Experiment set4IT010 for Escherichia coli BW25113

Compare to:

LB with limonene 5 vol%

200 most important genes:

  gene name fitness t score description  
b0462 acrB -3.8 -14.4 multidrug efflux system protein (NCBI) compare
b2392 mntH -3.7 -6.6 manganese transport protein MntH (NCBI) compare
b0683 fur -3.6 -2.4 ferric uptake regulator (NCBI) compare
b3035 tolC -3.4 -8.1 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0463 acrA -3.4 -9.9 multidrug efflux system (NCBI) compare
b4172 hfq -3.0 -2.1 RNA-binding protein Hfq (NCBI) compare
b3631 rfaG -3.0 -14.4 glucosyltransferase I (NCBI) compare
b3792 wzxE -2.8 -8.0 O-antigen translocase (NCBI) compare
b4546 ypeB -2.8 -2.3 hypothetical protein (NCBI) compare
b3630 rfaP -2.7 -10.1 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b2784 relA -2.7 -9.7 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1187 fadR -2.6 -4.9 fatty acid metabolism regulator (NCBI) compare
b3888 yiiD -2.6 -9.2 predicted acetyltransferase (NCBI) compare
b0145 dksA -2.6 -3.5 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2699 recA -2.5 -1.7 recombinase A (NCBI) compare
b3842 rfaH -2.4 -4.8 transcriptional activator RfaH (NCBI) compare
b2346 vacJ -2.3 -7.8 predicted lipoprotein (NCBI) compare
b0222 lpcA -2.2 -2.6 phosphoheptose isomerase (NCBI) compare
b3193 yrbD -2.2 -9.1 predicted ABC-type organic solvent transporter (NCBI) compare
b1236 galU -2.2 -4.8 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2501 ppk -2.1 -9.4 polyphosphate kinase (NCBI) compare
b3935 priA -2.1 -3.7 primosome assembly protein PriA (NCBI) compare
b3163 nlpI -2.1 -4.8 hypothetical protein (NCBI) compare
b0053 surA -2.1 -3.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3052 rfaE -2.1 -3.9 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3195 yrbF -2.1 -10.2 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3194 yrbE -2.0 -10.7 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3192 yrbC -2.0 -8.7 predicted ABC-type organic solvent transporter (NCBI) compare
b3632 rfaQ -2.0 -15.4 lipopolysaccharide core biosynthesis protein (NCBI) compare
b2512 yfgL -2.0 -5.8 protein assembly complex, lipoprotein component (NCBI) compare
b3026 qseC -2.0 -5.2 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0200 gmhB -2.0 -1.3 hypothetical protein (NCBI) compare
b3191 yrbB -1.9 -8.1 orf, hypothetical protein (VIMSS) compare
b3621 rfaC -1.9 -3.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3619 rfaD -1.9 -2.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0737 tolQ -1.9 -2.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0471 ybaB -1.9 -3.9 hypothetical protein (NCBI) compare
b3620 rfaF -1.8 -3.1 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3341 rpsG -1.8 -1.7 30S ribosomal protein S7 (NCBI) compare
b1358 ydaT -1.8 -1.8 Rac prophage; predicted protein (NCBI) compare
b3961 oxyR -1.8 -9.6 DNA-binding transcriptional dual regulator (NCBI) compare
b1830 prc -1.8 -5.3 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b0740 tolB -1.8 -4.9 translocation protein TolB precursor (NCBI) compare
b1130 phoP -1.8 -6.5 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2808 gcvA -1.7 -5.3 DNA-binding transcriptional dual regulator (NCBI) compare
b1095 fabF -1.7 -6.2 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b1007 b1007 -1.7 -1.9 orf, hypothetical protein (VIMSS) compare
b1129 phoQ -1.6 -7.0 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1831 proQ -1.6 -3.6 putative solute/DNA competence effector (NCBI) compare
b1085 b1085 -1.6 -2.0 orf, hypothetical protein (VIMSS) compare
b1863 ruvC -1.6 -3.5 Holliday junction resolvase (NCBI) compare
b2820 recB -1.5 -1.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3398 yrfF -1.5 -2.8 predicted inner membrane protein (NCBI) compare
b3199 yrbK -1.5 -2.4 hypothetical protein (NCBI) compare
b3725 pstB -1.5 -2.2 phosphate transporter subunit (NCBI) compare
b4201 priB -1.5 -2.6 primosomal replication protein N (NCBI) compare
b0739 tolA -1.5 -3.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1848 yebG -1.4 -1.8 conserved protein regulated by LexA (NCBI) compare
b4000 hupA -1.4 -4.1 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b3863 polA -1.4 -1.0 DNA polymerase I (NCBI) compare
b2531 iscR -1.4 -1.9 DNA-binding transcriptional repressor (NCBI) compare
b3609 secB -1.4 -3.3 export protein SecB (NCBI) compare
b4146 yjeK -1.4 -3.5 predicted lysine aminomutase (NCBI) compare
b0738 tolR -1.4 -2.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4515 ybgT -1.4 -1.9 hypothetical protein (NCBI) compare
b3237 argR -1.3 -4.0 arginine repressor (NCBI) compare
b3726 pstA -1.3 -5.0 phosphate transporter subunit (NCBI) compare
b0178 hlpA -1.3 -3.1 periplasmic chaperone (NCBI) compare
b3844 fre -1.3 -4.7 NAD(P)H-flavin reductase (NCBI) compare
b3613 yibP -1.3 -4.7 putative membrane protein (VIMSS) compare
b2293 yfbT -1.3 -2.3 putative phosphatase (VIMSS) compare
b2494 yfgC -1.3 -6.0 predicted peptidase (NCBI) compare
b3811 xerC -1.3 -2.5 site-specific tyrosine recombinase XerC (NCBI) compare
b0623 cspE -1.3 -2.2 cold shock protein E (NCBI) compare
b3205 yhbJ -1.2 -3.4 hypothetical protein (NCBI) compare
b3727 pstC -1.2 -5.2 phosphate transporter subunit (NCBI) compare
b3728 pstS -1.2 -3.5 phosphate transporter subunit (NCBI) compare
b0688 pgm -1.2 -2.9 phosphoglucomutase (NCBI) compare
b1860 ruvB -1.2 -1.1 Holliday junction DNA helicase B (NCBI) compare
b3813 uvrD -1.2 -6.7 DNA-dependent ATPase I and helicase II (NCBI) compare
b0957 ompA -1.2 -3.3 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2822 recC -1.2 -3.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1299 puuR -1.1 -3.6 DNA-binding transcriptional repressor (NCBI) compare
b3627 rfaI -1.1 -8.2 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3409 feoB -1.1 -8.9 ferrous iron transport protein B (NCBI) compare
b2280 nuoJ -1.1 -4.0 NADH dehydrogenase subunit J (NCBI) compare
b2188 yejM -1.1 -6.1 predicted hydrolase, inner membrane (NCBI) compare
b0784 moaD -1.1 -1.4 molybdopterin synthase, small subunit (NCBI) compare
b3644 yicC -1.1 -4.3 hypothetical protein (NCBI) compare
b0741 pal -1.1 -3.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3778 rep -1.1 -5.8 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3784 rfe -1.1 -7.4 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b4042 dgkA -1.1 -2.6 diacylglycerol kinase (NCBI) compare
b0092 ddlB -1.1 -3.7 D-alanylalanine synthetase (NCBI) compare
b0238 gpt -1.0 -2.6 xanthine phosphoribosyltransferase (NCBI) compare
b1109 ndh -1.0 -3.2 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b2906 visC -1.0 -4.2 hypothetical protein (NCBI) compare
b0406 tgt -1.0 -4.9 queuine tRNA-ribosyltransferase (NCBI) compare
b2263 yfbB -1.0 -1.3 predicted peptidase (NCBI) compare
b1729 ydjN -1.0 -2.9 predicted transporter (NCBI) compare
b0430 cyoC -1.0 -2.6 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b1837 yebW -1.0 -2.0 orf, hypothetical protein (VIMSS) compare
b1493 gadB -1.0 -1.7 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b0142 folK -0.9 -1.1 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1591 b1591 -0.9 -1.6 putative oxidoreductase component (VIMSS) compare
b1573 ydfC -0.9 -1.7 Qin prophage; predicted protein (RefSeq) compare
b1861 ruvA -0.9 -1.7 Holliday junction DNA helicase motor protein (NCBI) compare
b1514 lsrC -0.9 -1.7 AI2 transporter (NCBI) compare
b2198 ccmD -0.9 -1.6 cytochrome c biogenesis protein (NCBI) compare
b2620 smpB -0.9 -1.7 SsrA-binding protein (NCBI) compare
b4484 cpxP -0.9 -3.7 periplasmic protein combats stress (NCBI) compare
b3410 yhgG -0.9 -3.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2277 nuoM -0.9 -3.8 NADH dehydrogenase subunit M (NCBI) compare
b2948 yqgE -0.9 -2.4 orf, hypothetical protein (VIMSS) compare
b3408 feoA -0.9 -6.0 ferrous iron transport protein A (NCBI) compare
b1604 ydgH -0.9 -2.4 hypothetical protein (NCBI) compare
b3463 ftsE -0.9 -2.4 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0999 cbpM -0.9 -2.2 modulator of CbpA co-chaperone (NCBI) compare
b3628 rfaB -0.9 -6.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b2741 rpoS -0.8 -3.3 RNA polymerase sigma factor (NCBI) compare
b2295 yfbV -0.8 -3.7 hypothetical protein (NCBI) compare
b1551 b1551 -0.8 -1.8 orf, hypothetical protein (VIMSS) compare
b1263 trpD -0.8 -1.7 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b1709 btuD -0.8 -1.0 vitamin B12-transporter ATPase (NCBI) compare
b1175 minD -0.8 -3.8 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3462 ftsX -0.8 -3.1 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3625 rfaY -0.8 -5.3 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1183 umuD -0.8 -1.5 DNA polymerase V, subunit D (NCBI) compare
b3354 yheU -0.8 -3.2 hypothetical protein (NCBI) compare
b1114 mfd -0.8 -3.9 transcription-repair coupling factor (NCBI) compare
b0858 ybjO -0.8 -1.2 predicted inner membrane protein (NCBI) compare
b3929 rraA -0.8 -4.1 ribonuclease activity regulator protein RraA (NCBI) compare
b1245 oppC -0.8 -3.2 oligopeptide transporter subunit (NCBI) compare
b0429 cyoD -0.8 -2.7 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b2261 menC -0.8 -3.1 O-succinylbenzoate synthase (NCBI) compare
b0431 cyoB -0.8 -4.7 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b3739 atpI -0.8 -3.1 membrane-bound ATP synthase, dispensable protein, affects expression of atpB (VIMSS) compare
b0825 mipB -0.8 -2.5 putative transaldolase (VIMSS) compare
b0209 yafD -0.8 -3.4 hypothetical protein (NCBI) compare
b3002 yqhA -0.7 -1.3 hypothetical protein (NCBI) compare
b0263 afuB -0.7 -1.6 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b0389 yaiA -0.7 -2.0 hypothetical protein (NCBI) compare
b3042 b3042 -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b4596 yciZ -0.7 -1.1 hypothetical protein (RefSeq) compare
b3164 pnp -0.7 -1.7 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3226 yhcK -0.7 -3.1 putative FADA-type transcriptional regulator (VIMSS) compare
b3652 recG -0.7 -4.5 ATP-dependent DNA helicase (NCBI) compare
b0630 lipB -0.7 -1.2 protein of lipoate biosynthesis (VIMSS) compare
b4595 yciY -0.7 -1.2 hypothetical protein (RefSeq) compare
b4613 dinQ -0.7 -1.1 Damage inducible, function unknown (RefSeq) compare
b1824 yobF -0.7 -1.6 hypothetical protein (NCBI) compare
b4509 ylcG -0.7 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b1677 lpp -0.7 -1.6 murein lipoprotein (NCBI) compare
b3785 wzzE -0.7 -4.7 putative transport protein (VIMSS) compare
b4406 yaeP -0.7 -1.3 hypothetical protein (NCBI) compare
b1357 ydaS -0.7 -0.9 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b0641 rlpB -0.7 -1.6 minor lipoprotein (NCBI) compare
b1658 purR -0.7 -3.0 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b0920 ycbC -0.7 -2.5 conserved inner membrane protein (NCBI) compare
b1954 dsrA -0.7 -1.7 regulatory antisense RNA (NCBI) compare
b0428 cyoE -0.7 -3.1 protoheme IX farnesyltransferase (NCBI) compare
b0149 mrcB -0.7 -4.9 penicillin-binding protein 1b (NCBI) compare
b2434 b2434 -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b4438 cyaR -0.7 -1.2 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b4648 ysaC -0.7 -1.1 no description compare
b0998 torD -0.7 -1.1 chaperone protein TorD (NCBI) compare
b1757 b1757 -0.7 -2.4 putative thiosulfate sulfur transferase (VIMSS) compare
b1823 cspC -0.7 -2.0 stress protein, member of the CspA-family (NCBI) compare
b2007 yeeX -0.7 -2.1 conserved protein (RefSeq) compare
b4698 mgrR -0.7 -1.5 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b0440 hupB -0.7 -2.7 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b2952 yggT -0.7 -2.8 predicted inner membrane protein (NCBI) compare
b2614 grpE -0.7 -0.9 heat shock protein (NCBI) compare
b1222 narX -0.7 -2.1 sensory histidine kinase in two-component regulatory system with NarL (NCBI) compare
b2285 nuoE -0.7 -1.2 NADH dehydrogenase subunit E (NCBI) compare
b0890 ftsK -0.7 -3.3 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2824 ygdB -0.7 -2.1 orf, hypothetical protein (VIMSS) compare
b2513 yfgM -0.7 -2.7 hypothetical protein (NCBI) compare
b0088 murD -0.7 -1.2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b4480 hdfR -0.6 -2.5 transcriptional regulator HdfR (NCBI) compare
b0432 cyoA -0.6 -4.1 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b0958 sulA -0.6 -3.3 SOS cell division inhibitor (NCBI) compare
b3021 ygiT -0.6 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1847 yebF -0.6 -1.4 predicted protein (RefSeq) compare
b1325 ycjG -0.6 -2.6 putative muconate cycloisomerase I (EC 5.5.-.-) (VIMSS) compare
b3391 hofQ -0.6 -4.4 predicted fimbrial transporter (NCBI) compare
b1141 ymfG -0.6 -2.3 e14 prophage; predicted excisionase (NCBI) compare
b2930 yggF -0.6 -1.7 predicted hexoseP phosphatase (NCBI) compare
b3228 sspB -0.6 -1.7 ClpXP protease specificity-enhancing factor (NCBI) compare
b1057 yceJ -0.6 -3.9 predicted cytochrome b561 (NCBI) compare
b4505 insX -0.6 -1.0 predicted IS protein (RefSeq) compare
b2450 yffS -0.6 -1.3 CPZ-55 prophage; predicted protein (RefSeq) compare
b4393 trpR -0.6 -3.1 Trp operon repressor (NCBI) compare
b1227 narI -0.6 -3.0 nitrate reductase 1, gamma (cytochrome b(NR)) subunit (NCBI) compare
b0118 acnB -0.6 -1.7 aconitate hydratase (NCBI) compare
b0427 yajR -0.6 -3.7 putative transport protein (VIMSS) compare
b1346 ydaQ -0.6 -2.1 orf, hypothetical protein (VIMSS) compare
b2058 wcaB -0.6 -0.7 predicted acyl transferase (NCBI) compare
b1251 yciI -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b3651 trmH -0.6 -3.2 tRNA (Guanosine-2'-O-)-methyltransferase (NCBI) compare


Specific Phenotypes

For 17 genes in this experiment

For stress limonene in Escherichia coli BW25113

For stress limonene across organisms