Experiment set43IT004 for Escherichia coli BW25113

Compare to:

T4_T1_phage0

200 most important genes:

  gene name fitness t score description  
b1765 ydjA -3.7 -1.3 predicted oxidoreductase (NCBI) compare
b4655 ythA -3.2 -1.3 expressed protein (RefSeq) compare
b3839 tatC -2.7 -10.1 TatABCE protein translocation system subunit (NCBI) compare
b4201 priB -2.6 -3.7 primosomal replication protein N (NCBI) compare
b1573 ydfC -2.4 -1.4 Qin prophage; predicted protein (RefSeq) compare
b0439 lon -2.4 -7.2 DNA-binding ATP-dependent protease La (NCBI) compare
b2894 xerD -2.1 -1.1 site-specific tyrosine recombinase XerD (NCBI) compare
b0630 lipB -2.0 -1.9 protein of lipoate biosynthesis (VIMSS) compare
b4520 ymgF -1.9 -1.8 hypothetical protein (NCBI) compare
b0564 appY -1.9 -1.2 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b2897 ygfY -1.8 -4.0 hypothetical protein (NCBI) compare
b1286 rnb -1.8 -2.9 exoribonuclease II (NCBI) compare
b0721 sdhC -1.8 -6.9 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b0726 sucA -1.6 -4.0 alpha-ketoglutarate decarboxylase (NCBI) compare
b3979 thrT -1.6 -0.4 tRNA-Thr (NCBI) compare
b3169 nusA -1.6 -1.8 transcription elongation factor NusA (NCBI) compare
b1291 sapD -1.6 -1.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1860 ruvB -1.6 -0.8 Holliday junction DNA helicase B (NCBI) compare
b0990 cspG -1.6 -0.8 DNA-binding transcriptional regulator (NCBI) compare
b4685 yrbN -1.5 -2.8 expressed protein (RefSeq) compare
b0728 sucC -1.5 -6.7 succinyl-CoA synthetase subunit beta (NCBI) compare
b2287 nuoB -1.5 -6.2 NADH dehydrogenase subunit B (NCBI) compare
b2288 nuoA -1.5 -2.5 NADH dehydrogenase I chain A (VIMSS) compare
b0739 tolA -1.4 -2.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0200 gmhB -1.4 -1.6 hypothetical protein (NCBI) compare
b2285 nuoE -1.4 -2.5 NADH dehydrogenase subunit E (NCBI) compare
b1575 dicB -1.4 -0.9 Qin prophage; cell division inhibition protein (NCBI) compare
b3229 sspA -1.4 -2.9 stringent starvation protein A (NCBI) compare
b2286 nuoC -1.4 -4.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3621 rfaC -1.4 -5.5 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3863 polA -1.4 -0.8 DNA polymerase I (NCBI) compare
b2330 yfcB -1.4 -1.1 putative adenine-specific methylase (VIMSS) compare
b2276 nuoN -1.4 -4.8 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2279 nuoK -1.4 -2.1 NADH dehydrogenase subunit K (NCBI) compare
b2567 rnc -1.3 -0.7 ribonuclease III (NCBI) compare
b0890 ftsK -1.3 -3.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b4139 aspA -1.3 -8.5 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2281 nuoI -1.3 -2.5 NADH dehydrogenase subunit I (NCBI) compare
b0723 sdhA -1.3 -8.5 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b2168 fruK -1.3 -1.9 1-phosphofructokinase (NCBI) compare
b1936 intG -1.3 -0.8 predicted defective phage integrase (pseudogene) (RefSeq) compare
b3613 yibP -1.3 -1.8 putative membrane protein (VIMSS) compare
b1062 pyrC -1.3 -7.3 dihydroorotase (NCBI) compare
b2282 nuoH -1.3 -3.3 NADH dehydrogenase subunit H (NCBI) compare
b3545 proK -1.3 -1.9 tRNA-Pro (NCBI) compare
b3636 rpmG -1.3 -1.9 50S ribosomal protein L33 (NCBI) compare
b1161 ycgX -1.3 -0.5 hypothetical protein (NCBI) compare
b2283 nuoG -1.3 -7.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3778 rep -1.3 -5.7 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b4171 miaA -1.3 -1.2 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b4006 purH -1.2 -7.7 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b0724 sdhB -1.2 -7.4 succinate dehydrogenase, FeS subunit (NCBI) compare
b3236 mdh -1.2 -6.6 malate dehydrogenase (NCBI) compare
b0738 tolR -1.2 -2.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0049 apaH -1.2 -2.9 diadenosinetetraphosphatase (NCBI) compare
b2278 nuoL -1.2 -7.9 NADH dehydrogenase subunit L (NCBI) compare
b0722 sdhD -1.2 -3.1 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b0145 dksA -1.2 -2.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1160 elbA -1.2 -0.9 hypothetical protein (NCBI) compare
b1612 fumA -1.2 -3.7 fumarate hydratase (fumarase A), aerobic Class I (NCBI) compare
b0737 tolQ -1.2 -1.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3341 rpsG -1.1 -1.2 30S ribosomal protein S7 (NCBI) compare
b2280 nuoJ -1.1 -3.8 NADH dehydrogenase subunit J (NCBI) compare
b3652 recG -1.1 -5.9 ATP-dependent DNA helicase (NCBI) compare
b1882 cheY -1.1 -0.2 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b4603 rseX -1.1 -0.7 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2424 cysU -1.1 -3.0 sulfate/thiosulfate transporter subunit (NCBI) compare
b3870 glnA -1.1 -2.5 glutamine synthetase (NCBI) compare
b3609 secB -1.1 -2.4 export protein SecB (NCBI) compare
b2284 nuoF -1.1 -4.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1874 cutC -1.1 -2.6 copper homeostasis protein (NCBI) compare
b2277 nuoM -1.1 -5.6 NADH dehydrogenase subunit M (NCBI) compare
b3390 aroK -1.1 -1.0 shikimate kinase I (NCBI) compare
b1129 phoQ -1.1 -2.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b4232 fbp -1.1 -7.4 fructose-1,6-bisphosphatase (NCBI) compare
b0053 surA -1.1 -2.3 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1025 ycdT -1.1 -0.7 predicted diguanylate cyclase (NCBI) compare
b3792 wzxE -1.1 -4.2 O-antigen translocase (NCBI) compare
b2576 srmB -1.1 -2.1 ATP-dependent RNA helicase (NCBI) compare
b0720 gltA -1.1 -5.1 citrate synthase (NCBI) compare
b1192 ldcA -1.0 -3.7 L,D-carboxypeptidase A (NCBI) compare
b0522 purK -1.0 -5.7 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b1693 aroD -1.0 -3.6 3-dehydroquinate dehydratase (NCBI) compare
b1176 minC -1.0 -2.1 septum formation inhibitor (NCBI) compare
b2935 tktA -1.0 -1.1 transketolase 1, thiamin-binding (NCBI) compare
b1418 cybB -1.0 -3.0 cytochrome b(561) (VIMSS) compare
b4458 oxyS -1.0 -1.0 global regulatory RNA (NCBI) compare
b2951 yggS -1.0 -2.8 predicted enzyme (NCBI) compare
b0471 ybaB -1.0 -1.8 hypothetical protein (NCBI) compare
b1804 rnd -1.0 -3.4 ribonuclease D (NCBI) compare
b0928 aspC -1.0 -4.3 aspartate aminotransferase, PLP-dependent (NCBI) compare
b3620 rfaF -0.9 -3.7 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1679 sufE -0.9 -3.3 cysteine desufuration protein SufE (NCBI) compare
b0945 pyrD -0.9 -5.4 dihydroorotate dehydrogenase (NCBI) compare
b1762 b1762 -0.9 -1.4 orf, hypothetical protein (VIMSS) compare
b2414 cysK -0.9 -7.2 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b3811 xerC -0.9 -0.9 site-specific tyrosine recombinase XerC (NCBI) compare
b1524 yneH -0.9 -0.6 predicted glutaminase (NCBI) compare
b4503 yafF -0.9 -0.3 no description compare
b2912 ygfA -0.9 -2.2 putative ligase (VIMSS) compare
b4179 vacB -0.9 -3.7 putative enzyme (VIMSS) compare
b3290 trkA -0.9 -1.7 potassium transporter peripheral membrane component (NCBI) compare
b3026 qseC -0.9 -2.8 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1744 astE -0.9 -3.7 succinylglutamate desuccinylase (NCBI) compare
b1628 rsxB -0.9 -1.2 electron transport complex protein RnfB (NCBI) compare
b3052 rfaE -0.9 -3.1 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0920 ycbC -0.9 -3.7 conserved inner membrane protein (NCBI) compare
b1333 uspE -0.9 -3.3 stress-induced protein (NCBI) compare
b3414 gntY -0.8 -3.6 predicted gluconate transport associated protein (NCBI) compare
b2565 recO -0.8 -4.3 DNA repair protein RecO (NCBI) compare
b1983 yeeN -0.8 -3.6 hypothetical protein (NCBI) compare
b0080 fruR -0.8 -4.5 DNA-binding transcriptional dual regulator (NCBI) compare
b2136 yohD -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b3838 tatB -0.8 -3.6 sec-independent translocase (NCBI) compare
b2498 upp -0.8 -1.8 uracil phosphoribosyltransferase (VIMSS) compare
b2114 metG -0.8 -1.4 methionyl-tRNA synthetase (NCBI) compare
b3199 yrbK -0.8 -2.8 hypothetical protein (NCBI) compare
b0729 sucD -0.8 -2.5 succinyl-CoA synthetase subunit alpha (NCBI) compare
b1344 ydaO -0.8 -1.6 predicted C32 tRNA thiolase (NCBI) compare
b1583 ynfB -0.8 -1.9 hypothetical protein (NCBI) compare
b1563 relE -0.8 -1.9 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1279 yciS -0.8 -0.8 conserved inner membrane protein (NCBI) compare
b3617 kbl -0.8 -4.5 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) compare
b1235 rssB -0.8 -4.1 response regulator of RpoS (NCBI) compare
b4481 rffT -0.8 -2.5 4-alpha-L-fucosyltransferase (NCBI) compare
b2762 cysH -0.8 -4.8 phosphoadenosine phosphosulfate reductase (NCBI) compare
b1968 yedV -0.8 -1.9 predicted sensory kinase in two-component regulatory system with YedW (NCBI) compare
b3791 rffA -0.8 -2.5 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0589 fepG -0.7 -2.7 iron-enterobactin transporter subunit (NCBI) compare
b2501 ppk -0.7 -3.8 polyphosphate kinase (NCBI) compare
b1281 pyrF -0.7 -1.5 orotidine 5'-phosphate decarboxylase (NCBI) compare
b3642 pyrE -0.7 -3.3 orotate phosphoribosyltransferase (NCBI) compare
b0429 cyoD -0.7 -2.5 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b4436 ryeC -0.7 -1.0 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b2859 ygeO -0.7 -1.4 hypothetical protein (RefSeq) compare
b2301 yfcF -0.7 -2.8 predicted enzyme (NCBI) compare
b1219 ychN -0.7 -1.8 hypothetical protein (NCBI) compare
b1730 ydjO -0.7 -0.3 predicted protein (RefSeq) compare
b1175 minD -0.7 -2.0 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2499 purM -0.7 -3.5 phosphoribosylaminoimidazole synthetase (NCBI) compare
b2343 b2343 -0.7 -0.9 orf, hypothetical protein (VIMSS) compare
b2966 yqgA -0.7 -2.9 predicted inner membrane protein (NCBI) compare
b1182 hlyE -0.7 -0.4 hemolysin E (VIMSS) compare
b0142 folK -0.7 -0.1 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4640 yoeG -0.7 -0.8 no description compare
b1811 yoaH -0.7 -1.3 hypothetical protein (NCBI) compare
b2564 pdxJ -0.7 -1.9 pyridoxal phosphate biosynthetic protein (NCBI) compare
b4041 plsB -0.7 -1.1 glycerol-3-phosphate acyltransferase (VIMSS) compare
b1292 sapC -0.7 -1.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0740 tolB -0.7 -1.7 translocation protein TolB precursor (NCBI) compare
b0585 fes -0.7 -2.4 enterobactin/ferric enterobactin esterase (NCBI) compare
b4048 yjbM -0.7 -0.5 hypothetical protein (NCBI) compare
b1252 tonB -0.7 -1.7 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b1084 rne -0.7 -2.9 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4239 treC -0.7 -0.8 trehalose-6-P hydrolase (NCBI) compare
b3405 ompR -0.7 -2.2 osmolarity response regulator (NCBI) compare
b3706 trmE -0.7 -1.9 tRNA modification GTPase (NCBI) compare
b3933 ftsN -0.7 -3.6 essential cell division protein (NCBI) compare
b1125 potB -0.7 -1.8 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b2189 proL -0.7 -0.7 tRNA-Pro (NCBI) compare
b3198 kdsC -0.7 -1.5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3649 rpoZ -0.7 -1.3 DNA-directed RNA polymerase subunit omega (NCBI) compare
b2188 yejM -0.7 -3.9 predicted hydrolase, inner membrane (NCBI) compare
b0889 lrp -0.6 -1.6 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b4538 yoeF -0.6 -0.9 hypothetical protein (RefSeq) compare
b1690 ydiM -0.6 -0.6 predicted transporter (NCBI) compare
b2808 gcvA -0.6 -2.2 DNA-binding transcriptional dual regulator (NCBI) compare
b0432 cyoA -0.6 -4.2 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b1171 b1171 -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b1324 tpx -0.6 -2.5 thiol peroxidase (NCBI) compare
b3816 corA -0.6 -3.4 magnesium/nickel/cobalt transporter (NCBI) compare
b1760 ynjH -0.6 -1.6 hypothetical protein (NCBI) compare
b4214 cysQ -0.6 -4.2 PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) compare
b3582 sgbU -0.6 -2.7 probable 3-hexulose-6-phosphate isomerase (VIMSS) compare
b1390 paaC -0.6 -1.2 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b0957 ompA -0.6 -1.4 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b1607 ydgC -0.6 -1.0 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b3844 fre -0.6 -2.2 NAD(P)H-flavin reductase (NCBI) compare
b4203 rplI -0.6 -2.5 50S ribosomal protein L9 (NCBI) compare
b1409 ynbB -0.6 -0.3 predicted CDP-diglyceride synthase (NCBI) compare
b0683 fur -0.6 -0.6 ferric uptake regulator (NCBI) compare
b3098 yqjD -0.6 -2.1 hypothetical protein (NCBI) compare
b0746 valZ -0.6 -1.4 tRNA-Val (NCBI) compare
b0685 ybfE -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b1363 trkG -0.6 -0.3 Rac prophage; potassium transporter subunit (NCBI) compare
b3790 rffC -0.6 -1.3 TDP-fucosamine acetyltransferase (RefSeq) compare
b0605 ahpC -0.6 -2.4 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b3389 aroB -0.6 -4.1 3-dehydroquinate synthase (NCBI) compare
b0751 pnuC -0.6 -2.2 predicted nicotinamide mononucleotide transporter (NCBI) compare
b3630 rfaP -0.6 -4.1 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1497 b1497 -0.6 -0.3 putative enzyme (VIMSS) compare
b1499 ydeO -0.6 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1248 b1248 -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b1545 pinQ -0.6 -0.1 Qin prophage; predicted site-specific recombinase (NCBI) compare
b3129 sohA -0.6 -1.4 predicted regulator (NCBI) compare
b3281 aroE -0.6 -4.3 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1989 asnV -0.6 -1.4 tRNA-Asn (NCBI) compare
b1551 b1551 -0.6 -0.2 orf, hypothetical protein (VIMSS) compare
b2903 gcvP -0.6 -4.5 glycine dehydrogenase (NCBI) compare
b3082 ygjM -0.6 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in nophagecontrol experiments

For nophagecontrol NoPhageControl across organisms