Experiment set4IT020 for Escherichia coli BW25113

Compare to:

LB with 3-methyl-2-butenol 0.31 vol%

200 most important genes:

  gene name fitness t score description  
b2620 smpB -3.5 -4.7 SsrA-binding protein (NCBI) compare
b2699 recA -3.5 -3.3 recombinase A (NCBI) compare
b2330 yfcB -3.3 -4.3 putative adenine-specific methylase (VIMSS) compare
b0630 lipB -3.2 -3.1 protein of lipoate biosynthesis (VIMSS) compare
b2820 recB -2.8 -3.7 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1175 minD -2.6 -7.9 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3463 ftsE -2.5 -6.5 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3493 pitA -2.3 -12.1 phosphate transporter, low-affinity (NCBI) compare
b4375 prfC -2.3 -9.9 peptide chain release factor 3 (NCBI) compare
b2935 tktA -2.3 -5.1 transketolase 1, thiamin-binding (NCBI) compare
b0118 acnB -2.2 -5.2 aconitate hydratase (NCBI) compare
b3162 deaD -2.2 -8.0 inducible ATP-independent RNA helicase (VIMSS) compare
b3462 ftsX -2.0 -8.1 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3290 trkA -1.9 -4.9 potassium transporter peripheral membrane component (NCBI) compare
b3725 pstB -1.9 -4.0 phosphate transporter subunit (NCBI) compare
b0014 dnaK -1.8 -3.0 molecular chaperone DnaK (NCBI) compare
b3839 tatC -1.8 -9.8 TatABCE protein translocation system subunit (NCBI) compare
b1176 minC -1.7 -5.5 septum formation inhibitor (NCBI) compare
b0222 lpcA -1.7 -3.9 phosphoheptose isomerase (NCBI) compare
b3261 fis -1.6 -3.9 DNA-binding protein Fis (NCBI) compare
b3500 gor -1.6 -2.3 glutathione reductase (NCBI) compare
b1236 galU -1.6 -6.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3414 gntY -1.5 -6.6 predicted gluconate transport associated protein (NCBI) compare
b0890 ftsK -1.5 -8.3 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b4585 sroB -1.5 -1.9 Novel sRNA, function unknown (RefSeq) compare
b4155 yjeA -1.5 -2.1 putative lysyl-tRNA synthetase (VIMSS) compare
b1712 ihfA -1.4 -3.8 integration host factor subunit alpha (NCBI) compare
b0726 sucA -1.4 -4.2 alpha-ketoglutarate decarboxylase (NCBI) compare
b4239 treC -1.4 -6.4 trehalose-6-P hydrolase (NCBI) compare
b3811 xerC -1.4 -3.8 site-specific tyrosine recombinase XerC (NCBI) compare
b0949 uup -1.4 -6.8 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3619 rfaD -1.4 -4.6 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3621 rfaC -1.4 -5.9 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3871 bipA -1.4 -9.0 GTP-binding protein (NCBI) compare
b3609 secB -1.3 -2.9 export protein SecB (NCBI) compare
b2894 xerD -1.3 -2.2 site-specific tyrosine recombinase XerD (NCBI) compare
b4505 insX -1.3 -2.5 predicted IS protein (RefSeq) compare
b1144 ymfJ -1.3 -2.8 orf, hypothetical protein (VIMSS) compare
b2822 recC -1.3 -5.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4172 hfq -1.2 -2.4 RNA-binding protein Hfq (NCBI) compare
b2614 grpE -1.2 -2.8 heat shock protein (NCBI) compare
b2297 pta -1.2 -1.9 phosphate acetyltransferase (NCBI) compare
b0053 surA -1.2 -5.3 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1861 ruvA -1.2 -1.9 Holliday junction DNA helicase motor protein (NCBI) compare
b3386 rpe -1.2 -1.8 ribulose-phosphate 3-epimerase (NCBI) compare
b3838 tatB -1.2 -5.9 sec-independent translocase (NCBI) compare
b4685 yrbN -1.2 -2.6 expressed protein (RefSeq) compare
b1293 sapB -1.1 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3761 trpT -1.1 -2.0 tRNA-Trp (NCBI) compare
b3979 thrT -1.1 -1.4 tRNA-Thr (NCBI) compare
b4202 rpsR -1.1 -2.0 30S ribosomal protein S18 (NCBI) compare
b1724 ydiZ -1.1 -2.4 hypothetical protein (NCBI) compare
b3052 rfaE -1.1 -4.9 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3237 argR -1.1 -4.0 arginine repressor (NCBI) compare
b0439 lon -1.1 -4.8 DNA-binding ATP-dependent protease La (NCBI) compare
b0357 yaiN -1.1 -2.3 putative alpha helix chain (VIMSS) compare
b3198 kdsC -1.0 -3.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b0200 gmhB -1.0 -1.9 hypothetical protein (NCBI) compare
b2784 relA -1.0 -6.5 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1109 ndh -1.0 -4.1 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b1863 ruvC -1.0 -3.4 Holliday junction resolvase (NCBI) compare
b3390 aroK -1.0 -2.2 shikimate kinase I (NCBI) compare
b4546 ypeB -1.0 -1.6 hypothetical protein (NCBI) compare
b3961 oxyR -1.0 -6.6 DNA-binding transcriptional dual regulator (NCBI) compare
b4177 purA -1.0 -3.5 adenylosuccinate synthetase (NCBI) compare
b0738 tolR -1.0 -3.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3426 glpD -1.0 -5.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2479 gcvR -0.9 -3.8 transcriptional regulation of gcv operon (VIMSS) compare
b1890 motA -0.9 -2.4 flagellar motor protein MotA (NCBI) compare
b1984 asnW -0.9 -1.3 tRNA-Asn (NCBI) compare
b1292 sapC -0.9 -2.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3706 trmE -0.9 -5.3 tRNA modification GTPase (NCBI) compare
b3620 rfaF -0.9 -4.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0450 glnK -0.9 -2.4 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b2567 rnc -0.9 -1.7 ribonuclease III (NCBI) compare
b2688 gshA -0.9 -5.1 glutamate--cysteine ligase (NCBI) compare
b3613 yibP -0.9 -4.7 putative membrane protein (VIMSS) compare
b2277 nuoM -0.9 -4.8 NADH dehydrogenase subunit M (NCBI) compare
b2528 iscA -0.9 -1.9 iron-sulfur cluster assembly protein (NCBI) compare
b0226 dinJ -0.9 -2.4 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b4582 yoeA -0.9 -2.3 no description compare
b0051 ksgA -0.9 -4.3 dimethyladenosine transferase (NCBI) compare
b3807 cyaY -0.8 -4.2 frataxin-like protein (NCBI) compare
b0683 fur -0.8 -1.1 ferric uptake regulator (NCBI) compare
b3935 priA -0.8 -0.8 primosome assembly protein PriA (NCBI) compare
b1095 fabF -0.8 -4.5 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3649 rpoZ -0.8 -2.8 DNA-directed RNA polymerase subunit omega (NCBI) compare
b2288 nuoA -0.8 -2.4 NADH dehydrogenase I chain A (VIMSS) compare
b0739 tolA -0.8 -3.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3728 pstS -0.8 -3.6 phosphate transporter subunit (NCBI) compare
b3631 rfaG -0.8 -7.0 glucosyltransferase I (NCBI) compare
b3806 cyaA -0.8 -3.7 adenylate cyclase (NCBI) compare
b1151 ymfO -0.8 -2.4 e14 prophage; conserved protein (RefSeq) compare
b1679 sufE -0.8 -3.0 cysteine desufuration protein SufE (NCBI) compare
b2948 yqgE -0.8 -2.3 orf, hypothetical protein (VIMSS) compare
b0114 aceE -0.8 -2.0 pyruvate dehydrogenase subunit E1 (NCBI) compare
b1291 sapD -0.8 -1.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0740 tolB -0.8 -3.2 translocation protein TolB precursor (NCBI) compare
b1261 trpB -0.7 -1.9 tryptophan synthase subunit beta (NCBI) compare
b3870 glnA -0.7 -2.3 glutamine synthetase (NCBI) compare
b3630 rfaP -0.7 -5.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b2564 pdxJ -0.7 -2.6 pyridoxal phosphate biosynthetic protein (NCBI) compare
b3229 sspA -0.7 -2.7 stringent starvation protein A (NCBI) compare
b2576 srmB -0.7 -2.8 ATP-dependent RNA helicase (NCBI) compare
b4458 oxyS -0.7 -0.7 global regulatory RNA (NCBI) compare
b2278 nuoL -0.7 -4.9 NADH dehydrogenase subunit L (NCBI) compare
b3726 pstA -0.7 -4.0 phosphate transporter subunit (NCBI) compare
b3341 rpsG -0.7 -1.1 30S ribosomal protein S7 (NCBI) compare
b1263 trpD -0.7 -2.1 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b2282 nuoH -0.7 -2.3 NADH dehydrogenase subunit H (NCBI) compare
b3148 yraN -0.7 -2.1 hypothetical protein (NCBI) compare
b3169 nusA -0.7 -2.1 transcription elongation factor NusA (NCBI) compare
b4551 yheV -0.7 -1.4 hypothetical protein (NCBI) compare
b3026 qseC -0.7 -3.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1545 pinQ -0.7 -1.3 Qin prophage; predicted site-specific recombinase (NCBI) compare
b3842 rfaH -0.7 -3.2 transcriptional activator RfaH (NCBI) compare
b2947 gshB -0.7 -3.1 glutathione synthetase (NCBI) compare
b3933 ftsN -0.7 -5.2 essential cell division protein (NCBI) compare
b3778 rep -0.7 -4.7 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2276 nuoN -0.7 -3.6 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b4050 yjbO -0.7 -2.3 orf, hypothetical protein (VIMSS) compare
b1954 dsrA -0.7 -1.9 regulatory antisense RNA (NCBI) compare
b1658 purR -0.7 -3.5 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b2512 yfgL -0.7 -2.8 protein assembly complex, lipoprotein component (NCBI) compare
b2286 nuoC -0.7 -3.5 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b2283 nuoG -0.6 -3.6 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b0953 rmf -0.6 -1.3 ribosome modulation factor (NCBI) compare
b3164 pnp -0.6 -1.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2114 metG -0.6 -0.8 methionyl-tRNA synthetase (NCBI) compare
b0676 nagC -0.6 -4.3 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b1426 ydcH -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b0082 mraW -0.6 -2.5 S-adenosyl-methyltransferase (NCBI) compare
b0145 dksA -0.6 -1.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4515 ybgT -0.6 -1.3 hypothetical protein (NCBI) compare
b0183 rnhB -0.6 -1.7 ribonuclease HII (NCBI) compare
b1286 rnb -0.6 -2.1 exoribonuclease II (NCBI) compare
b3348 slyX -0.6 -2.4 hypothetical protein (NCBI) compare
b1842 holE -0.6 -1.4 DNA polymerase III, theta subunit (NCBI) compare
b2635 ypjK -0.6 -2.0 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1685 ydiH -0.6 -0.9 predicted protein (RefSeq) compare
b2436 hemF -0.6 -2.5 coproporphyrinogen III oxidase (NCBI) compare
b0149 mrcB -0.6 -4.9 penicillin-binding protein 1b (NCBI) compare
b0741 pal -0.6 -2.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b4704 arrS -0.6 -1.1 Antisense sRNA ArrS, function unknown (NCBI) compare
b2897 ygfY -0.6 -2.2 hypothetical protein (NCBI) compare
b2754 ygbF -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b0677 nagA -0.6 -3.4 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b2104 thiM -0.6 -2.4 hydroxyethylthiazole kinase (NCBI) compare
b0428 cyoE -0.6 -3.5 protoheme IX farnesyltransferase (NCBI) compare
b3107 yhaL -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b0736 ybgC -0.6 -1.6 predicted acyl-CoA thioesterase (NCBI) compare
b1346 ydaQ -0.6 -1.8 orf, hypothetical protein (VIMSS) compare
b1855 lpxM -0.6 -2.5 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b3741 gidA -0.6 -4.0 glucose-inhibited division protein A (NCBI) compare
b4208 cycA -0.6 -4.1 D-alanine/D-serine/glycine transporter (NCBI) compare
b2392 mntH -0.6 -3.3 manganese transport protein MntH (NCBI) compare
b1676 pykF -0.6 -2.3 pyruvate kinase (NCBI) compare
b3652 recG -0.6 -4.3 ATP-dependent DNA helicase (NCBI) compare
b3781 trxA -0.6 -2.1 thioredoxin 1 (VIMSS) compare
b3916 pfkA -0.6 -2.2 6-phosphofructokinase (NCBI) compare
b1266 yciV -0.6 -1.5 hypothetical protein (NCBI) compare
b1848 yebG -0.6 -1.0 conserved protein regulated by LexA (NCBI) compare
b3035 tolC -0.6 -4.0 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3002 yqhA -0.6 -1.1 hypothetical protein (NCBI) compare
b1217 chaB -0.6 -1.2 cation transport regulator (NCBI) compare
b4435 isrC -0.6 -1.1 unknown RNA (NCBI) compare
b3465 yhhF -0.6 -2.7 predicted methyltransferase (NCBI) compare
b0623 cspE -0.6 -1.5 cold shock protein E (NCBI) compare
b1083 flgL -0.6 -2.7 flagellar hook-associated protein L (NCBI) compare
b0542 renD -0.6 -1.0 orf, hypothetical protein (VIMSS) compare
b4178 yjeB -0.6 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0767 ybhE -0.6 -2.1 6-phosphogluconolactonase (NCBI) compare
b1105 ycfM -0.6 -2.1 predicted outer membrane lipoprotein (NCBI) compare
b2390 ypeC -0.6 -2.2 hypothetical protein (NCBI) compare
b2707 srlR -0.6 -3.4 DNA-bindng transcriptional repressor (NCBI) compare
b2340 sixA -0.5 -2.0 phosphohistidine phosphatase (NCBI) compare
b0660 ybeZ -0.5 -2.6 predicted protein with nucleoside triphosphate hydrolase domain (RefSeq) compare
b1187 fadR -0.5 -2.9 fatty acid metabolism regulator (NCBI) compare
b2892 recJ -0.5 -3.7 ssDNA exonuclease, 5' --> 3'-specific (NCBI) compare
b0849 grxA -0.5 -1.5 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) (NCBI) compare
b4042 dgkA -0.5 -2.0 diacylglycerol kinase (NCBI) compare
b3727 pstC -0.5 -2.9 phosphate transporter subunit (NCBI) compare
b3021 ygiT -0.5 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b1383 ydbL -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b1476 fdnI -0.5 -1.1 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b3884 yihW -0.5 -3.2 putative DEOR-type transcriptional regulator (VIMSS) compare
b1874 cutC -0.5 -1.6 copper homeostasis protein (NCBI) compare
b4234 yjgA -0.5 -2.4 hypothetical protein (NCBI) compare
b4146 yjeK -0.5 -2.3 predicted lysine aminomutase (NCBI) compare
b0167 glnD -0.5 -2.3 PII uridylyl-transferase (NCBI) compare
b1550 b1550 -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b1811 yoaH -0.5 -1.3 hypothetical protein (NCBI) compare
b1080 flgI -0.5 -3.1 homolog of Salmonella P-ring of flagella basal body (VIMSS) compare
b1860 ruvB -0.5 -0.9 Holliday junction DNA helicase B (NCBI) compare
b2742 nlpD -0.5 -3.3 predicted outer membrane lipoprotein (NCBI) compare
b1394 paaG -0.5 -1.3 enoyl-CoA hydratase (NCBI) compare
b4578 insP -0.5 -1.4 no description compare
b0427 yajR -0.5 -3.9 putative transport protein (VIMSS) compare
b1177 ycgJ -0.5 -2.7 hypothetical protein (NCBI) compare
b2287 nuoB -0.5 -2.0 NADH dehydrogenase subunit B (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in stress experiments

For stress 3-methyl-2-butenol across organisms