Experiment set47IT092 for Escherichia coli BW25113

Compare to:

Koxy_10

200 most important genes:

  gene name fitness t score description  
b0990 cspG -3.4 -2.3 DNA-binding transcriptional regulator (NCBI) compare
b4242 mgtA -3.3 -10.6 magnesium transporter (NCBI) compare
b4685 yrbN -2.3 -5.0 expressed protein (RefSeq) compare
b3162 deaD -2.2 -6.8 inducible ATP-independent RNA helicase (VIMSS) compare
b3261 fis -2.0 -3.2 DNA-binding protein Fis (NCBI) compare
b1130 phoP -2.0 -1.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2318 truA -2.0 -4.3 tRNA pseudouridine synthase A (NCBI) compare
b0439 lon -1.9 -6.1 DNA-binding ATP-dependent protease La (NCBI) compare
b2498 upp -1.9 -4.0 uracil phosphoribosyltransferase (VIMSS) compare
b4146 yjeK -1.8 -2.7 predicted lysine aminomutase (NCBI) compare
b3082 ygjM -1.8 -3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1176 minC -1.7 -4.3 septum formation inhibitor (NCBI) compare
b1861 ruvA -1.7 -2.0 Holliday junction DNA helicase motor protein (NCBI) compare
b2830 nudH -1.7 -2.5 dinucleoside polyphosphate hydrolase (NCBI) compare
b2528 iscA -1.6 -3.0 iron-sulfur cluster assembly protein (NCBI) compare
b0145 dksA -1.6 -3.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4593 ymgI -1.4 -1.3 hypothetical protein (RefSeq) compare
b0630 lipB -1.4 -1.3 protein of lipoate biosynthesis (VIMSS) compare
b4577 sgrS -1.4 -3.1 small antisense RNA (NCBI) compare
b3164 pnp -1.4 -1.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3199 yrbK -1.4 -3.1 hypothetical protein (NCBI) compare
b2567 rnc -1.4 -1.2 ribonuclease III (NCBI) compare
b4699 fnrS -1.4 -1.2 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b3726 pstA -1.4 -5.1 phosphate transporter subunit (NCBI) compare
b4529 ydbJ -1.3 -1.8 hypothetical protein (NCBI) compare
b1175 minD -1.3 -4.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3021 ygiT -1.3 -2.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b3613 yibP -1.3 -4.6 putative membrane protein (VIMSS) compare
b1950 fliR -1.3 -3.9 flagellar biosynthesis protein R (NCBI) compare
b3469 zntA -1.2 -6.8 zinc, cobalt and lead efflux system (NCBI) compare
b0357 yaiN -1.2 -1.8 putative alpha helix chain (VIMSS) compare
b3183 obgE -1.2 -1.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1103 ycfF -1.2 -1.9 orf, hypothetical protein (VIMSS) compare
b4702 mgtL -1.2 -1.0 regulatory leader peptide for mgtA (NCBI) compare
b3916 pfkA -1.2 -2.9 6-phosphofructokinase (NCBI) compare
b0263 afuB -1.2 -1.6 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b1882 cheY -1.1 -0.6 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b2808 gcvA -1.1 -3.3 DNA-binding transcriptional dual regulator (NCBI) compare
b0740 tolB -1.1 -4.2 translocation protein TolB precursor (NCBI) compare
b3778 rep -1.1 -6.5 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b3405 ompR -1.1 -4.2 osmolarity response regulator (NCBI) compare
b2935 tktA -1.1 -2.0 transketolase 1, thiamin-binding (NCBI) compare
b3962 udhA -1.1 -4.4 putative oxidoreductase (VIMSS) compare
b3642 pyrE -1.1 -4.4 orotate phosphoribosyltransferase (NCBI) compare
b3761 trpT -1.1 -1.6 tRNA-Trp (NCBI) compare
b1192 ldcA -1.1 -4.3 L,D-carboxypeptidase A (NCBI) compare
b2504 yfgG -1.1 -1.2 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0014 dnaK -1.0 -2.5 molecular chaperone DnaK (NCBI) compare
b4202 rpsR -1.0 -1.3 30S ribosomal protein S18 (NCBI) compare
b3414 gntY -1.0 -4.2 predicted gluconate transport associated protein (NCBI) compare
b2297 pta -1.0 -0.7 phosphate acetyltransferase (NCBI) compare
b2822 recC -1.0 -4.3 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2699 recA -1.0 -1.2 recombinase A (NCBI) compare
b1346 ydaQ -1.0 -1.4 orf, hypothetical protein (VIMSS) compare
b0881 clpS -1.0 -2.3 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b3728 pstS -1.0 -2.0 phosphate transporter subunit (NCBI) compare
b0683 fur -1.0 -1.7 ferric uptake regulator (NCBI) compare
b2894 xerD -1.0 -1.1 site-specific tyrosine recombinase XerD (NCBI) compare
b4414 tff -1.0 -1.5 unknown RNA (NCBI) compare
b3198 kdsC -1.0 -2.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b2934 cmtB -1.0 -0.9 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b3889 yiiE -1.0 -1.9 predicted transcriptional regulator (RefSeq) compare
b3636 rpmG -1.0 -1.1 50S ribosomal protein L33 (NCBI) compare
b2330 yfcB -1.0 -1.5 putative adenine-specific methylase (VIMSS) compare
b1129 phoQ -1.0 -0.9 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b4520 ymgF -0.9 -1.5 hypothetical protein (NCBI) compare
b3609 secB -0.9 -2.2 export protein SecB (NCBI) compare
b2912 ygfA -0.9 -2.7 putative ligase (VIMSS) compare
b3811 xerC -0.9 -1.8 site-specific tyrosine recombinase XerC (NCBI) compare
b4509 ylcG -0.9 -2.6 DLP12 prophage; predicted protein (NCBI) compare
b2688 gshA -0.9 -5.0 glutamate--cysteine ligase (NCBI) compare
b1025 ycdT -0.9 -1.5 predicted diguanylate cyclase (NCBI) compare
b1196 ycgY -0.9 -2.6 hypothetical protein (NCBI) compare
b0949 uup -0.9 -5.1 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4239 treC -0.9 -1.4 trehalose-6-P hydrolase (NCBI) compare
b3237 argR -0.9 -3.3 arginine repressor (NCBI) compare
b4631 ykgQ -0.9 -1.7 no description compare
b1505 ydeT -0.9 -1.2 hypothetical protein (RefSeq) compare
b2501 ppk -0.8 -5.4 polyphosphate kinase (NCBI) compare
b1257 yciE -0.8 -0.5 hypothetical protein (NCBI) compare
b1827 kdgR -0.8 -2.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b3463 ftsE -0.8 -1.2 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3341 rpsG -0.8 -0.9 30S ribosomal protein S7 (NCBI) compare
b2820 recB -0.8 -1.3 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1579 intQ -0.8 -2.4 Qin prophage; predicted defective integrase (RefSeq) compare
b1613 manA -0.8 -1.5 mannose-6-phosphate isomerase (VIMSS) compare
b2947 gshB -0.8 -2.8 glutathione synthetase (NCBI) compare
b1860 ruvB -0.8 -0.7 Holliday junction DNA helicase B (NCBI) compare
b1712 ihfA -0.8 -1.4 integration host factor subunit alpha (NCBI) compare
b3443 yrhA -0.8 -1.4 orf, hypothetical protein (VIMSS) compare
b4171 miaA -0.8 -1.4 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b4595 yciY -0.8 -1.8 hypothetical protein (RefSeq) compare
b3390 aroK -0.8 -1.5 shikimate kinase I (NCBI) compare
b3292 zntR -0.8 -2.1 zinc-responsive transcriptional regulator (NCBI) compare
b0623 cspE -0.8 -1.7 cold shock protein E (NCBI) compare
b1551 b1551 -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b0082 mraW -0.8 -2.5 S-adenosyl-methyltransferase (NCBI) compare
b3706 trmE -0.7 -3.1 tRNA modification GTPase (NCBI) compare
b4402 yjjY -0.7 -0.7 hypothetical protein (NCBI) compare
b4552 yrhC -0.7 -0.7 no description compare
b3741 gidA -0.7 -2.8 glucose-inhibited division protein A (NCBI) compare
b1409 ynbB -0.7 -0.8 predicted CDP-diglyceride synthase (NCBI) compare
b2448 yffQ -0.7 -3.1 CPZ-55 prophage; predicted protein (RefSeq) compare
b1920 fliY -0.7 -1.9 cystine transporter subunit (NCBI) compare
b0015 dnaJ -0.7 -5.0 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b2329 aroC -0.7 -3.1 chorismate synthase (NCBI) compare
b1676 pykF -0.7 -3.1 pyruvate kinase (NCBI) compare
b1992 cobS -0.7 -2.0 cobalamin synthase (NCBI) compare
b4535 yniD -0.7 -1.2 predicted protein (RefSeq) compare
b4416 rybA -0.7 -1.2 unknown RNA (NCBI) compare
b3623 rfaK -0.7 -1.3 lipopolysaccharide core biosynthesis (NCBI) compare
b0232 yafN -0.7 -0.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1143 ymfI -0.7 -1.7 orf, hypothetical protein (VIMSS) compare
b4410 ecnA -0.7 -1.1 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1778 yeaA -0.7 -1.4 methionine sulfoxide reductase B (NCBI) compare
b4647 mokA -0.7 -0.8 no description compare
b1347 ydaC -0.7 -0.4 Rac prophage; predicted protein (NCBI) compare
b4505 insX -0.7 -1.4 predicted IS protein (RefSeq) compare
b1573 ydfC -0.7 -1.5 Qin prophage; predicted protein (RefSeq) compare
b4458 oxyS -0.7 -1.0 global regulatory RNA (NCBI) compare
b4522 yciX_1 -0.7 -2.0 hypothetical protein (NCBI) compare
b1269 rluB -0.7 -3.4 23S rRNA pseudouridylate synthase (NCBI) compare
b3629 rfaS -0.7 -2.1 lipopolysaccharide core biosynthesis protein (NCBI) compare
b4234 yjgA -0.7 -1.8 hypothetical protein (NCBI) compare
b1434 ydcN -0.7 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b0953 rmf -0.7 -1.6 ribosome modulation factor (NCBI) compare
b1040 csgD -0.7 -0.9 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b1595 ynfL -0.7 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1351 racC -0.7 -0.4 Rac prophage; predicted protein (NCBI) compare
b3977 tyrU -0.7 -0.7 tRNA-Tyr (NCBI) compare
b1727 yniC -0.7 -1.6 predicted hydrolase (NCBI) compare
b0097 yacA -0.6 -2.0 orf, hypothetical protein (VIMSS) compare
b3611 yibN -0.6 -2.3 predicted rhodanese-related sulfurtransferase (NCBI) compare
b3764 yifE -0.6 -2.2 hypothetical protein (NCBI) compare
b3780 rhlB -0.6 -4.8 ATP-dependent RNA helicase (NCBI) compare
b1187 fadR -0.6 -2.1 fatty acid metabolism regulator (NCBI) compare
b1121 ycfZ -0.6 -1.1 predicted inner membrane protein (NCBI) compare
b0535 fimZ -0.6 -2.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1281 pyrF -0.6 -2.3 orotidine 5'-phosphate decarboxylase (NCBI) compare
b1090 plsX -0.6 -2.7 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b1088 yceD -0.6 -2.1 hypothetical protein (NCBI) compare
b1865 nudB -0.6 -1.1 dATP pyrophosphohydrolase (NCBI) compare
b1333 uspE -0.6 -2.0 stress-induced protein (NCBI) compare
b4172 hfq -0.6 -0.4 RNA-binding protein Hfq (NCBI) compare
b4163 glyV -0.6 -1.0 tRNA-Gly (NCBI) compare
b4179 vacB -0.6 -3.1 putative enzyme (VIMSS) compare
b0647 ybeT -0.6 -3.4 conserved outer membrane protein (NCBI) compare
b3260 dusB -0.6 -3.4 tRNA-dihydrouridine synthase B (NCBI) compare
b3625 rfaY -0.6 -2.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0049 apaH -0.6 -1.7 diadenosinetetraphosphatase (NCBI) compare
b0051 ksgA -0.6 -2.7 dimethyladenosine transferase (NCBI) compare
b4096 phnL -0.6 -2.1 carbon-phosphorus lyase complex subunit (NCBI) compare
b1977 asnT -0.6 -2.0 tRNA-Asn (NCBI) compare
b3792 wzxE -0.6 -3.3 O-antigen translocase (NCBI) compare
b1304 pspA -0.6 -1.9 regulatory protein for phage-shock-protein operon (NCBI) compare
b1773 ydjI -0.6 -1.3 predicted aldolase (NCBI) compare
b3806 cyaA -0.6 -2.8 adenylate cyclase (NCBI) compare
b2477 nlpB -0.6 -1.3 lipoprotein-34 (VIMSS) compare
b3101 yqjF -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b0463 acrA -0.6 -4.2 multidrug efflux system (NCBI) compare
b3026 qseC -0.6 -2.2 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1969 yedW -0.6 -2.6 putative 2-component transcriptional regulator (VIMSS) compare
b3781 trxA -0.6 -2.2 thioredoxin 1 (VIMSS) compare
b2263 yfbB -0.6 -1.9 predicted peptidase (NCBI) compare
b2419 yfeK -0.6 -1.6 hypothetical protein (NCBI) compare
b4695 ykgT -0.6 -0.9 no description compare
b0467 priC -0.6 -3.2 primosomal replication protein N'' (NCBI) compare
b1086 rluC -0.6 -3.0 23S rRNA pseudouridylate synthase (NCBI) compare
b3858 yihD -0.6 -1.9 hypothetical protein (NCBI) compare
b1785 yeaI -0.6 -1.6 predicted diguanylate cyclase (NCBI) compare
b0632 dacA -0.6 -3.3 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b1363 trkG -0.6 -0.5 Rac prophage; potassium transporter subunit (NCBI) compare
b3652 recG -0.6 -3.4 ATP-dependent DNA helicase (NCBI) compare
b2168 fruK -0.5 -0.6 1-phosphofructokinase (NCBI) compare
b1612 fumA -0.5 -2.7 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b0436 tig -0.5 -3.6 trigger factor (NCBI) compare
b3387 dam -0.5 -4.2 DNA adenine methylase (NCBI) compare
b2814 metZ -0.5 -1.0 tRNA-Met (NCBI) compare
b4513 kdpF -0.5 -1.6 potassium ion accessory transporter subunit (NCBI) compare
b1871 yecP -0.5 -2.4 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b2466 ypfG -0.5 -2.8 hypothetical protein (NCBI) compare
b1183 umuD -0.5 -0.8 DNA polymerase V, subunit D (NCBI) compare
b4614 sokA -0.5 -1.4 no description compare
b0462 acrB -0.5 -4.5 multidrug efflux system protein (NCBI) compare
b1504 ydeS -0.5 -2.7 predicted fimbrial-like adhesin protein (NCBI) compare
b1567 intK -0.5 -1.4 Qin prophage; predicted protein (RefSeq) compare
b1671 ydhX -0.5 -1.3 predicted 4Fe-4S ferridoxin-type protein (RefSeq) compare
b2754 ygbF -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b2569 lepA -0.5 -2.1 GTP-binding protein LepA (NCBI) compare
b4191 ulaR -0.5 -2.1 DNA-binding transcriptional dual regulator (NCBI) compare
b1104 ycfL -0.5 -0.9 hypothetical protein (NCBI) compare
b2859 ygeO -0.5 -1.2 hypothetical protein (RefSeq) compare
b1669 ydhT -0.5 -2.1 hypothetical protein (NCBI) compare
b1382 ynbE -0.5 -1.0 predicted lipoprotein (NCBI) compare
b4045 yjbJ -0.5 -1.1 predicted stress response protein (NCBI) compare
b0658 ybeX -0.5 -0.3 predicteed ion transport (NCBI) compare
b3644 yicC -0.5 -2.8 hypothetical protein (NCBI) compare
b1677 lpp -0.5 -1.3 murein lipoprotein (NCBI) compare
b0310 ykgH -0.5 -0.6 predicted inner membrane protein (NCBI) compare
b0161 degP -0.5 -2.5 serine endoprotease (protease Do), membrane-associated (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For phage Kanamycin sulfate in Escherichia coli BW25113

For phage Kanamycin sulfate across organisms