Experiment set4IT059 for Escherichia coli BW25113

Compare to:

LB

200 most important genes:

  gene name fitness t score description  
b3863 polA -3.8 -2.6 DNA polymerase I (NCBI) compare
b2330 yfcB -3.7 -4.3 putative adenine-specific methylase (VIMSS) compare
b2699 recA -2.9 -3.9 recombinase A (NCBI) compare
b0630 lipB -2.9 -3.9 protein of lipoate biosynthesis (VIMSS) compare
b3725 pstB -2.8 -4.7 phosphate transporter subunit (NCBI) compare
b3183 obgE -2.6 -2.9 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4375 prfC -2.5 -10.5 peptide chain release factor 3 (NCBI) compare
b0118 acnB -2.5 -5.8 aconitate hydratase (NCBI) compare
b2820 recB -2.4 -5.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2894 xerD -2.3 -3.1 site-specific tyrosine recombinase XerD (NCBI) compare
b3290 trkA -2.1 -5.6 potassium transporter peripheral membrane component (NCBI) compare
b2285 nuoE -2.1 -4.0 NADH dehydrogenase subunit E (NCBI) compare
b3162 deaD -2.0 -6.9 inducible ATP-independent RNA helicase (VIMSS) compare
b0888 trxB -1.9 -4.0 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b2569 lepA -1.8 -6.5 GTP-binding protein LepA (NCBI) compare
b4177 purA -1.8 -4.6 adenylosuccinate synthetase (NCBI) compare
b0200 gmhB -1.7 -2.7 hypothetical protein (NCBI) compare
b2576 srmB -1.6 -4.9 ATP-dependent RNA helicase (NCBI) compare
b4699 fnrS -1.6 -1.9 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b2528 iscA -1.6 -2.2 iron-sulfur cluster assembly protein (NCBI) compare
b0726 sucA -1.6 -4.4 alpha-ketoglutarate decarboxylase (NCBI) compare
b2279 nuoK -1.5 -2.5 NADH dehydrogenase subunit K (NCBI) compare
b4585 sroB -1.5 -1.8 Novel sRNA, function unknown (RefSeq) compare
b3636 rpmG -1.5 -2.2 50S ribosomal protein L33 (NCBI) compare
b2935 tktA -1.4 -4.0 transketolase 1, thiamin-binding (NCBI) compare
b2281 nuoI -1.4 -3.2 NADH dehydrogenase subunit I (NCBI) compare
b2822 recC -1.3 -4.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1292 sapC -1.3 -3.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0738 tolR -1.3 -4.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0949 uup -1.3 -7.9 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4155 yjeA -1.3 -1.9 putative lysyl-tRNA synthetase (VIMSS) compare
b3390 aroK -1.2 -2.8 shikimate kinase I (NCBI) compare
b3463 ftsE -1.2 -5.0 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1293 sapB -1.2 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3728 pstS -1.2 -4.4 phosphate transporter subunit (NCBI) compare
b0737 tolQ -1.2 -3.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3977 tyrU -1.2 -1.5 tRNA-Tyr (NCBI) compare
b1290 sapF -1.1 -2.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2620 smpB -1.1 -2.0 SsrA-binding protein (NCBI) compare
b3741 gidA -1.1 -6.9 glucose-inhibited division protein A (NCBI) compare
b2276 nuoN -1.1 -3.7 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3426 glpD -1.1 -5.7 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0890 ftsK -1.1 -6.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1777 b1777 -1.1 -1.8 orf, hypothetical protein (VIMSS) compare
b3649 rpoZ -1.0 -3.2 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3198 kdsC -1.0 -2.3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b2567 rnc -1.0 -1.8 ribonuclease III (NCBI) compare
b3871 bipA -1.0 -7.0 GTP-binding protein (NCBI) compare
b3237 argR -1.0 -4.6 arginine repressor (NCBI) compare
b1291 sapD -1.0 -2.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0722 sdhD -1.0 -4.1 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b2283 nuoG -1.0 -5.7 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b4441 glmY -1.0 -1.8 sRNA activator of glmS mRNA (RefSeq) compare
b3619 rfaD -1.0 -3.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2277 nuoM -1.0 -4.6 NADH dehydrogenase subunit M (NCBI) compare
b1286 rnb -1.0 -3.0 exoribonuclease II (NCBI) compare
b2830 nudH -1.0 -1.8 dinucleoside polyphosphate hydrolase (NCBI) compare
b3778 rep -1.0 -6.1 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2058 wcaB -1.0 -1.3 predicted acyl transferase (NCBI) compare
b4577 sgrS -1.0 -2.2 small antisense RNA (NCBI) compare
b3082 ygjM -1.0 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b2278 nuoL -1.0 -6.0 NADH dehydrogenase subunit L (NCBI) compare
b3811 xerC -0.9 -2.9 site-specific tyrosine recombinase XerC (NCBI) compare
b4418 sraB -0.9 -1.5 unknown RNA (NCBI) compare
b1848 yebG -0.9 -1.6 conserved protein regulated by LexA (NCBI) compare
b4234 yjgA -0.9 -3.0 hypothetical protein (NCBI) compare
b2286 nuoC -0.9 -4.6 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3616 tdh -0.9 -3.9 L-threonine 3-dehydrogenase (NCBI) compare
b2363 yfdT -0.9 -1.8 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b4172 hfq -0.9 -1.4 RNA-binding protein Hfq (NCBI) compare
b3621 rfaC -0.9 -4.4 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2318 truA -0.9 -3.6 tRNA pseudouridine synthase A (NCBI) compare
b0724 sdhB -0.9 -4.7 succinate dehydrogenase, FeS subunit (NCBI) compare
b2287 nuoB -0.9 -3.4 NADH dehydrogenase subunit B (NCBI) compare
b0053 surA -0.9 -4.2 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0049 apaH -0.9 -4.2 diadenosinetetraphosphatase (NCBI) compare
b3386 rpe -0.9 -1.7 ribulose-phosphate 3-epimerase (NCBI) compare
b2518 ndk -0.9 -2.6 nucleoside diphosphate kinase (NCBI) compare
b2282 nuoH -0.9 -2.7 NADH dehydrogenase subunit H (NCBI) compare
b0114 aceE -0.9 -2.3 pyruvate dehydrogenase subunit E1 (NCBI) compare
b2948 yqgE -0.9 -2.3 orf, hypothetical protein (VIMSS) compare
b0088 murD -0.8 -1.8 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b2284 nuoF -0.8 -4.0 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b4163 glyV -0.8 -1.8 tRNA-Gly (NCBI) compare
b0721 sdhC -0.8 -3.8 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b0928 aspC -0.8 -4.8 aspartate aminotransferase, PLP-dependent (NCBI) compare
b0439 lon -0.8 -3.6 DNA-binding ATP-dependent protease La (NCBI) compare
b3727 pstC -0.8 -3.9 phosphate transporter subunit (NCBI) compare
b1236 galU -0.8 -4.0 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0051 ksgA -0.8 -4.0 dimethyladenosine transferase (NCBI) compare
b4239 treC -0.8 -3.7 trehalose-6-P hydrolase (NCBI) compare
b3229 sspA -0.8 -2.7 stringent starvation protein A (NCBI) compare
b3792 wzxE -0.8 -4.5 O-antigen translocase (NCBI) compare
b2479 gcvR -0.8 -3.4 transcriptional regulation of gcv operon (VIMSS) compare
b2183 rsuA -0.8 -2.8 16S rRNA pseudouridylate 516 synthase (NCBI) compare
b1551 b1551 -0.8 -1.8 orf, hypothetical protein (VIMSS) compare
b2017 yefM -0.8 -1.6 orf, hypothetical protein (VIMSS) compare
b3204 ptsN -0.7 -3.1 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0222 lpcA -0.7 -2.2 phosphoheptose isomerase (NCBI) compare
b3035 tolC -0.7 -4.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3169 nusA -0.7 -2.1 transcription elongation factor NusA (NCBI) compare
b0683 fur -0.7 -1.8 ferric uptake regulator (NCBI) compare
b1084 rne -0.7 -3.4 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b2325 yfcL -0.7 -3.0 hypothetical protein (NCBI) compare
b3844 fre -0.7 -3.6 NAD(P)H-flavin reductase (NCBI) compare
b3164 pnp -0.7 -2.5 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0357 yaiN -0.7 -2.0 putative alpha helix chain (VIMSS) compare
b3806 cyaA -0.7 -3.3 adenylate cyclase (NCBI) compare
b1231 tyrT -0.7 -1.0 tRNA-Tyr (NCBI) compare
b2259 pmrD -0.7 -1.3 polymyxin resistance protein B (VIMSS) compare
b4158 yjeO -0.7 -1.6 conserved inner membrane protein (NCBI) compare
b4414 tff -0.7 -1.4 unknown RNA (NCBI) compare
b3706 trmE -0.7 -4.0 tRNA modification GTPase (NCBI) compare
b0080 fruR -0.7 -3.8 DNA-binding transcriptional dual regulator (NCBI) compare
b3500 gor -0.7 -1.3 glutathione reductase (NCBI) compare
b3236 mdh -0.7 -4.3 malate dehydrogenase (NCBI) compare
b2288 nuoA -0.7 -1.7 NADH dehydrogenase I chain A (VIMSS) compare
b3238 yhcN -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b3052 rfaE -0.6 -3.0 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1126 potA -0.6 -3.8 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b2646 ypjF -0.6 -1.4 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b1667 ydhR -0.6 -1.0 hypothetical protein (NCBI) compare
b0471 ybaB -0.6 -2.4 hypothetical protein (NCBI) compare
b1213 ychQ -0.6 -2.2 predicted transcriptional regulator (NCBI) compare
b0723 sdhA -0.6 -4.4 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0432 cyoA -0.6 -3.9 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3462 ftsX -0.6 -2.7 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2424 cysU -0.6 -1.9 sulfate/thiosulfate transporter subunit (NCBI) compare
b3341 rpsG -0.6 -1.0 30S ribosomal protein S7 (NCBI) compare
b2895 fldB -0.6 -2.0 flavodoxin 2 (NCBI) compare
b0429 cyoD -0.6 -2.9 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b4139 aspA -0.6 -3.8 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b0428 cyoE -0.6 -3.4 protoheme IX farnesyltransferase (NCBI) compare
b1480 sra -0.6 -1.7 30S ribosomal subunit protein S22 (NCBI) compare
b0001 thrL -0.6 -1.3 thr operon leader peptide (NCBI) compare
b3761 trpT -0.6 -1.2 tRNA-Trp (NCBI) compare
b1676 pykF -0.6 -2.6 pyruvate kinase (NCBI) compare
b1252 tonB -0.6 -2.2 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b2297 pta -0.6 -1.2 phosphate acetyltransferase (NCBI) compare
b3726 pstA -0.6 -2.8 phosphate transporter subunit (NCBI) compare
b2444 yffM -0.6 -1.0 CPZ-55 prophage; predicted protein (NCBI) compare
b0340 cynS -0.6 -2.0 cyanate hydratase (NCBI) compare
b2450 yffS -0.6 -1.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b4179 vacB -0.6 -3.5 putative enzyme (VIMSS) compare
b1677 lpp -0.6 -1.1 murein lipoprotein (NCBI) compare
b0720 gltA -0.6 -2.8 citrate synthase (NCBI) compare
b1963 b1963 -0.6 -2.3 orf, hypothetical protein (VIMSS) compare
b0113 pdhR -0.6 -2.4 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b1989 asnV -0.6 -1.7 tRNA-Asn (NCBI) compare
b1124 potC -0.6 -3.3 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4208 cycA -0.6 -4.1 D-alanine/D-serine/glycine transporter (NCBI) compare
b3398 yrfF -0.6 -1.6 predicted inner membrane protein (NCBI) compare
b4215 ytfI -0.5 -2.1 hypothetical protein (NCBI) compare
b3613 yibP -0.5 -2.9 putative membrane protein (VIMSS) compare
b1412 azoR -0.5 -1.7 acyl carrier protein phosphodiesterase (NCBI) compare
b0191 yaeJ -0.5 -1.9 hypothetical protein (NCBI) compare
b3631 rfaG -0.5 -4.7 glucosyltransferase I (NCBI) compare
b3609 secB -0.5 -2.3 export protein SecB (NCBI) compare
b4679 yohP -0.5 -2.3 expressed protein (RefSeq) compare
b3807 cyaY -0.5 -3.3 frataxin-like protein (NCBI) compare
b3617 kbl -0.5 -2.9 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b2531 iscR -0.5 -1.3 DNA-binding transcriptional repressor (NCBI) compare
b0481 ybaK -0.5 -1.4 hypothetical protein (NCBI) compare
b2393 nupC -0.5 -3.0 nucleoside (except guanosine) transporter (NCBI) compare
b3228 sspB -0.5 -1.7 ClpXP protease specificity-enhancing factor (NCBI) compare
b1390 paaC -0.5 -2.2 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b4546 ypeB -0.5 -0.9 hypothetical protein (NCBI) compare
b2906 visC -0.5 -3.0 hypothetical protein (NCBI) compare
b0728 sucC -0.5 -2.9 succinyl-CoA synthetase subunit beta (NCBI) compare
b1874 cutC -0.5 -2.4 copper homeostasis protein (NCBI) compare
b1949 fliQ -0.5 -1.4 flagellar biosynthesis protein Q (NCBI) compare
b2897 ygfY -0.5 -1.3 hypothetical protein (NCBI) compare
b1095 fabF -0.5 -3.1 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3026 qseC -0.5 -2.3 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2280 nuoJ -0.5 -2.7 NADH dehydrogenase subunit J (NCBI) compare
b2990 hybG -0.5 -1.0 hydrogenase 2 accessory protein (NCBI) compare
b0825 mipB -0.5 -1.5 putative transaldolase (VIMSS) compare
b3107 yhaL -0.5 -1.0 orf, hypothetical protein (VIMSS) compare
b3289 rsmB -0.5 -3.5 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) compare
b0729 sucD -0.5 -1.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1062 pyrC -0.5 -2.9 dihydroorotase (NCBI) compare
b0437 clpP -0.5 -3.1 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0784 moaD -0.5 -1.3 molybdopterin synthase, small subunit (NCBI) compare
b2892 recJ -0.5 -3.2 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b0767 ybhE -0.5 -1.5 6-phosphogluconolactonase (NCBI) compare
b4042 dgkA -0.5 -1.6 diacylglycerol kinase (NCBI) compare
b1187 fadR -0.5 -2.2 fatty acid metabolism regulator (NCBI) compare
b3483 yhhH -0.5 -0.7 orf, hypothetical protein (VIMSS) compare
b1865 nudB -0.5 -1.2 dATP pyrophosphohydrolase (NCBI) compare
b3935 priA -0.5 -0.8 primosome assembly protein PriA (NCBI) compare
b1370 insH-5 -0.5 -1.0 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3071 yqjI -0.5 -2.2 predicted transcriptional regulator (NCBI) compare
b4255 yjgD -0.5 -2.1 hypothetical protein (NCBI) compare
b1863 ruvC -0.5 -1.9 Holliday junction resolvase (NCBI) compare
b2498 upp -0.5 -1.8 uracil phosphoribosyltransferase (VIMSS) compare
b3866 yihI -0.5 -2.3 hypothetical protein (NCBI) compare
b0739 tolA -0.5 -2.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2187 yejL -0.4 -1.6 hypothetical protein (NCBI) compare
b3630 rfaP -0.4 -3.5 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3493 pitA -0.4 -3.0 phosphate transporter, low-affinity (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments