Experiment set42IT050 for Escherichia coli BW25113

Compare to:

LB Time9hr

200 most important genes:

  gene name fitness t score description  
b4053 alr -7.2 -12.1 alanine racemase (NCBI) compare
b4041 plsB -6.0 -3.8 glycerol-3-phosphate acyltransferase (VIMSS) compare
b4237 nrdG -5.7 -3.9 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -4.5 -12.9 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b1850 eda -4.3 -5.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b4025 pgi -3.9 -14.1 glucose-6-phosphate isomerase (NCBI) compare
b1334 fnr -3.1 -3.0 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0386 proC -2.3 -5.8 pyrroline-5-carboxylate reductase (NCBI) compare
b0949 uup -2.1 -11.7 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4593 ymgI -2.0 -1.8 hypothetical protein (RefSeq) compare
b3781 trxA -1.8 -6.5 thioredoxin 1 (VIMSS) compare
b0902 pflA -1.6 -6.6 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b4202 rpsR -1.6 -2.2 30S ribosomal protein S18 (NCBI) compare
b4177 purA -1.5 -2.1 adenylosuccinate synthetase (NCBI) compare
b1123 potD -1.5 -6.9 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b0243 proA -1.5 -8.9 gamma-glutamyl phosphate reductase (NCBI) compare
b1236 galU -1.4 -5.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0990 cspG -1.4 -2.2 DNA-binding transcriptional regulator (NCBI) compare
b1126 potA -1.3 -6.4 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b1124 potC -1.3 -7.5 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b0049 apaH -1.3 -2.5 diadenosinetetraphosphatase (NCBI) compare
b4647 mokA -1.3 -1.4 no description compare
b0014 dnaK -1.2 -3.4 molecular chaperone DnaK (NCBI) compare
b3916 pfkA -1.2 -2.9 6-phosphofructokinase (NCBI) compare
b1125 potB -1.2 -6.0 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b1860 ruvB -1.2 -1.3 Holliday junction DNA helicase B (NCBI) compare
b0242 proB -1.2 -5.2 gamma-glutamyl kinase (NCBI) compare
b0739 tolA -1.1 -2.5 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3868 glnG -1.1 -6.6 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b1049 mdoH -1.1 -7.6 glucosyltransferase MdoH (NCBI) compare
b1048 mdoG -1.1 -5.8 glucan biosynthesis protein, periplasmic (NCBI) compare
b2912 ygfA -1.1 -2.7 putative ligase (VIMSS) compare
b3619 rfaD -1.1 -3.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0142 folK -1.1 -0.8 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1863 ruvC -1.1 -1.8 Holliday junction resolvase (NCBI) compare
b1551 b1551 -1.0 -0.6 orf, hypothetical protein (VIMSS) compare
b2297 pta -1.0 -0.7 phosphate acetyltransferase (NCBI) compare
b2576 srmB -1.0 -3.6 ATP-dependent RNA helicase (NCBI) compare
b3621 rfaC -1.0 -4.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2330 yfcB -1.0 -1.2 putative adenine-specific methylase (VIMSS) compare
b3389 aroB -1.0 -7.9 3-dehydroquinate synthase (NCBI) compare
b2659 b2659 -1.0 -3.1 orf, hypothetical protein (VIMSS) compare
b4535 yniD -1.0 -2.0 predicted protein (RefSeq) compare
b0564 appY -1.0 -1.7 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b0737 tolQ -0.9 -1.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0738 tolR -0.9 -1.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2329 aroC -0.9 -5.0 chorismate synthase (NCBI) compare
b0912 ihfB -0.9 -2.1 integration host factor subunit beta (NCBI) compare
b3281 aroE -0.9 -7.9 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b0903 pflB -0.9 -7.1 pyruvate formate lyase I (NCBI) compare
b3162 deaD -0.9 -4.0 inducible ATP-independent RNA helicase (VIMSS) compare
b0908 aroA -0.9 -5.7 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b0890 ftsK -0.8 -2.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1192 ldcA -0.8 -1.6 L,D-carboxypeptidase A (NCBI) compare
b0145 dksA -0.8 -2.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b0053 surA -0.8 -5.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1347 ydaC -0.8 -0.5 Rac prophage; predicted protein (NCBI) compare
b1231 tyrT -0.8 -1.4 tRNA-Tyr (NCBI) compare
b3493 pitA -0.8 -5.3 phosphate transporter, low-affinity (NCBI) compare
b4676 yoaK -0.8 -0.6 expressed protein (RefSeq) compare
b3052 rfaE -0.8 -3.6 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b2479 gcvR -0.8 -4.5 transcriptional regulation of gcv operon (VIMSS) compare
b2352 yfdI -0.8 -0.8 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b3741 gidA -0.8 -2.2 glucose-inhibited division protein A (NCBI) compare
b0957 ompA -0.8 -3.6 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3035 tolC -0.7 -3.0 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3631 rfaG -0.7 -6.6 glucosyltransferase I (NCBI) compare
b3839 tatC -0.7 -3.9 TatABCE protein translocation system subunit (NCBI) compare
b1693 aroD -0.7 -3.5 3-dehydroquinate dehydratase (NCBI) compare
b2501 ppk -0.7 -5.4 polyphosphate kinase (NCBI) compare
b4375 prfC -0.7 -1.8 peptide chain release factor 3 (NCBI) compare
b2343 b2343 -0.7 -2.3 orf, hypothetical protein (VIMSS) compare
b2620 smpB -0.7 -0.8 SsrA-binding protein (NCBI) compare
b0603 ybdO -0.7 -0.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3229 sspA -0.7 -1.7 stringent starvation protein A (NCBI) compare
b1712 ihfA -0.7 -0.7 integration host factor subunit alpha (NCBI) compare
b0234 yafP -0.7 -1.5 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b0688 pgm -0.7 -2.3 phosphoglucomutase (NCBI) compare
b4702 mgtL -0.7 -1.9 regulatory leader peptide for mgtA (NCBI) compare
b3706 trmE -0.7 -2.4 tRNA modification GTPase (NCBI) compare
b3842 rfaH -0.7 -3.0 transcriptional activator RfaH (NCBI) compare
b2642 yfjW -0.7 -1.1 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2830 nudH -0.7 -1.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b1563 relE -0.7 -1.4 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b2553 glnB -0.7 -3.3 regulatory protein P-II for glutamine synthetase (NCBI) compare
b3620 rfaF -0.6 -3.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2820 recB -0.6 -0.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0740 tolB -0.6 -1.8 translocation protein TolB precursor (NCBI) compare
b1130 phoP -0.6 -1.0 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2894 xerD -0.6 -0.5 site-specific tyrosine recombinase XerD (NCBI) compare
b0222 lpcA -0.6 -1.6 phosphoheptose isomerase (NCBI) compare
b1497 b1497 -0.6 -0.4 putative enzyme (VIMSS) compare
b1001 yccE -0.6 -0.3 hypothetical protein (NCBI) compare
b0237 pepD -0.6 -4.7 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b3630 rfaP -0.6 -4.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1514 lsrC -0.6 -2.2 AI2 transporter (NCBI) compare
b2055 wcaE -0.6 -0.3 predicted glycosyl transferase (NCBI) compare
b3930 menA -0.6 -5.2 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b2083 yegZ -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b1167 ymgC -0.6 -0.3 hypothetical protein (NCBI) compare
b2071 yegJ -0.6 -1.7 hypothetical protein (NCBI) compare
b1235 rssB -0.6 -4.1 response regulator of RpoS (NCBI) compare
b2683 ygaH -0.6 -3.6 predicted inner membrane protein (NCBI) compare
b3405 ompR -0.6 -2.6 osmolarity response regulator (NCBI) compare
b0500 ybbD -0.6 -0.3 hypothetical protein (RefSeq) compare
b3115 tdcD -0.6 -5.4 propionate kinase/acetate kinase C, anaerobic (RefSeq) compare
b1187 fadR -0.6 -2.3 fatty acid metabolism regulator (NCBI) compare
b3390 aroK -0.6 -1.3 shikimate kinase I (NCBI) compare
b0303 ykgI -0.6 -0.7 orf, hypothetical protein (VIMSS) compare
b2258 b2258 -0.6 -1.2 putative transport/receptor protein (VIMSS) compare
b0279 yagM -0.6 -0.3 CP4-6 prophage; predicted protein (NCBI) compare
b0439 lon -0.6 -2.2 DNA-binding ATP-dependent protease La (NCBI) compare
b2528 iscA -0.6 -1.3 iron-sulfur cluster assembly protein (NCBI) compare
b1865 nudB -0.6 -1.1 dATP pyrophosphohydrolase (NCBI) compare
b3387 dam -0.6 -4.6 DNA adenine methylase (NCBI) compare
b2081 yegQ -0.6 -4.0 predicted peptidase (NCBI) compare
b2569 lepA -0.6 -2.5 GTP-binding protein LepA (NCBI) compare
b0948 ycbY -0.6 -3.3 predicted methyltransferase (NCBI) compare
b4066 yjcF -0.6 -0.5 hypothetical protein (NCBI) compare
b1942 fliJ -0.6 -1.5 flagellar biosynthesis chaperone (NCBI) compare
b1505 ydeT -0.5 -1.0 hypothetical protein (RefSeq) compare
b1819 manZ -0.5 -2.1 mannose-specific enzyme IID component of PTS (NCBI) compare
b2114 metG -0.5 -2.1 methionyl-tRNA synthetase (NCBI) compare
b4179 vacB -0.5 -3.6 putative enzyme (VIMSS) compare
b1257 yciE -0.5 -0.3 hypothetical protein (NCBI) compare
b1576 ydfD -0.5 -0.3 Qin prophage; predicted protein (NCBI) compare
b1499 ydeO -0.5 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b4131 cadA -0.5 -4.9 lysine decarboxylase 1 (NCBI) compare
b1593 b1593 -0.5 -2.4 orf, hypothetical protein (VIMSS) compare
b0438 clpX -0.5 -3.0 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0437 clpP -0.5 -2.8 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b4570 lomR -0.5 -1.8 no description compare
b1855 lpxM -0.5 -2.1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0728 sucC -0.5 -3.0 succinyl-CoA synthetase subunit beta (NCBI) compare
b0989 cspH -0.5 -1.5 stress protein, member of the CspA-family (NCBI) compare
b3075 ebgR -0.5 -2.3 DNA-binding transcriptional repressor (NCBI) compare
b4453 ldrD -0.5 -2.3 toxic polypeptide, small (NCBI) compare
b4451 ryhB -0.5 -0.8 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1804 rnd -0.5 -2.9 ribonuclease D (NCBI) compare
b0881 clpS -0.5 -1.5 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b4201 priB -0.5 -1.7 primosomal replication protein N (NCBI) compare
b2562 yfhL -0.5 -3.6 predicted 4Fe-4S cluster-containing protein (NCBI) compare
b2450 yffS -0.5 -1.6 CPZ-55 prophage; predicted protein (RefSeq) compare
b0705 ybfL -0.5 -0.3 putative receptor protein (VIMSS) compare
b0232 yafN -0.5 -0.7 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1630 rsxD -0.5 -2.9 electron transport complex protein RnfD (NCBI) compare
b0080 fruR -0.5 -3.2 DNA-binding transcriptional dual regulator (NCBI) compare
b2299 yfcD -0.5 -2.8 predicted NUDIX hydrolase (NCBI) compare
b4132 cadB -0.5 -4.3 predicted lysine/cadaverine transporter (NCBI) compare
b4695 ykgT -0.5 -2.1 no description compare
b4503 yafF -0.5 -0.7 no description compare
b3158 yhbU -0.5 -3.9 predicted peptidase (collagenase-like) (NCBI) compare
b2393 nupC -0.5 -3.6 nucleoside (except guanosine) transporter (NCBI) compare
b1088 yceD -0.5 -2.2 hypothetical protein (NCBI) compare
b3742 mioC -0.5 -3.4 flavodoxin (NCBI) compare
b1241 adhE -0.5 -4.0 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b3609 secB -0.5 -2.4 export protein SecB (NCBI) compare
b4163 glyV -0.5 -1.2 tRNA-Gly (NCBI) compare
b3500 gor -0.5 -1.1 glutathione reductase (NCBI) compare
b0082 mraW -0.5 -1.7 S-adenosyl-methyltransferase (NCBI) compare
b4048 yjbM -0.5 -0.9 hypothetical protein (NCBI) compare
b2418 pdxK -0.5 -2.5 pyridoxine kinase (NCBI) compare
b1874 cutC -0.5 -1.7 copper homeostasis protein (NCBI) compare
b0263 afuB -0.5 -2.3 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b4577 sgrS -0.5 -1.7 small antisense RNA (NCBI) compare
b1677 lpp -0.5 -1.0 murein lipoprotein (NCBI) compare
b3238 yhcN -0.4 -1.8 orf, hypothetical protein (VIMSS) compare
b1777 b1777 -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b1025 ycdT -0.4 -1.1 predicted diguanylate cyclase (NCBI) compare
b3183 obgE -0.4 -0.6 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2017 yefM -0.4 -0.7 orf, hypothetical protein (VIMSS) compare
b1523 yneG -0.4 -1.4 hypothetical protein (NCBI) compare
b4595 yciY -0.4 -1.7 hypothetical protein (RefSeq) compare
b3806 cyaA -0.4 -2.4 adenylate cyclase (NCBI) compare
b2318 truA -0.4 -1.1 tRNA pseudouridine synthase A (NCBI) compare
b3636 rpmG -0.4 -1.3 50S ribosomal protein L33 (NCBI) compare
b0658 ybeX -0.4 -0.4 predicteed ion transport (NCBI) compare
b1627 rsxA -0.4 -1.9 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b2625 yfjI -0.4 -1.0 CP4-57 prophage; predicted protein (NCBI) compare
b1259 yciG -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b3761 trpT -0.4 -1.1 tRNA-Trp (NCBI) compare
b3204 ptsN -0.4 -2.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b3164 pnp -0.4 -1.6 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b4171 miaA -0.4 -1.6 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1853 yebK -0.4 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1217 chaB -0.4 -1.1 cation transport regulator (NCBI) compare
b2822 recC -0.4 -2.5 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4178 yjeB -0.4 -2.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b2007 yeeX -0.4 -1.9 conserved protein (RefSeq) compare
b1814 sdaA -0.4 -1.9 L-serine deaminase I (NCBI) compare
b1690 ydiM -0.4 -1.3 predicted transporter (NCBI) compare
b1058 yceO -0.4 -0.2 hypothetical protein (NCBI) compare
b1108 ycfP -0.4 -1.5 orf, hypothetical protein (VIMSS) compare
b2814 metZ -0.4 -1.0 tRNA-Met (NCBI) compare
b0167 glnD -0.4 -1.7 PII uridylyl-transferase (NCBI) compare
b4443 gcvB -0.4 -0.2 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b1659 ydhB -0.4 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b0149 mrcB -0.4 -3.5 penicillin-binding protein 1b (NCBI) compare
b2947 gshB -0.4 -2.3 glutathione synthetase (NCBI) compare
b1317 ycjU -0.4 -1.5 predicted beta-phosphoglucomutase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments