Experiment set4IT012 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

LB_plus_SM_buffer

200 most important genes:

  gene name fitness t score description  
GFF2216 -6.0 -4.1 DNA polymerase I (EC 2.7.7.7) compare
GFF1076 -5.8 -5.5 Aerobic respiration control protein arcA compare
GFF3901 -5.2 -4.1 Phosphomannomutase (EC 5.4.2.8) compare
GFF2475 -5.1 -3.5 Ribonuclease III (EC 3.1.26.3) compare
GFF4890 -5.1 -12.7 Transport ATP-binding protein CydC compare
GFF4891 -4.5 -13.5 Transport ATP-binding protein CydD compare
GFF3490 -4.5 -11.6 Exodeoxyribonuclease III (EC 3.1.11.2) compare
GFF3862 -4.2 -6.9 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF192 -4.2 -11.4 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF3887 -4.2 -12.2 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) compare
GFF4646 -3.8 -13.2 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF4647 -3.7 -8.1 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF2968 -3.4 -6.6 Stringent starvation protein A compare
GFF1634 -3.3 -3.9 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF633 -3.3 -7.0 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF3890 -3.1 -3.3 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF3888 -2.9 -5.3 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF2061 -2.7 -9.7 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
GFF825 -2.7 -3.9 RNA-binding protein Hfq compare
GFF707 -2.7 -6.8 Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1) compare
GFF4162 -2.6 -5.8 DNA repair protein RecN compare
GFF1303 -2.4 -2.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF2991 -2.3 -3.5 Tyrosine recombinase XerD compare
GFF4837 -2.3 -10.2 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF1750 -2.3 -3.8 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF4634 -2.3 -8.6 Citrate synthase (si) (EC 2.3.3.1) compare
GFF824 -2.3 -3.6 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4355 -2.2 -2.0 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF4027 -2.1 -2.4 Flagellar biosynthesis protein FliS compare
GFF389 -2.0 -3.1 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF1032 -2.0 -1.3 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF121 -2.0 -5.5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF1256 -1.9 -5.2 Chromosome (plasmid) partitioning protein ParA compare
GFF2946 -1.9 -4.9 RNA polymerase sigma-54 factor RpoN compare
GFF2881 -1.9 -8.1 WzxE protein compare
GFF3528 -1.8 -3.6 Integration host factor alpha subunit compare
GFF122 -1.7 -9.2 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF3905 -1.7 -6.8 regulator of length of O-antigen component of lipopolysaccharide chains compare
GFF2954 -1.7 -9.2 Aerobic respiration control sensor protein arcB (EC 2.7.3.-) compare
GFF390 -1.6 -2.8 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
GFF241 -1.6 -8.7 ATP-dependent DNA helicase UvrD/PcrA compare
GFF2882 -1.6 -6.6 Lipopolysaccharide biosynthesis protein RffA compare
GFF4600 -1.6 -2.3 SeqA protein, negative modulator of initiation of replication compare
GFF4390 -1.6 -6.3 Recombination protein RecR compare
GFF1716 -1.6 -5.8 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF4192 -1.5 -4.5 DNA-binding protein HU-alpha compare
GFF183 -1.5 -7.5 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
GFF1415 -1.5 -1.4 UPF0337 protein yjbJ compare
GFF4409 -1.5 -7.8 YbbM seven transmembrane helix protein compare
GFF1808 -1.5 -4.2 Mannose-6-phosphate isomerase (EC 5.3.1.8) compare
GFF2389 -1.5 -2.0 Trk system potassium uptake protein TrkA compare
GFF355 -1.4 -2.3 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF4408 -1.4 -6.1 YbbL ABC transporter ATP-binding protein compare
GFF2468 -1.4 -1.9 Putative transmembrane transport protein compare
GFF1699 -1.4 -1.8 BarA-associated response regulator UvrY (= GacA = SirA) compare
GFF2989 -1.3 -8.2 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF34 -1.3 -3.6 FIG01280259: hypothetical protein compare
GFF4643 -1.3 -1.9 hypothetical protein compare
GFF3712 -1.3 -2.7 Cyclic AMP receptor protein compare
GFF2173 -1.3 -5.1 Chromosomal replication initiator protein DnaA compare
GFF3669 -1.3 -1.9 Integration host factor beta subunit compare
GFF2148 -1.3 -2.1 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
GFF2943 -1.2 -2.1 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
GFF2392 -1.2 -2.3 Peptide deformylase (EC 3.5.1.88) compare
GFF1883 -1.2 -4.4 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) compare
GFF1879 -1.2 -7.6 NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3) compare
GFF1737 -1.2 -2.7 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
GFF1886 -1.2 -8.6 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) compare
GFF1881 -1.2 -8.2 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
GFF2149 -1.2 -5.3 Malate dehydrogenase (EC 1.1.1.37) compare
GFF1887 -1.2 -5.5 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) compare
GFF1768 -1.2 -1.1 hypothetical protein compare
GFF2863 -1.1 -1.5 FIG074102: hypothetical protein compare
GFF4601 -1.1 -6.5 Phosphoglucomutase (EC 5.4.2.2) compare
GFF3772 -1.1 -2.0 1-phosphofructokinase (EC 2.7.1.56) compare
GFF2880 -1.1 -6.0 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF55 -1.1 -6.8 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF4537 -1.1 -2.5 CrcB protein compare
GFF1885 -1.1 -5.0 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) compare
GFF2690 -1.1 -1.4 Peptide transport system permease protein SapC compare
GFF3324 -1.0 -1.1 putative periplasmic protein compare
GFF4465 -1.0 -2.2 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA compare
GFF384 -1.0 -1.1 UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,3-glucosyltransferase WaaO (EC 2.4.1.-) compare
GFF2473 -1.0 -3.5 DNA recombination and repair protein RecO compare
GFF2347 -1.0 -5.3 Hydrogen peroxide-inducible genes activator compare
GFF238 -1.0 -4.1 Protein of unknown function DUF484 compare
GFF391 -1.0 -1.6 ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) compare
GFF1880 -1.0 -6.2 NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) compare
GFF4356 -1.0 -3.9 DNA-binding protein HU-beta compare
GFF1890 -1.0 -6.3 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
GFF2434 -1.0 -0.9 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF4243 -1.0 -0.9 Probable secreted protein compare
GFF1900 -1.0 -6.1 Acetate kinase (EC 2.7.2.1) compare
GFF2537 -1.0 -1.8 hypothetical protein compare
GFF1891 -1.0 -1.8 NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) compare
GFF522 -1.0 -4.8 Low-affinity inorganic phosphate transporter compare
GFF4354 -1.0 -3.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF4026 -1.0 -2.9 Flagellar biosynthesis protein FliT compare
GFF4028 -1.0 -3.6 Flagellar hook-associated protein FliD compare
GFF1756 -0.9 -5.8 DNA recombination and repair protein RecF compare
GFF1940 -0.9 -1.4 Putative DNA-binding protein in cluster with Type I restriction-modification system compare
GFF1014 -0.9 -1.3 PTS system, mannose-specific IIC component (EC 2.7.1.69) compare
GFF1884 -0.9 -1.4 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF190 -0.9 -3.3 SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase (EC 2.1.1.182) compare
GFF539 -0.9 -2.9 Putative inner membrane protein compare
GFF87 -0.9 -1.6 C4-type zinc finger protein, DksA/TraR family compare
GFF1889 -0.9 -4.9 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
GFF296 -0.9 -5.0 Multidrug resistance protein D compare
GFF3166 -0.9 -2.9 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase compare
GFF1700 -0.9 -4.9 Excinuclease ABC subunit C compare
GFF158 -0.9 -6.0 Fructose repressor FruR, LacI family compare
GFF3427 -0.9 -3.0 Probable lipoprotein envE precursor compare
GFF1816 -0.9 -2.9 Electron transport complex protein RnfB compare
GFF1429 -0.9 -6.3 Excinuclease ABC subunit A compare
GFF1685 -0.9 -1.9 FIG01045540: hypothetical protein compare
GFF675 -0.9 -6.1 Excinuclease ABC subunit B compare
GFF4379 -0.8 -6.2 RND efflux system, inner membrane transporter CmeB compare
GFF3133 -0.8 -4.6 Putative cell division protein precursor compare
GFF1815 -0.8 -3.0 Electron transport complex protein RnfA compare
GFF4596 -0.8 -2.8 Ferric uptake regulation protein FUR compare
GFF1230 -0.8 -2.1 Salmonella enterica serovar Choleraesuis 50k virulence plasmid DNA, complete sequence compare
GFF1356 -0.8 -1.5 Acetate operon repressor compare
GFF3104 -0.8 -1.0 Hydrogenase maturation protease (EC 3.4.24.-) compare
GFF1882 -0.8 -2.3 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) compare
GFF1901 -0.8 -3.5 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF356 -0.8 -3.2 'tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34)' transl_table=11 compare
GFF3794 -0.8 -4.0 SanA protein compare
GFF1505 -0.8 -3.5 Tryptophan-specific transport protein compare
GFF2566 -0.8 -3.9 Transcriptional regulator, TetR family compare
GFF4628 -0.8 -1.6 putative glycosyltransferase compare
GFF2484 -0.8 -1.0 FIG00639146: hypothetical protein compare
GFF4118 -0.8 -1.5 tRNA-Thr-CGT compare
GFF504 -0.8 -2.0 Putative regulator compare
GFF3397 -0.8 -5.1 Transcription-repair coupling factor compare
GFF4733 -0.8 -0.8 Type III secretion transcriptional regulator HilC (= SirC) compare
GFF845 -0.8 -3.4 Ascorbate utilization transcriptional regulator UlaR, HTH-type compare
GFF1888 -0.8 -2.0 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare
GFF883 -0.8 -5.4 Predicted transcriptional regulator of the myo-inositol catabolic operon compare
GFF2663 -0.8 -1.4 Thiol peroxidase, Tpx-type (EC 1.11.1.15) compare
GFF3845 -0.8 -2.4 putative cytoplasmic protein compare
GFF4244 -0.8 -0.9 Putative outer membrane lipoprotein compare
GFF2967 -0.8 -2.1 ClpXP protease specificity-enhancing factor / Stringent starvation protein B compare
GFF4791 -0.8 -4.7 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
GFF3830 -0.7 -0.9 Uncharacterized protein YehA precursor compare
GFF3506 -0.7 -1.4 6-phospho-beta-glucosidase (EC 3.2.1.86) compare
GFF2219 -0.7 -4.6 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
GFF701 -0.7 -1.2 Hypothetical Zinc-finger containing protein compare
GFF3149 -0.7 -4.8 Type I secretion outer membrane protein, TolC precursor compare
GFF341 -0.7 -0.8 RmbA compare
GFF1966 -0.7 -2.0 FIG00638164: hypothetical protein compare
GFF4122 -0.7 -1.3 FIG01046577: hypothetical protein compare
GFF4380 -0.7 -4.1 Membrane fusion protein of RND family multidrug efflux pump compare
GFF4454 -0.7 -1.0 Transcriptional regulator of fimbriae expression FimZ (LuxR/UhpA family) compare
GFF4279 -0.7 -1.7 protein iraP compare
GFF3599 -0.7 -1.8 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
GFF3533 -0.7 -2.1 FIG00638687: hypothetical protein compare
GFF269 -0.7 -1.9 NAD(P)H-flavin reductase (EC 1.5.1.29) (EC 1.16.1.3) compare
GFF325 -0.7 -2.3 PTS system, gluconate-specific IIB component (EC 2.7.1.69) compare
GFF2679 -0.7 -1.8 Transcriptional repressor protein TyrR compare
GFF2553 -0.7 -1.1 Osmotically inducible protein C compare
GFF1674 -0.7 -1.5 Universal stress protein C compare
GFF2719 -0.7 -2.9 Ribosomal large subunit pseudouridine synthase B (EC 4.2.1.70) compare
GFF2824 -0.7 -1.3 RidA/YER057c/UK114 superfamily, group 2, YoaB-like protein compare
GFF905 -0.7 -1.6 Soluble cytochrome b562 compare
GFF3028 -0.7 -4.1 Transketolase (EC 2.2.1.1) compare
GFF3643 -0.7 -3.2 Electron transport complex protein RnfG compare
GFF509 -0.7 -3.5 Putative phosphosugar-binding protein compare
GFF508 -0.7 -3.5 Transcriptional regulator, GntR family compare
GFF3545 -0.7 -1.1 Transcriptional regulator, AraC family compare
GFF110 -0.7 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF3789 -0.7 -2.7 Galactose/methyl galactoside ABC transport system, ATP-binding protein MglA (EC 3.6.3.17) compare
GFF3644 -0.7 -1.6 Electron transport complex protein RnfD compare
GFF366 -0.7 -2.6 Ribonuclease PH (EC 2.7.7.56) compare
GFF4635 -0.7 -1.2 Succinate dehydrogenase cytochrome b-556 subunit compare
GFF3142 -0.7 -0.9 FIG00896075: hypothetical protein compare
GFF392 -0.7 -1.2 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF4126 -0.7 -0.7 FIG01047407: hypothetical protein compare
GFF4158 -0.7 -1.1 tmRNA-binding protein SmpB compare
GFF1081 -0.7 -3.6 UPF0246 protein YaaA compare
GFF684 -0.7 -1.7 Putative membrane protein compare
GFF603 -0.7 -2.5 NfuA Fe-S protein maturation compare
GFF368 -0.7 -2.2 Transcriptional regulator SlmA, TetR family compare
GFF4411 -0.7 -4.2 Putative NAD(P)-dependent oxidoreductase EC-YbbO compare
GFF3566 -0.7 -1.7 major outer membrane lipoprotein compare
GFF635 -0.7 -2.7 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF928 -0.7 -3.6 Endoribonuclease L-PSP compare
GFF1099 -0.7 -2.5 type 1 fimbriae major subunit FimA compare
GFF4839 -0.6 -4.1 BarA sensory histidine kinase (= VarS = GacS) compare
GFF3744 -0.6 -3.1 O-antigen acetylase compare
GFF2922 -0.6 -1.6 Transcription elongation factor GreA compare
GFF2627 -0.6 -1.1 putative amino acid ABC transporter compare
GFF1504 -0.6 -1.9 DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13) compare
GFF2477 -0.6 -3.3 Translation elongation factor LepA compare
GFF3054 -0.6 -3.6 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
GFF4738 -0.6 -2.3 Type III secretion system protein compare
GFF4639 -0.6 -1.0 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF4096 -0.6 -1.0 FIG01047254: hypothetical protein compare
GFF3823 -0.6 -2.3 Hypothetical lipoprotein yehR compare
GFF3298 -0.6 -0.9 FIG01049236: hypothetical protein compare
GFF4270 -0.6 -0.6 FIG00637869: hypothetical protein compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in lb_plus_sm_buffer experiments

For lb_plus_sm_buffer Kanamycin sulfate across organisms