Experiment set4IT063 for Escherichia coli BW25113

Compare to:

LB with octane 5 vol%

200 most important genes:

  gene name fitness t score description  
b0463 acrA -7.1 -8.4 multidrug efflux system (NCBI) compare
b0462 acrB -6.8 -14.5 multidrug efflux system protein (NCBI) compare
b3035 tolC -5.1 -12.8 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0222 lpcA -5.0 -3.5 phosphoheptose isomerase (NCBI) compare
b3052 rfaE -4.6 -6.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3621 rfaC -4.5 -3.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3619 rfaD -4.3 -4.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3620 rfaF -3.8 -5.2 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0630 lipB -3.7 -3.6 protein of lipoate biosynthesis (VIMSS) compare
b0118 acnB -3.6 -5.5 aconitate hydratase (NCBI) compare
b0200 gmhB -3.4 -2.3 hypothetical protein (NCBI) compare
b2699 recA -3.1 -4.1 recombinase A (NCBI) compare
b2330 yfcB -2.9 -4.3 putative adenine-specific methylase (VIMSS) compare
b4375 prfC -2.7 -10.6 peptide chain release factor 3 (NCBI) compare
b2567 rnc -2.7 -3.1 ribonuclease III (NCBI) compare
b4177 purA -2.6 -5.2 adenylosuccinate synthetase (NCBI) compare
b4172 hfq -2.6 -3.5 RNA-binding protein Hfq (NCBI) compare
b0726 sucA -2.5 -5.7 alpha-ketoglutarate decarboxylase (NCBI) compare
b3792 wzxE -2.4 -10.9 O-antigen translocase (NCBI) compare
b4155 yjeA -2.4 -2.8 putative lysyl-tRNA synthetase (VIMSS) compare
b2935 tktA -2.3 -5.0 transketolase 1, thiamin-binding (NCBI) compare
b3725 pstB -2.2 -4.2 phosphate transporter subunit (NCBI) compare
b0738 tolR -2.2 -5.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3162 deaD -2.2 -8.1 inducible ATP-independent RNA helicase (VIMSS) compare
b2285 nuoE -2.2 -4.0 NADH dehydrogenase subunit E (NCBI) compare
b0737 tolQ -2.1 -4.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2279 nuoK -2.0 -2.5 NADH dehydrogenase subunit K (NCBI) compare
b3462 ftsX -2.0 -7.6 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2282 nuoH -1.9 -4.3 NADH dehydrogenase subunit H (NCBI) compare
b3386 rpe -1.9 -2.5 ribulose-phosphate 3-epimerase (NCBI) compare
b0739 tolA -1.9 -5.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1236 galU -1.8 -7.3 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0722 sdhD -1.8 -5.8 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1292 sapC -1.8 -3.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3183 obgE -1.8 -2.4 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2820 recB -1.8 -4.1 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0683 fur -1.7 -1.8 ferric uptake regulator (NCBI) compare
b0114 aceE -1.7 -3.5 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3426 glpD -1.6 -6.6 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3500 gor -1.6 -1.8 glutathione reductase (NCBI) compare
b2620 smpB -1.5 -3.0 SsrA-binding protein (NCBI) compare
b1290 sapF -1.5 -2.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0890 ftsK -1.5 -8.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3728 pstS -1.5 -6.1 phosphate transporter subunit (NCBI) compare
b3609 secB -1.5 -2.9 export protein SecB (NCBI) compare
b2276 nuoN -1.4 -5.4 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0740 tolB -1.4 -6.2 translocation protein TolB precursor (NCBI) compare
b3463 ftsE -1.4 -4.7 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0949 uup -1.3 -7.4 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3390 aroK -1.3 -2.9 shikimate kinase I (NCBI) compare
b3811 xerC -1.3 -3.5 site-specific tyrosine recombinase XerC (NCBI) compare
b0263 afuB -1.3 -2.9 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b4613 dinQ -1.3 -2.2 Damage inducible, function unknown (RefSeq) compare
b4685 yrbN -1.3 -2.8 expressed protein (RefSeq) compare
b3631 rfaG -1.2 -10.2 glucosyltransferase I (NCBI) compare
b2277 nuoM -1.2 -6.3 NADH dehydrogenase subunit M (NCBI) compare
b3630 rfaP -1.2 -8.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3871 bipA -1.2 -7.9 GTP-binding protein (NCBI) compare
b3741 gidA -1.2 -7.1 glucose-inhibited division protein A (NCBI) compare
b2278 nuoL -1.2 -8.1 NADH dehydrogenase subunit L (NCBI) compare
b0051 ksgA -1.2 -4.5 dimethyladenosine transferase (NCBI) compare
b4557 yidD -1.2 -2.7 hypothetical protein (NCBI) compare
b2822 recC -1.2 -3.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4042 dgkA -1.2 -3.4 diacylglycerol kinase (NCBI) compare
b2287 nuoB -1.2 -3.4 NADH dehydrogenase subunit B (NCBI) compare
b2280 nuoJ -1.2 -4.3 NADH dehydrogenase subunit J (NCBI) compare
b2187 yejL -1.2 -3.2 hypothetical protein (NCBI) compare
b0049 apaH -1.2 -5.7 diadenosinetetraphosphatase (NCBI) compare
b3198 kdsC -1.2 -2.5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b4239 treC -1.2 -4.7 trehalose-6-P hydrolase (NCBI) compare
b3781 trxA -1.2 -2.6 thioredoxin 1 (VIMSS) compare
b0721 sdhC -1.2 -4.8 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b3806 cyaA -1.1 -4.4 adenylate cyclase (NCBI) compare
b2258 b2258 -1.1 -1.9 putative transport/receptor protein (VIMSS) compare
b3844 fre -1.1 -4.8 NAD(P)H-flavin reductase (NCBI) compare
b3398 yrfF -1.1 -2.9 predicted inner membrane protein (NCBI) compare
b2284 nuoF -1.1 -4.4 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0439 lon -1.1 -5.1 DNA-binding ATP-dependent protease La (NCBI) compare
b3290 trkA -1.1 -3.7 potassium transporter peripheral membrane component (NCBI) compare
b2283 nuoG -1.1 -6.1 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2297 pta -1.1 -1.9 phosphate acetyltransferase (NCBI) compare
b3842 rfaH -1.1 -4.0 transcriptional activator RfaH (NCBI) compare
b2209 eco -1.1 -3.0 ecotin precursor (NCBI) compare
b2313 cvpA -1.1 -4.5 membrane protein required for colicin V production (NCBI) compare
b1084 rne -1.1 -4.9 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b0053 surA -1.0 -5.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2576 srmB -1.0 -3.5 ATP-dependent RNA helicase (NCBI) compare
b0724 sdhB -1.0 -4.7 succinate dehydrogenase, FeS subunit (NCBI) compare
b3199 yrbK -1.0 -0.9 hypothetical protein (NCBI) compare
b3613 yibP -1.0 -4.4 putative membrane protein (VIMSS) compare
b0145 dksA -1.0 -2.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2288 nuoA -1.0 -3.2 NADH dehydrogenase I chain A (VIMSS) compare
b0741 pal -1.0 -3.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1388 paaA -1.0 -2.8 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b3204 ptsN -1.0 -4.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b3727 pstC -1.0 -3.6 phosphate transporter subunit (NCBI) compare
b1167 ymgC -0.9 -2.6 hypothetical protein (NCBI) compare
b3706 trmE -0.9 -4.7 tRNA modification GTPase (NCBI) compare
b0728 sucC -0.9 -4.3 succinyl-CoA synthetase subunit beta (NCBI) compare
b2363 yfdT -0.9 -2.5 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b1524 yneH -0.9 -1.7 predicted glutaminase (NCBI) compare
b0888 trxB -0.9 -3.3 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3979 thrT -0.9 -1.1 tRNA-Thr (NCBI) compare
b3726 pstA -0.9 -4.2 phosphate transporter subunit (NCBI) compare
b3778 rep -0.9 -5.8 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b0560 nohB -0.9 -2.2 DLP12 prophage; DNA packaging protein (NCBI) compare
b3164 pnp -0.9 -2.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2281 nuoI -0.9 -2.7 NADH dehydrogenase subunit I (NCBI) compare
b0723 sdhA -0.9 -5.4 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b3026 qseC -0.9 -4.0 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4139 aspA -0.8 -5.8 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2947 gshB -0.8 -3.5 glutathione synthetase (NCBI) compare
b0720 gltA -0.8 -4.1 citrate synthase (NCBI) compare
b1111 ycfQ -0.8 -2.9 orf, hypothetical protein (VIMSS) compare
b0232 yafN -0.8 -1.1 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b2897 ygfY -0.8 -1.5 hypothetical protein (NCBI) compare
b3616 tdh -0.8 -3.9 L-threonine 3-dehydrogenase (NCBI) compare
b2340 sixA -0.8 -3.4 phosphohistidine phosphatase (NCBI) compare
b3414 gntY -0.8 -4.1 predicted gluconate transport associated protein (NCBI) compare
b2569 lepA -0.8 -3.6 GTP-binding protein LepA (NCBI) compare
b2479 gcvR -0.8 -2.8 transcriptional regulation of gcv operon (VIMSS) compare
b3636 rpmG -0.8 -1.7 50S ribosomal protein L33 (NCBI) compare
b3617 kbl -0.8 -4.5 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b0431 cyoB -0.8 -5.3 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b0428 cyoE -0.8 -3.5 protoheme IX farnesyltransferase (NCBI) compare
b1861 ruvA -0.8 -2.2 Holliday junction DNA helicase motor protein (NCBI) compare
b4234 yjgA -0.8 -3.1 hypothetical protein (NCBI) compare
b0429 cyoD -0.8 -3.1 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0471 ybaB -0.8 -2.7 hypothetical protein (NCBI) compare
b0585 fes -0.8 -3.4 enterobactin/ferric enterobactin esterase (NCBI) compare
b1530 marR -0.7 -3.3 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b1765 ydjA -0.7 -1.3 predicted oxidoreductase (NCBI) compare
b1658 purR -0.7 -3.4 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3465 yhhF -0.7 -3.8 predicted methyltransferase (NCBI) compare
b2531 iscR -0.7 -1.7 DNA-binding transcriptional repressor (NCBI) compare
b2286 nuoC -0.7 -3.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0688 pgm -0.7 -2.6 phosphoglucomutase (NCBI) compare
b0729 sucD -0.7 -2.1 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0928 aspC -0.7 -3.5 aspartate aminotransferase, PLP-dependent (NCBI) compare
b0438 clpX -0.7 -4.6 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1205 ychH -0.7 -1.8 predicted inner membrane protein (NCBI) compare
b3341 rpsG -0.7 -1.1 30S ribosomal protein S7 (NCBI) compare
b0432 cyoA -0.7 -5.0 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3870 glnA -0.7 -2.2 glutamine synthetase (NCBI) compare
b0113 pdhR -0.7 -2.6 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b3236 mdh -0.7 -4.0 malate dehydrogenase (NCBI) compare
b2248 yfaX -0.7 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b3082 ygjM -0.7 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1992 cobS -0.7 -2.2 cobalamin synthase (NCBI) compare
b4163 glyV -0.7 -1.5 tRNA-Gly (NCBI) compare
b3807 cyaY -0.7 -3.4 frataxin-like protein (NCBI) compare
b3649 rpoZ -0.7 -2.1 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3229 sspA -0.6 -2.5 stringent starvation protein A (NCBI) compare
b3849 trkH -0.6 -4.8 potassium transporter (NCBI) compare
b1575 dicB -0.6 -1.8 Qin prophage; cell division inhibition protein (NCBI) compare
b2564 pdxJ -0.6 -2.6 pyridoxal phosphate biosynthetic protein (NCBI) compare
b1676 pykF -0.6 -3.1 pyruvate kinase (NCBI) compare
b3493 pitA -0.6 -3.9 phosphate transporter, low-affinity (NCBI) compare
b2061 wzb -0.6 -1.7 protein-tyrosine phosphatase (NCBI) compare
b1370 insH-5 -0.6 -0.9 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b2318 truA -0.6 -2.8 tRNA pseudouridine synthase A (NCBI) compare
b3289 rsmB -0.6 -4.7 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) compare
b2528 iscA -0.6 -1.3 iron-sulfur cluster assembly protein (NCBI) compare
b1478 adhP -0.6 -2.3 alcohol dehydrogenase (VIMSS) compare
b2912 ygfA -0.6 -2.5 putative ligase (VIMSS) compare
b2894 xerD -0.6 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b3858 yihD -0.6 -1.7 hypothetical protein (NCBI) compare
b3839 tatC -0.6 -3.4 TatABCE protein translocation system subunit (NCBI) compare
b2017 yefM -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b2937 speB -0.6 -3.5 agmatinase (NCBI) compare
b0082 mraW -0.6 -2.2 S-adenosyl-methyltransferase (NCBI) compare
b4460 araH -0.6 -2.2 fused L-arabinose transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b2136 yohD -0.6 -1.3 orf, hypothetical protein (VIMSS) compare
b0340 cynS -0.6 -1.4 cyanate hydratase (NCBI) compare
b1977 asnT -0.6 -1.9 tRNA-Asn (NCBI) compare
b2518 ndk -0.6 -1.8 nucleoside diphosphate kinase (NCBI) compare
b3962 udhA -0.6 -4.0 putative oxidoreductase (VIMSS) compare
b3632 rfaQ -0.6 -5.1 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1628 rsxB -0.6 -2.0 electron transport complex protein RnfB (NCBI) compare
b3790 rffC -0.6 -2.9 TDP-fucosamine acetyltransferase (RefSeq) compare
b2948 yqgE -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b0746 valZ -0.6 -0.7 tRNA-Val (NCBI) compare
b4179 vacB -0.6 -3.1 putative enzyme (VIMSS) compare
b1293 sapB -0.5 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0564 appY -0.5 -1.1 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1187 fadR -0.5 -2.6 fatty acid metabolism regulator (NCBI) compare
b1179 ycgL -0.5 -1.7 conserved protein (NCBI) compare
b2501 ppk -0.5 -4.0 polyphosphate kinase (NCBI) compare
b3190 yrbA -0.5 -2.2 orf, hypothetical protein (VIMSS) compare
b2141 yohJ -0.5 -1.6 hypothetical protein (NCBI) compare
b3232 yhcM -0.5 -3.4 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b2325 yfcL -0.5 -2.1 hypothetical protein (NCBI) compare
b3237 argR -0.5 -2.5 arginine repressor (NCBI) compare
b2012 yeeD -0.5 -1.5 hypothetical protein (NCBI) compare
b4180 rlmB -0.5 -3.0 23S rRNA (Gm2251)-methyltransferase (NCBI) compare
b3688 yidQ -0.5 -2.9 orf, hypothetical protein (VIMSS) compare
b0080 fruR -0.5 -2.5 DNA-binding transcriptional dual regulator (NCBI) compare
b2688 gshA -0.5 -3.3 glutamate--cysteine ligase (NCBI) compare
b4222 ytfP -0.5 -2.4 hypothetical protein (NCBI) compare
b1868 yecE -0.5 -1.9 hypothetical protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress octane across organisms