Experiment set4IT072 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

LB_plus_SM_buffer with Br60_phage 0.0000005 MOI

200 most detrimental genes:

  gene name fitness t score description  
GFF3901 +3.0 4.9 Phosphomannomutase (EC 5.4.2.8) compare
GFF828 +2.4 11.0 HflC protein compare
GFF4158 +2.3 7.1 tmRNA-binding protein SmpB compare
GFF3417 +2.3 12.9 FIG002903: a protein of unknown function perhaps involved in purine metabolism compare
GFF827 +2.3 13.5 HflK protein compare
GFF2968 +2.1 11.5 Stringent starvation protein A compare
GFF2967 +1.8 6.8 ClpXP protease specificity-enhancing factor / Stringent starvation protein B compare
GFF3461 +1.5 1.8 hypothetical protein compare
GFF4008 +1.4 4.7 Flagellar biosynthesis protein FliP compare
GFF4015 +1.4 9.1 Flagellum-specific ATP synthase FliI compare
GFF4011 +1.4 10.8 Flagellar motor switch protein FliM compare
GFF4012 +1.3 9.0 Flagellar biosynthesis protein FliL compare
GFF4126 +1.3 1.9 FIG01047407: hypothetical protein compare
GFF4192 +1.3 5.5 DNA-binding protein HU-alpha compare
GFF1143 +1.3 1.7 FIG074102: hypothetical protein compare
GFF3358 +1.3 9.7 Flagellar basal-body rod protein FlgF compare
GFF4839 +1.3 10.4 BarA sensory histidine kinase (= VarS = GacS) compare
GFF3357 +1.3 7.5 Flagellar hook protein FlgE compare
GFF4788 +1.3 7.9 RNA polymerase sigma factor RpoS compare
GFF4016 +1.2 4.0 Flagellar assembly protein FliH compare
GFF4017 +1.1 6.9 Flagellar motor switch protein FliG compare
GFF4006 +1.1 7.9 Flagellar biosynthesis protein FliR compare
GFF3354 +1.1 3.9 Flagellar basal-body rod protein FlgB compare
GFF4013 +1.1 9.0 Flagellar hook-length control protein FliK compare
GFF3146 +1.0 4.8 '3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)' transl_table=11 compare
GFF3360 +1.0 5.1 Flagellar L-ring protein FlgH compare
GFF1661 +1.0 6.8 Flagellar biosynthesis protein FlhB compare
GFF1671 +1.0 8.1 Flagellar motor rotation protein MotA compare
GFF3359 +1.0 4.0 Flagellar basal-body rod protein FlgG compare
GFF4356 +1.0 4.1 DNA-binding protein HU-beta compare
GFF3355 +1.0 3.5 Flagellar basal-body rod protein FlgC compare
GFF3353 +1.0 5.7 Flagellar basal-body P-ring formation protein FlgA compare
GFF826 +1.0 2.5 GTP-binding protein HflX compare
GFF4018 +1.0 4.0 Flagellar M-ring protein FliF compare
GFF1641 +1.0 1.8 hypothetical protein compare
GFF4010 +1.0 3.6 Flagellar motor switch protein FliN compare
GFF4733 +1.0 1.4 Type III secretion transcriptional regulator HilC (= SirC) compare
GFF3905 +1.0 6.6 regulator of length of O-antigen component of lipopolysaccharide chains compare
GFF794 +1.0 1.9 Phage holin compare
GFF1920 +0.9 1.3 hypothetical protein compare
GFF3631 +0.9 3.9 hypothetical protein compare
GFF3362 +0.9 3.5 Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) compare
GFF1699 +0.9 2.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
GFF3395 +0.9 1.5 Putative outer membrane protein compare
GFF3361 +0.9 4.8 Flagellar P-ring protein FlgI compare
GFF4014 +0.9 1.7 Flagellar protein FliJ compare
GFF4007 +0.9 3.2 Flagellar biosynthesis protein FliQ compare
GFF825 +0.9 2.1 RNA-binding protein Hfq compare
GFF3588 +0.8 1.7 Secretion system effector SseB compare
GFF3723 +0.8 1.4 FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) compare
GFF1899 +0.8 3.5 FIG00638298: membrane protein YfbV compare
GFF3356 +0.8 3.6 Flagellar basal-body rod modification protein FlgD compare
GFF1673 +0.8 3.8 Flagellar transcriptional activator FlhD compare
GFF3569 +0.8 2.2 Proline iminopeptidase (EC 3.4.11.5) compare
GFF514 +0.8 3.2 hypothetical protein compare
GFF3515 +0.8 1.3 FIG00637864: hypothetical protein compare
GFF573 +0.8 1.4 FIG01046423: hypothetical protein compare
GFF559 +0.8 1.7 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
GFF4029 +0.8 4.3 Flagellar biosynthesis protein FliC compare
GFF4916 +0.8 2.5 FIG00639119: hypothetical protein compare
GFF1747 +0.8 1.3 putative inner membrane protein compare
GFF1660 +0.8 4.0 Flagellar biosynthesis protein FlhA compare
GFF109 +0.8 1.7 DeoR family transcriptional regulator probably related to glycerate, glycolaldehyde metabolism compare
GFF873 +0.8 1.2 hypothetical protein compare
GFF645 +0.7 1.0 Membrane protein associated with oxaloacetate decarboxylase compare
GFF2825 +0.7 1.7 FIG00638134: hypothetical protein compare
GFF2758 +0.7 1.3 FIG01045187: hypothetical protein compare
GFF32 +0.7 1.1 Rho-specific inhibitor of transcription termination (YaeO) compare
GFF1311 +0.7 5.2 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
GFF2308 +0.7 3.6 Glycerol uptake facilitator protein compare
GFF119 +0.7 0.8 hypothetical protein compare
GFF1690 +0.7 2.6 RNA polymerase sigma factor for flagellar operon compare
GFF3052 +0.7 5.6 Transcriptional regulator, IclR family compare
GFF1670 +0.7 4.9 Flagellar motor rotation protein MotB compare
GFF2906 +0.7 2.8 Protein yifE compare
GFF4810 +0.7 1.1 CRISPR-associated protein, Cse3 family compare
GFF2515 +0.7 1.2 putative outer membrane protein compare
GFF3338 +0.7 1.6 hypothetical protein compare
GFF4118 +0.7 1.6 tRNA-Thr-CGT compare
GFF1109 +0.7 0.8 Putative LysR family transcriptional regulator compare
GFF2501 +0.7 0.9 FIG00638667: hypothetical protein compare
GFF2145 +0.7 0.8 probable ribonuclease inhibitor YPO3690 compare
GFF1383 +0.7 1.9 FIG00639790: hypothetical protein compare
GFF215 +0.7 2.3 FIG01046809: hypothetical protein compare
GFF4020 +0.7 2.3 Flagellar hook-basal body complex protein FliE compare
GFF3545 +0.7 1.3 Transcriptional regulator, AraC family compare
GFF2031 +0.7 1.0 FIG01046611: hypothetical protein compare
GFF3131 +0.7 2.5 TRAP-type C4-dicarboxylate transport system, small permease component compare
GFF2554 +0.7 2.9 Bdm protein compare
GFF3648 +0.7 1.5 tRNA-Arg-TCT compare
GFF4145 +0.6 1.1 hypothetical protein compare
GFF3210 +0.6 2.5 Threonine dehydratase, catabolic (EC 4.3.1.19) compare
GFF2083 +0.6 2.1 Ethanolamine utilization protein EutQ compare
GFF1385 +0.6 0.9 hypothetical protein compare
GFF4350 +0.6 0.8 hypothetical protein compare
GFF520 +0.6 1.6 Universal stress protein A compare
GFF2845 +0.6 3.3 Tail-specific protease precursor (EC 3.4.21.102) compare
GFF1214 +0.6 1.1 Kappa-fimbriae major subunit compare
GFF3350 +0.6 3.5 Flagellar biosynthesis protein FlgN compare
GFF3378 +0.6 0.9 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
GFF4434 +0.6 3.7 Protein fdrA compare
GFF255 +0.6 1.7 hypothetical protein compare
GFF1697 +0.6 2.1 FIG00634007: hypothetical protein compare
GFF1503 +0.6 2.9 Lipoprotein nlpI precursor compare
GFF3331 +0.6 2.3 Acidic protein msyB compare
GFF3449 +0.6 1.8 Putative arylsulfatase regulatory protein compare
GFF3996 +0.6 3.9 DNA-cytosine methyltransferase (EC 2.1.1.37) compare
GFF1685 +0.6 1.4 FIG01045540: hypothetical protein compare
GFF1672 +0.6 2.7 Flagellar transcriptional activator FlhC compare
GFF368 +0.6 1.7 Transcriptional regulator SlmA, TetR family compare
GFF3755 +0.6 0.7 FIG00896318: hypothetical protein compare
GFF773 +0.6 1.2 probable lipoprotein compare
GFF2078 +0.6 1.4 Acetaldehyde dehydrogenase, ethanolamine utilization cluster (EC 1.2.1.10) compare
GFF3363 +0.6 4.8 Flagellar hook-associated protein FlgK compare
GFF1521 +0.6 2.0 rRNA small subunit methyltransferase I compare
GFF1033 +0.6 2.2 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
GFF2160 +0.6 2.4 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF870 +0.6 2.7 FIG00614015: hypothetical protein compare
GFF3364 +0.6 1.2 Flagellar hook-associated protein FlgL compare
GFF4619 +0.6 1.2 hypothetical protein compare
GFF3678 +0.6 1.8 S-adenosylmethionine-dependent methyltransferase Functionally Coupled to the MukBEF Chromosome Partitioning Mechanism compare
GFF3985 +0.6 0.6 Integrase compare
GFF1865 +0.6 1.8 Polymyxin resistance protein PmrD compare
GFF2455 +0.6 3.4 Putative sensory histidine kinase YfhA compare
GFF1307 +0.6 0.9 Prepilin peptidase dependent protein A precursor compare
GFF3305 +0.6 1.9 Sialic acid utilization regulator, RpiR family compare
GFF2388 +0.6 1.6 Large-conductance mechanosensitive channel compare
GFF4615 +0.5 0.9 FIG137478: Hypothetical protein YbgI compare
GFF1239 +0.5 0.9 Gifsy-2 prophage lysozyme( EC:3.2.1.17 ) compare
GFF3295 +0.5 1.2 FIG00895798: hypothetical protein compare
GFF3080 +0.5 2.5 FIG074102: hypothetical protein compare
GFF3961 +0.5 2.3 Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) compare
GFF3346 +0.5 2.3 Ribosomal-protein-S5p-alanine acetyltransferase compare
GFF4883 +0.5 2.3 Mobile element protein compare
GFF3264 +0.5 0.9 hypothetical protein compare
GFF4465 +0.5 1.2 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA compare
GFF3684 +0.5 1.6 Hypothetical metal-binding enzyme, YcbL homolog compare
GFF2002 +0.5 1.3 hypothetical protein compare
GFF795 +0.5 1.6 Phage lysin, 1,4-beta-N-acetylmuramidase (EC 3.2.1.17) or lysozyme compare
GFF609 +0.5 4.1 Ferrous iron transport protein B compare
GFF2257 +0.5 1.3 hypothetical protein compare
GFF1142 +0.5 2.4 Single-stranded DNA-binding protein compare
GFF616 +0.5 1.1 hypothetical protein compare
GFF2720 +0.5 2.3 Hypothetical YciO protein, TsaC/YrdC paralog compare
GFF3321 +0.5 1.0 Minor curlin subunit CsgB, nucleation component of curlin monomers compare
GFF4460 +0.5 1.5 Putative inner membrane protein compare
GFF2445 +0.5 3.3 Stationary phase inducible protein CsiE compare
GFF3341 +0.5 1.2 DNA-damage-inducible protein I compare
GFF540 +0.5 2.4 16S rRNA (guanine(966)-N(2))-methyltransferase (EC 2.1.1.171) compare
GFF460 +0.5 1.3 hypothetical protein compare
GFF4371 +0.5 2.4 methylated-DNA--protein-cysteine methyltransferase-related protein compare
GFF3518 +0.5 0.8 putative outer membrane protein compare
GFF4519 +0.5 1.3 Universal stress protein G compare
GFF2592 +0.5 1.4 secreted effector protein compare
GFF2772 +0.5 2.2 FIG002082: Protein SirB2 compare
GFF1105 +0.5 2.8 Hypothetical fimbrial chaperone ycbF precursor compare
GFF3484 +0.5 1.9 FIG002003: Protein YdjA compare
GFF2167 +0.5 2.7 Polyphosphate kinase (EC 2.7.4.1) compare
GFF4598 +0.5 1.3 Uncharacterized protein ybfE compare
GFF2395 +0.5 0.8 Similar to C-terminal Zn-finger domain of DNA topoisomerase I compare
GFF1817 +0.5 1.7 Cytochrome c-type protein NapC compare
GFF2247 +0.5 1.4 FIG01046414: hypothetical protein compare
GFF4913 +0.5 2.5 FIG00638862: hypothetical protein compare
GFF1022 +0.5 2.1 FIG001826: putative inner membrane protein compare
GFF518 +0.5 0.8 rRNA small subunit methyltransferase J compare
GFF4036 +0.5 1.3 tRNA-Ser-CGA compare
GFF3426 +0.5 1.3 Virulence protein MsgA compare
GFF2049 +0.5 0.7 FIG01045978: hypothetical protein compare
GFF85 +0.5 2.7 '2'-5' RNA ligase' transl_table=11 compare
GFF2678 +0.5 1.5 Thiol peroxidase, Tpx-type (EC 1.11.1.15) compare
GFF2418 +0.5 1.3 Anaerobic dimethyl sulfoxide reductase chain B (EC 1.8.5.3) compare
GFF2858 +0.5 1.0 G-nucleotide exchange factor SopE compare
GFF675 +0.5 3.4 Excinuclease ABC subunit B compare
GFF1863 +0.5 0.8 Polymyxin resistance protein PmrL, sucrose-6 phosphate hydrolase compare
GFF2001 +0.5 0.7 Quaternary ammonium compound-resistance protein SugE compare
GFF4111 +0.5 0.7 Curlin genes transcriptional activator compare
GFF1415 +0.5 0.5 UPF0337 protein yjbJ compare
GFF3088 +0.5 2.4 Putative cytoplasmic protein USSDB7A compare
GFF2828 +0.5 2.2 L-serine dehydratase, beta subunit (EC 4.3.1.17) / L-serine dehydratase, alpha subunit (EC 4.3.1.17) compare
GFF3347 +0.5 2.5 Protein of unknown function YceH compare
GFF1231 +0.5 1.6 Invasin compare
GFF2269 +0.5 1.1 hypothetical protein compare
GFF4401 +0.4 2.2 Cys-tRNA(Pro) deacylase YbaK compare
GFF3393 +0.4 2.5 FIG01200701: possible membrane protein compare
GFF3390 +0.4 2.5 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
GFF4139 +0.4 1.6 PTS system, glucitol/sorbitol-specific IIC component (EC 2.7.1.69) compare
GFF2895 +0.4 0.7 Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) compare
GFF4791 +0.4 2.3 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
GFF4808 +0.4 1.9 CRISPR-associated protein, Cas2 compare
GFF1543 +0.4 1.5 DNA-invertase compare
GFF2019 +0.4 1.3 FIG01049542: hypothetical protein compare
GFF1088 +0.4 0.4 FIG01045785: hypothetical protein compare
GFF2085 +0.4 1.0 Ethanolamine utilization polyhedral-body-like protein EutS compare
GFF2307 +0.4 3.5 Glycerol kinase (EC 2.7.1.30) compare
GFF2141 +0.4 2.2 LysR family transcriptional regulator QseA compare
GFF743 +0.4 2.3 Uncharacterized glutathione S-transferase-like protein compare
GFF4644 +0.4 1.0 hypothetical protein compare
GFF2907 +0.4 3.1 HTH-type transcriptional regulator hdfR compare
GFF2963 +0.4 2.3 N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9) compare
GFF1933 +0.4 2.0 DedA protein compare


Specific Phenotypes

For 1 genes in this experiment

For phage Br60_phage in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

For phage Br60_phage across organisms