Experiment set41IT068 for Escherichia coli BW25113

Compare to:

LB Time6hr

200 most important genes:

  gene name fitness t score description  
b4053 alr -7.0 -14.3 alanine racemase (NCBI) compare
b4237 nrdG -5.1 -7.0 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -4.8 -11.6 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b4041 plsB -3.9 -4.9 glycerol-3-phosphate acyltransferase (VIMSS) compare
b1850 eda -3.4 -5.0 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b4025 pgi -3.0 -13.2 glucose-6-phosphate isomerase (NCBI) compare
b1334 fnr -2.9 -3.3 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b2830 nudH -2.6 -2.9 dinucleoside polyphosphate hydrolase (NCBI) compare
b0902 pflA -2.5 -10.6 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b1860 ruvB -2.1 -1.9 Holliday junction DNA helicase B (NCBI) compare
b0949 uup -2.0 -12.0 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0386 proC -2.0 -6.0 pyrroline-5-carboxylate reductase (NCBI) compare
b0243 proA -1.5 -10.2 gamma-glutamyl phosphate reductase (NCBI) compare
b2330 yfcB -1.5 -1.6 putative adenine-specific methylase (VIMSS) compare
b1236 galU -1.4 -5.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2576 srmB -1.3 -4.1 ATP-dependent RNA helicase (NCBI) compare
b3390 aroK -1.3 -2.0 shikimate kinase I (NCBI) compare
b1123 potD -1.3 -7.1 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b3781 trxA -1.3 -5.3 thioredoxin 1 (VIMSS) compare
b0739 tolA -1.3 -2.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2620 smpB -1.3 -1.5 SsrA-binding protein (NCBI) compare
b2329 aroC -1.2 -6.2 chorismate synthase (NCBI) compare
b0222 lpcA -1.2 -3.0 phosphoheptose isomerase (NCBI) compare
b0908 aroA -1.2 -7.8 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b2912 ygfA -1.2 -2.9 putative ligase (VIMSS) compare
b1048 mdoG -1.2 -6.6 glucan biosynthesis protein, periplasmic (NCBI) compare
b0740 tolB -1.1 -2.9 translocation protein TolB precursor (NCBI) compare
b0242 proB -1.1 -4.9 gamma-glutamyl kinase (NCBI) compare
b0912 ihfB -1.1 -2.0 integration host factor subunit beta (NCBI) compare
b1290 sapF -1.1 -2.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1125 potB -1.1 -4.9 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b0903 pflB -1.1 -8.5 pyruvate formate lyase I (NCBI) compare
b0990 cspG -1.1 -1.7 DNA-binding transcriptional regulator (NCBI) compare
b1124 potC -1.1 -6.2 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b2297 pta -1.1 -0.7 phosphate acetyltransferase (NCBI) compare
b3389 aroB -1.1 -8.7 3-dehydroquinate synthase (NCBI) compare
b3916 pfkA -1.0 -2.9 6-phosphofructokinase (NCBI) compare
b1551 b1551 -1.0 -0.6 orf, hypothetical protein (VIMSS) compare
b0737 tolQ -1.0 -2.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3281 aroE -1.0 -9.0 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b0232 yafN -1.0 -1.2 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0014 dnaK -1.0 -3.5 molecular chaperone DnaK (NCBI) compare
b2699 recA -1.0 -0.6 recombinase A (NCBI) compare
b2318 truA -1.0 -2.6 tRNA pseudouridine synthase A (NCBI) compare
b1429 tehA -1.0 -1.4 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1126 potA -0.9 -4.7 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b1049 mdoH -0.9 -7.2 glucosyltransferase MdoH (NCBI) compare
b2081 yegQ -0.9 -6.4 predicted peptidase (NCBI) compare
b3341 rpsG -0.9 -1.8 30S ribosomal protein S7 (NCBI) compare
b0738 tolR -0.9 -1.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3842 rfaH -0.9 -4.5 transcriptional activator RfaH (NCBI) compare
b1231 tyrT -0.9 -1.6 tRNA-Tyr (NCBI) compare
b3868 glnG -0.9 -5.6 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b1693 aroD -0.9 -5.4 3-dehydroquinate dehydratase (NCBI) compare
b2528 iscA -0.9 -1.5 iron-sulfur cluster assembly protein (NCBI) compare
b2659 b2659 -0.9 -3.1 orf, hypothetical protein (VIMSS) compare
b0237 pepD -0.9 -5.9 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b2017 yefM -0.9 -1.1 orf, hypothetical protein (VIMSS) compare
b4178 yjeB -0.9 -5.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0167 glnD -0.8 -3.4 PII uridylyl-transferase (NCBI) compare
b1347 ydaC -0.8 -0.5 Rac prophage; predicted protein (NCBI) compare
b2569 lepA -0.8 -3.7 GTP-binding protein LepA (NCBI) compare
b2642 yfjW -0.8 -1.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3229 sspA -0.8 -1.7 stringent starvation protein A (NCBI) compare
b3493 pitA -0.8 -5.3 phosphate transporter, low-affinity (NCBI) compare
b1685 ydiH -0.8 -2.1 predicted protein (RefSeq) compare
b2168 fruK -0.8 -0.9 1-phosphofructokinase (NCBI) compare
b3405 ompR -0.8 -3.3 osmolarity response regulator (NCBI) compare
b0303 ykgI -0.8 -0.8 orf, hypothetical protein (VIMSS) compare
b3706 trmE -0.8 -2.8 tRNA modification GTPase (NCBI) compare
b3806 cyaA -0.8 -4.3 adenylate cyclase (NCBI) compare
b3977 tyrU -0.8 -0.9 tRNA-Tyr (NCBI) compare
b0603 ybdO -0.8 -0.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b0142 folK -0.7 -0.6 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0437 clpP -0.7 -3.7 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b4179 vacB -0.7 -4.8 putative enzyme (VIMSS) compare
b1159 mcrA -0.7 -1.3 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b4375 prfC -0.7 -1.9 peptide chain release factor 3 (NCBI) compare
b3158 yhbU -0.7 -5.5 predicted peptidase (collagenase-like) (NCBI) compare
b0688 pgm -0.7 -2.5 phosphoglucomutase (NCBI) compare
b2562 yfhL -0.7 -4.9 predicted 4Fe-4S cluster-containing protein (NCBI) compare
b4535 yniD -0.7 -1.3 predicted protein (RefSeq) compare
b1235 rssB -0.7 -5.0 response regulator of RpoS (NCBI) compare
b0049 apaH -0.7 -1.6 diadenosinetetraphosphatase (NCBI) compare
b3863 polA -0.7 -0.8 DNA polymerase I (NCBI) compare
b1351 racC -0.7 -0.4 Rac prophage; predicted protein (NCBI) compare
b3159 yhbV -0.7 -5.5 orf, hypothetical protein (VIMSS) compare
b0438 clpX -0.7 -4.1 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1292 sapC -0.7 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4131 cadA -0.7 -6.1 lysine decarboxylase 1 (NCBI) compare
b3620 rfaF -0.7 -3.7 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0145 dksA -0.6 -1.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1497 b1497 -0.6 -0.4 putative enzyme (VIMSS) compare
b0500 ybbD -0.6 -0.3 hypothetical protein (RefSeq) compare
b0890 ftsK -0.6 -2.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2820 recB -0.6 -0.8 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4191 ulaR -0.6 -3.3 DNA-binding transcriptional dual regulator (NCBI) compare
b1593 b1593 -0.6 -2.6 orf, hypothetical protein (VIMSS) compare
b1253 yciA -0.6 -2.0 predicted hydrolase (NCBI) compare
b3162 deaD -0.6 -2.9 inducible ATP-independent RNA helicase (VIMSS) compare
b3619 rfaD -0.6 -2.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3035 tolC -0.6 -2.5 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3157 yhbT -0.6 -2.7 predicted lipid carrier protein (NCBI) compare
b0080 fruR -0.6 -3.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2055 wcaE -0.6 -0.3 predicted glycosyl transferase (NCBI) compare
b3164 pnp -0.6 -1.9 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b4132 cadB -0.6 -5.4 predicted lysine/cadaverine transporter (NCBI) compare
b0683 fur -0.6 -1.0 ferric uptake regulator (NCBI) compare
b2570 rseC -0.6 -3.9 RseC protein involved in reduction of the SoxR iron-sulfur cluster (NCBI) compare
b2567 rnc -0.6 -0.3 ribonuclease III (NCBI) compare
b4414 tff -0.6 -1.6 unknown RNA (NCBI) compare
b1167 ymgC -0.6 -0.3 hypothetical protein (NCBI) compare
b1257 yciE -0.6 -0.3 hypothetical protein (NCBI) compare
b0082 mraW -0.6 -2.0 S-adenosyl-methyltransferase (NCBI) compare
b0677 nagA -0.6 -2.9 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1536 ydeI -0.6 -0.8 hypothetical protein (NCBI) compare
b2479 gcvR -0.6 -3.0 transcriptional regulation of gcv operon (VIMSS) compare
b2104 thiM -0.6 -2.2 hydroxyethylthiazole kinase (NCBI) compare
b0357 yaiN -0.6 -1.2 putative alpha helix chain (VIMSS) compare
b2894 xerD -0.6 -0.5 site-specific tyrosine recombinase XerD (NCBI) compare
b3052 rfaE -0.6 -2.7 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1690 ydiM -0.6 -1.7 predicted transporter (NCBI) compare
b4402 yjjY -0.6 -0.7 hypothetical protein (NCBI) compare
b1818 manY -0.6 -1.9 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1187 fadR -0.6 -2.3 fatty acid metabolism regulator (NCBI) compare
b1499 ydeO -0.6 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1518 lsrG -0.6 -1.0 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b1863 ruvC -0.5 -1.1 Holliday junction resolvase (NCBI) compare
b0975 hyaD -0.5 -3.1 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b1291 sapD -0.5 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1259 yciG -0.5 -1.8 orf, hypothetical protein (VIMSS) compare
b0741 pal -0.5 -1.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0957 ompA -0.5 -2.7 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4503 yafF -0.5 -0.8 no description compare
b1192 ldcA -0.5 -1.3 L,D-carboxypeptidase A (NCBI) compare
b3630 rfaP -0.5 -4.3 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1576 ydfD -0.5 -0.3 Qin prophage; predicted protein (NCBI) compare
b2553 glnB -0.5 -2.5 regulatory protein P-II for glutamine synthetase (NCBI) compare
b4066 yjcF -0.5 -0.5 hypothetical protein (NCBI) compare
b1363 trkG -0.5 -0.4 Rac prophage; potassium transporter subunit (NCBI) compare
b3811 xerC -0.5 -0.8 site-specific tyrosine recombinase XerC (NCBI) compare
b1284 yciT -0.5 -3.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3500 gor -0.5 -1.3 glutathione reductase (NCBI) compare
b3930 menA -0.5 -4.4 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b4202 rpsR -0.5 -1.0 30S ribosomal protein S18 (NCBI) compare
b0425 panE -0.5 -4.0 2-dehydropantoate 2-reductase (NCBI) compare
b3002 yqhA -0.5 -1.2 hypothetical protein (NCBI) compare
b4702 mgtL -0.5 -1.6 regulatory leader peptide for mgtA (NCBI) compare
b1842 holE -0.5 -1.4 DNA polymerase III, theta subunit (NCBI) compare
b1196 ycgY -0.5 -2.1 hypothetical protein (NCBI) compare
b1862 yebB -0.5 -2.5 orf, hypothetical protein (VIMSS) compare
b1627 rsxA -0.5 -2.2 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b4520 ymgF -0.5 -1.2 hypothetical protein (NCBI) compare
b1589 ynfG -0.5 -1.4 oxidoreductase, Fe-S subunit (NCBI) compare
b2501 ppk -0.5 -3.5 polyphosphate kinase (NCBI) compare
b1412 azoR -0.5 -2.1 acyl carrier protein phosphodiesterase (NCBI) compare
b0018 mokC -0.5 -1.1 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b0948 ycbY -0.5 -3.1 predicted methyltransferase (NCBI) compare
b2704 srlB -0.5 -2.0 glucitol/sorbitol-specific enzyme IIA component of PTS (NCBI) compare
b3742 mioC -0.5 -3.2 flavodoxin (NCBI) compare
b1785 yeaI -0.5 -1.8 predicted diguanylate cyclase (NCBI) compare
b1804 rnd -0.5 -2.8 ribonuclease D (NCBI) compare
b3082 ygjM -0.5 -1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1643 ydhI -0.5 -2.4 predicted inner membrane protein (NCBI) compare
b4593 ymgI -0.5 -0.7 hypothetical protein (RefSeq) compare
b2093 gatB -0.5 -3.0 galactitol-specific enzyme IIB component of PTS (NCBI) compare
b1730 ydjO -0.5 -0.8 predicted protein (RefSeq) compare
b2085 b2085 -0.5 -2.4 orf, hypothetical protein (VIMSS) compare
b3204 ptsN -0.5 -2.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b4443 gcvB -0.5 -0.2 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b4436 ryeC -0.4 -1.2 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b3465 yhhF -0.4 -3.0 predicted methyltransferase (NCBI) compare
b0125 hpt -0.4 -2.4 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b1594 dgsA -0.4 -2.2 DNA-binding transcriptional repressor (NCBI) compare
b1527 yneK -0.4 -1.5 hypothetical protein (NCBI) compare
b3115 tdcD -0.4 -4.2 propionate kinase/acetate kinase C, anaerobic (RefSeq) compare
b1505 ydeT -0.4 -0.9 hypothetical protein (RefSeq) compare
b2597 yfiA -0.4 -1.3 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b0767 ybhE -0.4 -2.2 6-phosphogluconolactonase (NCBI) compare
b2393 nupC -0.4 -3.4 nucleoside (except guanosine) transporter (NCBI) compare
b2080 b2080 -0.4 -1.4 orf, hypothetical protein (VIMSS) compare
b3387 dam -0.4 -3.6 DNA adenine methylase (NCBI) compare
b4133 cadC -0.4 -3.9 DNA-binding transcriptional activator (NCBI) compare
b0436 tig -0.4 -3.1 trigger factor (NCBI) compare
b0053 surA -0.4 -2.8 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0279 yagM -0.4 -0.4 CP4-6 prophage; predicted protein (NCBI) compare
b2319 usg -0.4 -2.0 hypothetical protein (NCBI) compare
b0560 nohB -0.4 -1.3 DLP12 prophage; DNA packaging protein (NCBI) compare
b0200 gmhB -0.4 -0.6 hypothetical protein (NCBI) compare
b4577 sgrS -0.4 -1.8 small antisense RNA (NCBI) compare
b4426 isrA -0.4 -1.8 unknown RNA (NCBI) compare
b0658 ybeX -0.4 -0.5 predicteed ion transport (NCBI) compare
b2853 ygeI -0.4 -0.2 hypothetical protein (NCBI) compare
b2847 yqeI -0.4 -0.3 predicted transcriptional regulator (NCBI) compare
b4676 yoaK -0.4 -0.4 expressed protein (RefSeq) compare
b2735 ygbI -0.4 -2.5 predicted DNA-binding transcriptional regulator (RefSeq) compare
b2498 upp -0.4 -1.3 uracil phosphoribosyltransferase (VIMSS) compare
b3649 rpoZ -0.4 -1.5 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1222 narX -0.4 -2.3 sensory histidine kinase in two-component regulatory system with NarL (NCBI) compare
b3545 proK -0.4 -1.4 tRNA-Pro (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments