Experiment set45IT033 for Escherichia coli BW25113

Compare to:

3 hr rep1_Tiberius_no_dilution

200 most detrimental genes:

  gene name fitness t score description  
b4313 fimE +4.2 24.8 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b2289 lrhA +1.5 8.2 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b2531 iscR +1.4 2.7 DNA-binding transcriptional repressor (NCBI) compare
b0564 appY +1.1 1.6 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b4406 yaeP +0.9 2.9 hypothetical protein (NCBI) compare
b4480 hdfR +0.9 4.5 transcriptional regulator HdfR (NCBI) compare
b1361 ydaW +0.9 0.5 orf, hypothetical protein (VIMSS) compare
b1183 umuD +0.8 2.2 DNA polymerase V, subunit D (NCBI) compare
b1514 lsrC +0.8 1.4 AI2 transporter (NCBI) compare
b1144 ymfJ +0.8 2.2 orf, hypothetical protein (VIMSS) compare
b1266 yciV +0.7 2.2 hypothetical protein (NCBI) compare
b2937 speB +0.7 3.3 agmatinase (NCBI) compare
b1837 yebW +0.7 2.1 orf, hypothetical protein (VIMSS) compare
b3781 trxA +0.7 2.3 thioredoxin 1 (VIMSS) compare
b0850 ybjC +0.7 2.6 predicted inner membrane protein (NCBI) compare
b1684 sufA +0.7 3.0 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b0082 mraW +0.6 2.5 S-adenosyl-methyltransferase (NCBI) compare
b4596 yciZ +0.6 1.0 hypothetical protein (RefSeq) compare
b1390 paaC +0.6 3.1 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b1727 yniC +0.6 1.9 predicted hydrolase (NCBI) compare
b1984 asnW +0.6 1.1 tRNA-Asn (NCBI) compare
b1644 b1644 +0.6 2.0 putative membrane protein (VIMSS) compare
b2236 yfaE +0.6 2.3 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b4568 ytjA +0.6 1.6 predicted protein (RefSeq) compare
b0145 dksA +0.6 1.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1248 b1248 +0.6 2.0 orf, hypothetical protein (VIMSS) compare
b3493 pitA +0.6 3.3 phosphate transporter, low-affinity (NCBI) compare
b2939 yqgB +0.6 1.1 predicted protein (RefSeq) compare
b0101 yacG +0.6 3.1 zinc-binding protein (NCBI) compare
b4454 rdlD +0.6 2.6 sRNA antisense regulator affects LdrD translation; proposed addiction module in LDR-D repeat, with toxic peptide LdrD (RefSeq) compare
b4066 yjcF +0.6 0.5 hypothetical protein (NCBI) compare
b2262 menB +0.6 1.9 naphthoate synthase (NCBI) compare
b3764 yifE +0.5 2.6 hypothetical protein (NCBI) compare
b1643 ydhI +0.5 1.6 predicted inner membrane protein (NCBI) compare
b4592 yccB +0.5 1.1 hypothetical protein (RefSeq) compare
b1559 b1559 +0.5 3.3 orf, hypothetical protein (VIMSS) compare
b4513 kdpF +0.5 0.8 potassium ion accessory transporter subunit (NCBI) compare
b3863 polA +0.5 1.0 DNA polymerase I (NCBI) compare
b3761 trpT +0.5 1.2 tRNA-Trp (NCBI) compare
b1370 insH-5 +0.5 1.2 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b4397 creA +0.5 2.0 hypothetical protein (NCBI) compare
b2684 mprA +0.5 1.5 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) compare
b4506 ykgO +0.5 2.0 rpmJ (L36) paralog (NCBI) compare
b0821 ybiU +0.5 2.3 hypothetical protein (NCBI) compare
b2510 b2510 +0.5 2.3 orf, hypothetical protein (VIMSS) compare
b1782 mipA +0.5 2.8 scaffolding protein for murein synthesizing machinery (NCBI) compare
b2105 yohL +0.5 1.4 hypothetical protein (NCBI) compare
b1548 nohA +0.5 1.0 Qin prophage; predicted packaging protein (RefSeq) compare
b4224 chpS +0.5 2.1 suppressor of inhibitory function of ChpB, PemI-like, autoregulated (VIMSS) compare
b3238 yhcN +0.5 1.7 orf, hypothetical protein (VIMSS) compare
b4561 insM +0.5 2.5 transposase (RefSeq) compare
b1478 adhP +0.5 2.4 alcohol dehydrogenase (VIMSS) compare
b0492 ybbN +0.5 1.6 putative thioredoxin-like protein (VIMSS) compare
b0502 ylbG +0.5 1.7 no description compare
b1890 motA +0.5 0.9 flagellar motor protein MotA (NCBI) compare
b0503 ybbB +0.5 2.1 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b0550 rusA +0.5 1.1 DLP12 prophage; endonuclease RUS (NCBI) compare
b4630 ykgP +0.5 1.5 no description compare
b1337 abgB +0.5 1.7 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b0829 gsiA +0.5 2.8 fused predicted peptide transport subunits of ABC superfamily: ATP-binding components (RefSeq) compare
b1733 chbG +0.5 1.4 hypothetical protein (NCBI) compare
b0439 lon +0.5 2.4 DNA-binding ATP-dependent protease La (NCBI) compare
b2704 srlB +0.5 1.3 glucitol/sorbitol-specific enzyme IIA component of PTS (NCBI) compare
b2205 napG +0.5 2.0 quinol dehydrogenase periplasmic component (NCBI) compare
b2490 b2490 +0.4 1.3 putative protein processing element (VIMSS) compare
b4403 yjtD +0.4 2.1 predicted rRNA methyltransferase (NCBI) compare
b0652 gltL +0.4 2.2 glutamate and aspartate transporter subunit (NCBI) compare
b3268 yhdW +0.4 2.6 predicted amino-acid transporter subunit (NCBI) compare
b1307 pspD +0.4 0.9 peripheral inner membrane phage-shock protein (NCBI) compare
b1287 yciW +0.4 0.9 putative oxidoreductase (VIMSS) compare
b1387 maoC +0.4 2.2 fused aldehyde dehydrogenase/enoyl-CoA hydratase (NCBI) compare
b1678 ynhG +0.4 2.7 hypothetical protein (NCBI) compare
b1148 ymfM +0.4 1.0 e14 prophage; predicted protein (NCBI) compare
b1306 pspC +0.4 1.6 DNA-binding transcriptional activator (NCBI) compare
b1661 cfa +0.4 1.9 cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) (NCBI) compare
b0780 ybhK +0.4 2.4 predicted transferase with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b3643 rph +0.4 2.4 ribonuclease PH (NCBI) compare
b0966 hspQ +0.4 1.8 DNA-binding protein, hemimethylated (RefSeq) compare
b0995 torR +0.4 2.1 DNA-binding response regulator in two-component regulatory system with TorS (NCBI) compare
b4409 blr +0.4 2.2 beta-lactam resistance membrane protein (NCBI) compare
b1803 yeaX +0.4 1.6 predicted oxidoreductase (NCBI) compare
b1855 lpxM +0.4 1.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1007 b1007 +0.4 0.9 orf, hypothetical protein (VIMSS) compare
b3666 uhpT +0.4 2.6 sugar phosphate antiporter (NCBI) compare
b2424 cysU +0.4 1.5 sulfate/thiosulfate transporter subunit (NCBI) compare
b1868 yecE +0.4 1.7 hypothetical protein (NCBI) compare
b1262 trpC +0.4 1.8 N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) compare
b0190 yaeQ +0.4 2.4 hypothetical protein (NCBI) compare
b3150 yraP +0.4 2.3 hypothetical protein (NCBI) compare
b1289 ycjD +0.4 2.0 hypothetical protein (NCBI) compare
b1282 yciH +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b1761 gdhA +0.4 2.0 glutamate dehydrogenase (NCBI) compare
b2642 yfjW +0.4 0.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1233 ychJ +0.4 1.1 hypothetical protein (NCBI) compare
b2673 nrdH +0.4 1.8 glutaredoxin-like protein (NCBI) compare
b0976 hyaE +0.4 1.9 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b2150 mglB +0.4 1.4 methyl-galactoside transporter subunit (NCBI) compare
b2489 hyfI +0.4 1.9 hydrogenase 4, Fe-S subunit (NCBI) compare
b0583 entD +0.4 1.7 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex (NCBI) compare
b2600 tyrA +0.4 2.8 fused chorismate mutase T/prephenate dehydrogenase (NCBI) compare
b0323 yahI +0.4 1.8 predicted carbamate kinase-like protein (NCBI) compare
b1325 ycjG +0.4 1.8 putative muconate cycloisomerase I (EC 5.5.-.-) (VIMSS) compare
b0486 ybaT +0.4 2.2 predicted transporter (NCBI) compare
b0831 yliC +0.4 1.9 predicted peptide transporter subunit: membrane component of ABC superfamily (NCBI) compare
b1412 azoR +0.4 1.6 acyl carrier protein phosphodiesterase (NCBI) compare
b2911 ssrS +0.4 0.8 6S regulatory RNA (NCBI) compare
b2136 yohD +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b4418 sraB +0.4 0.9 unknown RNA (NCBI) compare
b2171 yeiP +0.4 2.3 putative elongation factor (VIMSS) compare
b1507 hipA +0.4 2.2 regulator with hipB (NCBI) compare
b2927 epd +0.4 1.7 D-erythrose 4-phosphate dehydrogenase (NCBI) compare
b1567 intK +0.4 0.9 Qin prophage; predicted protein (RefSeq) compare
b1151 ymfO +0.4 1.2 e14 prophage; conserved protein (RefSeq) compare
b1461 ydcE +0.4 1.1 4-oxalocrotonate tautomerase (NCBI) compare
b1465 narV +0.4 1.0 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b3993 thiE +0.4 2.1 thiamine-phosphate pyrophosphorylase (NCBI) compare
b2005 yeeV +0.4 1.8 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b4378 yjjV +0.4 2.5 predicted DNase (NCBI) compare
b3129 sohA +0.4 1.3 predicted regulator (NCBI) compare
b3451 ugpE +0.4 2.2 glycerol-3-phosphate transporter subunit (NCBI) compare
b1594 dgsA +0.4 1.4 DNA-binding transcriptional repressor (NCBI) compare
b4697 yrdF +0.4 1.6 no description compare
b4012 yjaB +0.4 1.4 predicted acetyltransferase (NCBI) compare
b3098 yqjD +0.4 1.5 hypothetical protein (NCBI) compare
b2222 atoA +0.4 2.4 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit (NCBI) compare
b0643 ybeL +0.4 1.7 hypothetical protein (NCBI) compare
b1833 yebS +0.4 1.7 conserved inner membrane protein (NCBI) compare
b1622 malY +0.4 1.7 bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon (NCBI) compare
b1231 tyrT +0.4 0.5 tRNA-Tyr (NCBI) compare
b1804 rnd +0.4 1.6 ribonuclease D (NCBI) compare
b1085 b1085 +0.4 1.2 orf, hypothetical protein (VIMSS) compare
b2736 ygbJ +0.4 1.8 predicted dehydrogenase, with NAD(P)-binding Rossmann-fold domain (NCBI) compare
b0936 ycbO +0.4 2.0 orf, hypothetical protein (VIMSS) compare
b2229 b2229 +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b2327 yfcA +0.4 2.0 conserved inner membrane protein (NCBI) compare
b0661 miaB +0.4 2.7 isopentenyl-adenosine A37 tRNA methylthiolase (NCBI) compare
b3134 agaW +0.4 1.7 N-acetylgalactosamine-specific enzyme IIC component of PTS, fragment (pseudogene) (RefSeq) compare
b2452 eutH +0.4 2.0 predicted inner membrane protein (NCBI) compare
b1832 yebR +0.4 2.0 free methionine-(R)-sulfoxide reductase (RefSeq) compare
b1066 rimJ +0.4 2.1 ribosomal-protein-S5-alanine N-acetyltransferase (NCBI) compare
b1154 ycfK +0.4 2.3 e14 prophage; predicted protein (NCBI) compare
b0099 mutT +0.4 1.6 nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP (NCBI) compare
b3207 yrbL +0.4 2.1 hypothetical protein (NCBI) compare
b1301 puuB +0.4 2.0 gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding (NCBI) compare
b4522 yciX_1 +0.3 1.3 hypothetical protein (NCBI) compare
b0838 yliJ +0.3 2.3 putative transferase (VIMSS) compare
b4001 yjaH +0.3 2.1 hypothetical protein (NCBI) compare
b0837 yliI +0.3 1.5 predicted dehydrogenase (NCBI) compare
b1224 narG +0.3 2.4 nitrate reductase 1, alpha subunit (NCBI) compare
b0454 ybaZ +0.3 1.1 predicted methyltransferase (NCBI) compare
b2700 ygaD +0.3 1.7 competence damage-inducible protein A (NCBI) compare
b2202 napC +0.3 1.8 nitrate reductase, cytochrome c-type, periplasmic (NCBI) compare
b2006 yeeW +0.3 1.1 CP4-44 prophage; predicted protein (RefSeq) compare
b0610 rnk +0.3 1.0 nucleoside diphosphate kinase regulator (NCBI) compare
b3487 yhiI +0.3 2.3 predicted HlyD family secretion protein (NCBI) compare
b0435 bolA +0.3 1.5 possible regulator of murein genes (VIMSS) compare
b1218 chaC +0.3 1.1 regulatory protein for cation transport (RefSeq) compare
b3582 sgbU +0.3 1.5 probable 3-hexulose-6-phosphate isomerase (VIMSS) compare
b4098 phnJ +0.3 2.2 carbon-phosphorus lyase complex subunit (NCBI) compare
b1225 narH +0.3 1.5 nitrate reductase 1, beta (Fe-S) subunit (NCBI) compare
b3780 rhlB +0.3 2.3 ATP-dependent RNA helicase (NCBI) compare
b1177 ycgJ +0.3 1.8 hypothetical protein (NCBI) compare
b3958 argC +0.3 2.6 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
b2667 ygaV +0.3 2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b4538 yoeF +0.3 0.8 hypothetical protein (RefSeq) compare
b4527 b1354 +0.3 1.9 orf, hypothetical protein (VIMSS) compare
b0876 ybjD +0.3 1.8 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b2481 hyfA +0.3 1.6 hydrogenase 4 Fe-S subunit (VIMSS) compare
b0856 potH +0.3 1.0 putrescine transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2829 ptsP +0.3 2.7 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b3953 frwD +0.3 1.8 predicted enzyme IIB component of PTS (NCBI) compare
b4567 yjjZ +0.3 1.6 hypothetical protein (NCBI) compare
b1602 pntB +0.3 1.6 pyridine nucleotide transhydrogenase (NCBI) compare
b2812 ygdL +0.3 1.4 hypothetical protein (NCBI) compare
b1806 yeaY +0.3 1.4 predicted lipoprotein (NCBI) compare
b1433 b1433 +0.3 1.4 putative membrane transport protein (VIMSS) compare
b2301 yfcF +0.3 1.2 predicted enzyme (NCBI) compare
b2557 purL +0.3 2.3 phosphoribosylformylglycinamidine synthase (NCBI) compare
b0692 potE +0.3 2.0 putrescine/proton symporter: putrescine/ornithine antiporter (NCBI) compare
b0312 betB +0.3 2.0 betaine aldehyde dehydrogenase, NAD-dependent (NCBI) compare
b0131 panD +0.3 1.4 aspartate 1-decarboxylase precursor (NCBI) compare
b3119 tdcR +0.3 0.7 threonine dehydratase operon activator protein (VIMSS) compare
b0806 ybiM +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b4648 ysaC +0.3 1.5 no description compare
b1685 ydiH +0.3 0.5 predicted protein (RefSeq) compare
b1626 b1626 +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b2488 hyfH +0.3 1.4 hydrogenase 4, Fe-S subunit (NCBI) compare
b1774 ydjJ +0.3 2.0 predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI) compare
b0713 ybgL +0.3 1.8 hypothetical protein (NCBI) compare
b0391 yaiE +0.3 1.9 hypothetical protein (NCBI) compare
b3024 ygiW +0.3 1.7 hypothetical protein (NCBI) compare
b1977 asnT +0.3 1.2 tRNA-Asn (NCBI) compare
b0571 cusR +0.3 2.1 DNA-binding response regulator in two-component regulatory system with CusS (NCBI) compare
b2432 yfeY +0.3 1.1 hypothetical protein (NCBI) compare
b3467 yhhM +0.3 1.9 hypothetical protein (NCBI) compare
b2953 yggU +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b0994 torT +0.3 1.5 periplasmic sensory protein associated with the TorRS two-component regulatory system (NCBI) compare
b4371 rsmC +0.3 2.1 16S ribosomal RNA m2G1207 methyltransferase (NCBI) compare
b2916 argP +0.3 1.8 chromosome replication initiation inhibitor protein (NCBI) compare
b1442 ydcU +0.3 1.4 predicted spermidine/putrescine transporter subunit (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For predation HD100_bdellovibrio in Escherichia coli BW25113

For predation HD100_bdellovibrio across organisms