| | gene | name | fitness | t score | description | |
|---|
| b4053 | alr | -7.5 | -14.3 | alanine racemase (NCBI) | compare |
| b0463 | acrA | -6.5 | -23.3 | multidrug efflux system (NCBI) | compare |
| b0462 | acrB | -6.4 | -31.9 | multidrug efflux system protein (NCBI) | compare |
| b4237 | nrdG | -5.4 | -7.3 | anaerobic ribonucleotide reductase activating protein (NCBI) | compare |
| b4238 | nrdD | -5.0 | -12.8 | anaerobic ribonucleoside triphosphate reductase (NCBI) | compare |
| b4041 | plsB | -4.4 | -5.2 | glycerol-3-phosphate acyltransferase (VIMSS) | compare |
| b1334 | fnr | -2.6 | -3.6 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |
| b3035 | tolC | -2.4 | -2.8 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b4025 | pgi | -2.3 | -12.4 | glucose-6-phosphate isomerase (NCBI) | compare |
| b1192 | ldcA | -2.2 | -2.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b1850 | eda | -2.0 | -2.3 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b0386 | proC | -1.7 | -6.1 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b4201 | priB | -1.7 | -4.2 | primosomal replication protein N (NCBI) | compare |
| b1187 | fadR | -1.6 | -3.1 | fatty acid metabolism regulator (NCBI) | compare |
| b0243 | proA | -1.5 | -9.6 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0149 | mrcB | -1.4 | -11.2 | penicillin-binding protein 1b (NCBI) | compare |
| b0949 | uup | -1.3 | -8.6 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b2820 | recB | -1.3 | -0.9 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b4402 | yjjY | -1.3 | -1.3 | hypothetical protein (NCBI) | compare |
| b4202 | rpsR | -1.3 | -2.5 | 30S ribosomal protein S18 (NCBI) | compare |
| b0303 | ykgI | -1.3 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b0242 | proB | -1.3 | -5.8 | gamma-glutamyl kinase (NCBI) | compare |
| b3792 | wzxE | -1.3 | -7.7 | O-antigen translocase (NCBI) | compare |
| b2830 | nudH | -1.2 | -1.8 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b0902 | pflA | -1.2 | -6.2 | pyruvate formate lyase activating enzyme 1 (NCBI) | compare |
| b0739 | tolA | -1.1 | -2.9 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b0912 | ihfB | -1.1 | -2.0 | integration host factor subunit beta (NCBI) | compare |
| b0053 | surA | -1.1 | -6.7 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b1292 | sapC | -1.1 | -2.8 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0737 | tolQ | -1.0 | -2.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3781 | trxA | -1.0 | -4.2 | thioredoxin 1 (VIMSS) | compare |
| b4535 | yniD | -1.0 | -1.9 | predicted protein (RefSeq) | compare |
| b1551 | b1551 | -1.0 | -0.6 | orf, hypothetical protein (VIMSS) | compare |
| b3868 | glnG | -1.0 | -6.7 | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | compare |
| b2699 | recA | -1.0 | -0.6 | recombinase A (NCBI) | compare |
| b1863 | ruvC | -1.0 | -1.5 | Holliday junction resolvase (NCBI) | compare |
| b2894 | xerD | -1.0 | -0.6 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b2168 | fruK | -0.9 | -1.0 | 1-phosphofructokinase (NCBI) | compare |
| b0688 | pgm | -0.9 | -3.3 | phosphoglucomutase (NCBI) | compare |
| b0167 | glnD | -0.9 | -3.9 | PII uridylyl-transferase (NCBI) | compare |
| b0728 | sucC | -0.9 | -5.8 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b1712 | ihfA | -0.9 | -0.8 | integration host factor subunit alpha (NCBI) | compare |
| b2576 | srmB | -0.9 | -3.4 | ATP-dependent RNA helicase (NCBI) | compare |
| b1860 | ruvB | -0.9 | -1.1 | Holliday junction DNA helicase B (NCBI) | compare |
| b3935 | priA | -0.9 | -3.7 | primosome assembly protein PriA (NCBI) | compare |
| b4177 | purA | -0.9 | -2.1 | adenylosuccinate synthetase (NCBI) | compare |
| b2330 | yfcB | -0.9 | -1.2 | putative adenine-specific methylase (VIMSS) | compare |
| b1124 | potC | -0.8 | -4.4 | spermidine/putrescine ABC transporter membrane protein (NCBI) | compare |
| b1347 | ydaC | -0.8 | -0.5 | Rac prophage; predicted protein (NCBI) | compare |
| b0903 | pflB | -0.8 | -6.5 | pyruvate formate lyase I (NCBI) | compare |
| b1855 | lpxM | -0.8 | -3.2 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b3390 | aroK | -0.8 | -1.7 | shikimate kinase I (NCBI) | compare |
| b1290 | sapF | -0.8 | -1.6 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4701 | sokX | -0.8 | -1.1 | sok-related sRNA, function unknown (RefSeq) | compare |
| b2024 | hisA | -0.8 | -2.6 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b2531 | iscR | -0.8 | -2.2 | DNA-binding transcriptional repressor (NCBI) | compare |
| b2528 | iscA | -0.8 | -1.9 | iron-sulfur cluster assembly protein (NCBI) | compare |
| b2110 | yehC | -0.8 | -1.6 | predicted periplasmic pilin chaperone (NCBI) | compare |
| b1259 | yciG | -0.8 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b2659 | b2659 | -0.8 | -3.1 | orf, hypothetical protein (VIMSS) | compare |
| b0729 | sucD | -0.7 | -4.2 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b1175 | minD | -0.7 | -4.1 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b3636 | rpmG | -0.7 | -1.7 | 50S ribosomal protein L33 (NCBI) | compare |
| b2814 | metZ | -0.7 | -1.8 | tRNA-Met (NCBI) | compare |
| b2912 | ygfA | -0.7 | -2.1 | putative ligase (VIMSS) | compare |
| b0741 | pal | -0.7 | -2.5 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0232 | yafN | -0.7 | -0.8 | predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) | compare |
| b0908 | aroA | -0.7 | -4.8 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2313 | cvpA | -0.7 | -4.7 | membrane protein required for colicin V production (NCBI) | compare |
| b1293 | sapB | -0.7 | -1.7 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1125 | potB | -0.7 | -3.2 | spermidine/putrescine ABC transporter membrane protein (NCBI) | compare |
| b0237 | pepD | -0.7 | -5.5 | aminoacyl-histidine dipeptidase (peptidase D) (NCBI) | compare |
| b1861 | ruvA | -0.7 | -1.0 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b4647 | mokA | -0.7 | -1.0 | no description | compare |
| b1105 | ycfM | -0.7 | -2.7 | predicted outer membrane lipoprotein (NCBI) | compare |
| b0142 | folK | -0.7 | -0.6 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b0603 | ybdO | -0.7 | -0.4 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b4375 | prfC | -0.7 | -2.1 | peptide chain release factor 3 (NCBI) | compare |
| b3229 | sspA | -0.7 | -1.8 | stringent starvation protein A (NCBI) | compare |
| b2215 | ompC | -0.7 | -4.7 | outer membrane porin protein C (NCBI) | compare |
| b2329 | aroC | -0.7 | -3.3 | chorismate synthase (NCBI) | compare |
| b1236 | galU | -0.7 | -3.1 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b0234 | yafP | -0.7 | -1.6 | predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) | compare |
| b2297 | pta | -0.7 | -0.6 | phosphate acetyltransferase (NCBI) | compare |
| b3405 | ompR | -0.7 | -2.7 | osmolarity response regulator (NCBI) | compare |
| b1176 | minC | -0.7 | -1.7 | septum formation inhibitor (NCBI) | compare |
| b1123 | potD | -0.7 | -3.5 | spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) | compare |
| b3162 | deaD | -0.6 | -3.4 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b1129 | phoQ | -0.6 | -1.3 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b1648 | b1648 | -0.6 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b2620 | smpB | -0.6 | -1.0 | SsrA-binding protein (NCBI) | compare |
| b2553 | glnB | -0.6 | -3.1 | regulatory protein P-II for glutamine synthetase (NCBI) | compare |
| b3930 | menA | -0.6 | -5.4 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) | compare |
| b0118 | acnB | -0.6 | -0.6 | aconitate hydratase (NCBI) | compare |
| b1497 | b1497 | -0.6 | -0.3 | putative enzyme (VIMSS) | compare |
| b1593 | b1593 | -0.6 | -2.7 | orf, hypothetical protein (VIMSS) | compare |
| b1271 | yciK | -0.6 | -1.7 | short chain dehydrogenase (NCBI) | compare |
| b4593 | ymgI | -0.6 | -0.7 | hypothetical protein (RefSeq) | compare |
| b3493 | pitA | -0.6 | -4.1 | phosphate transporter, low-affinity (NCBI) | compare |
| b0014 | dnaK | -0.6 | -2.4 | molecular chaperone DnaK (NCBI) | compare |
| b1126 | potA | -0.6 | -3.2 | putrescine/spermidine ABC transporter ATPase protein (NCBI) | compare |
| b2807 | ygdD | -0.6 | -3.1 | conserved inner membrane protein (NCBI) | compare |
| b2567 | rnc | -0.6 | -0.3 | ribonuclease III (NCBI) | compare |
| b2822 | recC | -0.6 | -3.5 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b1258 | yciF | -0.6 | -0.7 | hypothetical protein (NCBI) | compare |
| b4462 | ygaQ | -0.6 | -1.5 | hypothetical protein (RefSeq) | compare |
| b1231 | tyrT | -0.6 | -1.1 | tRNA-Tyr (NCBI) | compare |
| b1942 | fliJ | -0.6 | -1.2 | flagellar biosynthesis chaperone (NCBI) | compare |
| b1104 | ycfL | -0.6 | -1.1 | hypothetical protein (NCBI) | compare |
| b0738 | tolR | -0.5 | -1.0 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0500 | ybbD | -0.5 | -0.3 | hypothetical protein (RefSeq) | compare |
| b2498 | upp | -0.5 | -1.7 | uracil phosphoribosyltransferase (VIMSS) | compare |
| b1728 | ydjM | -0.5 | -3.0 | predicted inner membrane protein regulated by LexA (RefSeq) | compare |
| b1754 | b1754 | -0.5 | -2.2 | orf, hypothetical protein (VIMSS) | compare |
| b3404 | envZ | -0.5 | -4.2 | osmolarity sensor protein (NCBI) | compare |
| b1270 | btuR | -0.5 | -2.1 | cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) | compare |
| b2104 | thiM | -0.5 | -2.0 | hydroxyethylthiazole kinase (NCBI) | compare |
| b4178 | yjeB | -0.5 | -3.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1279 | yciS | -0.5 | -1.2 | conserved inner membrane protein (NCBI) | compare |
| b3778 | rep | -0.5 | -4.0 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b3387 | dam | -0.5 | -4.4 | DNA adenine methylase (NCBI) | compare |
| b0890 | ftsK | -0.5 | -2.1 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b4255 | yjgD | -0.5 | -3.8 | hypothetical protein (NCBI) | compare |
| b2012 | yeeD | -0.5 | -2.6 | hypothetical protein (NCBI) | compare |
| b1804 | rnd | -0.5 | -2.9 | ribonuclease D (NCBI) | compare |
| b2055 | wcaE | -0.5 | -0.3 | predicted glycosyl transferase (NCBI) | compare |
| b1607 | ydgC | -0.5 | -1.4 | conserved inner membrane protein associated with alginate biosynthesis (NCBI) | compare |
| b0049 | apaH | -0.5 | -1.4 | diadenosinetetraphosphatase (NCBI) | compare |
| b3119 | tdcR | -0.5 | -1.7 | threonine dehydratase operon activator protein (VIMSS) | compare |
| b3052 | rfaE | -0.5 | -2.3 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3388 | damX | -0.5 | -4.5 | hypothetical protein (NCBI) | compare |
| b0740 | tolB | -0.5 | -1.6 | translocation protein TolB precursor (NCBI) | compare |
| b1001 | yccE | -0.5 | -0.2 | hypothetical protein (NCBI) | compare |
| b1499 | ydeO | -0.5 | -0.2 | predicted DNA-binding transcriptional acfivator (NCBI) | compare |
| b2501 | ppk | -0.5 | -4.0 | polyphosphate kinase (NCBI) | compare |
| b2704 | srlB | -0.5 | -2.3 | glucitol/sorbitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b3199 | yrbK | -0.5 | -1.6 | hypothetical protein (NCBI) | compare |
| b1536 | ydeI | -0.5 | -0.7 | hypothetical protein (NCBI) | compare |
| b0200 | gmhB | -0.5 | -0.9 | hypothetical protein (NCBI) | compare |
| b2954 | yggV | -0.5 | -2.9 | putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) | compare |
| b1830 | prc | -0.5 | -2.9 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b1600 | mdtJ | -0.5 | -1.2 | multidrug efflux system transporter (NCBI) | compare |
| b3389 | aroB | -0.5 | -4.0 | 3-dehydroquinate synthase (NCBI) | compare |
| b2625 | yfjI | -0.5 | -1.2 | CP4-57 prophage; predicted protein (NCBI) | compare |
| b1819 | manZ | -0.5 | -2.4 | mannose-specific enzyme IID component of PTS (NCBI) | compare |
| b1814 | sdaA | -0.5 | -2.9 | L-serine deaminase I (NCBI) | compare |
| b1262 | trpC | -0.5 | -2.6 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b2569 | lepA | -0.5 | -2.4 | GTP-binding protein LepA (NCBI) | compare |
| b1278 | pgpB | -0.5 | -2.2 | phosphatidylglycerophosphatase B (NCBI) | compare |
| b3813 | uvrD | -0.4 | -4.0 | DNA-dependent ATPase I and helicase II (NCBI) | compare |
| b3183 | obgE | -0.4 | -0.8 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b1522 | yneF | -0.4 | -3.4 | predicted diguanylate cyclase (NCBI) | compare |
| b3609 | secB | -0.4 | -2.5 | export protein SecB (NCBI) | compare |
| b2017 | yefM | -0.4 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b1576 | ydfD | -0.4 | -0.2 | Qin prophage; predicted protein (NCBI) | compare |
| b3017 | sufI | -0.4 | -4.0 | repressor protein for FtsI (NCBI) | compare |
| b1269 | rluB | -0.4 | -2.2 | 23S rRNA pseudouridylate synthase (NCBI) | compare |
| b1286 | rnb | -0.4 | -1.4 | exoribonuclease II (NCBI) | compare |
| b3281 | aroE | -0.4 | -3.9 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b4589 | ylcI | -0.4 | -1.7 | hypothetical protein (RefSeq) | compare |
| b1818 | manY | -0.4 | -1.6 | mannose-specific enzyme IIC component of PTS (NCBI) | compare |
| b1505 | ydeT | -0.4 | -0.9 | hypothetical protein (RefSeq) | compare |
| b2393 | nupC | -0.4 | -2.7 | nucleoside (except guanosine) transporter (NCBI) | compare |
| b2812 | ygdL | -0.4 | -3.1 | hypothetical protein (NCBI) | compare |
| b0222 | lpcA | -0.4 | -1.3 | phosphoheptose isomerase (NCBI) | compare |
| b0827 | moeA | -0.4 | -2.2 | molybdopterin biosynthesis protein (NCBI) | compare |
| b1222 | narX | -0.4 | -2.3 | sensory histidine kinase in two-component regulatory system with NarL (NCBI) | compare |
| b4048 | yjbM | -0.4 | -1.0 | hypothetical protein (NCBI) | compare |
| b0357 | yaiN | -0.4 | -1.5 | putative alpha helix chain (VIMSS) | compare |
| b0970 | yccA | -0.4 | -2.1 | inner membrane protein (NCBI) | compare |
| b0438 | clpX | -0.4 | -2.5 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b1370 | insH-5 | -0.4 | -1.8 | Rac prophage; IS5 transposase and trans-activator (NCBI) | compare |
| b2479 | gcvR | -0.4 | -2.4 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b0784 | moaD | -0.4 | -2.2 | molybdopterin synthase, small subunit (NCBI) | compare |
| b3761 | trpT | -0.4 | -1.2 | tRNA-Trp (NCBI) | compare |
| b1167 | ymgC | -0.4 | -0.2 | hypothetical protein (NCBI) | compare |
| b3238 | yhcN | -0.4 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b0989 | cspH | -0.4 | -1.5 | stress protein, member of the CspA-family (NCBI) | compare |
| b3811 | xerC | -0.4 | -0.6 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b1253 | yciA | -0.4 | -2.0 | predicted hydrolase (NCBI) | compare |
| b1992 | cobS | -0.4 | -1.6 | cobalamin synthase (NCBI) | compare |
| b1628 | rsxB | -0.4 | -1.8 | electron transport complex protein RnfB (NCBI) | compare |
| b0683 | fur | -0.4 | -0.9 | ferric uptake regulator (NCBI) | compare |
| b3933 | ftsN | -0.4 | -3.0 | essential cell division protein (NCBI) | compare |
| b1103 | ycfF | -0.4 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b1255 | yciC | -0.4 | -1.9 | hypothetical protein (NCBI) | compare |
| b1040 | csgD | -0.4 | -0.8 | DNA-binding transcriptional activator in two-component regulatory system (NCBI) | compare |
| b3631 | rfaG | -0.4 | -3.5 | glucosyltransferase I (NCBI) | compare |
| b1563 | relE | -0.4 | -1.3 | Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) | compare |
| b1221 | narL | -0.4 | -2.3 | DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) (NCBI) | compare |
| b2910 | zapA | -0.4 | -2.2 | protein that localizes to the cytokinetic ring (NCBI) | compare |
| b4685 | yrbN | -0.4 | -1.4 | expressed protein (RefSeq) | compare |
| b4191 | ulaR | -0.4 | -2.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3620 | rfaF | -0.4 | -2.4 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b0706 | ybfD | -0.4 | -1.0 | hypothetical protein (NCBI) | compare |
| b1025 | ycdT | -0.4 | -0.9 | predicted diguanylate cyclase (NCBI) | compare |
| b3107 | yhaL | -0.4 | -1.1 | orf, hypothetical protein (VIMSS) | compare |
| b2652 | ileY | -0.4 | -0.5 | tRNA-Ile (NCBI) | compare |
| b0948 | ycbY | -0.4 | -2.9 | predicted methyltransferase (NCBI) | compare |
| b2564 | pdxJ | -0.4 | -1.8 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |