Experiment set4IT027 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

LB_plus_SM_buffer with 6C2_phage 0.25 MOI

200 most important genes:

  gene name fitness t score description  
GFF2213 -7.1 -6.9 Periplasmic thiol:disulfide interchange protein DsbA compare
GFF2808 -6.1 -10.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
GFF4601 -5.6 -6.6 Phosphoglucomutase (EC 5.4.2.2) compare
GFF2216 -5.6 -5.4 DNA polymerase I (EC 2.7.7.7) compare
GFF20 -4.8 -6.5 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF2475 -4.6 -3.1 Ribonuclease III (EC 3.1.26.3) compare
GFF1634 -4.3 -3.0 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF4355 -4.3 -1.7 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF4891 -4.2 -16.0 Transport ATP-binding protein CydD compare
GFF3901 -4.1 -3.9 Phosphomannomutase (EC 5.4.2.8) compare
GFF4646 -4.0 -13.8 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF4890 -3.7 -10.0 Transport ATP-binding protein CydC compare
GFF824 -3.7 -4.3 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF2968 -3.6 -6.3 Stringent starvation protein A compare
GFF2047 -3.6 -9.6 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF3862 -3.6 -5.5 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF2991 -3.6 -3.5 Tyrosine recombinase XerD compare
GFF4652 -3.5 -5.1 Tol biopolymer transport system, TolR protein compare
GFF4647 -3.4 -10.3 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF701 -3.0 -1.9 Hypothetical Zinc-finger containing protein compare
GFF4654 -2.9 -8.0 tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins compare
GFF4653 -2.8 -3.5 TolA protein compare
GFF2881 -2.7 -11.7 WzxE protein compare
GFF2946 -2.7 -5.1 RNA polymerase sigma-54 factor RpoN compare
GFF1750 -2.7 -3.7 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF629 -2.6 -2.1 Shikimate kinase I (EC 2.7.1.71) compare
GFF1716 -2.6 -7.4 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF3887 -2.6 -6.8 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF2943 -2.6 -1.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
GFF1934 -2.5 -4.7 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF4655 -2.5 -2.9 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF587 -2.5 -4.8 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
GFF3667 -2.4 -1.9 Cytidylate kinase (EC 2.7.4.25) compare
GFF2001 -2.4 -1.6 Quaternary ammonium compound-resistance protein SugE compare
GFF652 -2.4 -14.0 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) / UDP-glucose 4-epimerase (EC 5.1.3.2) compare
GFF4605 -2.4 -1.1 hypothetical protein compare
GFF158 -2.4 -10.4 Fructose repressor FruR, LacI family compare
GFF4192 -2.4 -3.9 DNA-binding protein HU-alpha compare
GFF825 -2.3 -1.8 RNA-binding protein Hfq compare
GFF1076 -2.3 -3.0 Aerobic respiration control protein arcA compare
GFF1303 -2.3 -1.9 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF2436 -2.3 -3.6 Iron-sulfur cluster regulator IscR compare
GFF355 -2.3 -3.0 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF2061 -2.2 -8.4 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
GFF392 -2.2 -2.7 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF3888 -2.2 -7.1 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF3490 -2.2 -9.1 Exodeoxyribonuclease III (EC 3.1.11.2) compare
GFF1032 -2.1 -1.1 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF1884 -2.0 -1.5 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF3890 -2.0 -6.0 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF4634 -2.0 -7.1 Citrate synthase (si) (EC 2.3.3.1) compare
GFF389 -1.9 -5.7 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF2392 -1.9 -2.2 Peptide deformylase (EC 3.5.1.88) compare
GFF633 -1.9 -4.9 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF2434 -1.9 -1.2 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF1205 -1.9 -2.9 hypothetical protein compare
GFF707 -1.9 -5.0 Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1) compare
GFF192 -1.9 -7.7 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF2537 -1.9 -2.0 hypothetical protein compare
GFF4639 -1.9 -2.3 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF242 -1.8 -3.6 Magnesium and cobalt transport protein CorA compare
GFF1440 -1.8 -11.5 FIG00638940: hypothetical protein compare
GFF55 -1.8 -8.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF4798 -1.8 -4.1 Adenylylsulfate kinase (EC 2.7.1.25) compare
GFF2882 -1.7 -9.3 Lipopolysaccharide biosynthesis protein RffA compare
GFF1808 -1.7 -4.3 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
GFF635 -1.7 -5.2 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF4175 -1.7 -2.6 Uncharacterized protein YfiR precursor compare
GFF1885 -1.7 -7.9 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) compare
GFF1890 -1.7 -10.1 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
GFF1090 -1.6 -3.4 Chaperone protein DnaJ compare
GFF4162 -1.6 -4.2 DNA repair protein RecN compare
GFF2104 -1.6 -2.6 ATP-dependent RNA helicase SrmB compare
GFF2409 -1.6 -5.5 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
GFF87 -1.6 -1.7 C4-type zinc finger protein, DksA/TraR family compare
GFF2922 -1.6 -2.4 Transcription elongation factor GreA compare
GFF4600 -1.6 -2.8 SeqA protein, negative modulator of initiation of replication compare
GFF1256 -1.6 -3.3 Chromosome (plasmid) partitioning protein ParA compare
GFF3712 -1.6 -3.6 Cyclic AMP receptor protein compare
GFF4837 -1.6 -7.2 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF1882 -1.6 -5.7 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) compare
GFF384 -1.6 -2.4 UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,3-glucosyltransferase WaaO (EC 2.4.1.-) compare
GFF1886 -1.6 -7.7 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
GFF2389 -1.6 -2.4 Trk system potassium uptake protein TrkA compare
GFF4288 -1.5 -7.2 AroM protein compare
GFF4353 -1.5 -4.4 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF1348 -1.5 -1.7 FIG01046723: hypothetical protein compare
GFF1879 -1.5 -9.4 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
GFF3772 -1.5 -1.6 1-phosphofructokinase (EC 2.7.1.56) compare
GFF1889 -1.5 -9.2 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
GFF2311 -1.5 -1.3 Ribonuclease E inhibitor RraA compare
GFF1887 -1.5 -6.5 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) compare
GFF3324 -1.5 -1.1 putative periplasmic protein compare
GFF4354 -1.5 -3.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF1881 -1.5 -8.0 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
GFF4027 -1.4 -1.5 Flagellar biosynthesis protein FliS compare
GFF1415 -1.4 -0.9 UPF0337 protein yjbJ compare
GFF1312 -1.4 -2.2 'Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-)' transl_table=11 compare
GFF34 -1.4 -1.7 FIG01280259: hypothetical protein compare
GFF4182 -1.4 -5.8 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) compare
GFF3528 -1.4 -2.2 Integration host factor alpha subunit compare
GFF773 -1.4 -1.5 probable lipoprotein compare
GFF4408 -1.4 -4.0 YbbL ABC transporter ATP-binding protein compare
GFF1883 -1.4 -7.1 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) compare
GFF632 -1.4 -5.8 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF1880 -1.4 -8.0 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
GFF2220 -1.3 -6.9 Nitrogen regulation protein NR(I) compare
GFF4390 -1.3 -4.9 Recombination protein RecR compare
GFF2173 -1.3 -3.8 Chromosomal replication initiator protein DnaA compare
GFF2430 -1.3 -1.4 Ferredoxin, 2Fe-2S compare
GFF3595 -1.3 -2.5 Secretion system effector SseG compare
GFF2119 -1.3 -1.4 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
GFF3886 -1.3 -4.1 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
GFF4774 -1.3 -1.2 FIG074102: hypothetical protein compare
GFF2539 -1.2 -1.8 putative phage-related secreted protein compare
GFF3518 -1.2 -1.5 putative outer membrane protein compare
GFF236 -1.2 -0.7 FIG00545237: hypothetical protein compare
GFF4635 -1.2 -2.5 Succinate dehydrogenase cytochrome b-556 subunit compare
GFF2431 -1.2 -2.5 Chaperone protein HscA compare
GFF267 -1.2 -6.4 Transcriptional activator RfaH compare
GFF2954 -1.2 -7.4 Aerobic respiration control sensor protein arcB (EC 2.7.3.-) compare
GFF520 -1.2 -2.0 Universal stress protein A compare
GFF883 -1.2 -6.9 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
GFF2690 -1.2 -1.0 Peptide transport system permease protein SapC compare
GFF1921 -1.2 -1.8 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) compare
GFF2517 -1.2 -1.2 [NiFe] hydrogenase nickel incorporation HybF-like protein compare
GFF4537 -1.2 -2.0 CrcB protein compare
GFF122 -1.2 -6.8 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF1785 -1.1 -6.3 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon compare
GFF1891 -1.1 -2.0 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
GFF3558 -1.1 -1.8 Iron binding protein SufA for iron-sulfur cluster assembly compare
GFF2276 -1.1 -1.0 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF188 -1.1 -4.6 Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) compare
GFF2051 -1.1 -6.3 Predicted transcriptional regulator of pyridoxine metabolism compare
GFF3905 -1.1 -5.2 regulator of length of O-antigen component of lipopolysaccharide chains compare
GFF499 -1.1 -6.0 GGDEF/EAL domain protein YhjH compare
GFF387 -1.1 -2.7 Lipopolysaccharide core biosynthesis protein RfaZ compare
GFF241 -1.1 -4.9 ATP-dependent DNA helicase UvrD/PcrA compare
GFF831 -1.1 -3.5 Nitrite-sensitive transcriptional repressor NsrR compare
GFF230 -1.1 -5.9 Adenylate cyclase (EC 4.6.1.1) compare
GFF115 -1.1 -3.2 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF3397 -1.1 -6.7 Transcription-repair coupling factor compare
GFF3545 -1.1 -1.3 Transcriptional regulator, AraC family compare
GFF2989 -1.1 -3.8 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF4790 -1.1 -1.2 FIG01047833: hypothetical protein compare
GFF3777 -1.1 -1.9 LysR family transcriptional regulator YeiE compare
GFF3747 -1.1 -5.5 FIG001881: hydrolase of alkaline phosphatase superfamily compare
GFF2863 -1.1 -1.1 FIG074102: hypothetical protein compare
GFF3362 -1.0 -2.5 Flagellar protein FlgJ [peptidoglycan hydrolase] (EC 3.2.1.-) compare
GFF3644 -1.0 -2.2 Electron transport complex protein RnfD compare
GFF4239 -1.0 -2.2 Putative inner membrane protein compare
GFF4596 -1.0 -2.4 Ferric uptake regulation protein FUR compare
GFF4356 -1.0 -2.3 DNA-binding protein HU-beta compare
GFF1497 -1.0 -2.0 Transcription termination protein NusA compare
GFF2149 -1.0 -4.3 Malate dehydrogenase (EC 1.1.1.37) compare
GFF4160 -1.0 -2.8 UPF0125 protein yfjF compare
GFF2221 -1.0 -4.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
GFF121 -1.0 -2.9 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF3460 -1.0 -1.8 Transglycosylase associated protein compare
GFF3230 -1.0 -0.9 Transposase compare
GFF1660 -1.0 -3.6 Flagellar biosynthesis protein FlhA compare
GFF4835 -1.0 -1.5 ParE toxin protein compare
GFF2692 -1.0 -3.7 Peptide transport system ATP-binding protein SapF compare
GFF1933 -1.0 -2.5 DedA protein compare
GFF2825 -1.0 -1.8 FIG00638134: hypothetical protein compare
GFF110 -0.9 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF238 -0.9 -1.5 Protein of unknown function DUF484 compare
GFF873 -0.9 -0.8 hypothetical protein compare
GFF4637 -0.9 -6.3 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF1411 -0.9 -3.9 Diacylglycerol kinase (EC 2.7.1.107) compare
GFF2719 -0.9 -3.0 Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) compare
GFF2219 -0.9 -5.9 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
GFF1013 -0.9 -4.0 PTS system, mannose-specific IIB component (EC 2.7.1.69) compare
GFF1559 -0.9 -1.6 hypothetical protein compare
GFF391 -0.9 -1.6 ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) compare
GFF4016 -0.9 -1.4 Flagellar assembly protein FliH compare
GFF2223 -0.9 -3.8 GTP-binding protein TypA/BipA compare
GFF4892 -0.9 -1.9 Thioredoxin reductase (EC 1.8.1.9) compare
GFF368 -0.9 -2.3 Transcriptional regulator SlmA, TetR family compare
GFF1888 -0.9 -1.9 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
GFF1662 -0.9 -3.0 Chemotaxis response - phosphatase CheZ compare
GFF4852 -0.9 -3.6 Serine transporter compare
GFF4615 -0.9 -1.1 FIG137478: Hypothetical protein YbgI compare
GFF2880 -0.9 -4.1 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF183 -0.9 -5.1 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
GFF4409 -0.9 -6.0 YbbM seven transmembrane helix protein compare
GFF3450 -0.9 -2.9 Transcriptional regulator, MerR family compare
GFF622 -0.9 -2.3 ADP compounds hydrolase NudE (EC 3.6.1.-) compare
GFF1504 -0.9 -3.1 DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13) compare
GFF2167 -0.9 -3.9 Polyphosphate kinase (EC 2.7.4.1) compare
GFF3054 -0.9 -6.0 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
GFF3447 -0.9 -2.3 Candidate zinc-binding lipoprotein ZinT compare
GFF1353 -0.9 -1.3 hypothetical protein compare
GFF3298 -0.9 -1.6 FIG01049236: hypothetical protein compare
GFF4387 -0.9 -1.6 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
GFF27 -0.9 -1.2 Copper homeostasis protein CutF precursor / Lipoprotein NlpE involeved in surface adhesion compare
GFF1801 -0.9 -1.0 hypothetical protein compare
GFF3063 -0.9 -3.2 FIG002060: uncharacterized protein YggL compare
GFF1396 -0.9 -6.5 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
GFF4641 -0.9 -1.5 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare


Specific Phenotypes

For 1 genes in this experiment

For phage 6C2_phage in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

For phage 6C2_phage across organisms