Experiment set4IT037 for Escherichia coli BW25113

Compare to:

LB with ethyl acetate 5 vol%

200 most important genes:

  gene name fitness t score description  
b4042 dgkA -4.1 -4.0 diacylglycerol kinase (NCBI) compare
b3979 thrT -4.1 -2.2 tRNA-Thr (NCBI) compare
b3398 yrfF -3.6 -4.8 predicted inner membrane protein (NCBI) compare
b0161 degP -3.5 -9.0 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b0430 cyoC -3.4 -6.0 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b3463 ftsE -3.4 -5.1 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0200 gmhB -3.4 -2.3 hypothetical protein (NCBI) compare
b4375 prfC -3.3 -9.7 peptide chain release factor 3 (NCBI) compare
b3609 secB -3.3 -6.4 export protein SecB (NCBI) compare
b1292 sapC -3.3 -4.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0630 lipB -3.2 -3.0 protein of lipoate biosynthesis (VIMSS) compare
b3725 pstB -3.1 -3.0 phosphate transporter subunit (NCBI) compare
b3912 cpxR -3.1 -12.6 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b3619 rfaD -3.1 -4.7 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0428 cyoE -3.1 -9.9 protoheme IX farnesyltransferase (NCBI) compare
b2330 yfcB -3.1 -4.1 putative adenine-specific methylase (VIMSS) compare
b3621 rfaC -3.0 -6.4 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2894 xerD -3.0 -2.8 site-specific tyrosine recombinase XerD (NCBI) compare
b1293 sapB -2.9 -3.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4172 hfq -2.9 -3.3 RNA-binding protein Hfq (NCBI) compare
b0429 cyoD -2.9 -7.2 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b1236 galU -2.8 -8.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3290 trkA -2.8 -4.2 potassium transporter peripheral membrane component (NCBI) compare
b0053 surA -2.8 -7.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1095 fabF -2.7 -10.5 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b0740 tolB -2.7 -8.1 translocation protein TolB precursor (NCBI) compare
b3052 rfaE -2.7 -6.9 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0739 tolA -2.7 -6.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4177 purA -2.6 -5.2 adenylosuccinate synthetase (NCBI) compare
b0222 lpcA -2.6 -3.9 phosphoheptose isomerase (NCBI) compare
b2830 nudH -2.6 -2.5 dinucleoside polyphosphate hydrolase (NCBI) compare
b0431 cyoB -2.6 -13.2 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3162 deaD -2.6 -8.1 inducible ATP-independent RNA helicase (VIMSS) compare
b3839 tatC -2.6 -10.9 TatABCE protein translocation system subunit (NCBI) compare
b3620 rfaF -2.5 -6.8 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3631 rfaG -2.5 -17.9 glucosyltransferase I (NCBI) compare
b0738 tolR -2.4 -4.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0439 lon -2.4 -7.5 DNA-binding ATP-dependent protease La (NCBI) compare
b3613 yibP -2.3 -8.0 putative membrane protein (VIMSS) compare
b3169 nusA -2.3 -4.0 transcription elongation factor NusA (NCBI) compare
b0726 sucA -2.3 -5.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b2285 nuoE -2.3 -3.3 NADH dehydrogenase subunit E (NCBI) compare
b2699 recA -2.2 -3.6 recombinase A (NCBI) compare
b0432 cyoA -2.2 -10.5 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b2280 nuoJ -2.2 -7.3 NADH dehydrogenase subunit J (NCBI) compare
b3849 trkH -2.2 -12.9 potassium transporter (NCBI) compare
b2284 nuoF -2.2 -6.7 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1291 sapD -2.2 -3.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2286 nuoC -2.2 -7.8 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3860 dsbA -2.1 -10.9 periplasmic protein disulfide isomerase I (NCBI) compare
b0118 acnB -2.1 -4.9 aconitate hydratase (NCBI) compare
b0890 ftsK -2.1 -10.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3838 tatB -2.1 -8.9 sec-independent translocase (NCBI) compare
b2287 nuoB -2.1 -5.8 NADH dehydrogenase subunit B (NCBI) compare
b0437 clpP -2.0 -8.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b1185 dsbB -2.0 -4.2 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b3462 ftsX -2.0 -7.8 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3842 rfaH -2.0 -6.7 transcriptional activator RfaH (NCBI) compare
b0149 mrcB -1.9 -12.9 penicillin-binding protein 1b (NCBI) compare
b3204 ptsN -1.9 -6.8 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2279 nuoK -1.9 -3.0 NADH dehydrogenase subunit K (NCBI) compare
b3844 fre -1.9 -7.3 NAD(P)H-flavin reductase (NCBI) compare
b0721 sdhC -1.9 -6.4 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b3630 rfaP -1.9 -12.2 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b2281 nuoI -1.9 -4.2 NADH dehydrogenase subunit I (NCBI) compare
b2935 tktA -1.9 -4.2 transketolase 1, thiamin-binding (NCBI) compare
b3390 aroK -1.8 -2.8 shikimate kinase I (NCBI) compare
b0438 clpX -1.8 -8.6 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2688 gshA -1.8 -7.9 glutamate--cysteine ligase (NCBI) compare
b2277 nuoM -1.8 -7.7 NADH dehydrogenase subunit M (NCBI) compare
b0720 gltA -1.8 -5.2 citrate synthase (NCBI) compare
b0049 apaH -1.8 -6.9 diadenosinetetraphosphatase (NCBI) compare
b2620 smpB -1.8 -3.7 SsrA-binding protein (NCBI) compare
b3871 bipA -1.8 -10.4 GTP-binding protein (NCBI) compare
b2297 pta -1.7 -2.2 phosphate acetyltransferase (NCBI) compare
b1290 sapF -1.7 -2.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0722 sdhD -1.7 -5.3 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b4239 treC -1.7 -6.9 trehalose-6-P hydrolase (NCBI) compare
b0427 yajR -1.7 -10.1 putative transport protein (VIMSS) compare
b1090 plsX -1.7 -6.2 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b3811 xerC -1.7 -3.7 site-specific tyrosine recombinase XerC (NCBI) compare
b2276 nuoN -1.7 -6.6 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b1109 ndh -1.7 -5.4 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b1235 rssB -1.7 -8.6 response regulator of RpoS (NCBI) compare
b2283 nuoG -1.7 -8.7 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2278 nuoL -1.7 -10.0 NADH dehydrogenase subunit L (NCBI) compare
b0688 pgm -1.7 -4.9 phosphoglucomutase (NCBI) compare
b3465 yhhF -1.6 -7.2 predicted methyltransferase (NCBI) compare
b0741 pal -1.6 -4.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3082 ygjM -1.6 -3.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3386 rpe -1.6 -1.8 ribulose-phosphate 3-epimerase (NCBI) compare
b3414 gntY -1.6 -6.7 predicted gluconate transport associated protein (NCBI) compare
b2822 recC -1.6 -6.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2906 visC -1.6 -7.1 hypothetical protein (NCBI) compare
b3426 glpD -1.6 -7.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b4146 yjeK -1.6 -5.1 predicted lysine aminomutase (NCBI) compare
b2282 nuoH -1.6 -3.7 NADH dehydrogenase subunit H (NCBI) compare
b0723 sdhA -1.6 -9.0 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b0737 tolQ -1.6 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3792 wzxE -1.5 -9.0 O-antigen translocase (NCBI) compare
b3095 yqjA -1.5 -9.2 conserved inner membrane protein (NCBI) compare
b0724 sdhB -1.5 -5.7 succinate dehydrogenase, FeS subunit (NCBI) compare
b3977 tyrU -1.5 -1.4 tRNA-Tyr (NCBI) compare
b3870 glnA -1.5 -3.5 glutamine synthetase (NCBI) compare
b3026 qseC -1.5 -6.2 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0683 fur -1.5 -2.4 ferric uptake regulator (NCBI) compare
b2947 gshB -1.5 -5.4 glutathione synthetase (NCBI) compare
b4222 ytfP -1.5 -5.8 hypothetical protein (NCBI) compare
b2567 rnc -1.4 -2.2 ribonuclease III (NCBI) compare
b3727 pstC -1.4 -7.1 phosphate transporter subunit (NCBI) compare
b3237 argR -1.4 -5.7 arginine repressor (NCBI) compare
b1105 ycfM -1.4 -4.3 predicted outer membrane lipoprotein (NCBI) compare
b3493 pitA -1.4 -8.4 phosphate transporter, low-affinity (NCBI) compare
b2808 gcvA -1.4 -5.5 DNA-binding transcriptional dual regulator (NCBI) compare
b0957 ompA -1.3 -2.7 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4155 yjeA -1.3 -1.9 putative lysyl-tRNA synthetase (VIMSS) compare
b0464 acrR -1.3 -8.5 DNA-binding transcriptional repressor (NCBI) compare
b0729 sucD -1.3 -3.5 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3726 pstA -1.3 -5.7 phosphate transporter subunit (NCBI) compare
b1861 ruvA -1.3 -2.2 Holliday junction DNA helicase motor protein (NCBI) compare
b4685 yrbN -1.3 -2.7 expressed protein (RefSeq) compare
b1863 ruvC -1.3 -2.8 Holliday junction resolvase (NCBI) compare
b0114 aceE -1.3 -2.9 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3741 gidA -1.3 -7.4 glucose-inhibited division protein A (NCBI) compare
b3472 b3472 -1.3 -7.2 orf, hypothetical protein (VIMSS) compare
b3863 polA -1.3 -1.8 DNA polymerase I (NCBI) compare
b3728 pstS -1.3 -4.9 phosphate transporter subunit (NCBI) compare
b3806 cyaA -1.2 -5.8 adenylate cyclase (NCBI) compare
b1084 rne -1.2 -4.9 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4139 aspA -1.2 -7.5 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2820 recB -1.2 -3.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3962 udhA -1.2 -7.4 putative oxidoreductase (VIMSS) compare
b1961 dcm -1.2 -2.4 DNA cytosine methylase (NCBI) compare
b3911 cpxA -1.2 -8.4 two-component sensor protein (NCBI) compare
b3232 yhcM -1.1 -6.8 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b3706 trmE -1.1 -5.5 tRNA modification GTPase (NCBI) compare
b4438 cyaR -1.1 -2.9 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b1286 rnb -1.1 -3.2 exoribonuclease II (NCBI) compare
b3387 dam -1.1 -8.4 DNA adenine methylase (NCBI) compare
b1187 fadR -1.1 -3.3 fatty acid metabolism regulator (NCBI) compare
b2939 yqgB -1.1 -1.9 predicted protein (RefSeq) compare
b2937 speB -1.1 -6.0 agmatinase (NCBI) compare
b2340 sixA -1.0 -3.6 phosphohistidine phosphatase (NCBI) compare
b1400 paaY -1.0 -2.2 predicted hexapeptide repeat acetyltransferase (NCBI) compare
b3107 yhaL -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b3281 aroE -1.0 -8.0 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b4515 ybgT -1.0 -1.8 hypothetical protein (NCBI) compare
b0728 sucC -1.0 -4.7 succinyl-CoA synthetase subunit beta (NCBI) compare
b1175 minD -1.0 -4.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2910 zapA -1.0 -4.1 protein that localizes to the cytokinetic ring (NCBI) compare
b3791 rffA -1.0 -5.6 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4481 rffT -1.0 -5.1 4-alpha-L-fucosyltransferase (NCBI) compare
b0928 aspC -1.0 -5.1 aspartate aminotransferase, PLP-dependent (NCBI) compare
b2512 yfgL -1.0 -4.6 protein assembly complex, lipoprotein component (NCBI) compare
b3424 glpG -0.9 -6.6 predicted intramembrane serine protease (NCBI) compare
b0888 trxB -0.9 -2.8 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b2104 thiM -0.9 -3.0 hydroxyethylthiazole kinase (NCBI) compare
b1693 aroD -0.9 -5.2 3-dehydroquinate dehydratase (NCBI) compare
b0018 mokC -0.9 -1.2 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b3790 rffC -0.9 -4.1 TDP-fucosamine acetyltransferase (RefSeq) compare
b0400 phoR -0.9 -5.1 sensory histidine kinase in two-component regulatory system with PhoB (NCBI) compare
b3210 arcB -0.9 -6.1 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b2564 pdxJ -0.9 -3.7 pyridoxal phosphate biosynthetic protein (NCBI) compare
b4443 gcvB -0.9 -1.4 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b0767 ybhE -0.9 -3.7 6-phosphogluconolactonase (NCBI) compare
b3500 gor -0.9 -1.5 glutathione reductase (NCBI) compare
b0080 fruR -0.9 -4.3 DNA-binding transcriptional dual regulator (NCBI) compare
b0677 nagA -0.9 -4.7 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b4529 ydbJ -0.9 -1.2 hypothetical protein (NCBI) compare
b4651 yibW -0.9 -1.9 no description compare
b1162 ycgE -0.9 -4.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b1591 b1591 -0.8 -1.8 putative oxidoreductase component (VIMSS) compare
b3094 exuR -0.8 -4.1 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b3807 cyaY -0.8 -4.9 frataxin-like protein (NCBI) compare
b4041 plsB -0.8 -1.8 glycerol-3-phosphate acyltransferase (VIMSS) compare
b3405 ompR -0.8 -3.5 osmolarity response regulator (NCBI) compare
b1830 prc -0.8 -4.1 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b0125 hpt -0.8 -3.6 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b2528 iscA -0.8 -1.5 iron-sulfur cluster assembly protein (NCBI) compare
b1448 yncA -0.8 -1.8 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b2436 hemF -0.8 -3.3 coproporphyrinogen III oxidase (NCBI) compare
b1630 rsxD -0.8 -4.4 electron transport complex protein RnfD (NCBI) compare
b3164 pnp -0.8 -2.5 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0051 ksgA -0.8 -3.8 dimethyladenosine transferase (NCBI) compare
b3260 dusB -0.8 -4.1 tRNA-dihydrouridine synthase B (NCBI) compare
b3628 rfaB -0.8 -6.4 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b0015 dnaJ -0.8 -4.7 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b2569 lepA -0.8 -3.1 GTP-binding protein LepA (NCBI) compare
b2288 nuoA -0.8 -2.2 NADH dehydrogenase I chain A (VIMSS) compare
b0399 phoB -0.7 -4.0 DNA-binding response regulator in two-component regulatory system with PhoR (or CreC) (NCBI) compare
b2518 ndk -0.7 -1.7 nucleoside diphosphate kinase (NCBI) compare
b4179 vacB -0.7 -4.7 putative enzyme (VIMSS) compare
b3205 yhbJ -0.7 -2.7 hypothetical protein (NCBI) compare
b3650 spoT -0.7 -3.4 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b1351 racC -0.7 -2.9 Rac prophage; predicted protein (NCBI) compare
b1138 ymfE -0.7 -1.1 e14 prophage; predicted inner membrane protein (NCBI) compare
b1394 paaG -0.7 -1.9 enoyl-CoA hydratase (NCBI) compare
b1263 trpD -0.7 -2.1 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b0226 dinJ -0.7 -2.1 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b3183 obgE -0.7 -1.1 GTPase involved in cell partioning and DNA repair (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For stress ethyl acetate in Escherichia coli BW25113

For stress ethyl acetate across organisms