Experiment set4IT036 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

LB_plus_SM_buffer with FelixO1_phage (wt new) 0.0075 MOI

200 most important genes:

  gene name fitness t score description  
GFF3890 -7.9 -5.3 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF3905 -7.6 -7.4 regulator of length of O-antigen component of lipopolysaccharide chains compare
GFF1396 -7.5 -15.2 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
GFF34 -7.2 -5.0 FIG01280259: hypothetical protein compare
GFF2968 -7.0 -4.8 Stringent starvation protein A compare
GFF3901 -7.0 -4.5 Phosphomannomutase (EC 5.4.2.8) compare
GFF1808 -6.9 -4.8 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
GFF2880 -6.8 -6.7 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF3888 -6.8 -6.6 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF3887 -6.6 -6.5 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF2882 -6.4 -4.4 Lipopolysaccharide biosynthesis protein RffA compare
GFF4798 -5.9 -5.7 Adenylylsulfate kinase (EC 2.7.1.25) compare
GFF3397 -5.8 -14.4 Transcription-repair coupling factor compare
GFF2475 -5.7 -3.9 Ribonuclease III (EC 3.1.26.3) compare
GFF4601 -5.6 -3.9 Phosphoglucomutase (EC 5.4.2.2) compare
GFF2881 -5.3 -3.7 WzxE protein compare
GFF880 -5.0 -16.6 Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) compare
GFF389 -5.0 -4.8 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF3886 -4.8 -8.2 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
GFF2431 -4.5 -4.3 Chaperone protein HscA compare
GFF824 -4.4 -3.0 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF2922 -4.3 -3.5 Transcription elongation factor GreA compare
GFF2434 -4.3 -1.7 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF3054 -4.3 -10.4 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
GFF4839 -3.9 -14.6 BarA sensory histidine kinase (= VarS = GacS) compare
GFF2430 -3.8 -3.0 Ferredoxin, 2Fe-2S compare
GFF3149 -3.7 -11.6 Type I secretion outer membrane protein, TolC precursor compare
GFF3667 -3.7 -3.4 Cytidylate kinase (EC 2.7.4.25) compare
GFF1634 -3.6 -3.4 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF1699 -3.5 -3.3 BarA-associated response regulator UvrY (= GacA = SirA) compare
GFF4355 -3.4 -1.9 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF1311 -3.4 -16.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
GFF4837 -2.9 -13.3 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF1816 -2.8 -5.9 Electron transport complex protein RnfB compare
GFF1815 -2.7 -3.4 Electron transport complex protein RnfA compare
GFF4788 -2.6 -2.7 RNA polymerase sigma factor RpoS compare
GFF597 -2.6 -4.1 DNA-damage-inducible protein J compare
GFF3643 -2.5 -6.5 Electron transport complex protein RnfG compare
GFF4890 -2.5 -11.3 Transport ATP-binding protein CydC compare
GFF1504 -2.4 -6.1 DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13) compare
GFF3644 -2.4 -4.8 Electron transport complex protein RnfD compare
GFF2991 -2.3 -3.4 Tyrosine recombinase XerD compare
GFF1891 -2.2 -4.6 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
GFF4641 -2.2 -4.8 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
GFF4891 -2.2 -10.6 Transport ATP-binding protein CydD compare
GFF2690 -2.1 -2.9 Peptide transport system permease protein SapC compare
GFF4636 -2.1 -7.7 Succinate dehydrogenase hydrophobic membrane anchor protein compare
GFF4192 -2.1 -3.0 DNA-binding protein HU-alpha compare
GFF3566 -2.0 -5.2 major outer membrane lipoprotein compare
GFF2973 -2.0 -6.3 Putative cytochrome d ubiquinol oxidase subunit III (EC 1.10.3.-) (Cytochrome bd-I oxidase subunit III) compare
GFF3642 -2.0 -5.2 Electron transport complex protein RnfE compare
GFF2433 -2.0 -5.5 Iron binding protein IscA for iron-sulfur cluster assembly compare
GFF1737 -2.0 -2.7 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
GFF1933 -2.0 -4.1 DedA protein compare
GFF4350 -2.0 -1.5 hypothetical protein compare
GFF3862 -2.0 -4.0 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF2051 -2.0 -9.5 Predicted transcriptional regulator of pyridoxine metabolism compare
GFF2943 -1.9 -2.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
GFF158 -1.9 -10.3 Fructose repressor FruR, LacI family compare
GFF1884 -1.9 -2.2 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF2889 -1.9 -9.2 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
GFF1885 -1.9 -6.5 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) compare
GFF3874 -1.9 -2.1 Colanic acid biosynthesis acetyltransferase WcaF (EC 2.3.1.-) compare
GFF4160 -1.9 -5.0 UPF0125 protein yfjF compare
GFF1887 -1.9 -8.9 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) compare
GFF4642 -1.8 -1.9 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
GFF2149 -1.8 -5.1 Malate dehydrogenase (EC 1.1.1.37) compare
GFF87 -1.8 -2.0 C4-type zinc finger protein, DksA/TraR family compare
GFF661 -1.8 -8.2 6-phosphogluconolactonase (EC 3.1.1.31) compare
GFF1058 -1.8 -6.9 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) compare
GFF2104 -1.8 -3.5 ATP-dependent RNA helicase SrmB compare
GFF4634 -1.7 -7.6 Citrate synthase (si) (EC 2.3.3.1) compare
GFF1890 -1.7 -10.1 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
GFF1883 -1.7 -7.4 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) compare
GFF4637 -1.7 -9.4 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF4639 -1.6 -2.3 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF1864 -1.5 -1.7 Polymyxin resistance protein PmrM compare
GFF1886 -1.5 -7.4 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
GFF189 -1.5 -6.0 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF386 -1.5 -3.0 Lipopolysaccharide core biosynthesis protein RfaY compare
GFF982 -1.5 -9.5 Putative cytoplasmic protein USSDB7A compare
GFF2906 -1.5 -4.1 Protein yifE compare
GFF1256 -1.5 -3.3 Chromosome (plasmid) partitioning protein ParA compare
GFF1936 -1.5 -8.6 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) compare
GFF633 -1.5 -4.8 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF1076 -1.5 -2.0 Aerobic respiration control protein arcA compare
GFF4638 -1.4 -6.3 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) compare
GFF1889 -1.4 -7.6 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
GFF2907 -1.4 -4.5 HTH-type transcriptional regulator hdfR compare
GFF928 -1.4 -6.3 Endoribonuclease L-PSP compare
GFF4646 -1.4 -6.7 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF4579 -1.4 -8.6 tRNA-i(6)A37 methylthiotransferase compare
GFF1303 -1.4 -1.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF2949 -1.4 -3.8 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
GFF1950 -1.4 -4.4 Chorismate synthase (EC 4.2.3.5) compare
GFF2216 -1.4 -5.6 DNA polymerase I (EC 2.7.7.7) compare
GFF2698 -1.4 -7.8 Exoribonuclease II (EC 3.1.13.1) compare
GFF4600 -1.4 -2.0 SeqA protein, negative modulator of initiation of replication compare
GFF4586 -1.4 -2.3 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) compare
GFF1735 -1.3 -4.2 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
GFF2946 -1.3 -3.4 RNA polymerase sigma-54 factor RpoN compare
GFF4789 -1.3 -5.3 Lipoprotein NlpD compare
GFF1880 -1.3 -8.5 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
GFF4647 -1.3 -5.7 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF2249 -1.2 -1.6 Putative merR family bacterial regulatory protein compare
GFF1882 -1.2 -5.9 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) compare
GFF2160 -1.2 -2.8 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF629 -1.2 -1.8 Shikimate kinase I (EC 2.7.1.71) compare
GFF2173 -1.2 -3.0 Chromosomal replication initiator protein DnaA compare
GFF3664 -1.2 -7.0 Phosphoserine aminotransferase (EC 2.6.1.52) compare
GFF1620 -1.2 -1.5 Copper resistance protein CopC compare
GFF1888 -1.2 -2.6 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
GFF2704 -1.1 -2.0 'Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)' transl_table=11 compare
GFF1930 -1.1 -2.6 DedD protein compare
GFF588 -1.1 -4.9 Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1) compare
GFF1879 -1.1 -7.2 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
GFF4865 -1.1 -4.7 Glycine cleavage system transcriptional activator GcvA compare
GFF1088 -1.1 -1.1 FIG01045785: hypothetical protein compare
GFF3996 -1.1 -6.1 DNA-cytosine methyltransferase (EC 2.1.1.37) compare
GFF1881 -1.1 -6.9 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
GFF3828 -1.1 -1.8 Uncharacterized fimbrial chaperone YehC precursor compare
GFF3772 -1.1 -1.3 1-phosphofructokinase (EC 2.7.1.56) compare
GFF175 -1.1 -1.8 DedA family inner membrane protein YabI compare
GFF355 -1.1 -2.0 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF4635 -1.0 -1.7 Succinate dehydrogenase cytochrome b-556 subunit compare
GFF3712 -1.0 -2.7 Cyclic AMP receptor protein compare
GFF4026 -1.0 -2.7 Flagellar biosynthesis protein FliT compare
GFF2110 -1.0 -2.4 Sigma factor RpoE regulatory protein RseC compare
GFF873 -1.0 -1.3 hypothetical protein compare
GFF2016 -1.0 -8.1 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) compare
GFF2276 -1.0 -1.6 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF728 -1.0 -3.3 Dipeptide transport system, periplasmic component in protein degradation cluster compare
GFF2679 -1.0 -4.3 Transcriptional repressor protein TyrR compare
GFF2303 -1.0 -6.6 Putative uncharacterized protein YiiQ compare
GFF4653 -1.0 -2.2 TolA protein compare
GFF4356 -1.0 -4.0 DNA-binding protein HU-beta compare
GFF2212 -1.0 -3.1 YihE protein, a ser/thr kinase implicated in LPS synthesis and Cpx signalling compare
GFF1095 -0.9 -0.9 Putative membrane protein compare
GFF3230 -0.9 -1.2 Transposase compare
GFF4820 -0.9 -3.0 Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2) compare
GFF626 -0.9 -1.2 Type IV pilus biogenesis protein PilO compare
GFF3665 -0.9 -4.2 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
GFF1920 -0.9 -1.1 hypothetical protein compare
GFF1423 -0.9 -5.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) compare
GFF1750 -0.9 -2.4 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF1934 -0.9 -3.2 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF233 -0.9 -3.8 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
GFF2047 -0.9 -4.4 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF3040 -0.9 -5.1 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
GFF119 -0.9 -0.9 hypothetical protein compare
GFF2989 -0.9 -5.7 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF3133 -0.9 -3.9 Putative cell division protein precursor compare
GFF1366 -0.9 -1.8 putative cytoplasmic protein compare
GFF4596 -0.9 -2.8 Ferric uptake regulation protein FUR compare
GFF4411 -0.9 -2.7 Putative NAD(P)-dependent oxidoreductase EC-YbbO compare
GFF2415 -0.9 -3.3 Nucleoside diphosphate kinase (EC 2.7.4.6) compare
GFF3012 -0.9 -4.4 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
GFF4473 -0.9 -1.7 FIG01046818: hypothetical protein compare
GFF2389 -0.9 -1.5 Trk system potassium uptake protein TrkA compare
GFF716 -0.9 -4.4 L,D-transpeptidase YbiS compare
GFF867 -0.9 -1.7 FIG01048799: hypothetical protein compare
GFF4290 -0.8 -4.6 DNA recombination-dependent growth factor C compare
GFF392 -0.8 -1.4 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF4652 -0.8 -1.8 Tol biopolymer transport system, TolR protein compare
GFF4060 -0.8 -1.1 putative cytoplasmic protein compare
GFF870 -0.8 -5.5 FIG00614015: hypothetical protein compare
GFF3794 -0.8 -4.7 SanA protein compare
GFF2063 -0.8 -1.2 Inner membrane protein YfeZ compare
GFF2469 -0.8 -1.0 Transcriptional regulator, LysR family compare
GFF3342 -0.8 -4.0 Dihydroorotase (EC 3.5.2.3) compare
GFF2583 -0.8 -1.2 FIG00638150: hypothetical protein compare
GFF390 -0.8 -1.6 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
GFF365 -0.8 -2.3 Protein YicC compare
GFF4380 -0.8 -4.2 Membrane fusion protein of RND family multidrug efflux pump compare
GFF3384 -0.8 -4.4 PTS system, glucose-specific IIB component (EC 2.7.1.69) / PTS system, glucose-specific IIC component (EC 2.7.1.69) compare
GFF4353 -0.7 -2.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF2219 -0.7 -5.2 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
GFF3285 -0.7 -2.6 Transcriptional activator of 4-hydroxyphenylacetate 3-monooxygenase operon, XylS/AraC family compare
GFF2719 -0.7 -2.6 Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) compare
GFF829 -0.7 -0.9 Putative inner membrane protein YjeT (clustered with HflC) compare
GFF3022 -0.7 -4.6 D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) compare
GFF1221 -0.7 -0.8 hypothetical protein compare
GFF3877 -0.7 -1.7 GDP-mannose mannosyl hydrolase (EC 3.6.1.-) compare
GFF2003 -0.7 -4.5 Putative luxR family bacterial regulatory protein compare
GFF991 -0.7 -0.7 hypothetical protein compare
GFF1715 -0.7 -1.7 Flavoprotein MioC compare
GFF4379 -0.7 -5.3 RND efflux system, inner membrane transporter CmeB compare
GFF3173 -0.7 -4.2 Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY compare
GFF1433 -0.7 -1.4 Putative inner membrane or exported protein compare
GFF2145 -0.7 -0.8 probable ribonuclease inhibitor YPO3690 compare
GFF4740 -0.7 -3.8 MxiG protein; Pathogenicity 1 island effector protein compare
GFF1641 -0.7 -1.1 hypothetical protein compare
GFF1394 -0.7 -2.4 putative cytoplasmic protein compare
GFF2750 -0.7 -2.7 Thymidine kinase (EC 2.7.1.21) compare
GFF2819 -0.7 -2.8 Ribonuclease D (EC 3.1.26.3) compare
GFF2395 -0.7 -1.4 Similar to C-terminal Zn-finger domain of DNA topoisomerase I compare
GFF4286 -0.7 -2.8 Shikimate kinase III (EC 2.7.1.71) compare
GFF3192 -0.7 -4.4 DedA family inner membrane protein YqjA compare
GFF156 -0.6 -1.1 rRNA small subunit methyltransferase H compare
GFF2994 -0.6 -1.1 YgfY COG2938 compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in phage experiments

For phage FelixO1_phage (wt new) across organisms