Experiment set4IT084 for Escherichia coli BW25113

Compare to:

LB with hexanol 0.31 vol%

200 most important genes:

  gene name fitness t score description  
b1095 fabF -5.8 -9.7 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b4042 dgkA -5.4 -3.8 diacylglycerol kinase (NCBI) compare
b0222 lpcA -5.2 -3.6 phosphoheptose isomerase (NCBI) compare
b0018 mokC -5.1 -2.1 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b3631 rfaG -5.0 -22.3 glucosyltransferase I (NCBI) compare
b1236 galU -4.9 -8.2 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3052 rfaE -4.9 -5.8 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0739 tolA -4.8 -5.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3463 ftsE -4.6 -4.5 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3842 rfaH -4.5 -6.9 transcriptional activator RfaH (NCBI) compare
b3619 rfaD -4.5 -4.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0630 lipB -4.4 -3.1 protein of lipoate biosynthesis (VIMSS) compare
b3621 rfaC -4.4 -5.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3630 rfaP -4.3 -18.0 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3931 hslU -4.3 -15.6 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3035 tolC -4.3 -12.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3839 tatC -4.3 -13.7 TatABCE protein translocation system subunit (NCBI) compare
b0053 surA -4.3 -4.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0200 gmhB -4.2 -2.9 hypothetical protein (NCBI) compare
b3620 rfaF -4.2 -4.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0430 cyoC -4.2 -6.4 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b0014 dnaK -4.1 -4.2 molecular chaperone DnaK (NCBI) compare
b3398 yrfF -4.1 -5.6 predicted inner membrane protein (NCBI) compare
b2297 pta -4.1 -2.8 phosphate acetyltransferase (NCBI) compare
b0688 pgm -4.1 -4.8 phosphoglucomutase (NCBI) compare
b0740 tolB -4.0 -9.0 translocation protein TolB precursor (NCBI) compare
b0737 tolQ -3.9 -5.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0431 cyoB -3.8 -14.7 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3725 pstB -3.8 -5.8 phosphate transporter subunit (NCBI) compare
b3462 ftsX -3.8 -9.4 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3613 yibP -3.7 -8.4 putative membrane protein (VIMSS) compare
b0114 aceE -3.7 -3.6 pyruvate dehydrogenase subunit E1 (NCBI) compare
b2830 nudH -3.7 -3.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b3609 secB -3.6 -3.9 export protein SecB (NCBI) compare
b4155 yjeA -3.5 -2.4 putative lysyl-tRNA synthetase (VIMSS) compare
b3026 qseC -3.5 -9.3 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3405 ompR -3.2 -7.5 osmolarity response regulator (NCBI) compare
b0428 cyoE -3.1 -8.3 protoheme IX farnesyltransferase (NCBI) compare
b3493 pitA -3.0 -14.4 phosphate transporter, low-affinity (NCBI) compare
b3082 ygjM -3.0 -2.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b0429 cyoD -2.9 -4.1 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b3261 fis -2.9 -5.8 DNA-binding protein Fis (NCBI) compare
b3162 deaD -2.9 -8.8 inducible ATP-independent RNA helicase (VIMSS) compare
b2512 yfgL -2.8 -8.8 protein assembly complex, lipoprotein component (NCBI) compare
b0432 cyoA -2.8 -10.2 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b0957 ompA -2.6 -6.5 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2894 xerD -2.6 -2.5 site-specific tyrosine recombinase XerD (NCBI) compare
b2620 smpB -2.6 -3.0 SsrA-binding protein (NCBI) compare
b1109 ndh -2.6 -5.1 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b0890 ftsK -2.6 -10.1 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3424 glpG -2.5 -7.6 predicted intramembrane serine protease (NCBI) compare
b3465 yhhF -2.5 -6.9 predicted methyltransferase (NCBI) compare
b0738 tolR -2.5 -5.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3150 yraP -2.5 -6.8 hypothetical protein (NCBI) compare
b3290 trkA -2.4 -6.0 potassium transporter peripheral membrane component (NCBI) compare
b3095 yqjA -2.4 -7.8 conserved inner membrane protein (NCBI) compare
b3204 ptsN -2.4 -6.5 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2820 recB -2.4 -5.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2822 recC -2.4 -8.4 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b3932 hslV -2.3 -7.9 ATP-dependent protease peptidase subunit (NCBI) compare
b4146 yjeK -2.2 -4.6 predicted lysine aminomutase (NCBI) compare
b1293 sapB -2.2 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0149 mrcB -2.2 -12.5 penicillin-binding protein 1b (NCBI) compare
b0145 dksA -2.2 -3.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0888 trxB -2.2 -5.2 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4202 rpsR -2.1 -2.9 30S ribosomal protein S18 (NCBI) compare
b3977 tyrU -2.1 -1.4 tRNA-Tyr (NCBI) compare
b1279 yciS -2.1 -1.4 conserved inner membrane protein (NCBI) compare
b2688 gshA -2.1 -8.1 glutamate--cysteine ligase (NCBI) compare
b3627 rfaI -2.0 -13.0 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3628 rfaB -2.0 -12.8 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b1290 sapF -2.0 -3.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0741 pal -1.9 -5.3 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1291 sapD -1.9 -2.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2935 tktA -1.9 -5.2 transketolase 1, thiamin-binding (NCBI) compare
b3838 tatB -1.9 -5.0 sec-independent translocase (NCBI) compare
b2363 yfdT -1.9 -3.2 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b0439 lon -1.8 -6.0 DNA-binding ATP-dependent protease La (NCBI) compare
b2528 iscA -1.8 -2.6 iron-sulfur cluster assembly protein (NCBI) compare
b0881 clpS -1.8 -3.0 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b3979 thrT -1.8 -1.4 tRNA-Thr (NCBI) compare
b3387 dam -1.7 -10.1 DNA adenine methylase (NCBI) compare
b3806 cyaA -1.7 -5.5 adenylate cyclase (NCBI) compare
b3849 trkH -1.7 -9.4 potassium transporter (NCBI) compare
b3781 trxA -1.6 -3.1 thioredoxin 1 (VIMSS) compare
b3414 gntY -1.6 -5.4 predicted gluconate transport associated protein (NCBI) compare
b3811 xerC -1.6 -4.4 site-specific tyrosine recombinase XerC (NCBI) compare
b1143 ymfI -1.6 -1.1 orf, hypothetical protein (VIMSS) compare
b4685 yrbN -1.6 -3.1 expressed protein (RefSeq) compare
b3632 rfaQ -1.6 -12.5 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0232 yafN -1.6 -1.2 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0015 dnaJ -1.5 -7.7 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3390 aroK -1.5 -3.1 shikimate kinase I (NCBI) compare
b2947 gshB -1.5 -3.8 glutathione synthetase (NCBI) compare
b1105 ycfM -1.4 -3.7 predicted outer membrane lipoprotein (NCBI) compare
b0471 ybaB -1.4 -2.6 hypothetical protein (NCBI) compare
b1677 lpp -1.4 -3.3 murein lipoprotein (NCBI) compare
b3183 obgE -1.4 -2.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4413 sokC -1.4 -1.7 regulatory antisense RNA (NCBI) compare
b3836 b3836 -1.4 -2.7 orf, hypothetical protein (VIMSS) compare
b1292 sapC -1.4 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3426 glpD -1.4 -6.7 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0049 apaH -1.4 -5.6 diadenosinetetraphosphatase (NCBI) compare
b3787 rffD -1.3 -7.9 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b3784 rfe -1.3 -8.3 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3652 recG -1.3 -7.4 ATP-dependent DNA helicase (NCBI) compare
b0167 glnD -1.3 -3.9 PII uridylyl-transferase (NCBI) compare
b3786 rffE -1.3 -7.8 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b0726 sucA -1.3 -3.0 alpha-ketoglutarate decarboxylase (NCBI) compare
b3912 cpxR -1.3 -7.2 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b1103 ycfF -1.3 -1.5 orf, hypothetical protein (VIMSS) compare
b3500 gor -1.3 -2.0 glutathione reductase (NCBI) compare
b0437 clpP -1.3 -6.5 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0082 mraW -1.3 -2.9 S-adenosyl-methyltransferase (NCBI) compare
b1977 asnT -1.3 -1.7 tRNA-Asn (NCBI) compare
b4177 purA -1.3 -3.7 adenylosuccinate synthetase (NCBI) compare
b3404 envZ -1.3 -6.1 osmolarity sensor protein (NCBI) compare
b0178 hlpA -1.3 -3.2 periplasmic chaperone (NCBI) compare
b3871 bipA -1.2 -7.7 GTP-binding protein (NCBI) compare
b1709 btuD -1.2 -1.4 vitamin B12-transporter ATPase (NCBI) compare
b1863 ruvC -1.2 -3.4 Holliday junction resolvase (NCBI) compare
b1676 pykF -1.2 -3.9 pyruvate kinase (NCBI) compare
b2614 grpE -1.2 -1.3 heat shock protein (NCBI) compare
b1860 ruvB -1.2 -1.0 Holliday junction DNA helicase B (NCBI) compare
b4239 treC -1.2 -5.1 trehalose-6-P hydrolase (NCBI) compare
b0436 tig -1.2 -5.5 trigger factor (NCBI) compare
b3386 rpe -1.2 -2.5 ribulose-phosphate 3-epimerase (NCBI) compare
b0759 galE -1.2 -6.2 UDP-galactose-4-epimerase (VIMSS) compare
b2330 yfcB -1.2 -2.3 putative adenine-specific methylase (VIMSS) compare
b2617 smpA -1.2 -3.7 small membrane protein A (VIMSS) compare
b3961 oxyR -1.2 -7.3 DNA-binding transcriptional dual regulator (NCBI) compare
b2939 yqgB -1.1 -1.6 predicted protein (RefSeq) compare
b0764 modB -1.1 -4.0 molybdate ABC transporter permease protein (NCBI) compare
b2569 lepA -1.1 -3.3 GTP-binding protein LepA (NCBI) compare
b2340 sixA -1.1 -3.6 phosphohistidine phosphatase (NCBI) compare
b1429 tehA -1.1 -1.5 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4045 yjbJ -1.1 -2.1 predicted stress response protein (NCBI) compare
b3785 wzzE -1.1 -7.0 putative transport protein (VIMSS) compare
b4375 prfC -1.1 -5.6 peptide chain release factor 3 (NCBI) compare
b2215 ompC -1.1 -5.8 outer membrane porin protein C (NCBI) compare
b0912 ihfB -1.1 -3.3 integration host factor subunit beta (NCBI) compare
b1306 pspC -1.1 -2.0 DNA-binding transcriptional activator (NCBI) compare
b1235 rssB -1.1 -5.0 response regulator of RpoS (NCBI) compare
b0814 ompX -1.0 -2.9 outer membrane protein X (NCBI) compare
b1171 b1171 -1.0 -1.5 orf, hypothetical protein (VIMSS) compare
b3098 yqjD -1.0 -2.1 hypothetical protein (NCBI) compare
b3794 rffM -1.0 -4.7 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b4481 rffT -1.0 -3.7 4-alpha-L-fucosyltransferase (NCBI) compare
b2990 hybG -1.0 -1.9 hydrogenase 2 accessory protein (NCBI) compare
b3911 cpxA -1.0 -5.8 two-component sensor protein (NCBI) compare
b1304 pspA -1.0 -2.3 regulatory protein for phage-shock-protein operon (NCBI) compare
b3807 cyaY -1.0 -4.1 frataxin-like protein (NCBI) compare
b2284 nuoF -1.0 -3.7 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1840 yebZ -1.0 -3.0 predicted inner membrane protein (NCBI) compare
b3021 ygiT -1.0 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b2952 yggT -1.0 -3.6 predicted inner membrane protein (NCBI) compare
b4552 yrhC -0.9 -2.2 no description compare
b1841 yobA -0.9 -1.4 hypothetical protein (NCBI) compare
b2277 nuoM -0.9 -3.7 NADH dehydrogenase subunit M (NCBI) compare
b0677 nagA -0.9 -3.6 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1918 yecS -0.9 -1.7 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2513 yfgM -0.9 -2.5 hypothetical protein (NCBI) compare
b0866 ybjQ -0.9 -0.9 hypothetical protein (NCBI) compare
b2938 speA -0.9 -5.4 arginine decarboxylase (NCBI) compare
b2572 rseA -0.9 -2.2 anti-sigma factor (NCBI) compare
b1070 flgN -0.9 -0.9 export chaperone for FlgK and FlgL (NCBI) compare
b1175 minD -0.9 -3.2 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1658 purR -0.8 -4.1 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b1804 rnd -0.8 -3.3 ribonuclease D (NCBI) compare
b2113 mrp -0.8 -3.6 putative ATPase (VIMSS) compare
b1757 b1757 -0.8 -2.4 putative thiosulfate sulfur transferase (VIMSS) compare
b0463 acrA -0.8 -4.7 multidrug efflux system (NCBI) compare
b1831 proQ -0.8 -1.9 putative solute/DNA competence effector (NCBI) compare
b3194 yrbE -0.8 -4.9 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2259 pmrD -0.8 -1.1 polymyxin resistance protein B (VIMSS) compare
b3727 pstC -0.8 -3.3 phosphate transporter subunit (NCBI) compare
b0051 ksgA -0.8 -3.1 dimethyladenosine transferase (NCBI) compare
b0438 clpX -0.8 -3.8 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1752 ydjZ -0.8 -1.6 conserved inner membrane protein (NCBI) compare
b1252 tonB -0.8 -2.1 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b1805 fadD -0.8 -3.9 acyl-CoA synthase (NCBI) compare
b3649 rpoZ -0.8 -2.7 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3616 tdh -0.8 -3.1 L-threonine 3-dehydrogenase (NCBI) compare
b2346 vacJ -0.8 -4.7 predicted lipoprotein (NCBI) compare
b3193 yrbD -0.8 -4.5 predicted ABC-type organic solvent transporter (NCBI) compare
b3857 mobA -0.8 -2.9 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b4529 ydbJ -0.8 -0.7 hypothetical protein (NCBI) compare
b4096 phnL -0.8 -2.2 carbon-phosphorus lyase complex subunit (NCBI) compare
b0226 dinJ -0.8 -1.5 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1187 fadR -0.8 -1.7 fatty acid metabolism regulator (NCBI) compare
b2564 pdxJ -0.8 -1.4 pyridoxal phosphate biosynthetic protein (NCBI) compare
b3169 nusA -0.8 -1.3 transcription elongation factor NusA (NCBI) compare
b0549 ybcO -0.7 -1.7 DLP12 prophage; predicted protein (NCBI) compare
b4062 soxS -0.7 -2.3 DNA-binding transcriptional dual regulator (NCBI) compare
b2531 iscR -0.7 -0.9 DNA-binding transcriptional repressor (NCBI) compare
b0088 murD -0.7 -0.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b0806 ybiM -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b1915 yecF -0.7 -4.3 hypothetical protein (NCBI) compare
b0118 acnB -0.7 -2.2 aconitate hydratase (NCBI) compare
b3146 yraL -0.7 -3.4 predicted methyltransferase (NCBI) compare


Specific Phenotypes

For 5 genes in this experiment

For stress hexanol in Escherichia coli BW25113

For stress hexanol across organisms