Experiment set4IT060 for Escherichia coli BW25113

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
b3341 rpsG -3.5 -2.6 30S ribosomal protein S7 (NCBI) compare
b2330 yfcB -3.5 -4.1 putative adenine-specific methylase (VIMSS) compare
b3725 pstB -2.9 -4.7 phosphate transporter subunit (NCBI) compare
b0118 acnB -2.7 -5.8 aconitate hydratase (NCBI) compare
b3390 aroK -2.7 -3.8 shikimate kinase I (NCBI) compare
b2820 recB -2.7 -4.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4375 prfC -2.5 -10.3 peptide chain release factor 3 (NCBI) compare
b2699 recA -2.5 -3.7 recombinase A (NCBI) compare
b0630 lipB -2.4 -3.4 protein of lipoate biosynthesis (VIMSS) compare
b2894 xerD -2.3 -2.6 site-specific tyrosine recombinase XerD (NCBI) compare
b0726 sucA -2.2 -4.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b2567 rnc -2.2 -2.9 ribonuclease III (NCBI) compare
b4177 purA -2.1 -5.0 adenylosuccinate synthetase (NCBI) compare
b3162 deaD -2.1 -7.9 inducible ATP-independent RNA helicase (VIMSS) compare
b3792 wzxE -2.1 -9.7 O-antigen translocase (NCBI) compare
b3183 obgE -2.1 -2.7 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4163 glyV -2.0 -3.0 tRNA-Gly (NCBI) compare
b4685 yrbN -1.9 -3.8 expressed protein (RefSeq) compare
b0200 gmhB -1.8 -2.7 hypothetical protein (NCBI) compare
b2620 smpB -1.8 -3.1 SsrA-binding protein (NCBI) compare
b1860 ruvB -1.8 -2.2 Holliday junction DNA helicase B (NCBI) compare
b2576 srmB -1.7 -5.2 ATP-dependent RNA helicase (NCBI) compare
b4155 yjeA -1.7 -2.5 putative lysyl-tRNA synthetase (VIMSS) compare
b2279 nuoK -1.7 -2.3 NADH dehydrogenase subunit K (NCBI) compare
b2822 recC -1.6 -5.2 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0888 trxB -1.6 -4.7 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0949 uup -1.5 -8.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0890 ftsK -1.4 -8.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2569 lepA -1.4 -4.9 GTP-binding protein LepA (NCBI) compare
b1279 yciS -1.4 -1.7 conserved inner membrane protein (NCBI) compare
b3778 rep -1.4 -8.6 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3728 pstS -1.3 -5.2 phosphate transporter subunit (NCBI) compare
b3290 trkA -1.3 -4.2 potassium transporter peripheral membrane component (NCBI) compare
b4201 priB -1.3 -2.8 primosomal replication protein N (NCBI) compare
b3871 bipA -1.2 -8.5 GTP-binding protein (NCBI) compare
b0683 fur -1.2 -2.5 ferric uptake regulator (NCBI) compare
b2277 nuoM -1.2 -6.3 NADH dehydrogenase subunit M (NCBI) compare
b0737 tolQ -1.2 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1286 rnb -1.2 -3.5 exoribonuclease II (NCBI) compare
b0439 lon -1.2 -5.3 DNA-binding ATP-dependent protease La (NCBI) compare
b3619 rfaD -1.2 -4.1 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2286 nuoC -1.1 -4.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0722 sdhD -1.1 -3.6 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b2284 nuoF -1.1 -5.0 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b4146 yjeK -1.1 -3.8 predicted lysine aminomutase (NCBI) compare
b2281 nuoI -1.1 -2.6 NADH dehydrogenase subunit I (NCBI) compare
b3741 gidA -1.1 -6.5 glucose-inhibited division protein A (NCBI) compare
b3398 yrfF -1.1 -3.5 predicted inner membrane protein (NCBI) compare
b0721 sdhC -1.1 -4.0 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2518 ndk -1.1 -2.9 nucleoside diphosphate kinase (NCBI) compare
b3204 ptsN -1.0 -4.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b1290 sapF -1.0 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3706 trmE -1.0 -5.0 tRNA modification GTPase (NCBI) compare
b3052 rfaE -1.0 -4.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3169 nusA -1.0 -3.0 transcription elongation factor NusA (NCBI) compare
b2287 nuoB -1.0 -2.9 NADH dehydrogenase subunit B (NCBI) compare
b3621 rfaC -1.0 -4.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1292 sapC -1.0 -2.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2935 tktA -1.0 -3.1 transketolase 1, thiamin-binding (NCBI) compare
b2363 yfdT -1.0 -3.5 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b0723 sdhA -1.0 -6.2 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b2953 yggU -1.0 -1.2 orf, hypothetical protein (VIMSS) compare
b2280 nuoJ -1.0 -3.8 NADH dehydrogenase subunit J (NCBI) compare
b4139 aspA -1.0 -6.5 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2278 nuoL -1.0 -6.7 NADH dehydrogenase subunit L (NCBI) compare
b3462 ftsX -0.9 -4.6 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3616 tdh -0.9 -4.1 L-threonine 3-dehydrogenase (NCBI) compare
b2479 gcvR -0.9 -4.0 transcriptional regulation of gcv operon (VIMSS) compare
b3806 cyaA -0.9 -4.2 adenylate cyclase (NCBI) compare
b3237 argR -0.9 -4.2 arginine repressor (NCBI) compare
b2283 nuoG -0.9 -5.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3426 glpD -0.9 -4.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0232 yafN -0.9 -1.3 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3811 xerC -0.9 -2.4 site-specific tyrosine recombinase XerC (NCBI) compare
b1434 ydcN -0.9 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0051 ksgA -0.9 -3.6 dimethyladenosine transferase (NCBI) compare
b0724 sdhB -0.8 -4.1 succinate dehydrogenase, FeS subunit (NCBI) compare
b4239 treC -0.8 -3.9 trehalose-6-P hydrolase (NCBI) compare
b1370 insH-5 -0.8 -2.2 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b4255 yjgD -0.8 -3.5 hypothetical protein (NCBI) compare
b1861 ruvA -0.8 -1.7 Holliday junction DNA helicase motor protein (NCBI) compare
b2285 nuoE -0.8 -2.2 NADH dehydrogenase subunit E (NCBI) compare
b4453 ldrD -0.8 -2.1 toxic polypeptide, small (NCBI) compare
b3630 rfaP -0.8 -6.0 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3609 secB -0.8 -2.7 export protein SecB (NCBI) compare
b1904 yecR -0.8 -3.0 hypothetical protein (NCBI) compare
b2897 ygfY -0.8 -1.8 hypothetical protein (NCBI) compare
b0729 sucD -0.8 -2.6 succinyl-CoA synthetase subunit alpha (NCBI) compare
b4234 yjgA -0.8 -2.8 hypothetical protein (NCBI) compare
b4418 sraB -0.8 -1.4 unknown RNA (NCBI) compare
b3870 glnA -0.8 -2.5 glutamine synthetase (NCBI) compare
b4179 vacB -0.8 -4.6 putative enzyme (VIMSS) compare
b2288 nuoA -0.8 -2.5 NADH dehydrogenase I chain A (VIMSS) compare
b3727 pstC -0.8 -3.9 phosphate transporter subunit (NCBI) compare
b2948 yqgE -0.8 -1.8 orf, hypothetical protein (VIMSS) compare
b3620 rfaF -0.7 -3.3 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3386 rpe -0.7 -1.5 ribulose-phosphate 3-epimerase (NCBI) compare
b1192 ldcA -0.7 -3.6 L,D-carboxypeptidase A (NCBI) compare
b1863 ruvC -0.7 -2.4 Holliday junction resolvase (NCBI) compare
b2258 b2258 -0.7 -1.4 putative transport/receptor protein (VIMSS) compare
b1551 b1551 -0.7 -2.3 orf, hypothetical protein (VIMSS) compare
b0928 aspC -0.7 -3.7 aspartate aminotransferase, PLP-dependent (NCBI) compare
b1062 pyrC -0.7 -4.6 dihydroorotase (NCBI) compare
b3617 kbl -0.7 -4.0 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b0049 apaH -0.7 -3.2 diadenosinetetraphosphatase (NCBI) compare
b3781 trxA -0.7 -2.6 thioredoxin 1 (VIMSS) compare
b1299 puuR -0.7 -2.9 DNA-binding transcriptional repressor (NCBI) compare
b2276 nuoN -0.7 -3.2 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3463 ftsE -0.7 -2.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1205 ychH -0.7 -1.6 predicted inner membrane protein (NCBI) compare
b0739 tolA -0.7 -2.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1658 purR -0.7 -3.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2297 pta -0.7 -1.3 phosphate acetyltransferase (NCBI) compare
b0767 ybhE -0.7 -2.8 6-phosphogluconolactonase (NCBI) compare
b0431 cyoB -0.6 -4.8 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3198 kdsC -0.6 -2.2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3026 qseC -0.6 -2.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3493 pitA -0.6 -4.6 phosphate transporter, low-affinity (NCBI) compare
b0866 ybjQ -0.6 -1.0 hypothetical protein (NCBI) compare
b0428 cyoE -0.6 -3.2 protoheme IX farnesyltransferase (NCBI) compare
b3631 rfaG -0.6 -5.4 glucosyltransferase I (NCBI) compare
b2830 nudH -0.6 -1.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b1291 sapD -0.6 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4413 sokC -0.6 -1.4 regulatory antisense RNA (NCBI) compare
b0740 tolB -0.6 -3.2 translocation protein TolB precursor (NCBI) compare
b2319 usg -0.6 -2.7 hypothetical protein (NCBI) compare
b1185 dsbB -0.6 -2.0 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b3849 trkH -0.6 -4.5 potassium transporter (NCBI) compare
b3726 pstA -0.6 -2.4 phosphate transporter subunit (NCBI) compare
b2993 hybD -0.6 -2.5 predicted maturation element for hydrogenase 2 (NCBI) compare
b0114 aceE -0.6 -1.5 pyruvate dehydrogenase subunit E1 (NCBI) compare
b2318 truA -0.6 -2.0 tRNA pseudouridine synthase A (NCBI) compare
b2809 b2809 -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b3035 tolC -0.6 -3.5 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2814 metZ -0.6 -1.2 tRNA-Met (NCBI) compare
b2325 yfcL -0.6 -2.3 hypothetical protein (NCBI) compare
b3844 fre -0.6 -3.0 NAD(P)H-flavin reductase (NCBI) compare
b1777 b1777 -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b1357 ydaS -0.6 -1.8 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b1332 ynaJ -0.5 -1.1 predicted inner membrane protein (NCBI) compare
b2506 yfgI -0.5 -1.0 hypothetical protein (NCBI) compare
b3002 yqhA -0.5 -1.4 hypothetical protein (NCBI) compare
b3236 mdh -0.5 -3.5 malate dehydrogenase (NCBI) compare
b1438 ydcQ -0.5 -1.8 predicted DNA-binding transcriptional regulator (RefSeq) compare
b2340 sixA -0.5 -2.2 phosphohistidine phosphatase (NCBI) compare
b2937 speB -0.5 -3.1 agmatinase (NCBI) compare
b1095 fabF -0.5 -3.6 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b4589 ylcI -0.5 -1.5 hypothetical protein (RefSeq) compare
b0149 mrcB -0.5 -4.3 penicillin-binding protein 1b (NCBI) compare
b0082 mraW -0.5 -2.2 S-adenosyl-methyltransferase (NCBI) compare
b0738 tolR -0.5 -1.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3119 tdcR -0.5 -1.8 threonine dehydratase operon activator protein (VIMSS) compare
b1989 asnV -0.5 -1.7 tRNA-Asn (NCBI) compare
b0222 lpcA -0.5 -1.7 phosphoheptose isomerase (NCBI) compare
b1236 galU -0.5 -2.8 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1850 eda -0.5 -1.5 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1125 potB -0.5 -1.6 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4172 hfq -0.5 -1.1 RNA-binding protein Hfq (NCBI) compare
b0438 clpX -0.5 -3.4 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0432 cyoA -0.5 -3.3 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b1253 yciA -0.5 -1.5 predicted hydrolase (NCBI) compare
b1499 ydeO -0.5 -1.8 predicted DNA-binding transcriptional acfivator (NCBI) compare
b4063 soxR -0.5 -2.3 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing (NCBI) compare
b3414 gntY -0.5 -2.8 predicted gluconate transport associated protein (NCBI) compare
b0018 mokC -0.5 -0.9 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b4208 cycA -0.5 -3.5 D-alanine/D-serine/glycine transporter (NCBI) compare
b3232 yhcM -0.5 -3.1 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b3962 udhA -0.5 -3.6 putative oxidoreductase (VIMSS) compare
b2393 nupC -0.5 -3.0 nucleoside (except guanosine) transporter (NCBI) compare
b1390 paaC -0.5 -1.3 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b0617 citD -0.5 -1.4 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b2892 recJ -0.5 -3.3 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b1103 ycfF -0.5 -1.1 orf, hypothetical protein (VIMSS) compare
b3229 sspA -0.5 -1.7 stringent starvation protein A (NCBI) compare
b2282 nuoH -0.5 -1.4 NADH dehydrogenase subunit H (NCBI) compare
b1728 ydjM -0.5 -1.2 predicted inner membrane protein regulated by LexA (RefSeq) compare
b4631 ykgQ -0.5 -1.0 no description compare
b3500 gor -0.5 -1.0 glutathione reductase (NCBI) compare
b1685 ydiH -0.5 -0.9 predicted protein (RefSeq) compare
b0605 ahpC -0.5 -1.9 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b0881 clpS -0.5 -1.5 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b0948 ycbY -0.5 -3.4 predicted methyltransferase (NCBI) compare
b2187 yejL -0.5 -1.6 hypothetical protein (NCBI) compare
b2055 wcaE -0.5 -1.5 predicted glycosyl transferase (NCBI) compare
b0389 yaiA -0.5 -1.7 hypothetical protein (NCBI) compare
b1235 rssB -0.5 -3.2 response regulator of RpoS (NCBI) compare
b1412 azoR -0.5 -1.4 acyl carrier protein phosphodiesterase (NCBI) compare
b2456 cchB -0.5 -1.1 predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) compare
b3545 proK -0.5 -1.5 tRNA-Pro (NCBI) compare
b3289 rsmB -0.5 -3.6 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) compare
b1217 chaB -0.5 -1.0 cation transport regulator (NCBI) compare
b3649 rpoZ -0.5 -1.4 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1882 cheY -0.4 -1.0 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b2424 cysU -0.4 -0.9 sulfate/thiosulfate transporter subunit (NCBI) compare
b1120 cobB -0.4 -1.9 deacetylase of acs and cheY, regulates chemotaxis (NCBI) compare
b3082 ygjM -0.4 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1977 asnT -0.4 -1.2 tRNA-Asn (NCBI) compare
b2846 yqeH -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b2717 hycI -0.4 -2.7 protease involved in processing C-terminal end of HycE (NCBI) compare
b4076 nrfG -0.4 -2.2 heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfG (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments