Experiment set41IT065 for Escherichia coli BW25113

Compare to:

LB Time4hr

200 most important genes:

  gene name fitness t score description  
b4053 alr -7.8 -10.6 alanine racemase (NCBI) compare
b4237 nrdG -5.0 -8.4 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -4.9 -11.4 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b4041 plsB -4.8 -4.9 glycerol-3-phosphate acyltransferase (VIMSS) compare
b4025 pgi -3.2 -14.1 glucose-6-phosphate isomerase (NCBI) compare
b1334 fnr -2.6 -2.9 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b1850 eda -2.3 -3.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0949 uup -2.3 -12.7 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4202 rpsR -2.0 -2.9 30S ribosomal protein S18 (NCBI) compare
b0902 pflA -1.8 -8.6 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b0243 proA -1.7 -10.2 gamma-glutamyl phosphate reductase (NCBI) compare
b0386 proC -1.7 -5.3 pyrroline-5-carboxylate reductase (NCBI) compare
b4593 ymgI -1.4 -1.6 hypothetical protein (RefSeq) compare
b0242 proB -1.4 -5.8 gamma-glutamyl kinase (NCBI) compare
b3781 trxA -1.4 -6.0 thioredoxin 1 (VIMSS) compare
b2330 yfcB -1.3 -1.2 putative adenine-specific methylase (VIMSS) compare
b3035 tolC -1.3 -4.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2912 ygfA -1.3 -3.0 putative ligase (VIMSS) compare
b2620 smpB -1.2 -1.3 SsrA-binding protein (NCBI) compare
b3916 pfkA -1.2 -3.4 6-phosphofructokinase (NCBI) compare
b1292 sapC -1.2 -2.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4535 yniD -1.2 -1.7 predicted protein (RefSeq) compare
b3930 menA -1.2 -10.0 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b0142 folK -1.2 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1730 ydjO -1.2 -1.4 predicted protein (RefSeq) compare
b0232 yafN -1.1 -1.4 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0200 gmhB -1.1 -1.6 hypothetical protein (NCBI) compare
b2329 aroC -1.0 -6.0 chorismate synthase (NCBI) compare
b0903 pflB -1.0 -7.8 pyruvate formate lyase I (NCBI) compare
b3493 pitA -1.0 -6.7 phosphate transporter, low-affinity (NCBI) compare
b3229 sspA -1.0 -2.4 stringent starvation protein A (NCBI) compare
b2531 iscR -1.0 -2.1 DNA-binding transcriptional repressor (NCBI) compare
b2576 srmB -1.0 -2.8 ATP-dependent RNA helicase (NCBI) compare
b0912 ihfB -1.0 -2.3 integration host factor subunit beta (NCBI) compare
b1123 potD -0.9 -5.8 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b2699 recA -0.9 -0.6 recombinase A (NCBI) compare
b1126 potA -0.9 -5.8 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b4552 yrhC -0.9 -1.4 no description compare
b4191 ulaR -0.9 -3.4 DNA-binding transcriptional dual regulator (NCBI) compare
b4066 yjcF -0.9 -0.6 hypothetical protein (NCBI) compare
b1124 potC -0.9 -5.5 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b0881 clpS -0.9 -2.4 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b2814 metZ -0.9 -2.1 tRNA-Met (NCBI) compare
b1125 potB -0.9 -3.9 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b3868 glnG -0.9 -5.5 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b4402 yjjY -0.9 -1.1 hypothetical protein (NCBI) compare
b2297 pta -0.9 -0.5 phosphate acetyltransferase (NCBI) compare
b2659 b2659 -0.9 -2.7 orf, hypothetical protein (VIMSS) compare
b3405 ompR -0.8 -2.8 osmolarity response regulator (NCBI) compare
b3390 aroK -0.8 -1.9 shikimate kinase I (NCBI) compare
b0237 pepD -0.8 -6.3 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1493 gadB -0.8 -1.3 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b4177 purA -0.8 -1.8 adenylosuccinate synthetase (NCBI) compare
b1049 mdoH -0.8 -5.9 glucosyltransferase MdoH (NCBI) compare
b3183 obgE -0.8 -1.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0303 ykgI -0.8 -0.8 orf, hypothetical protein (VIMSS) compare
b0706 ybfD -0.8 -2.6 hypothetical protein (NCBI) compare
b2569 lepA -0.7 -3.5 GTP-binding protein LepA (NCBI) compare
b1551 b1551 -0.7 -0.5 orf, hypothetical protein (VIMSS) compare
b2081 yegQ -0.7 -5.7 predicted peptidase (NCBI) compare
b3082 ygjM -0.7 -1.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b3636 rpmG -0.7 -2.0 50S ribosomal protein L33 (NCBI) compare
b0908 aroA -0.7 -5.0 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b3389 aroB -0.7 -5.5 3-dehydroquinate synthase (NCBI) compare
b2017 yefM -0.7 -1.0 orf, hypothetical protein (VIMSS) compare
b2553 glnB -0.7 -2.7 regulatory protein P-II for glutamine synthetase (NCBI) compare
b2894 xerD -0.7 -0.6 site-specific tyrosine recombinase XerD (NCBI) compare
b0082 mraW -0.7 -2.5 S-adenosyl-methyltransferase (NCBI) compare
b1358 ydaT -0.7 -1.9 Rac prophage; predicted protein (NCBI) compare
b0740 tolB -0.7 -1.8 translocation protein TolB precursor (NCBI) compare
b0965 b0965 -0.7 -3.2 orf, hypothetical protein (VIMSS) compare
b4171 miaA -0.7 -2.6 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b0564 appY -0.7 -1.4 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1882 cheY -0.7 -0.6 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0741 pal -0.7 -2.0 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b4375 prfC -0.7 -1.9 peptide chain release factor 3 (NCBI) compare
b0989 cspH -0.7 -2.1 stress protein, member of the CspA-family (NCBI) compare
b1754 b1754 -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b1293 sapB -0.6 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0167 glnD -0.6 -2.9 PII uridylyl-transferase (NCBI) compare
b1171 b1171 -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b1758 b1758 -0.6 -1.3 putative cytochrome oxidase (VIMSS) compare
b3281 aroE -0.6 -5.6 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1235 rssB -0.6 -4.1 response regulator of RpoS (NCBI) compare
b2479 gcvR -0.6 -3.5 transcriptional regulation of gcv operon (VIMSS) compare
b1048 mdoG -0.6 -3.2 glucan biosynthesis protein, periplasmic (NCBI) compare
b3806 cyaA -0.6 -3.6 adenylate cyclase (NCBI) compare
b0948 ycbY -0.6 -3.6 predicted methyltransferase (NCBI) compare
b0705 ybfL -0.6 -0.3 putative receptor protein (VIMSS) compare
b0990 cspG -0.6 -1.1 DNA-binding transcriptional regulator (NCBI) compare
b1290 sapF -0.6 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3115 tdcD -0.6 -5.5 propionate kinase/acetate kinase C, anaerobic (RefSeq) compare
b3839 tatC -0.6 -3.4 TatABCE protein translocation system subunit (NCBI) compare
b0729 sucD -0.6 -3.0 succinyl-CoA synthetase subunit alpha (NCBI) compare
b0438 clpX -0.6 -3.8 ATP-dependent protease ATP-binding subunit (NCBI) compare
b4131 cadA -0.6 -5.4 lysine decarboxylase 1 (NCBI) compare
b1253 yciA -0.6 -1.9 predicted hydrolase (NCBI) compare
b0677 nagA -0.6 -3.0 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0437 clpP -0.6 -3.3 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b2343 b2343 -0.6 -2.1 orf, hypothetical protein (VIMSS) compare
b1692 ydiB -0.6 -2.3 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b2114 metG -0.6 -2.2 methionyl-tRNA synthetase (NCBI) compare
b1540 ydfH -0.6 -1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b2830 nudH -0.6 -0.9 dinucleoside polyphosphate hydrolase (NCBI) compare
b4414 tff -0.6 -1.9 unknown RNA (NCBI) compare
b0234 yafP -0.6 -1.3 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b1648 b1648 -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b2808 gcvA -0.6 -2.4 DNA-binding transcriptional dual regulator (NCBI) compare
b0737 tolQ -0.5 -1.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1187 fadR -0.5 -2.0 fatty acid metabolism regulator (NCBI) compare
b4178 yjeB -0.5 -3.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1992 cobS -0.5 -1.7 cobalamin synthase (NCBI) compare
b0728 sucC -0.5 -3.1 succinyl-CoA synthetase subunit beta (NCBI) compare
b1347 ydaC -0.5 -0.3 Rac prophage; predicted protein (NCBI) compare
b0088 murD -0.5 -1.6 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1594 dgsA -0.5 -2.1 DNA-binding transcriptional repressor (NCBI) compare
b0500 ybbD -0.5 -0.3 hypothetical protein (RefSeq) compare
b1712 ihfA -0.5 -0.5 integration host factor subunit alpha (NCBI) compare
b0890 ftsK -0.5 -1.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2528 iscA -0.5 -1.3 iron-sulfur cluster assembly protein (NCBI) compare
b4702 mgtL -0.5 -1.6 regulatory leader peptide for mgtA (NCBI) compare
b3443 yrhA -0.5 -1.4 orf, hypothetical protein (VIMSS) compare
b4179 vacB -0.5 -3.3 putative enzyme (VIMSS) compare
b2652 ileY -0.5 -0.6 tRNA-Ile (NCBI) compare
b0739 tolA -0.5 -1.3 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3257 yhdT -0.5 -3.4 conserved inner membrane protein (NCBI) compare
b4048 yjbM -0.5 -1.1 hypothetical protein (NCBI) compare
b1583 ynfB -0.5 -1.5 hypothetical protein (NCBI) compare
b3706 trmE -0.5 -2.0 tRNA modification GTPase (NCBI) compare
b0125 hpt -0.5 -2.5 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b1522 yneF -0.5 -2.3 predicted diguanylate cyclase (NCBI) compare
b2498 upp -0.5 -1.5 uracil phosphoribosyltransferase (VIMSS) compare
b0014 dnaK -0.5 -1.8 molecular chaperone DnaK (NCBI) compare
b0439 lon -0.5 -2.0 DNA-binding ATP-dependent protease La (NCBI) compare
b2567 rnc -0.5 -0.2 ribonuclease III (NCBI) compare
b1241 adhE -0.5 -3.8 fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) compare
b0685 ybfE -0.5 -2.2 orf, hypothetical protein (VIMSS) compare
b2110 yehC -0.5 -1.0 predicted periplasmic pilin chaperone (NCBI) compare
b3619 rfaD -0.5 -1.8 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b4138 dcuA -0.5 -4.1 C4-dicarboxylate antiporter (NCBI) compare
b3884 yihW -0.5 -3.0 putative DEOR-type transcriptional regulator (VIMSS) compare
b3741 gidA -0.5 -1.6 glucose-inhibited division protein A (NCBI) compare
b3210 arcB -0.5 -3.0 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b2136 yohD -0.5 -2.1 orf, hypothetical protein (VIMSS) compare
b1259 yciG -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b1727 yniC -0.4 -1.6 predicted hydrolase (NCBI) compare
b1582 ynfA -0.4 -1.6 hypothetical protein (NCBI) compare
b0357 yaiN -0.4 -1.6 putative alpha helix chain (VIMSS) compare
b1593 b1593 -0.4 -2.3 orf, hypothetical protein (VIMSS) compare
b3159 yhbV -0.4 -3.6 orf, hypothetical protein (VIMSS) compare
b2141 yohJ -0.4 -1.4 hypothetical protein (NCBI) compare
b1236 galU -0.4 -1.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2562 yfhL -0.4 -3.3 predicted 4Fe-4S cluster-containing protein (NCBI) compare
b0957 ompA -0.4 -2.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b0603 ybdO -0.4 -0.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1865 nudB -0.4 -1.0 dATP pyrophosphohydrolase (NCBI) compare
b3158 yhbU -0.4 -3.0 predicted peptidase (collagenase-like) (NCBI) compare
b4132 cadB -0.4 -3.9 predicted lysine/cadaverine transporter (NCBI) compare
b1814 sdaA -0.4 -1.8 L-serine deaminase I (NCBI) compare
b0080 fruR -0.4 -2.5 DNA-binding transcriptional dual regulator (NCBI) compare
b2024 hisA -0.4 -1.8 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b1693 aroD -0.4 -2.3 3-dehydroquinate dehydratase (NCBI) compare
b2735 ygbI -0.4 -2.3 predicted DNA-binding transcriptional regulator (RefSeq) compare
b3935 priA -0.4 -1.3 primosome assembly protein PriA (NCBI) compare
b2285 nuoE -0.4 -1.0 NADH dehydrogenase subunit E (NCBI) compare
b2363 yfdT -0.4 -1.6 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2318 truA -0.4 -1.4 tRNA pseudouridine synthase A (NCBI) compare
b4438 cyaR -0.4 -1.9 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b3180 yhbY -0.4 -2.3 predicted RNA-binding protein (NCBI) compare
b2501 ppk -0.4 -2.9 polyphosphate kinase (NCBI) compare
b1222 narX -0.4 -2.3 sensory histidine kinase in two-component regulatory system with NarL (NCBI) compare
b3497 yhiQ -0.4 -3.0 predicted SAM-dependent methyltransferase (NCBI) compare
b1465 narV -0.4 -1.8 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b3409 feoB -0.4 -3.8 ferrous iron transport protein B (NCBI) compare
b4509 ylcG -0.4 -1.0 DLP12 prophage; predicted protein (NCBI) compare
b0676 nagC -0.4 -3.1 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) compare
b2820 recB -0.4 -0.6 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0247 ykfG -0.4 -1.0 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b2101 yegW -0.4 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b0688 pgm -0.4 -1.4 phosphoglucomutase (NCBI) compare
b4255 yjgD -0.4 -1.8 hypothetical protein (NCBI) compare
b1595 ynfL -0.4 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1853 yebK -0.4 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b0738 tolR -0.4 -0.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3408 feoA -0.4 -3.4 ferrous iron transport protein A (NCBI) compare
b1104 ycfL -0.4 -0.7 hypothetical protein (NCBI) compare
b4443 gcvB -0.4 -0.2 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b3149 yraO -0.4 -2.9 DnaA initiator-associating factor for replication initiation (NCBI) compare
b1516 lsrB -0.4 -2.3 AI2 transporter (NCBI) compare
b1278 pgpB -0.4 -1.0 phosphatidylglycerophosphatase B (NCBI) compare
b2079 baeR -0.4 -2.9 DNA-binding response regulator in two-component regulatory system with BaeS (NCBI) compare
b1161 ycgX -0.4 -0.6 hypothetical protein (NCBI) compare
b0145 dksA -0.4 -1.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1148 ymfM -0.4 -1.8 e14 prophage; predicted protein (NCBI) compare
b4501 torI -0.4 -2.4 response regulator inhibitor for tor operon (NCBI) compare
b2754 ygbF -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b3204 ptsN -0.4 -2.2 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2918 argK -0.4 -2.3 arginine/ornithine transport system ATPase (NCBI) compare
b0506 allR -0.4 -2.4 DNA-binding transcriptional repressor (NCBI) compare
b3162 deaD -0.4 -1.8 inducible ATP-independent RNA helicase (VIMSS) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments