Experiment set4IT083 for Escherichia coli BW25113

Compare to:

LB with hexanol 0.31 vol%

200 most important genes:

  gene name fitness t score description  
b3398 yrfF -5.4 -3.7 predicted inner membrane protein (NCBI) compare
b0222 lpcA -5.1 -3.5 phosphoheptose isomerase (NCBI) compare
b3979 thrT -4.8 -2.1 tRNA-Thr (NCBI) compare
b1095 fabF -4.6 -10.8 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3052 rfaE -4.6 -6.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3621 rfaC -4.6 -3.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3609 secB -4.5 -5.0 export protein SecB (NCBI) compare
b3463 ftsE -4.4 -5.2 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0630 lipB -4.4 -3.0 protein of lipoate biosynthesis (VIMSS) compare
b4042 dgkA -4.4 -5.2 diacylglycerol kinase (NCBI) compare
b3631 rfaG -4.4 -23.0 glucosyltransferase I (NCBI) compare
b3630 rfaP -4.3 -17.3 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3619 rfaD -4.2 -5.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0200 gmhB -4.2 -2.9 hypothetical protein (NCBI) compare
b3620 rfaF -4.1 -4.8 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3026 qseC -4.1 -8.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3839 tatC -3.8 -13.3 TatABCE protein translocation system subunit (NCBI) compare
b1236 galU -3.8 -9.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2820 recB -3.8 -4.4 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3842 rfaH -3.7 -8.3 transcriptional activator RfaH (NCBI) compare
b2830 nudH -3.7 -3.5 dinucleoside polyphosphate hydrolase (NCBI) compare
b0053 surA -3.6 -7.3 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3035 tolC -3.4 -10.6 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2297 pta -3.4 -3.3 phosphate acetyltransferase (NCBI) compare
b3613 yibP -3.4 -8.6 putative membrane protein (VIMSS) compare
b3405 ompR -3.3 -8.1 osmolarity response regulator (NCBI) compare
b3162 deaD -3.3 -9.6 inducible ATP-independent RNA helicase (VIMSS) compare
b3725 pstB -3.3 -5.9 phosphate transporter subunit (NCBI) compare
b0114 aceE -3.3 -4.5 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3462 ftsX -3.3 -10.4 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3493 pitA -3.2 -13.7 phosphate transporter, low-affinity (NCBI) compare
b0738 tolR -3.1 -6.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0688 pgm -3.0 -5.7 phosphoglucomutase (NCBI) compare
b3290 trkA -3.0 -6.0 potassium transporter peripheral membrane component (NCBI) compare
b0739 tolA -2.9 -6.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0888 trxB -2.9 -6.2 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3931 hslU -2.9 -10.8 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0740 tolB -2.9 -8.1 translocation protein TolB precursor (NCBI) compare
b0890 ftsK -2.8 -11.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2947 gshB -2.6 -5.7 glutathione synthetase (NCBI) compare
b2688 gshA -2.6 -8.3 glutamate--cysteine ligase (NCBI) compare
b2935 tktA -2.5 -5.9 transketolase 1, thiamin-binding (NCBI) compare
b1290 sapF -2.5 -3.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0145 dksA -2.5 -5.3 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0957 ompA -2.5 -4.6 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b0430 cyoC -2.4 -4.4 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b2512 yfgL -2.4 -6.1 protein assembly complex, lipoprotein component (NCBI) compare
b4585 sroB -2.4 -1.8 Novel sRNA, function unknown (RefSeq) compare
b0428 cyoE -2.4 -7.1 protoheme IX farnesyltransferase (NCBI) compare
b0737 tolQ -2.3 -5.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1293 sapB -2.3 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0431 cyoB -2.3 -10.0 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3386 rpe -2.2 -3.4 ribulose-phosphate 3-epimerase (NCBI) compare
b4177 purA -2.2 -6.5 adenylosuccinate synthetase (NCBI) compare
b1292 sapC -2.2 -3.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0149 mrcB -2.2 -13.1 penicillin-binding protein 1b (NCBI) compare
b2894 xerD -2.2 -2.1 site-specific tyrosine recombinase XerD (NCBI) compare
b3465 yhhF -2.2 -8.4 predicted methyltransferase (NCBI) compare
b0741 pal -2.2 -5.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3095 yqjA -2.2 -7.6 conserved inner membrane protein (NCBI) compare
b0226 dinJ -2.2 -4.0 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b2620 smpB -2.1 -2.7 SsrA-binding protein (NCBI) compare
b3082 ygjM -2.1 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b0014 dnaK -2.1 -3.3 molecular chaperone DnaK (NCBI) compare
b0439 lon -2.1 -7.2 DNA-binding ATP-dependent protease La (NCBI) compare
b0432 cyoA -2.0 -8.8 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3261 fis -2.0 -4.7 DNA-binding protein Fis (NCBI) compare
b3838 tatB -2.0 -6.5 sec-independent translocase (NCBI) compare
b1291 sapD -2.0 -3.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3932 hslV -2.0 -8.1 ATP-dependent protease peptidase subunit (NCBI) compare
b1105 ycfM -1.9 -2.6 predicted outer membrane lipoprotein (NCBI) compare
b0232 yafN -1.9 -1.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3204 ptsN -1.9 -7.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b4685 yrbN -1.8 -3.2 expressed protein (RefSeq) compare
b3806 cyaA -1.8 -6.3 adenylate cyclase (NCBI) compare
b3414 gntY -1.8 -4.6 predicted gluconate transport associated protein (NCBI) compare
b2279 nuoK -1.8 -2.6 NADH dehydrogenase subunit K (NCBI) compare
b0167 glnD -1.8 -5.1 PII uridylyl-transferase (NCBI) compare
b4505 insX -1.8 -2.1 predicted IS protein (RefSeq) compare
b3836 b3836 -1.8 -2.5 orf, hypothetical protein (VIMSS) compare
b3627 rfaI -1.8 -11.5 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3849 trkH -1.7 -10.2 potassium transporter (NCBI) compare
b2822 recC -1.7 -5.9 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4239 treC -1.7 -6.5 trehalose-6-P hydrolase (NCBI) compare
b4146 yjeK -1.7 -4.1 predicted lysine aminomutase (NCBI) compare
b2258 b2258 -1.6 -1.7 putative transport/receptor protein (VIMSS) compare
b4172 hfq -1.6 -2.9 RNA-binding protein Hfq (NCBI) compare
b1109 ndh -1.6 -4.3 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b3424 glpG -1.6 -7.9 predicted intramembrane serine protease (NCBI) compare
b0429 cyoD -1.6 -4.9 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b1591 b1591 -1.6 -1.9 putative oxidoreductase component (VIMSS) compare
b2284 nuoF -1.5 -4.3 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3787 rffD -1.5 -8.7 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1712 ihfA -1.5 -3.2 integration host factor subunit alpha (NCBI) compare
b2330 yfcB -1.5 -2.9 putative adenine-specific methylase (VIMSS) compare
b0437 clpP -1.5 -6.5 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3628 rfaB -1.5 -10.1 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b4375 prfC -1.5 -6.9 peptide chain release factor 3 (NCBI) compare
b3387 dam -1.5 -9.0 DNA adenine methylase (NCBI) compare
b2363 yfdT -1.5 -2.4 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3794 rffM -1.4 -5.7 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3426 glpD -1.4 -4.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3786 rffE -1.4 -8.5 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3632 rfaQ -1.4 -11.3 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3727 pstC -1.4 -4.6 phosphate transporter subunit (NCBI) compare
b3784 rfe -1.4 -8.4 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b4155 yjeA -1.4 -2.0 putative lysyl-tRNA synthetase (VIMSS) compare
b2617 smpA -1.3 -2.3 small membrane protein A (VIMSS) compare
b3652 recG -1.3 -6.7 ATP-dependent DNA helicase (NCBI) compare
b0088 murD -1.3 -1.4 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b2572 rseA -1.3 -2.8 anti-sigma factor (NCBI) compare
b0015 dnaJ -1.3 -5.7 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b2699 recA -1.3 -1.9 recombinase A (NCBI) compare
b3961 oxyR -1.2 -7.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1861 ruvA -1.2 -2.6 Holliday junction DNA helicase motor protein (NCBI) compare
b1551 b1551 -1.2 -1.7 orf, hypothetical protein (VIMSS) compare
b2215 ompC -1.2 -6.5 outer membrane porin protein C (NCBI) compare
b1278 pgpB -1.2 -2.1 phosphatidylglycerophosphatase B (NCBI) compare
b1333 uspE -1.2 -2.7 stress-induced protein (NCBI) compare
b2281 nuoI -1.2 -2.2 NADH dehydrogenase subunit I (NCBI) compare
b0049 apaH -1.2 -4.9 diadenosinetetraphosphatase (NCBI) compare
b0082 mraW -1.2 -2.6 S-adenosyl-methyltransferase (NCBI) compare
b3781 trxA -1.2 -2.8 thioredoxin 1 (VIMSS) compare
b3150 yraP -1.2 -3.7 hypothetical protein (NCBI) compare
b3912 cpxR -1.2 -6.9 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b2569 lepA -1.1 -4.5 GTP-binding protein LepA (NCBI) compare
b4413 sokC -1.1 -1.6 regulatory antisense RNA (NCBI) compare
b4222 ytfP -1.1 -2.9 hypothetical protein (NCBI) compare
b0065 yabI -1.1 -3.7 conserved inner membrane protein (NCBI) compare
b1075 flgD -1.1 -2.1 flagellar basal body rod modification protein D (NCBI) compare
b0580 ybdJ -1.1 -1.8 predicted inner membrane protein (NCBI) compare
b3911 cpxA -1.1 -7.1 two-component sensor protein (NCBI) compare
b0018 mokC -1.1 -1.2 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b1248 b1248 -1.1 -1.7 orf, hypothetical protein (VIMSS) compare
b2814 metZ -1.1 -1.6 tRNA-Met (NCBI) compare
b0178 hlpA -1.1 -3.7 periplasmic chaperone (NCBI) compare
b3100 yqjK -1.0 -1.6 hypothetical protein (NCBI) compare
b1642 slyA -1.0 -1.1 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1831 proQ -1.0 -3.5 putative solute/DNA competence effector (NCBI) compare
b3871 bipA -1.0 -5.9 GTP-binding protein (NCBI) compare
b3164 pnp -1.0 -2.1 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1709 btuD -1.0 -1.2 vitamin B12-transporter ATPase (NCBI) compare
b3935 priA -1.0 -1.0 primosome assembly protein PriA (NCBI) compare
b3728 pstS -1.0 -4.0 phosphate transporter subunit (NCBI) compare
b0826 moeB -1.0 -3.1 molybdopterin biosynthesis protein MoeB (NCBI) compare
b3785 wzzE -1.0 -6.3 putative transport protein (VIMSS) compare
b0814 ompX -1.0 -3.7 outer membrane protein X (NCBI) compare
b0784 moaD -1.0 -1.7 molybdopterin synthase, small subunit (NCBI) compare
b3183 obgE -1.0 -1.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2897 ygfY -1.0 -1.8 hypothetical protein (NCBI) compare
b1235 rssB -1.0 -4.9 response regulator of RpoS (NCBI) compare
b1669 ydhT -1.0 -1.9 hypothetical protein (NCBI) compare
b1070 flgN -1.0 -1.1 export chaperone for FlgK and FlgL (NCBI) compare
b3404 envZ -1.0 -5.4 osmolarity sensor protein (NCBI) compare
b0471 ybaB -1.0 -2.4 hypothetical protein (NCBI) compare
b2168 fruK -1.0 -1.7 1-phosphofructokinase (NCBI) compare
b3250 mreC -1.0 -1.5 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b0118 acnB -1.0 -3.2 aconitate hydratase (NCBI) compare
b2287 nuoB -1.0 -3.1 NADH dehydrogenase subunit B (NCBI) compare
b0436 tig -1.0 -5.2 trigger factor (NCBI) compare
b0765 modC -1.0 -3.2 molybdate transporter subunit (NCBI) compare
b1777 b1777 -1.0 -2.1 orf, hypothetical protein (VIMSS) compare
b3844 fre -1.0 -4.2 NAD(P)H-flavin reductase (NCBI) compare
b2282 nuoH -1.0 -1.9 NADH dehydrogenase subunit H (NCBI) compare
b1811 yoaH -1.0 -2.3 hypothetical protein (NCBI) compare
b1187 fadR -1.0 -1.9 fatty acid metabolism regulator (NCBI) compare
b3807 cyaY -1.0 -5.2 frataxin-like protein (NCBI) compare
b4201 priB -0.9 -1.1 primosomal replication protein N (NCBI) compare
b0759 galE -0.9 -4.7 UDP-galactose-4-epimerase (VIMSS) compare
b3021 ygiT -0.9 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1304 pspA -0.9 -2.4 regulatory protein for phage-shock-protein operon (NCBI) compare
b3811 xerC -0.9 -2.4 site-specific tyrosine recombinase XerC (NCBI) compare
b0438 clpX -0.9 -4.6 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1370 insH-5 -0.9 -1.1 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3163 nlpI -0.9 -2.4 hypothetical protein (NCBI) compare
b2990 hybG -0.9 -1.4 hydrogenase 2 accessory protein (NCBI) compare
b0862 artQ -0.9 -2.4 arginine transporter subunit (NCBI) compare
b0729 sucD -0.9 -2.2 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1863 ruvC -0.9 -2.4 Holliday junction resolvase (NCBI) compare
b1860 ruvB -0.9 -1.7 Holliday junction DNA helicase B (NCBI) compare
b2278 nuoL -0.9 -5.5 NADH dehydrogenase subunit L (NCBI) compare
b1007 b1007 -0.9 -1.1 orf, hypothetical protein (VIMSS) compare
b0726 sucA -0.9 -2.7 alpha-ketoglutarate decarboxylase (NCBI) compare
b3649 rpoZ -0.8 -2.0 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1540 ydfH -0.8 -1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1758 b1758 -0.8 -1.0 putative cytochrome oxidase (VIMSS) compare
b2113 mrp -0.8 -3.5 putative ATPase (VIMSS) compare
b1257 yciE -0.8 -1.5 hypothetical protein (NCBI) compare
b1550 b1550 -0.8 -1.7 orf, hypothetical protein (VIMSS) compare
b1271 yciK -0.8 -1.9 short chain dehydrogenase (NCBI) compare
b4203 rplI -0.8 -3.4 50S ribosomal protein L9 (NCBI) compare
b1840 yebZ -0.8 -3.2 predicted inner membrane protein (NCBI) compare
b4411 ecnB -0.8 -2.1 entericidin B membrane lipoprotein (NCBI) compare
b3146 yraL -0.8 -3.8 predicted methyltransferase (NCBI) compare
b3892 fdoI -0.8 -3.6 formate dehydrogenase-O, cytochrome b556 subunit (NCBI) compare
b1111 ycfQ -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b1567 intK -0.8 -1.6 Qin prophage; predicted protein (RefSeq) compare
b2266 elaB -0.8 -2.8 hypothetical protein (NCBI) compare
b4472 yhdP -0.8 -6.3 conserved membrane protein, predicted transporter (NCBI) compare
b1305 pspB -0.8 -2.1 phage shock protein B (NCBI) compare


Specific Phenotypes

For 4 genes in this experiment

For stress hexanol in Escherichia coli BW25113

For stress hexanol across organisms