Experiment set4IT040 for Escherichia coli BW25113

Compare to:

LB with undecene 5 vol%

200 most important genes:

  gene name fitness t score description  
b0462 acrB -6.4 -7.6 multidrug efflux system protein (NCBI) compare
b0463 acrA -6.1 -8.4 multidrug efflux system (NCBI) compare
b3035 tolC -5.7 -4.0 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2494 yfgC -5.4 -9.0 predicted peptidase (NCBI) compare
b3961 oxyR -5.4 -13.1 DNA-binding transcriptional dual regulator (NCBI) compare
b3627 rfaI -5.4 -14.4 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3199 yrbK -5.3 -3.6 hypothetical protein (NCBI) compare
b3632 rfaQ -5.3 -19.9 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3628 rfaB -5.2 -16.4 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b1129 phoQ -5.2 -11.5 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b2392 mntH -5.2 -8.6 manganese transport protein MntH (NCBI) compare
b3195 yrbF -5.1 -12.4 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1130 phoP -5.1 -10.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0431 cyoB -5.1 -9.7 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3631 rfaG -5.0 -13.4 glucosyltransferase I (NCBI) compare
b3792 wzxE -5.0 -6.9 O-antigen translocase (NCBI) compare
b3192 yrbC -5.0 -11.1 predicted ABC-type organic solvent transporter (NCBI) compare
b0427 yajR -4.9 -11.0 putative transport protein (VIMSS) compare
b3193 yrbD -4.9 -12.7 predicted ABC-type organic solvent transporter (NCBI) compare
b0429 cyoD -4.9 -6.6 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0683 fur -4.9 -3.3 ferric uptake regulator (NCBI) compare
b3194 yrbE -4.8 -14.6 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b0432 cyoA -4.7 -12.2 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b3630 rfaP -4.7 -7.1 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1604 ydgH -4.7 -6.1 hypothetical protein (NCBI) compare
b1863 ruvC -4.6 -4.4 Holliday junction resolvase (NCBI) compare
b2346 vacJ -4.5 -10.5 predicted lipoprotein (NCBI) compare
b3026 qseC -4.5 -4.4 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b3842 rfaH -4.5 -5.4 transcriptional activator RfaH (NCBI) compare
b1236 galU -4.5 -4.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0428 cyoE -4.5 -9.1 protoheme IX farnesyltransferase (NCBI) compare
b0430 cyoC -4.5 -5.3 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b2016 yeeZ -4.5 -9.9 predicted epimerase, with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b0145 dksA -4.4 -3.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4480 hdfR -4.4 -7.9 transcriptional regulator HdfR (NCBI) compare
b2436 hemF -4.4 -6.7 coproporphyrinogen III oxidase (NCBI) compare
b0222 lpcA -4.0 -2.8 phosphoheptose isomerase (NCBI) compare
b2512 yfgL -3.9 -8.6 protein assembly complex, lipoprotein component (NCBI) compare
b2699 recA -3.8 -2.6 recombinase A (NCBI) compare
b3052 rfaE -3.8 -5.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3728 pstS -3.8 -5.8 phosphate transporter subunit (NCBI) compare
b3811 xerC -3.8 -2.6 site-specific tyrosine recombinase XerC (NCBI) compare
b1861 ruvA -3.7 -3.6 Holliday junction DNA helicase motor protein (NCBI) compare
b3764 yifE -3.7 -7.5 hypothetical protein (NCBI) compare
b4172 hfq -3.7 -3.6 RNA-binding protein Hfq (NCBI) compare
b0739 tolA -3.7 -6.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3620 rfaF -3.7 -2.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0053 surA -3.6 -3.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3621 rfaC -3.6 -2.5 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3619 rfaD -3.6 -2.5 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0677 nagA -3.6 -9.2 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b2784 relA -3.5 -13.0 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b4000 hupA -3.4 -6.2 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b0738 tolR -3.4 -3.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0200 gmhB -3.4 -2.3 hypothetical protein (NCBI) compare
b3191 yrbB -3.3 -12.8 orf, hypothetical protein (VIMSS) compare
b3198 kdsC -3.3 -5.3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b2498 upp -3.3 -5.3 uracil phosphoribosyltransferase (VIMSS) compare
b3625 rfaY -3.2 -16.2 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1839 yebY -3.2 -5.6 hypothetical protein (NCBI) compare
b3725 pstB -3.2 -3.1 phosphate transporter subunit (NCBI) compare
b2567 rnc -3.2 -3.0 ribonuclease III (NCBI) compare
b0737 tolQ -3.1 -4.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1677 lpp -3.1 -5.1 murein lipoprotein (NCBI) compare
b2894 xerD -3.1 -3.0 site-specific tyrosine recombinase XerD (NCBI) compare
b0890 ftsK -3.1 -10.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3398 yrfF -3.0 -5.0 predicted inner membrane protein (NCBI) compare
b0688 pgm -3.0 -5.7 phosphoglucomutase (NCBI) compare
b2830 nudH -3.0 -2.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b4025 pgi -2.9 -12.2 glucose-6-phosphate isomerase (NCBI) compare
b1860 ruvB -2.9 -1.9 Holliday junction DNA helicase B (NCBI) compare
b2906 visC -2.8 -8.9 hypothetical protein (NCBI) compare
b0605 ahpC -2.7 -7.3 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b3226 yhcK -2.7 -8.8 putative FADA-type transcriptional regulator (VIMSS) compare
b2820 recB -2.7 -3.6 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0957 ompA -2.7 -4.8 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2188 yejM -2.6 -10.7 predicted hydrolase, inner membrane (NCBI) compare
b2808 gcvA -2.6 -8.9 DNA-binding transcriptional dual regulator (NCBI) compare
b4585 sroB -2.6 -2.1 Novel sRNA, function unknown (RefSeq) compare
b3839 tatC -2.5 -11.7 TatABCE protein translocation system subunit (NCBI) compare
b4443 gcvB -2.5 -1.7 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b4146 yjeK -2.5 -6.1 predicted lysine aminomutase (NCBI) compare
b3844 fre -2.5 -8.5 NAD(P)H-flavin reductase (NCBI) compare
b3726 pstA -2.5 -7.4 phosphate transporter subunit (NCBI) compare
b4441 glmY -2.5 -2.4 sRNA activator of glmS mRNA (RefSeq) compare
b0740 tolB -2.5 -7.8 translocation protein TolB precursor (NCBI) compare
b2286 nuoC -2.5 -7.6 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3341 rpsG -2.4 -2.3 30S ribosomal protein S7 (NCBI) compare
b0082 mraW -2.4 -5.1 S-adenosyl-methyltransferase (NCBI) compare
b0759 galE -2.4 -8.0 UDP-galactose-4-epimerase (VIMSS) compare
b3778 rep -2.4 -12.4 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1831 proQ -2.3 -5.9 putative solute/DNA competence effector (NCBI) compare
b2897 ygfY -2.3 -4.9 hypothetical protein (NCBI) compare
b4177 purA -2.3 -5.9 adenylosuccinate synthetase (NCBI) compare
b2620 smpB -2.3 -3.8 SsrA-binding protein (NCBI) compare
b0471 ybaB -2.2 -4.2 hypothetical protein (NCBI) compare
b0676 nagC -2.1 -10.6 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b0440 hupB -2.1 -5.1 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b1830 prc -2.1 -7.9 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b2276 nuoN -2.1 -8.4 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2281 nuoI -2.1 -4.4 NADH dehydrogenase subunit I (NCBI) compare
b1286 rnb -2.1 -4.7 exoribonuclease II (NCBI) compare
b2284 nuoF -2.1 -6.4 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b2280 nuoJ -2.1 -6.5 NADH dehydrogenase subunit J (NCBI) compare
b2330 yfcB -2.0 -3.9 putative adenine-specific methylase (VIMSS) compare
b3386 rpe -2.0 -1.4 ribulose-phosphate 3-epimerase (NCBI) compare
b3169 nusA -2.0 -4.3 transcription elongation factor NusA (NCBI) compare
b2277 nuoM -2.0 -8.3 NADH dehydrogenase subunit M (NCBI) compare
b3727 pstC -2.0 -8.4 phosphate transporter subunit (NCBI) compare
b2283 nuoG -1.9 -9.0 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3197 kdsD -1.9 -8.5 D-arabinose 5-phosphate isomerase (NCBI) compare
b1712 ihfA -1.9 -4.3 integration host factor subunit alpha (NCBI) compare
b2424 cysU -1.9 -3.8 sulfate/thiosulfate transporter subunit (NCBI) compare
b2822 recC -1.9 -7.1 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b3237 argR -1.9 -7.1 arginine repressor (NCBI) compare
b3387 dam -1.9 -13.2 DNA adenine methylase (NCBI) compare
b1531 marA -1.8 -4.0 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b0721 sdhC -1.8 -6.4 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b4557 yidD -1.8 -4.8 hypothetical protein (NCBI) compare
b0723 sdhA -1.8 -10.9 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0049 apaH -1.8 -6.6 diadenosinetetraphosphatase (NCBI) compare
b3636 rpmG -1.7 -3.0 50S ribosomal protein L33 (NCBI) compare
b2287 nuoB -1.7 -5.2 NADH dehydrogenase subunit B (NCBI) compare
b1594 dgsA -1.7 -6.4 DNA-binding transcriptional repressor (NCBI) compare
b4042 dgkA -1.7 -4.7 diacylglycerol kinase (NCBI) compare
b0406 tgt -1.7 -7.4 queuine tRNA-ribosyltransferase (NCBI) compare
b3210 arcB -1.7 -8.5 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b2278 nuoL -1.7 -10.2 NADH dehydrogenase subunit L (NCBI) compare
b4698 mgrR -1.7 -2.7 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b3242 yhcR -1.7 -3.8 orf, hypothetical protein (VIMSS) compare
b1855 lpxM -1.7 -5.4 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0741 pal -1.7 -4.4 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0724 sdhB -1.6 -7.0 succinate dehydrogenase, FeS subunit (NCBI) compare
b2617 smpA -1.6 -3.5 small membrane protein A (VIMSS) compare
b4396 rob -1.6 -8.4 DNA-binding transcriptional activator (NCBI) compare
b3150 yraP -1.6 -6.4 hypothetical protein (NCBI) compare
b2282 nuoH -1.6 -4.0 NADH dehydrogenase subunit H (NCBI) compare
b3075 ebgR -1.6 -6.3 DNA-binding transcriptional repressor (NCBI) compare
b4416 rybA -1.6 -1.6 unknown RNA (NCBI) compare
b2279 nuoK -1.5 -2.9 NADH dehydrogenase subunit K (NCBI) compare
b2501 ppk -1.5 -9.2 polyphosphate kinase (NCBI) compare
b4155 yjeA -1.5 -2.0 putative lysyl-tRNA synthetase (VIMSS) compare
b0726 sucA -1.5 -4.6 alpha-ketoglutarate decarboxylase (NCBI) compare
b1658 purR -1.5 -7.1 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b0226 dinJ -1.5 -2.0 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b0623 cspE -1.5 -2.0 cold shock protein E (NCBI) compare
b2288 nuoA -1.5 -3.6 NADH dehydrogenase I chain A (VIMSS) compare
b0729 sucD -1.5 -3.1 succinyl-CoA synthetase subunit alpha (NCBI) compare
b2554 yfhA -1.5 -7.9 predicted DNA-binding response regulator in two-component system (NCBI) compare
b3609 secB -1.5 -1.6 export protein SecB (NCBI) compare
b4139 aspA -1.5 -9.1 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b0014 dnaK -1.5 -2.5 molecular chaperone DnaK (NCBI) compare
b0728 sucC -1.4 -6.3 succinyl-CoA synthetase subunit beta (NCBI) compare
b4402 yjjY -1.4 -2.2 hypothetical protein (NCBI) compare
b4509 ylcG -1.4 -1.4 DLP12 prophage; predicted protein (NCBI) compare
b3042 b3042 -1.4 -2.1 orf, hypothetical protein (VIMSS) compare
b2528 iscA -1.4 -2.5 iron-sulfur cluster assembly protein (NCBI) compare
b1840 yebZ -1.4 -5.4 predicted inner membrane protein (NCBI) compare
b4191 ulaR -1.4 -5.1 DNA-binding transcriptional dual regulator (NCBI) compare
b1162 ycgE -1.4 -5.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b3261 fis -1.4 -3.3 DNA-binding protein Fis (NCBI) compare
b2937 speB -1.4 -6.7 agmatinase (NCBI) compare
b1693 aroD -1.4 -7.3 3-dehydroquinate dehydratase (NCBI) compare
b0812 dps -1.3 -6.3 DNA protection during starvation conditions (NCBI) compare
b4515 ybgT -1.3 -2.0 hypothetical protein (NCBI) compare
b3281 aroE -1.3 -9.2 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b3032 cpdA -1.3 -6.2 cyclic 3',5'-adenosine monophosphate phosphodiesterase (NCBI) compare
b3755 yieP -1.3 -5.8 predicted transcriptional regulator (NCBI) compare
b2285 nuoE -1.3 -1.9 NADH dehydrogenase subunit E (NCBI) compare
b0209 yafD -1.3 -4.9 hypothetical protein (NCBI) compare
b0149 mrcB -1.2 -9.4 penicillin-binding protein 1b (NCBI) compare
b3926 glpK -1.2 -10.0 glycerol kinase (NCBI) compare
b3935 priA -1.2 -2.6 primosome assembly protein PriA (NCBI) compare
b3644 yicC -1.2 -5.8 hypothetical protein (NCBI) compare
b0722 sdhD -1.2 -3.8 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b3870 glnA -1.2 -3.4 glutamine synthetase (NCBI) compare
b2064 asmA -1.2 -5.0 predicted assembly protein (NCBI) compare
b3463 ftsE -1.2 -4.1 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3963 fabR -1.2 -7.2 DNA-binding transcriptional repressor (RefSeq) compare
b2555 yfhG -1.2 -5.9 hypothetical protein (NCBI) compare
b4505 insX -1.2 -1.8 predicted IS protein (RefSeq) compare
b1105 ycfM -1.2 -3.8 predicted outer membrane lipoprotein (NCBI) compare
b3784 rfe -1.2 -8.2 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1841 yobA -1.2 -1.8 hypothetical protein (NCBI) compare
b2313 cvpA -1.2 -3.6 membrane protein required for colicin V production (NCBI) compare
b1235 rssB -1.2 -6.7 response regulator of RpoS (NCBI) compare
b3613 yibP -1.1 -5.3 putative membrane protein (VIMSS) compare
b0472 recR -1.1 -5.7 recombination protein RecR (NCBI) compare
b3652 recG -1.1 -7.7 ATP-dependent DNA helicase (NCBI) compare
b0780 ybhK -1.1 -4.9 predicted transferase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b0547 ybcN -1.1 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b3860 dsbA -1.1 -5.8 periplasmic protein disulfide isomerase I (NCBI) compare
b0548 ninE -1.0 -1.8 DLP12 prophage; conserved protein (NCBI) compare
b2892 recJ -1.0 -6.2 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b4239 treC -1.0 -4.9 trehalose-6-P hydrolase (NCBI) compare
b3389 aroB -1.0 -5.9 3-dehydroquinate synthase (NCBI) compare
b1642 slyA -1.0 -1.7 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b2614 grpE -1.0 -2.3 heat shock protein (NCBI) compare
b2168 fruK -1.0 -2.2 1-phosphofructokinase (NCBI) compare
b3700 recF -1.0 -6.8 recombination protein F (NCBI) compare


Specific Phenotypes

For 23 genes in this experiment

For stress undecene in Escherichia coli BW25113

For stress undecene across organisms