Experiment set45IT035 for Escherichia coli BW25113

Compare to:

3 hr rep1_Tiberius_100fold_dilution

200 most important genes:

  gene name fitness t score description  
b3816 corA -5.0 -13.9 magnesium/nickel/cobalt transporter (NCBI) compare
b0049 apaH -4.0 -4.8 diadenosinetetraphosphatase (NCBI) compare
b2620 smpB -3.9 -2.1 SsrA-binding protein (NCBI) compare
b0222 lpcA -3.7 -4.4 phosphoheptose isomerase (NCBI) compare
b3052 rfaE -3.6 -9.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3619 rfaD -3.4 -6.1 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3621 rfaC -3.4 -8.7 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b4535 yniD -3.1 -1.8 predicted protein (RefSeq) compare
b2528 iscA -3.0 -1.7 iron-sulfur cluster assembly protein (NCBI) compare
b4202 rpsR -2.9 -2.6 30S ribosomal protein S18 (NCBI) compare
b3620 rfaF -2.8 -8.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3613 yibP -2.8 -6.0 putative membrane protein (VIMSS) compare
b3443 yrhA -2.7 -2.6 orf, hypothetical protein (VIMSS) compare
b1236 galU -2.7 -6.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b4042 dgkA -2.7 -1.8 diacylglycerol kinase (NCBI) compare
b1346 ydaQ -2.7 -2.1 orf, hypothetical protein (VIMSS) compare
b4520 ymgF -2.6 -2.3 hypothetical protein (NCBI) compare
b2808 gcvA -2.5 -5.5 DNA-binding transcriptional dual regulator (NCBI) compare
b3863 polA -2.3 -1.5 DNA polymerase I (NCBI) compare
b3916 pfkA -2.3 -3.7 6-phosphofructokinase (NCBI) compare
b0739 tolA -2.3 -4.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2820 recB -2.3 -1.5 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3290 trkA -2.2 -1.5 potassium transporter peripheral membrane component (NCBI) compare
b0630 lipB -2.1 -1.4 protein of lipoate biosynthesis (VIMSS) compare
b2935 tktA -2.1 -3.1 transketolase 1, thiamin-binding (NCBI) compare
b1712 ihfA -2.1 -1.2 integration host factor subunit alpha (NCBI) compare
b0200 gmhB -2.1 -2.3 hypothetical protein (NCBI) compare
b1730 ydjO -2.0 -1.0 predicted protein (RefSeq) compare
b1429 tehA -2.0 -1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b3630 rfaP -2.0 -11.6 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3811 xerC -1.9 -2.6 site-specific tyrosine recombinase XerC (NCBI) compare
b4146 yjeK -1.9 -2.9 predicted lysine aminomutase (NCBI) compare
b1291 sapD -1.9 -2.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3631 rfaG -1.8 -12.5 glucosyltransferase I (NCBI) compare
b0890 ftsK -1.8 -5.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0738 tolR -1.8 -3.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4593 ymgI -1.8 -1.0 hypothetical protein (RefSeq) compare
b4025 pgi -1.8 -8.2 glucose-6-phosphate isomerase (NCBI) compare
b2501 ppk -1.8 -9.7 polyphosphate kinase (NCBI) compare
b3629 rfaS -1.7 -4.8 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1160 elbA -1.7 -1.2 hypothetical protein (NCBI) compare
b2330 yfcB -1.7 -2.7 putative adenine-specific methylase (VIMSS) compare
b3842 rfaH -1.7 -5.1 transcriptional activator RfaH (NCBI) compare
b2894 xerD -1.7 -1.0 site-specific tyrosine recombinase XerD (NCBI) compare
b1108 ycfP -1.7 -2.6 orf, hypothetical protein (VIMSS) compare
b4481 rffT -1.6 -6.3 4-alpha-L-fucosyltransferase (NCBI) compare
b0740 tolB -1.6 -5.6 translocation protein TolB precursor (NCBI) compare
b1476 fdnI -1.6 -1.2 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b1677 lpp -1.6 -2.2 murein lipoprotein (NCBI) compare
b0232 yafN -1.6 -0.8 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3741 gidA -1.5 -5.6 glucose-inhibited division protein A (NCBI) compare
b4431 rprA -1.5 -2.3 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b4375 prfC -1.5 -5.3 peptide chain release factor 3 (NCBI) compare
b2699 recA -1.5 -1.7 recombinase A (NCBI) compare
b2376 ypdI -1.5 -3.8 predicted lipoprotein involved in colanic acid biosynthesis (NCBI) compare
b3792 wzxE -1.5 -7.0 O-antigen translocase (NCBI) compare
b1196 ycgY -1.5 -3.9 hypothetical protein (NCBI) compare
b4640 yoeG -1.5 -3.4 no description compare
b3626 rfaJ -1.5 -5.2 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b1258 yciF -1.5 -1.0 hypothetical protein (NCBI) compare
b4541 yehK -1.5 -4.4 hypothetical protein (NCBI) compare
b2318 truA -1.4 -3.4 tRNA pseudouridine synthase A (NCBI) compare
b1739 osmE -1.4 -2.8 DNA-binding transcriptional activator (NCBI) compare
b3082 ygjM -1.4 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b3727 pstC -1.4 -7.5 phosphate transporter subunit (NCBI) compare
b1575 dicB -1.4 -1.4 Qin prophage; cell division inhibition protein (NCBI) compare
b3870 glnA -1.4 -3.5 glutamine synthetase (NCBI) compare
b0722 sdhD -1.3 -4.5 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1503 ydeR -1.3 -3.9 predicted fimbrial-like adhesin protein (NCBI) compare
b0737 tolQ -1.3 -3.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4435 isrC -1.3 -2.0 unknown RNA (NCBI) compare
b0677 nagA -1.3 -5.3 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b2279 nuoK -1.3 -1.7 NADH dehydrogenase subunit K (NCBI) compare
b1482 osmC -1.3 -1.9 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b0889 lrp -1.3 -2.3 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b0806 ybiM -1.3 -1.6 orf, hypothetical protein (VIMSS) compare
b0998 torD -1.3 -1.1 chaperone protein TorD (NCBI) compare
b2071 yegJ -1.2 -1.6 hypothetical protein (NCBI) compare
b3728 pstS -1.2 -3.4 phosphate transporter subunit (NCBI) compare
b1025 ycdT -1.2 -1.9 predicted diguanylate cyclase (NCBI) compare
b4701 sokX -1.2 -0.6 sok-related sRNA, function unknown (RefSeq) compare
b2272 yfbM -1.2 -3.6 hypothetical protein (NCBI) compare
b3791 rffA -1.2 -5.3 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1502 ydeQ -1.2 -2.3 predicted fimbrial-like adhesin protein (NCBI) compare
b1290 sapF -1.2 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3794 rffM -1.2 -5.5 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b0437 clpP -1.2 -5.5 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0721 sdhC -1.2 -2.8 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b1164 ycgZ -1.2 -1.5 hypothetical protein (NCBI) compare
b3021 ygiT -1.1 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b0688 pgm -1.1 -3.5 phosphoglucomutase (NCBI) compare
b4414 tff -1.1 -2.3 unknown RNA (NCBI) compare
b4184 yjfL -1.1 -3.7 conserved inner membrane protein (NCBI) compare
b4653 yicT -1.1 -2.2 no description compare
b4172 hfq -1.1 -1.0 RNA-binding protein Hfq (NCBI) compare
b3625 rfaY -1.1 -4.4 lipopolysaccharide core biosynthesis protein (NCBI) compare
b2830 nudH -1.1 -1.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b1273 yciN -1.1 -1.2 hypothetical protein (NCBI) compare
b1951 rcsA -1.1 -1.2 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b4320 fimH -1.1 -6.0 minor component of type 1 fimbriae (NCBI) compare
b1860 ruvB -1.1 -1.0 Holliday junction DNA helicase B (NCBI) compare
b3786 rffE -1.1 -6.7 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3183 obgE -1.1 -1.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4171 miaA -1.1 -2.9 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2540 hcaC -1.1 -2.7 3-phenylpropionate dioxygenase, predicted ferredoxin subunit (NCBI) compare
b2017 yefM -1.1 -1.1 orf, hypothetical protein (VIMSS) compare
b4191 ulaR -1.1 -3.0 DNA-binding transcriptional dual regulator (NCBI) compare
b1286 rnb -1.1 -1.9 exoribonuclease II (NCBI) compare
b2912 ygfA -1.1 -3.1 putative ligase (VIMSS) compare
b2586 yfiM -1.1 -3.1 predicted protein (RefSeq) compare
b3790 rffC -1.1 -4.0 TDP-fucosamine acetyltransferase (RefSeq) compare
b1651 gloA -1.0 -2.7 glyoxalase I, Ni-dependent (NCBI) compare
b0297 eaeH -1.0 -4.3 attaching and effacing protein, pathogenesis factor (RefSeq) compare
b3706 trmE -1.0 -4.2 tRNA modification GTPase (NCBI) compare
b0533 sfmH -1.0 -5.6 predicted fimbrial-like adhesin protein (RefSeq) compare
b4314 fimA -1.0 -4.3 major type 1 subunit fimbrin (pilin) (NCBI) compare
b1161 ycgX -1.0 -0.8 hypothetical protein (NCBI) compare
b3787 rffD -1.0 -6.5 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1357 ydaS -1.0 -1.5 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b2618 b2618 -1.0 -3.2 orf, hypothetical protein (VIMSS) compare
b4175 hflC -1.0 -6.2 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b3237 argR -1.0 -3.5 arginine repressor (NCBI) compare
b2518 ndk -1.0 -1.9 nucleoside diphosphate kinase (NCBI) compare
b2024 hisA -1.0 -1.9 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b0407 yajC -1.0 -2.4 preprotein translocase subunit YajC (NCBI) compare
b4503 yafF -1.0 -0.6 no description compare
b1493 gadB -1.0 -0.6 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1179 ycgL -1.0 -2.6 conserved protein (NCBI) compare
b4239 treC -1.0 -1.3 trehalose-6-P hydrolase (NCBI) compare
b0683 fur -1.0 -0.9 ferric uptake regulator (NCBI) compare
b4232 fbp -1.0 -5.7 fructose-1,6-bisphosphatase (NCBI) compare
b0438 clpX -1.0 -4.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3387 dam -1.0 -6.4 DNA adenine methylase (NCBI) compare
b3979 thrT -1.0 -0.3 tRNA-Thr (NCBI) compare
b1344 ydaO -1.0 -2.1 predicted C32 tRNA thiolase (NCBI) compare
b4452 gadY -1.0 -5.5 unknown RNA (NCBI) compare
b1175 minD -1.0 -3.6 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0051 ksgA -1.0 -3.4 dimethyladenosine transferase (NCBI) compare
b0053 surA -1.0 -4.6 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3642 pyrE -1.0 -2.5 orotate phosphoribosyltransferase (NCBI) compare
b0902 pflA -1.0 -2.7 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b3933 ftsN -1.0 -5.5 essential cell division protein (NCBI) compare
b2114 metG -0.9 -1.5 methionyl-tRNA synthetase (NCBI) compare
b2859 ygeO -0.9 -2.0 hypothetical protein (RefSeq) compare
b1533 ydeD -0.9 -2.0 orf, hypothetical protein (VIMSS) compare
b0300 ykgA -0.9 -3.1 putative ARAC-type regulatory protein (VIMSS) compare
b4317 fimD -0.9 -8.5 outer membrane usher protein, type 1 fimbrial synthesis (NCBI) compare
b0406 tgt -0.9 -4.1 queuine tRNA-ribosyltransferase (NCBI) compare
b3389 aroB -0.9 -5.8 3-dehydroquinate synthase (NCBI) compare
b0990 cspG -0.9 -1.0 DNA-binding transcriptional regulator (NCBI) compare
b3500 gor -0.9 -1.6 glutathione reductase (NCBI) compare
b1839 yebY -0.9 -2.3 hypothetical protein (NCBI) compare
b1985 yeeO -0.9 -4.3 predicted multidrug efflux system (RefSeq) compare
b1159 mcrA -0.9 -0.8 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b4570 lomR -0.9 -1.6 no description compare
b4426 isrA -0.9 -1.9 unknown RNA (NCBI) compare
b3726 pstA -0.9 -3.1 phosphate transporter subunit (NCBI) compare
b3784 rfe -0.9 -6.5 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b0623 cspE -0.9 -1.4 cold shock protein E (NCBI) compare
b4647 mokA -0.9 -0.6 no description compare
b1724 ydiZ -0.9 -1.6 hypothetical protein (NCBI) compare
b1579 intQ -0.9 -2.7 Qin prophage; predicted defective integrase (RefSeq) compare
b1176 minC -0.9 -2.1 septum formation inhibitor (NCBI) compare
b4588 ylcH -0.9 -1.8 hypothetical protein, DLP12 prophage (RefSeq) compare
b1921 fliZ -0.9 -2.0 orf, hypothetical protein (VIMSS) compare
b4458 oxyS -0.9 -0.9 global regulatory RNA (NCBI) compare
b2369 evgA -0.9 -2.9 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b4316 fimC -0.9 -4.8 periplasmic chaperone, required for type 1 fimbriae (VIMSS) compare
b0303 ykgI -0.9 -0.5 orf, hypothetical protein (VIMSS) compare
b2569 lepA -0.9 -2.6 GTP-binding protein LepA (NCBI) compare
b1862 yebB -0.9 -3.0 orf, hypothetical protein (VIMSS) compare
b2082 ogrK -0.9 -1.2 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b3035 tolC -0.9 -4.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3563 yiaB -0.9 -3.0 orf, hypothetical protein (VIMSS) compare
b1126 potA -0.9 -3.7 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b0364 yaiS -0.9 -2.8 orf, hypothetical protein (VIMSS) compare
b0903 pflB -0.9 -4.9 pyruvate formate lyase I (NCBI) compare
b3889 yiiE -0.8 -1.7 predicted transcriptional regulator (RefSeq) compare
b1847 yebF -0.8 -1.1 predicted protein (RefSeq) compare
b4155 yjeA -0.8 -0.6 putative lysyl-tRNA synthetase (VIMSS) compare
b4460 araH -0.8 -1.8 fused L-arabinose transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b1977 asnT -0.8 -1.5 tRNA-Asn (NCBI) compare
b4139 aspA -0.8 -5.4 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b1679 sufE -0.8 -1.4 cysteine desufuration protein SufE (NCBI) compare
b0542 renD -0.8 -1.8 orf, hypothetical protein (VIMSS) compare
b3162 deaD -0.8 -2.8 inducible ATP-independent RNA helicase (VIMSS) compare
b4174 hflK -0.8 -5.0 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b4545 ypdJ -0.8 -1.3 no description compare
b3961 oxyR -0.8 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b1506 yneL -0.8 -1.1 predicted transcriptional regulator (NCBI) compare
b2274 yfbO -0.8 -3.4 predicted protein (RefSeq) compare
b1861 ruvA -0.8 -0.9 Holliday junction DNA helicase motor protein (NCBI) compare
b0004 thrC -0.8 -5.1 threonine synthase (NCBI) compare
b1950 fliR -0.8 -2.3 flagellar biosynthesis protein R (NCBI) compare
b0530 sfmA -0.8 -2.1 putative fimbrial-like protein (VIMSS) compare
b1693 aroD -0.8 -4.0 3-dehydroquinate dehydratase (NCBI) compare
b2673 nrdH -0.8 -2.5 glutaredoxin-like protein (NCBI) compare
b0044 fixX -0.8 -2.3 predicted 4Fe-4S ferredoxin-type protein (NCBI) compare
b1225 narH -0.8 -3.1 nitrate reductase 1, beta (Fe-S) subunit (NCBI) compare
b1983 yeeN -0.8 -3.9 hypothetical protein (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For predation HD100_bdellovibrio in Escherichia coli BW25113

For predation HD100_bdellovibrio across organisms