Experiment set45IT038 for Escherichia coli BW25113

Compare to:

3 hr rep1_HD100_10fold_dilution

200 most important genes:

  gene name fitness t score description  
b3816 corA -5.8 -15.0 magnesium/nickel/cobalt transporter (NCBI) compare
b0049 apaH -4.2 -5.8 diadenosinetetraphosphatase (NCBI) compare
b3088 alx -3.8 -11.3 predicted inner membrane protein, part of terminus (NCBI) compare
b0222 lpcA -3.6 -5.6 phosphoheptose isomerase (NCBI) compare
b3619 rfaD -3.5 -7.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1493 gadB -3.3 -1.5 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b0737 tolQ -3.1 -5.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1860 ruvB -3.1 -2.1 Holliday junction DNA helicase B (NCBI) compare
b3621 rfaC -3.0 -10.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0738 tolR -2.9 -5.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3052 rfaE -2.8 -8.8 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3979 thrT -2.8 -0.9 tRNA-Thr (NCBI) compare
b3613 yibP -2.7 -7.1 putative membrane protein (VIMSS) compare
b0232 yafN -2.7 -1.2 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0739 tolA -2.6 -6.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1361 ydaW -2.5 -0.8 orf, hypothetical protein (VIMSS) compare
b1863 ruvC -2.4 -3.6 Holliday junction resolvase (NCBI) compare
b1861 ruvA -2.3 -3.0 Holliday junction DNA helicase motor protein (NCBI) compare
b3443 yrhA -2.3 -2.9 orf, hypothetical protein (VIMSS) compare
b4146 yjeK -2.2 -3.3 predicted lysine aminomutase (NCBI) compare
b3290 trkA -2.2 -3.3 potassium transporter peripheral membrane component (NCBI) compare
b4042 dgkA -2.2 -3.5 diacylglycerol kinase (NCBI) compare
b1882 cheY -2.2 -0.9 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b3912 cpxR -2.1 -9.5 DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) compare
b0740 tolB -2.1 -7.3 translocation protein TolB precursor (NCBI) compare
b2567 rnc -2.1 -1.4 ribonuclease III (NCBI) compare
b1936 intG -2.1 -1.7 predicted defective phage integrase (pseudogene) (RefSeq) compare
b0990 cspG -2.0 -1.3 DNA-binding transcriptional regulator (NCBI) compare
b3620 rfaF -2.0 -7.4 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2894 xerD -1.9 -1.3 site-specific tyrosine recombinase XerD (NCBI) compare
b4647 mokA -1.9 -1.2 no description compare
b1192 ldcA -1.8 -6.3 L,D-carboxypeptidase A (NCBI) compare
b1290 sapF -1.8 -2.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2620 smpB -1.8 -1.8 SsrA-binding protein (NCBI) compare
b4701 sokX -1.8 -1.5 sok-related sRNA, function unknown (RefSeq) compare
b1506 yneL -1.8 -2.4 predicted transcriptional regulator (NCBI) compare
b1358 ydaT -1.7 -2.0 Rac prophage; predicted protein (NCBI) compare
b1951 rcsA -1.7 -1.6 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3341 rpsG -1.7 -1.5 30S ribosomal protein S7 (NCBI) compare
b1292 sapC -1.7 -3.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0114 aceE -1.7 -1.9 pyruvate dehydrogenase subunit E1 (NCBI) compare
b4174 hflK -1.7 -10.0 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b4175 hflC -1.7 -9.2 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b1236 galU -1.6 -6.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1258 yciF -1.6 -1.1 hypothetical protein (NCBI) compare
b3791 rffA -1.6 -9.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3792 wzxE -1.6 -8.5 O-antigen translocase (NCBI) compare
b2820 recB -1.6 -2.5 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4481 rffT -1.6 -9.3 4-alpha-L-fucosyltransferase (NCBI) compare
b3261 fis -1.6 -3.0 DNA-binding protein Fis (NCBI) compare
b0200 gmhB -1.5 -2.3 hypothetical protein (NCBI) compare
b3466 yhhL -1.5 -5.6 conserved inner membrane protein (NCBI) compare
b3790 rffC -1.5 -6.5 TDP-fucosamine acetyltransferase (RefSeq) compare
b2935 tktA -1.4 -2.9 transketolase 1, thiamin-binding (NCBI) compare
b4025 pgi -1.4 -7.8 glucose-6-phosphate isomerase (NCBI) compare
b3863 polA -1.4 -1.6 DNA polymerase I (NCBI) compare
b0688 pgm -1.4 -4.8 phosphoglucomutase (NCBI) compare
b2189 proL -1.4 -2.2 tRNA-Pro (NCBI) compare
b2501 ppk -1.4 -8.8 polyphosphate kinase (NCBI) compare
b2808 gcvA -1.4 -4.6 DNA-binding transcriptional dual regulator (NCBI) compare
b1677 lpp -1.4 -2.0 murein lipoprotein (NCBI) compare
b3741 gidA -1.4 -6.0 glucose-inhibited division protein A (NCBI) compare
b1830 prc -1.4 -5.3 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3794 rffM -1.3 -7.0 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b2518 ndk -1.3 -3.1 nucleoside diphosphate kinase (NCBI) compare
b3842 rfaH -1.3 -6.4 transcriptional activator RfaH (NCBI) compare
b3630 rfaP -1.3 -9.7 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1575 dicB -1.3 -1.6 Qin prophage; cell division inhibition protein (NCBI) compare
b4416 rybA -1.3 -1.8 unknown RNA (NCBI) compare
b0890 ftsK -1.3 -5.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1950 fliR -1.3 -3.9 flagellar biosynthesis protein R (NCBI) compare
b2110 yehC -1.3 -1.2 predicted periplasmic pilin chaperone (NCBI) compare
b3387 dam -1.3 -8.8 DNA adenine methylase (NCBI) compare
b1164 ycgZ -1.3 -2.1 hypothetical protein (NCBI) compare
b1176 minC -1.2 -3.9 septum formation inhibitor (NCBI) compare
b2318 truA -1.2 -3.7 tRNA pseudouridine synthase A (NCBI) compare
b3787 rffD -1.2 -8.0 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b4203 rplI -1.2 -4.9 50S ribosomal protein L9 (NCBI) compare
b1175 minD -1.2 -4.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0300 ykgA -1.2 -4.2 putative ARAC-type regulatory protein (VIMSS) compare
b0730 mngR -1.2 -1.8 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1712 ihfA -1.2 -2.3 integration host factor subunit alpha (NCBI) compare
b0437 clpP -1.2 -6.0 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3021 ygiT -1.2 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3977 tyrU -1.1 -1.0 tRNA-Tyr (NCBI) compare
b3786 rffE -1.1 -8.5 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3642 pyrE -1.1 -4.4 orotate phosphoribosyltransferase (NCBI) compare
b0407 yajC -1.1 -2.2 preprotein translocase subunit YajC (NCBI) compare
b0218 yafU -1.1 -3.4 predicted inner membrane protein (RefSeq) compare
b1348 lar -1.1 -2.9 Rac prophage; restriction alleviation protein (NCBI) compare
b1709 btuD -1.1 -0.9 vitamin B12-transporter ATPase (NCBI) compare
b0051 ksgA -1.1 -4.7 dimethyladenosine transferase (NCBI) compare
b3784 rfe -1.1 -8.6 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1334 fnr -1.1 -2.2 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b4172 hfq -1.1 -1.2 RNA-binding protein Hfq (NCBI) compare
b1025 ycdT -1.1 -2.0 predicted diguanylate cyclase (NCBI) compare
b2830 nudH -1.1 -1.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b1161 ycgX -1.1 -1.1 hypothetical protein (NCBI) compare
b1523 yneG -1.1 -2.0 hypothetical protein (NCBI) compare
b0303 ykgI -1.1 -0.7 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -1.1 -1.3 hypothetical protein (NCBI) compare
b1291 sapD -1.1 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2699 recA -1.1 -1.7 recombinase A (NCBI) compare
b3811 xerC -1.1 -2.4 site-specific tyrosine recombinase XerC (NCBI) compare
b4155 yjeA -1.0 -0.7 putative lysyl-tRNA synthetase (VIMSS) compare
b2017 yefM -1.0 -1.7 orf, hypothetical protein (VIMSS) compare
b3631 rfaG -1.0 -7.6 glucosyltransferase I (NCBI) compare
b3839 tatC -1.0 -5.7 TatABCE protein translocation system subunit (NCBI) compare
b3389 aroB -1.0 -6.9 3-dehydroquinate synthase (NCBI) compare
b3390 aroK -1.0 -2.4 shikimate kinase I (NCBI) compare
b1286 rnb -1.0 -2.8 exoribonuclease II (NCBI) compare
b4685 yrbN -1.0 -3.1 expressed protein (RefSeq) compare
b1693 aroD -1.0 -6.2 3-dehydroquinate dehydratase (NCBI) compare
b4375 prfC -1.0 -4.5 peptide chain release factor 3 (NCBI) compare
b2363 yfdT -1.0 -2.3 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2168 fruK -1.0 -1.4 1-phosphofructokinase (NCBI) compare
b2330 yfcB -1.0 -1.6 putative adenine-specific methylase (VIMSS) compare
b3706 trmE -1.0 -4.4 tRNA modification GTPase (NCBI) compare
b3162 deaD -1.0 -4.0 inducible ATP-independent RNA helicase (VIMSS) compare
b0912 ihfB -1.0 -2.9 integration host factor subunit beta (NCBI) compare
b1108 ycfP -0.9 -1.9 orf, hypothetical protein (VIMSS) compare
b4239 treC -0.9 -1.8 trehalose-6-P hydrolase (NCBI) compare
b2528 iscA -0.9 -1.9 iron-sulfur cluster assembly protein (NCBI) compare
b3916 pfkA -0.9 -3.0 6-phosphofructokinase (NCBI) compare
b0406 tgt -0.9 -3.7 queuine tRNA-ribosyltransferase (NCBI) compare
b1968 yedV -0.9 -2.9 predicted sensory kinase in two-component regulatory system with YedW (NCBI) compare
b1480 sra -0.9 -1.3 30S ribosomal subunit protein S22 (NCBI) compare
b3629 rfaS -0.9 -3.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1257 yciE -0.9 -0.5 hypothetical protein (NCBI) compare
b2188 yejM -0.9 -5.0 predicted hydrolase, inner membrane (NCBI) compare
b0889 lrp -0.9 -2.9 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b4640 yoeG -0.9 -2.9 no description compare
b0683 fur -0.9 -1.3 ferric uptake regulator (NCBI) compare
b4655 ythA -0.9 -1.6 expressed protein (RefSeq) compare
b1351 racC -0.9 -0.6 Rac prophage; predicted protein (NCBI) compare
b0706 ybfD -0.9 -2.0 hypothetical protein (NCBI) compare
b3933 ftsN -0.9 -5.5 essential cell division protein (NCBI) compare
b1503 ydeR -0.9 -3.1 predicted fimbrial-like adhesin protein (NCBI) compare
b1346 ydaQ -0.9 -1.6 orf, hypothetical protein (VIMSS) compare
b1850 eda -0.9 -1.9 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3465 yhhF -0.9 -3.7 predicted methyltransferase (NCBI) compare
b3626 rfaJ -0.9 -4.2 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b3438 gntR -0.9 -4.8 DNA-binding transcriptional repressor (NCBI) compare
b3375 yhfR -0.8 -5.5 putative transcriptional regulator (VIMSS) compare
b0015 dnaJ -0.8 -5.0 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b0741 pal -0.8 -3.0 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3205 yhbJ -0.8 -3.4 hypothetical protein (NCBI) compare
b2743 pcm -0.8 -3.3 protein-L-isoaspartate O-methyltransferase (NCBI) compare
b1217 chaB -0.8 -1.5 cation transport regulator (NCBI) compare
b4245 pyrB -0.8 -5.3 aspartate carbamoyltransferase catalytic subunit (NCBI) compare
b3281 aroE -0.8 -6.5 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1502 ydeQ -0.8 -2.1 predicted fimbrial-like adhesin protein (NCBI) compare
b3405 ompR -0.8 -3.9 osmolarity response regulator (NCBI) compare
b1382 ynbE -0.8 -1.3 predicted lipoprotein (NCBI) compare
b1409 ynbB -0.8 -0.7 predicted CDP-diglyceride synthase (NCBI) compare
b3163 nlpI -0.8 -2.9 hypothetical protein (NCBI) compare
b2614 grpE -0.8 -1.8 heat shock protein (NCBI) compare
b0310 ykgH -0.8 -1.2 predicted inner membrane protein (NCBI) compare
b1765 ydjA -0.8 -0.6 predicted oxidoreductase (NCBI) compare
b4497 yeeL -0.8 -0.9 no description compare
b1168 b1168 -0.8 -3.3 putative proteases (VIMSS) compare
b0998 torD -0.8 -1.0 chaperone protein TorD (NCBI) compare
b1074 flgC -0.8 -1.8 flagellar basal-body rod protein C (NCBI) compare
b1293 sapB -0.8 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1429 tehA -0.8 -1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1579 intQ -0.8 -2.8 Qin prophage; predicted defective integrase (RefSeq) compare
b0014 dnaK -0.8 -1.6 molecular chaperone DnaK (NCBI) compare
b2569 lepA -0.8 -3.0 GTP-binding protein LepA (NCBI) compare
b1696 ydiP -0.8 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3623 rfaK -0.8 -1.8 lipopolysaccharide core biosynthesis (NCBI) compare
b1368 ynaA -0.8 -2.6 Rac prophage; predicted tail protein (RefSeq) compare
b0053 surA -0.8 -4.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b4414 tff -0.8 -2.1 unknown RNA (NCBI) compare
b2165 yeiN -0.7 -4.0 hypothetical protein (NCBI) compare
b1160 elbA -0.7 -1.1 hypothetical protein (NCBI) compare
b0888 trxB -0.7 -2.7 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3870 glnA -0.7 -2.6 glutamine synthetase (NCBI) compare
b1877 yecT -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b2642 yfjW -0.7 -0.7 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2024 hisA -0.7 -1.2 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b1205 ychH -0.7 -1.3 predicted inner membrane protein (NCBI) compare
b1727 yniC -0.7 -1.7 predicted hydrolase (NCBI) compare
b2111 yehD -0.7 -2.1 predicted fimbrial-like adhesin protein (NCBI) compare
b3199 yrbK -0.7 -1.5 hypothetical protein (NCBI) compare
b0705 ybfL -0.7 -0.5 putative receptor protein (VIMSS) compare
b4171 miaA -0.7 -2.4 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b0004 thrC -0.7 -5.2 threonine synthase (NCBI) compare
b0499 ylbH -0.7 -3.5 conserved protein, rhs-like (RefSeq) compare
b1730 ydjO -0.7 -1.2 predicted protein (RefSeq) compare
b3210 arcB -0.7 -3.6 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b4312 fimB -0.7 -5.5 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b1399 paaX -0.7 -2.8 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive (NCBI) compare
b3625 rfaY -0.7 -3.6 lipopolysaccharide core biosynthesis protein (NCBI) compare
b2586 yfiM -0.7 -2.8 predicted protein (RefSeq) compare
b3935 priA -0.7 -1.3 primosome assembly protein PriA (NCBI) compare
b1139 lit -0.7 -3.5 e14 prophage; cell death peptidase, inhibitor of T4 late gene expression (NCBI) compare
b0508 hyi -0.7 -2.5 hydroxypyruvate isomerase (NCBI) compare
b1691 ydiN -0.7 -2.7 predicted transporter (RefSeq) compare
b2272 yfbM -0.7 -2.6 hypothetical protein (NCBI) compare
b4699 fnrS -0.7 -0.6 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare


Specific Phenotypes

For 2 genes in this experiment

For predation HD100_bdellovibrio in Escherichia coli BW25113

For predation HD100_bdellovibrio across organisms