Experiment set4IT034 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

LB_plus_SM_buffer with FelixO1_phage (wt new) 0.75 MOI

200 most important genes:

  gene name fitness t score description  
GFF1396 -8.5 -5.9 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
GFF3905 -7.8 -5.4 regulator of length of O-antigen component of lipopolysaccharide chains compare
GFF3886 -7.3 -5.1 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
GFF880 -6.8 -10.5 Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) compare
GFF3054 -6.8 -11.4 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
GFF3901 -6.8 -3.4 Phosphomannomutase (EC 5.4.2.8) compare
GFF2880 -6.8 -4.7 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF2968 -6.8 -4.1 Stringent starvation protein A compare
GFF3887 -6.7 -4.6 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF1808 -6.7 -4.3 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
GFF2922 -6.7 -2.0 Transcription elongation factor GreA compare
GFF3890 -6.5 -4.5 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF4798 -6.1 -4.2 Adenylylsulfate kinase (EC 2.7.1.25) compare
GFF3566 -6.0 -4.0 major outer membrane lipoprotein compare
GFF3397 -5.9 -12.7 Transcription-repair coupling factor compare
GFF2882 -5.8 -4.0 Lipopolysaccharide biosynthesis protein RffA compare
GFF3874 -5.6 -3.6 Colanic acid biosynthesis acetyltransferase WcaF (EC 2.3.1.-) compare
GFF34 -5.5 -3.3 FIG01280259: hypothetical protein compare
GFF2475 -5.4 -2.8 Ribonuclease III (EC 3.1.26.3) compare
GFF4601 -5.4 -3.7 Phosphoglucomutase (EC 5.4.2.2) compare
GFF389 -5.2 -3.1 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF2051 -5.0 -10.5 Predicted transcriptional regulator of pyridoxine metabolism compare
GFF2431 -4.9 -2.7 Chaperone protein HscA compare
GFF2430 -4.8 -2.0 Ferredoxin, 2Fe-2S compare
GFF1415 -4.8 -1.4 UPF0337 protein yjbJ compare
GFF3888 -4.8 -5.2 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF2881 -4.7 -3.3 WzxE protein compare
GFF3533 -4.6 -3.0 FIG00638687: hypothetical protein compare
GFF4839 -4.5 -7.7 BarA sensory histidine kinase (= VarS = GacS) compare
GFF1504 -4.5 -8.2 DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13) compare
GFF1311 -4.4 -17.7 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
GFF1816 -4.3 -7.7 Electron transport complex protein RnfB compare
GFF2906 -4.2 -4.1 Protein yifE compare
GFF3149 -4.2 -10.7 Type I secretion outer membrane protein, TolC precursor compare
GFF4837 -4.1 -11.5 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF824 -4.1 -2.8 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF3643 -4.0 -6.4 Electron transport complex protein RnfG compare
GFF1815 -4.0 -3.0 Electron transport complex protein RnfA compare
GFF1634 -3.8 -3.7 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF3644 -3.8 -4.4 Electron transport complex protein RnfD compare
GFF2698 -3.7 -9.9 Exoribonuclease II (EC 3.1.13.1) compare
GFF1699 -3.7 -2.1 BarA-associated response regulator UvrY (= GacA = SirA) compare
GFF4788 -3.6 -6.5 RNA polymerase sigma factor RpoS compare
GFF3642 -3.5 -5.0 Electron transport complex protein RnfE compare
GFF1303 -3.5 -2.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF1936 -3.4 -12.2 Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) compare
GFF4192 -3.4 -3.4 DNA-binding protein HU-alpha compare
GFF1737 -3.4 -3.1 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
GFF233 -3.3 -5.4 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
GFF189 -3.3 -6.9 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF1933 -3.2 -6.8 DedA protein compare
GFF1256 -3.1 -2.1 Chromosome (plasmid) partitioning protein ParA compare
GFF928 -3.0 -9.7 Endoribonuclease L-PSP compare
GFF2907 -2.9 -6.2 HTH-type transcriptional regulator hdfR compare
GFF2434 -2.8 -1.2 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF2110 -2.7 -3.6 Sigma factor RpoE regulatory protein RseC compare
GFF1950 -2.7 -3.9 Chorismate synthase (EC 4.2.3.5) compare
GFF4789 -2.6 -7.9 Lipoprotein NlpD compare
GFF4160 -2.6 -4.3 UPF0125 protein yfjF compare
GFF4355 -2.5 -1.5 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF3664 -2.5 -8.0 Phosphoserine aminotransferase (EC 2.6.1.52) compare
GFF3236 -2.5 -6.4 Dihydroorotate dehydrogenase (EC 1.3.3.1) compare
GFF175 -2.5 -5.3 DedA family inner membrane protein YabI compare
GFF4111 -2.4 -1.3 Curlin genes transcriptional activator compare
GFF2016 -2.4 -12.5 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8) compare
GFF3342 -2.3 -8.8 Dihydroorotase (EC 3.5.2.3) compare
GFF2433 -2.3 -7.7 Iron binding protein IscA for iron-sulfur cluster assembly compare
GFF2973 -2.3 -7.1 Putative cytochrome d ubiquinol oxidase subunit III (EC 1.10.3.-) (Cytochrome bd-I oxidase subunit III) compare
GFF386 -2.3 -5.4 Lipopolysaccharide core biosynthesis protein RfaY compare
GFF1503 -2.2 -4.9 Lipoprotein nlpI precursor compare
GFF365 -2.2 -3.4 Protein YicC compare
GFF1076 -2.2 -2.0 Aerobic respiration control protein arcA compare
GFF4411 -2.1 -5.4 Putative NAD(P)-dependent oxidoreductase EC-YbbO compare
GFF588 -2.1 -3.6 Thiosulfate sulfurtransferase GlpE (EC 2.8.1.1) compare
GFF3022 -2.1 -8.4 D-erythrose-4-phosphate dehydrogenase (EC 1.2.1.72) compare
GFF2415 -2.1 -3.3 Nucleoside diphosphate kinase (EC 2.7.4.6) compare
GFF1058 -2.0 -8.2 NadR transcriptional regulator / Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) compare
GFF1715 -1.9 -3.4 Flavoprotein MioC compare
GFF2819 -1.9 -6.2 Ribonuclease D (EC 3.1.26.3) compare
GFF597 -1.9 -1.0 DNA-damage-inducible protein J compare
GFF2104 -1.9 -3.2 ATP-dependent RNA helicase SrmB compare
GFF4579 -1.8 -7.7 tRNA-i(6)A37 methylthiotransferase compare
GFF1735 -1.8 -3.8 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
GFF1423 -1.8 -9.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) compare
GFF3794 -1.8 -6.9 SanA protein compare
GFF3040 -1.8 -9.0 Biosynthetic arginine decarboxylase (EC 4.1.1.19) compare
GFF2249 -1.8 -1.8 Putative merR family bacterial regulatory protein compare
GFF2303 -1.7 -7.6 Putative uncharacterized protein YiiQ compare
GFF3862 -1.7 -2.0 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF1830 -1.7 -4.6 Two-component sensor protein RcsD (EC 2.7.3.-) compare
GFF3702 -1.7 -2.3 hypothetical protein compare
GFF716 -1.7 -6.0 L,D-transpeptidase YbiS compare
GFF873 -1.7 -1.2 hypothetical protein compare
GFF366 -1.6 -3.4 Ribonuclease PH (EC 2.7.7.56) compare
GFF1554 -1.6 -2.5 Putative transcriptional regulator compare
GFF3996 -1.6 -7.6 DNA-cytosine methyltransferase (EC 2.1.1.37) compare
GFF2991 -1.6 -2.6 Tyrosine recombinase XerD compare
GFF3012 -1.6 -6.3 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
GFF1674 -1.6 -4.5 Universal stress protein C compare
GFF4286 -1.5 -5.7 Shikimate kinase III (EC 2.7.1.71) compare
GFF633 -1.5 -3.0 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF1223 -1.5 -1.1 CcdB toxin protein compare
GFF4642 -1.5 -1.0 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
GFF3613 -1.5 -7.6 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps compare
GFF75 -1.5 -1.4 Major fimbrial subunit StfA compare
GFF367 -1.5 -7.4 Orotate phosphoribosyltransferase (EC 2.4.2.10) compare
GFF115 -1.5 -4.5 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF4634 -1.4 -4.1 Citrate synthase (si) (EC 2.3.3.1) compare
GFF2679 -1.4 -4.1 Transcriptional repressor protein TyrR compare
GFF4797 -1.4 -2.8 Putative cytochrome oxidase subunit compare
GFF982 -1.4 -8.9 Putative cytoplasmic protein USSDB7A compare
GFF3230 -1.4 -1.1 Transposase compare
GFF2517 -1.4 -1.2 [NiFe] hydrogenase nickel incorporation HybF-like protein compare
GFF3395 -1.3 -1.3 Putative outer membrane protein compare
GFF661 -1.3 -5.7 6-phosphogluconolactonase (EC 3.1.1.31) compare
GFF4290 -1.3 -4.4 DNA recombination-dependent growth factor C compare
GFF1348 -1.3 -1.4 FIG01046723: hypothetical protein compare
GFF4356 -1.3 -2.9 DNA-binding protein HU-beta compare
GFF1168 -1.3 -1.2 IncF plasmid conjugative transfer protein TrbI compare
GFF27 -1.3 -1.7 Copper homeostasis protein CutF precursor / Lipoprotein NlpE involeved in surface adhesion compare
GFF3832 -1.3 -2.6 FIG01045739: hypothetical protein compare
GFF1683 -1.3 -5.4 Tyrosine-specific transport protein compare
GFF728 -1.3 -2.8 Dipeptide transport system, periplasmic component in protein degradation cluster compare
GFF1863 -1.3 -1.1 Polymyxin resistance protein PmrL, sucrose-6 phosphate hydrolase compare
GFF2750 -1.3 -3.4 Thymidine kinase (EC 2.7.1.21) compare
GFF87 -1.3 -1.2 C4-type zinc finger protein, DksA/TraR family compare
GFF2847 -1.3 -4.6 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
GFF4243 -1.3 -0.8 Probable secreted protein compare
GFF3196 -1.3 -1.3 Inner membrane protein YqjE compare
GFF4770 -1.2 -1.4 transposase compare
GFF2537 -1.2 -1.8 hypothetical protein compare
GFF4639 -1.2 -1.5 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF4026 -1.2 -3.0 Flagellar biosynthesis protein FliT compare
GFF1207 -1.2 -3.4 Probable regulatory protein compare
GFF969 -1.2 -1.6 FIG007491: hypothetical protein YeeN compare
GFF2003 -1.2 -6.0 Putative luxR family bacterial regulatory protein compare
GFF3212 -1.2 -0.9 FIG01046763: hypothetical protein compare
GFF2885 -1.2 -4.7 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF4822 -1.2 -2.1 Queuosine biosynthesis QueD, PTPS-I compare
GFF1675 -1.2 -3.3 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15) compare
GFF2738 -1.2 -2.7 hypothetical protein compare
GFF662 -1.2 -7.3 Pectinesterase (EC 3.1.1.11) compare
GFF3515 -1.2 -1.5 FIG00637864: hypothetical protein compare
GFF236 -1.2 -0.8 FIG00545237: hypothetical protein compare
GFF3749 -1.2 -3.1 Nucleoid-associated protein NdpA compare
GFF1206 -1.2 -1.7 Putative GerE-family regulatory protein compare
GFF945 -1.2 -2.1 Aspartate N-acetyltransferase (EC 2.3.1.17) compare
GFF930 -1.2 -4.5 Aspartate carbamoyltransferase (EC 2.1.3.2) compare
GFF3911 -1.2 -5.3 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
GFF2050 -1.2 -3.5 Pyridoxal kinase (EC 2.7.1.35) compare
GFF3041 -1.1 -1.0 hypothetical protein compare
GFF2949 -1.1 -3.0 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
GFF4600 -1.1 -1.6 SeqA protein, negative modulator of initiation of replication compare
GFF2212 -1.1 -3.3 YihE protein, a ser/thr kinase implicated in LPS synthesis and Cpx signalling compare
GFF2704 -1.1 -1.6 'Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)' transl_table=11 compare
GFF3087 -1.1 -4.6 FIG074102: hypothetical protein compare
GFF1801 -1.1 -1.2 hypothetical protein compare
GFF2891 -1.1 -3.9 Thioredoxin compare
GFF816 -1.1 -1.2 Phage tail assembly protein I compare
GFF2755 -1.1 -3.4 UPF0225 protein YchJ compare
GFF2989 -1.1 -5.4 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF4638 -1.1 -2.9 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) compare
GFF1521 -1.1 -2.4 rRNA small subunit methyltransferase I compare
GFF3146 -1.1 -1.9 '3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)' transl_table=11 compare
GFF2497 -1.1 -2.0 3-hydroxypropionate dehydrogenase (EC 1.1.1.298) compare
GFF4491 -1.1 -3.9 Enterobactin esterase compare
GFF4641 -1.1 -2.4 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
GFF158 -1.1 -3.7 Fructose repressor FruR, LacI family compare
GFF1632 -1.1 -3.4 Phosphogluconate repressor HexR, RpiR family compare
GFF1033 -1.1 -2.1 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
GFF3322 -1.1 -1.0 Major curlin subunit precursor CsgA compare
GFF1662 -1.1 -2.3 Chemotaxis response - phosphatase CheZ compare
GFF4637 -1.1 -6.4 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF269 -1.1 -2.6 NAD(P)H-flavin reductase (EC 1.5.1.29) (EC 1.16.1.3) compare
GFF1032 -1.0 -0.8 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF1512 -1.0 -4.5 FIG002208: Acetyltransferase (EC 2.3.1.-) compare
GFF4162 -1.0 -2.4 DNA repair protein RecN compare
GFF3048 -1.0 -2.2 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
GFF2887 -1.0 -6.5 UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14) compare
GFF4060 -1.0 -0.9 putative cytoplasmic protein compare
GFF4380 -1.0 -3.7 Membrane fusion protein of RND family multidrug efflux pump compare
GFF2311 -1.0 -0.9 Ribonuclease E inhibitor RraA compare
GFF3460 -1.0 -1.1 Transglycosylase associated protein compare
GFF2202 -1.0 -2.3 hypothetical protein compare
GFF2022 -1.0 -2.2 hypothetical protein compare
GFF4636 -1.0 -3.0 Succinate dehydrogenase hydrophobic membrane anchor protein compare
GFF3558 -1.0 -1.7 Iron binding protein SufA for iron-sulfur cluster assembly compare
GFF4103 -1.0 -5.6 probable exported protein STY0357 compare
GFF4379 -1.0 -6.3 RND efflux system, inner membrane transporter CmeB compare
GFF1864 -1.0 -0.9 Polymyxin resistance protein PmrM compare
GFF4865 -1.0 -3.4 Glycine cleavage system transcriptional activator GcvA compare
GFF4847 -1.0 -4.5 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
GFF296 -1.0 -4.4 Multidrug resistance protein D compare
GFF89 -1.0 -3.2 Poly(A) polymerase (EC 2.7.7.19) compare
GFF1572 -1.0 -2.9 Transcriptional regulator, ArsR family compare
GFF2889 -1.0 -6.5 Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-) compare
GFF2173 -1.0 -3.2 Chromosomal replication initiator protein DnaA compare
GFF842 -1.0 -2.4 Putative uncharacterized protein YjfN compare
GFF2967 -1.0 -1.4 ClpXP protease specificity-enhancing factor / Stringent starvation protein B compare
GFF905 -0.9 -1.1 Soluble cytochrome b562 compare


Specific Phenotypes

For 11 genes in this experiment

For phage FelixO1_phage (wt new) in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

For phage FelixO1_phage (wt new) across organisms