli BW25113

For stress octanol across organisms