Experiment set4IT055 for Escherichia coli BW25113

Compare to:

LB with decyl alcohol 5 vol%

200 most important genes:

  gene name fitness t score description  
b0462 acrB -7.0 -12.6 multidrug efflux system protein (NCBI) compare
b0463 acrA -7.0 -8.3 multidrug efflux system (NCBI) compare
b3035 tolC -6.4 -6.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3198 kdsC -6.3 -6.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3631 rfaG -6.1 -11.0 glucosyltransferase I (NCBI) compare
b3630 rfaP -5.8 -6.9 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b0737 tolQ -5.7 -3.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2528 iscA -5.6 -3.9 iron-sulfur cluster assembly protein (NCBI) compare
b4443 gcvB -5.4 -3.7 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b1236 galU -5.4 -3.7 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3632 rfaQ -5.4 -27.9 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3842 rfaH -5.3 -5.2 transcriptional activator RfaH (NCBI) compare
b3052 rfaE -5.2 -3.6 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0222 lpcA -5.1 -3.5 phosphoheptose isomerase (NCBI) compare
b2512 yfgL -5.1 -7.7 protein assembly complex, lipoprotein component (NCBI) compare
b4172 hfq -4.8 -3.3 RNA-binding protein Hfq (NCBI) compare
b3621 rfaC -4.7 -3.3 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0688 pgm -4.7 -4.6 phosphoglucomutase (NCBI) compare
b3619 rfaD -4.7 -3.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0740 tolB -4.7 -8.4 translocation protein TolB precursor (NCBI) compare
b0053 surA -4.7 -4.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2567 rnc -4.6 -3.2 ribonuclease III (NCBI) compare
b0739 tolA -4.6 -6.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0145 dksA -4.5 -5.4 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3620 rfaF -4.3 -3.0 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3426 glpD -4.3 -10.7 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0630 lipB -4.2 -2.9 protein of lipoate biosynthesis (VIMSS) compare
b3199 yrbK -4.2 -4.0 hypothetical protein (NCBI) compare
b2935 tktA -4.1 -2.8 transketolase 1, thiamin-binding (NCBI) compare
b0738 tolR -4.0 -4.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2188 yejM -3.9 -10.9 predicted hydrolase, inner membrane (NCBI) compare
b2501 ppk -3.8 -14.4 polyphosphate kinase (NCBI) compare
b1286 rnb -3.8 -5.7 exoribonuclease II (NCBI) compare
b0741 pal -3.7 -7.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0726 sucA -3.6 -5.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b3728 pstS -3.6 -9.0 phosphate transporter subunit (NCBI) compare
b3627 rfaI -3.6 -19.4 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3844 fre -3.6 -9.2 NAD(P)H-flavin reductase (NCBI) compare
b0014 dnaK -3.6 -4.2 molecular chaperone DnaK (NCBI) compare
b0118 acnB -3.5 -5.4 aconitate hydratase (NCBI) compare
b1831 proQ -3.5 -4.5 putative solute/DNA competence effector (NCBI) compare
b3725 pstB -3.5 -4.7 phosphate transporter subunit (NCBI) compare
b2894 xerD -3.4 -3.3 site-specific tyrosine recombinase XerD (NCBI) compare
b3026 qseC -3.3 -8.8 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4375 prfC -3.3 -11.5 peptide chain release factor 3 (NCBI) compare
b1830 prc -3.1 -7.9 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b0200 gmhB -3.1 -3.0 hypothetical protein (NCBI) compare
b2282 nuoH -3.1 -5.8 NADH dehydrogenase subunit H (NCBI) compare
b2617 smpA -3.0 -6.1 small membrane protein A (VIMSS) compare
b0178 hlpA -3.0 -4.8 periplasmic chaperone (NCBI) compare
b3811 xerC -3.0 -5.4 site-specific tyrosine recombinase XerC (NCBI) compare
b3386 rpe -3.0 -2.0 ribulose-phosphate 3-epimerase (NCBI) compare
b2278 nuoL -2.9 -12.6 NADH dehydrogenase subunit L (NCBI) compare
b3628 rfaB -2.9 -17.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b3806 cyaA -2.9 -9.3 adenylate cyclase (NCBI) compare
b2281 nuoI -2.9 -5.4 NADH dehydrogenase subunit I (NCBI) compare
b2330 yfcB -2.9 -4.3 putative adenine-specific methylase (VIMSS) compare
b2284 nuoF -2.8 -8.0 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b2276 nuoN -2.8 -8.3 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2283 nuoG -2.7 -11.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2576 srmB -2.7 -6.8 ATP-dependent RNA helicase (NCBI) compare
b0724 sdhB -2.7 -8.1 succinate dehydrogenase, FeS subunit (NCBI) compare
b0114 aceE -2.6 -4.0 pyruvate dehydrogenase subunit E1 (NCBI) compare
b1855 lpxM -2.6 -8.0 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0723 sdhA -2.6 -11.8 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b1604 ydgH -2.6 -4.7 hypothetical protein (NCBI) compare
b2287 nuoB -2.6 -4.7 NADH dehydrogenase subunit B (NCBI) compare
b2280 nuoJ -2.6 -7.4 NADH dehydrogenase subunit J (NCBI) compare
b3870 glnA -2.6 -5.4 glutamine synthetase (NCBI) compare
b0683 fur -2.5 -3.1 ferric uptake regulator (NCBI) compare
b2285 nuoE -2.5 -3.9 NADH dehydrogenase subunit E (NCBI) compare
b2820 recB -2.5 -4.9 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2279 nuoK -2.5 -4.0 NADH dehydrogenase subunit K (NCBI) compare
b0949 uup -2.4 -9.3 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b2699 recA -2.4 -4.0 recombinase A (NCBI) compare
b2277 nuoM -2.4 -9.2 NADH dehydrogenase subunit M (NCBI) compare
b3163 nlpI -2.4 -6.4 hypothetical protein (NCBI) compare
b3290 trkA -2.4 -6.3 potassium transporter peripheral membrane component (NCBI) compare
b3162 deaD -2.4 -8.4 inducible ATP-independent RNA helicase (VIMSS) compare
b0547 ybcN -2.4 -2.9 DLP12 prophage; predicted protein (NCBI) compare
b2897 ygfY -2.3 -5.2 hypothetical protein (NCBI) compare
b2288 nuoA -2.3 -5.1 NADH dehydrogenase I chain A (VIMSS) compare
b2286 nuoC -2.2 -7.7 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3636 rpmG -2.2 -2.0 50S ribosomal protein L33 (NCBI) compare
b0721 sdhC -2.1 -2.9 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b3463 ftsE -2.1 -6.6 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b2784 relA -2.1 -10.2 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b3778 rep -2.0 -11.6 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1693 aroD -2.0 -9.0 3-dehydroquinate dehydratase (NCBI) compare
b0082 mraW -2.0 -4.1 S-adenosyl-methyltransferase (NCBI) compare
b0049 apaH -2.0 -7.0 diadenosinetetraphosphatase (NCBI) compare
b3414 gntY -2.0 -8.3 predicted gluconate transport associated protein (NCBI) compare
b1290 sapF -2.0 -3.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4480 hdfR -1.9 -6.6 transcriptional regulator HdfR (NCBI) compare
b2808 gcvA -1.9 -7.0 DNA-binding transcriptional dual regulator (NCBI) compare
b3169 nusA -1.9 -3.8 transcription elongation factor NusA (NCBI) compare
b3164 pnp -1.9 -5.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3625 rfaY -1.9 -12.2 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3871 bipA -1.9 -10.9 GTP-binding protein (NCBI) compare
b3341 rpsG -1.9 -2.5 30S ribosomal protein S7 (NCBI) compare
b3726 pstA -1.8 -6.1 phosphate transporter subunit (NCBI) compare
b3609 secB -1.8 -2.6 export protein SecB (NCBI) compare
b2064 asmA -1.8 -4.8 predicted assembly protein (NCBI) compare
b1130 phoP -1.8 -9.0 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3281 aroE -1.8 -12.2 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b2313 cvpA -1.8 -5.8 membrane protein required for colicin V production (NCBI) compare
b3237 argR -1.7 -6.0 arginine repressor (NCBI) compare
b3644 yicC -1.7 -5.2 hypothetical protein (NCBI) compare
b4178 yjeB -1.7 -5.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b0623 cspE -1.6 -3.2 cold shock protein E (NCBI) compare
b2830 nudH -1.6 -2.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b4234 yjgA -1.6 -5.5 hypothetical protein (NCBI) compare
b3183 obgE -1.6 -1.8 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1192 ldcA -1.6 -4.6 L,D-carboxypeptidase A (NCBI) compare
b0722 sdhD -1.6 -3.5 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b0429 cyoD -1.5 -5.7 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b4177 purA -1.5 -4.4 adenylosuccinate synthetase (NCBI) compare
b0677 nagA -1.5 -6.0 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1235 rssB -1.5 -8.3 response regulator of RpoS (NCBI) compare
b1269 rluB -1.5 -3.5 23S rRNA pseudouridylate synthase (NCBI) compare
b2297 pta -1.5 -2.3 phosphate acetyltransferase (NCBI) compare
b1658 purR -1.5 -6.0 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3150 yraP -1.5 -7.1 hypothetical protein (NCBI) compare
b0928 aspC -1.5 -7.3 aspartate aminotransferase, PLP-dependent (NCBI) compare
b1252 tonB -1.5 -4.3 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3389 aroB -1.5 -9.3 3-dehydroquinate synthase (NCBI) compare
b0471 ybaB -1.5 -4.3 hypothetical protein (NCBI) compare
b3727 pstC -1.4 -4.5 phosphate transporter subunit (NCBI) compare
b4139 aspA -1.4 -7.4 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b3462 ftsX -1.4 -6.1 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b4000 hupA -1.4 -5.7 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b3082 ygjM -1.4 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b0436 tig -1.4 -6.5 trigger factor (NCBI) compare
b0890 ftsK -1.4 -7.5 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2822 recC -1.4 -4.5 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2937 speB -1.4 -6.8 agmatinase (NCBI) compare
b4509 ylcG -1.4 -1.5 DLP12 prophage; predicted protein (NCBI) compare
b3741 gidA -1.4 -7.7 glucose-inhibited division protein A (NCBI) compare
b3195 yrbF -1.4 -8.4 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b2498 upp -1.4 -4.4 uracil phosphoribosyltransferase (VIMSS) compare
b3390 aroK -1.4 -2.2 shikimate kinase I (NCBI) compare
b0428 cyoE -1.3 -6.5 protoheme IX farnesyltransferase (NCBI) compare
b2572 rseA -1.3 -2.2 anti-sigma factor (NCBI) compare
b4685 yrbN -1.3 -2.5 expressed protein (RefSeq) compare
b1129 phoQ -1.3 -7.5 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b0957 ompA -1.3 -4.4 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3192 yrbC -1.3 -8.0 predicted ABC-type organic solvent transporter (NCBI) compare
b0080 fruR -1.3 -5.9 DNA-binding transcriptional dual regulator (NCBI) compare
b3194 yrbE -1.3 -8.3 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0439 lon -1.3 -5.3 DNA-binding ATP-dependent protease La (NCBI) compare
b2346 vacJ -1.3 -6.9 predicted lipoprotein (NCBI) compare
b2431 b2431 -1.3 -7.3 orf, hypothetical protein (VIMSS) compare
b2689 yqaA -1.3 -4.1 conserved inner membrane protein (NCBI) compare
b4042 dgkA -1.3 -3.8 diacylglycerol kinase (NCBI) compare
b1531 marA -1.3 -3.7 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b1248 b1248 -1.2 -2.9 orf, hypothetical protein (VIMSS) compare
b0728 sucC -1.2 -4.8 succinyl-CoA synthetase subunit beta (NCBI) compare
b0430 cyoC -1.2 -3.5 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b4239 treC -1.2 -4.6 trehalose-6-P hydrolase (NCBI) compare
b3649 rpoZ -1.2 -3.7 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3764 yifE -1.2 -4.7 hypothetical protein (NCBI) compare
b3706 trmE -1.2 -6.0 tRNA modification GTPase (NCBI) compare
b3166 truB -1.1 -4.9 tRNA pseudouridine synthase B (NCBI) compare
b3916 pfkA -1.1 -4.1 6-phosphofructokinase (NCBI) compare
b0548 ninE -1.1 -1.2 DLP12 prophage; conserved protein (NCBI) compare
b1123 potD -1.1 -4.7 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b0720 gltA -1.1 -4.5 citrate synthase (NCBI) compare
b0008 talB -1.1 -5.7 transaldolase B (NCBI) compare
b2569 lepA -1.1 -4.4 GTP-binding protein LepA (NCBI) compare
b3193 yrbD -1.1 -6.8 predicted ABC-type organic solvent transporter (NCBI) compare
b2340 sixA -1.1 -4.2 phosphohistidine phosphatase (NCBI) compare
b4062 soxS -1.1 -2.3 DNA-binding transcriptional dual regulator (NCBI) compare
b4179 vacB -1.1 -6.6 putative enzyme (VIMSS) compare
b4410 ecnA -1.1 -1.5 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b2620 smpB -1.1 -1.9 SsrA-binding protein (NCBI) compare
b3962 udhA -1.0 -6.7 putative oxidoreductase (VIMSS) compare
b3398 yrfF -1.0 -2.8 predicted inner membrane protein (NCBI) compare
b1860 ruvB -1.0 -2.1 Holliday junction DNA helicase B (NCBI) compare
b3236 mdh -1.0 -5.5 malate dehydrogenase (NCBI) compare
b1551 b1551 -1.0 -2.3 orf, hypothetical protein (VIMSS) compare
b3210 arcB -1.0 -5.8 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b0888 trxB -1.0 -3.1 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3807 cyaY -1.0 -4.1 frataxin-like protein (NCBI) compare
b3247 cafA -1.0 -7.0 bundles of cytoplasmic filaments (VIMSS) compare
b0866 ybjQ -1.0 -1.3 hypothetical protein (NCBI) compare
b1292 sapC -1.0 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0432 cyoA -1.0 -6.7 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3363 ppiA -1.0 -5.8 peptidyl-prolyl cis-trans isomerase A (rotamase A) (NCBI) compare
b2948 yqgE -1.0 -2.9 orf, hypothetical protein (VIMSS) compare
b4585 sroB -1.0 -1.3 Novel sRNA, function unknown (RefSeq) compare
b1294 sapA -1.0 -5.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4203 rplI -1.0 -3.4 50S ribosomal protein L9 (NCBI) compare
b1676 pykF -1.0 -3.9 pyruvate kinase (NCBI) compare
b3191 yrbB -0.9 -6.0 orf, hypothetical protein (VIMSS) compare
b0952 ymbA -0.9 -3.8 conserved protein (RefSeq) compare
b1594 dgsA -0.9 -3.8 DNA-binding transcriptional repressor (NCBI) compare
b2895 fldB -0.9 -2.7 flavodoxin 2 (NCBI) compare
b0729 sucD -0.9 -2.7 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1293 sapB -0.9 -1.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0431 cyoB -0.9 -6.3 cytochrome o ubiquinol oxidase subunit I (NCBI) compare


Specific Phenotypes

For 2 genes in this experiment

For stress decyl alcohol in Escherichia coli BW25113

For stress decyl alcohol across organisms