Experiment set41IT062 for Escherichia coli BW25113

Compare to:

LB Time1hr

200 most important genes:

  gene name fitness t score description  
b4053 alr -4.5 -16.7 alanine racemase (NCBI) compare
b4237 nrdG -4.4 -10.9 anaerobic ribonucleotide reductase activating protein (NCBI) compare
b4238 nrdD -3.9 -16.8 anaerobic ribonucleoside triphosphate reductase (NCBI) compare
b4041 plsB -3.3 -6.0 glycerol-3-phosphate acyltransferase (VIMSS) compare
b0386 proC -3.0 -6.2 pyrroline-5-carboxylate reductase (NCBI) compare
b2912 ygfA -2.2 -3.5 putative ligase (VIMSS) compare
b0949 uup -2.0 -11.5 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4535 yniD -1.8 -2.2 predicted protein (RefSeq) compare
b1334 fnr -1.7 -2.0 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0200 gmhB -1.5 -1.9 hypothetical protein (NCBI) compare
b1429 tehA -1.3 -1.8 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b0243 proA -1.3 -9.0 gamma-glutamyl phosphate reductase (NCBI) compare
b3035 tolC -1.3 -5.2 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b2830 nudH -1.3 -1.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b1850 eda -1.2 -2.7 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1860 ruvB -1.2 -1.1 Holliday junction DNA helicase B (NCBI) compare
b0049 apaH -1.2 -2.6 diadenosinetetraphosphatase (NCBI) compare
b0902 pflA -1.2 -4.8 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b0242 proB -1.1 -6.9 gamma-glutamyl kinase (NCBI) compare
b2168 fruK -1.1 -1.5 1-phosphofructokinase (NCBI) compare
b2846 yqeH -1.1 -0.8 orf, hypothetical protein (VIMSS) compare
b1346 ydaQ -1.0 -1.9 orf, hypothetical protein (VIMSS) compare
b0142 folK -1.0 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1863 ruvC -1.0 -1.3 Holliday junction resolvase (NCBI) compare
b3162 deaD -1.0 -4.6 inducible ATP-independent RNA helicase (VIMSS) compare
b2450 yffS -0.9 -3.0 CPZ-55 prophage; predicted protein (RefSeq) compare
b4402 yjjY -0.9 -1.2 hypothetical protein (NCBI) compare
b1677 lpp -0.9 -2.2 murein lipoprotein (NCBI) compare
b4647 mokA -0.8 -1.2 no description compare
b0903 pflB -0.8 -6.1 pyruvate formate lyase I (NCBI) compare
b3229 sspA -0.8 -2.2 stringent starvation protein A (NCBI) compare
b1290 sapF -0.8 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0741 pal -0.8 -2.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0739 tolA -0.7 -1.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1765 ydjA -0.7 -0.8 predicted oxidoreductase (NCBI) compare
b4593 ymgI -0.7 -0.9 hypothetical protein (RefSeq) compare
b3839 tatC -0.7 -4.2 TatABCE protein translocation system subunit (NCBI) compare
b4503 yafF -0.7 -1.0 no description compare
b2318 truA -0.7 -2.4 tRNA pseudouridine synthase A (NCBI) compare
b1292 sapC -0.7 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3052 rfaE -0.7 -3.5 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1126 potA -0.7 -4.3 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b0948 ycbY -0.7 -4.2 predicted methyltransferase (NCBI) compare
b0053 surA -0.7 -4.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3405 ompR -0.7 -3.1 osmolarity response regulator (NCBI) compare
b1286 rnb -0.6 -1.7 exoribonuclease II (NCBI) compare
b4171 miaA -0.6 -2.5 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1882 cheY -0.6 -0.5 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0014 dnaK -0.6 -1.8 molecular chaperone DnaK (NCBI) compare
b1360 ydaV -0.6 -1.8 Rac prophage; predicted DNA replication protein (NCBI) compare
b3794 rffM -0.6 -4.3 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3761 trpT -0.6 -1.8 tRNA-Trp (NCBI) compare
b1642 slyA -0.6 -1.7 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b3792 wzxE -0.6 -4.2 O-antigen translocase (NCBI) compare
b2259 pmrD -0.6 -1.2 polymyxin resistance protein B (VIMSS) compare
b3916 pfkA -0.6 -2.1 6-phosphofructokinase (NCBI) compare
b3500 gor -0.6 -1.6 glutathione reductase (NCBI) compare
b4048 yjbM -0.6 -1.3 hypothetical protein (NCBI) compare
b1124 potC -0.6 -3.4 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b1522 yneF -0.6 -2.0 predicted diguanylate cyclase (NCBI) compare
b0303 ykgI -0.6 -0.6 orf, hypothetical protein (VIMSS) compare
b2501 ppk -0.6 -3.9 polyphosphate kinase (NCBI) compare
b1593 b1593 -0.6 -2.7 orf, hypothetical protein (VIMSS) compare
b1438 ydcQ -0.6 -2.9 predicted DNA-binding transcriptional regulator (RefSeq) compare
b4414 tff -0.5 -2.3 unknown RNA (NCBI) compare
b2498 upp -0.5 -1.6 uracil phosphoribosyltransferase (VIMSS) compare
b0564 appY -0.5 -1.1 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3164 pnp -0.5 -2.3 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0232 yafN -0.5 -0.7 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b1862 yebB -0.5 -2.4 orf, hypothetical protein (VIMSS) compare
b1123 potD -0.5 -3.0 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b2325 yfcL -0.5 -2.5 hypothetical protein (NCBI) compare
b0688 pgm -0.5 -1.8 phosphoglucomutase (NCBI) compare
b0471 ybaB -0.5 -2.3 hypothetical protein (NCBI) compare
b2911 ssrS -0.5 -1.5 6S regulatory RNA (NCBI) compare
b1088 yceD -0.5 -2.4 hypothetical protein (NCBI) compare
b2704 srlB -0.5 -2.3 glucitol/sorbitol-specific enzyme IIA component of PTS (NCBI) compare
b1921 fliZ -0.5 -2.3 orf, hypothetical protein (VIMSS) compare
b1104 ycfL -0.5 -1.0 hypothetical protein (NCBI) compare
b3935 priA -0.5 -1.4 primosome assembly protein PriA (NCBI) compare
b0683 fur -0.5 -1.0 ferric uptake regulator (NCBI) compare
b1150 ymfR -0.5 -0.8 e14 prophage; predicted protein (NCBI) compare
b4202 rpsR -0.5 -1.2 30S ribosomal protein S18 (NCBI) compare
b3781 trxA -0.5 -2.7 thioredoxin 1 (VIMSS) compare
b3791 rffA -0.5 -3.7 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3493 pitA -0.5 -3.5 phosphate transporter, low-affinity (NCBI) compare
b2576 srmB -0.5 -1.7 ATP-dependent RNA helicase (NCBI) compare
b0167 glnD -0.5 -2.2 PII uridylyl-transferase (NCBI) compare
b1992 cobS -0.5 -1.2 cobalamin synthase (NCBI) compare
b2659 b2659 -0.5 -2.2 orf, hypothetical protein (VIMSS) compare
b3390 aroK -0.5 -1.4 shikimate kinase I (NCBI) compare
b3619 rfaD -0.5 -2.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1984 asnW -0.5 -0.8 tRNA-Asn (NCBI) compare
b3600 mtlD -0.5 -3.4 mannitol-1-phosphate 5-dehydrogenase (NCBI) compare
b2330 yfcB -0.5 -0.6 putative adenine-specific methylase (VIMSS) compare
b2642 yfjW -0.4 -0.9 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2528 iscA -0.4 -0.9 iron-sulfur cluster assembly protein (NCBI) compare
b2297 pta -0.4 -0.3 phosphate acetyltransferase (NCBI) compare
b1846 yebE -0.4 -2.4 hypothetical protein (NCBI) compare
b1160 elbA -0.4 -0.5 hypothetical protein (NCBI) compare
b0118 acnB -0.4 -0.4 aconitate hydratase (NCBI) compare
b1066 rimJ -0.4 -3.3 ribosomal-protein-S5-alanine N-acetyltransferase (NCBI) compare
b4436 ryeC -0.4 -0.7 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b1685 ydiH -0.4 -1.1 predicted protein (RefSeq) compare
b2424 cysU -0.4 -2.0 sulfate/thiosulfate transporter subunit (NCBI) compare
b4375 prfC -0.4 -1.5 peptide chain release factor 3 (NCBI) compare
b1187 fadR -0.4 -1.9 fatty acid metabolism regulator (NCBI) compare
b3620 rfaF -0.4 -2.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3261 fis -0.4 -0.5 DNA-binding protein Fis (NCBI) compare
b1926 fliT -0.4 -1.5 predicted chaperone (NCBI) compare
b4545 ypdJ -0.4 -1.1 no description compare
b1370 insH-5 -0.4 -1.5 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b1291 sapD -0.4 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1358 ydaT -0.4 -0.6 Rac prophage; predicted protein (NCBI) compare
b1778 yeaA -0.4 -1.4 methionine sulfoxide reductase B (NCBI) compare
b0222 lpcA -0.4 -1.1 phosphoheptose isomerase (NCBI) compare
b4493 gapC -0.4 -1.4 no description compare
b1855 lpxM -0.4 -1.5 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1613 manA -0.4 -1.1 mannose-6-phosphate isomerase (VIMSS) compare
b4655 ythA -0.4 -0.7 expressed protein (RefSeq) compare
b3868 glnG -0.4 -2.9 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b0990 cspG -0.4 -0.8 DNA-binding transcriptional regulator (NCBI) compare
b0247 ykfG -0.4 -1.0 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b0975 hyaD -0.4 -1.9 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b4066 yjcF -0.4 -0.5 hypothetical protein (NCBI) compare
b1125 potB -0.4 -1.2 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b3930 menA -0.4 -3.5 1,4-dihydroxy-2-naphthoate octaprenyltransferase (NCBI) compare
b1271 yciK -0.4 -1.2 short chain dehydrogenase (NCBI) compare
b2021 hisC -0.4 -2.4 histidinol-phosphate aminotransferase (NCBI) compare
b3204 ptsN -0.4 -2.1 sugar-specific enzyme IIA component of PTS (NCBI) compare
b1679 sufE -0.4 -1.1 cysteine desufuration protein SufE (NCBI) compare
b1563 relE -0.4 -1.1 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1675 ydhZ -0.4 -2.3 hypothetical protein (NCBI) compare
b3002 yqhA -0.4 -1.0 hypothetical protein (NCBI) compare
b0912 ihfB -0.4 -0.9 integration host factor subunit beta (NCBI) compare
b2569 lepA -0.4 -1.7 GTP-binding protein LepA (NCBI) compare
b1819 manZ -0.4 -2.2 mannose-specific enzyme IID component of PTS (NCBI) compare
b2111 yehD -0.4 -1.6 predicted fimbrial-like adhesin protein (NCBI) compare
b3728 pstS -0.4 -1.9 phosphate transporter subunit (NCBI) compare
b1973 yodA -0.4 -1.8 conserved metal-binding protein (NCBI) compare
b2741 rpoS -0.4 -2.5 RNA polymerase sigma factor (NCBI) compare
b2207 napD -0.4 -2.1 assembly protein for periplasmic nitrate reductase (NCBI) compare
b1343 dbpA -0.4 -1.6 ATP-dependent RNA helicase, specific for 23S rRNA (NCBI) compare
b1412 azoR -0.4 -1.1 acyl carrier protein phosphodiesterase (NCBI) compare
b1861 ruvA -0.4 -0.4 Holliday junction DNA helicase motor protein (NCBI) compare
b1424 mdoD -0.4 -2.1 glucan biosynthesis protein, periplasmic (RefSeq) compare
b3836 b3836 -0.4 -1.8 orf, hypothetical protein (VIMSS) compare
b4589 ylcI -0.4 -1.3 hypothetical protein (RefSeq) compare
b4407 thiS -0.4 -0.9 sulfur carrier protein ThiS (NCBI) compare
b3119 tdcR -0.4 -1.3 threonine dehydratase operon activator protein (VIMSS) compare
b3627 rfaI -0.4 -2.9 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b1171 b1171 -0.4 -1.2 orf, hypothetical protein (VIMSS) compare
b1842 holE -0.3 -0.9 DNA polymerase III, theta subunit (NCBI) compare
b1818 manY -0.3 -1.3 mannose-specific enzyme IIC component of PTS (NCBI) compare
b4194 ulaB -0.3 -1.6 L-ascorbate-specific enzyme IIB component of PTS (NCBI) compare
b1235 rssB -0.3 -2.1 response regulator of RpoS (NCBI) compare
b0610 rnk -0.3 -1.8 nucleoside diphosphate kinase regulator (NCBI) compare
b1176 minC -0.3 -0.8 septum formation inhibitor (NCBI) compare
b2093 gatB -0.3 -2.1 galactitol-specific enzyme IIB component of PTS (NCBI) compare
b2706 gutM -0.3 -2.2 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b1970 yedX -0.3 -1.5 hypothetical protein (NCBI) compare
b3787 rffD -0.3 -2.8 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b1667 ydhR -0.3 -1.4 hypothetical protein (NCBI) compare
b3977 tyrU -0.3 -0.5 tRNA-Tyr (NCBI) compare
b2299 yfcD -0.3 -1.9 predicted NUDIX hydrolase (NCBI) compare
b0234 yafP -0.3 -0.9 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b4481 rffT -0.3 -2.4 4-alpha-L-fucosyltransferase (NCBI) compare
b2156 lysP -0.3 -2.7 lysine transporter (NCBI) compare
b0503 ybbB -0.3 -1.9 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b3082 ygjM -0.3 -0.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b1594 dgsA -0.3 -1.2 DNA-binding transcriptional repressor (NCBI) compare
b3626 rfaJ -0.3 -2.0 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b1177 ycgJ -0.3 -2.1 hypothetical protein (NCBI) compare
b2285 nuoE -0.3 -1.2 NADH dehydrogenase subunit E (NCBI) compare
b1777 b1777 -0.3 -1.0 orf, hypothetical protein (VIMSS) compare
b0931 pncB -0.3 -1.7 nicotinate phosphoribosyltransferase (NCBI) compare
b1012 b1012 -0.3 -2.1 orf, hypothetical protein (VIMSS) compare
b1628 rsxB -0.3 -1.1 electron transport complex protein RnfB (NCBI) compare
b1865 nudB -0.3 -0.4 dATP pyrophosphohydrolase (NCBI) compare
b1270 btuR -0.3 -1.7 cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) compare
b1196 ycgY -0.3 -1.3 hypothetical protein (NCBI) compare
b3838 tatB -0.3 -2.0 sec-independent translocase (NCBI) compare
b0226 dinJ -0.3 -1.4 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b2288 nuoA -0.3 -1.2 NADH dehydrogenase I chain A (VIMSS) compare
b1148 ymfM -0.3 -1.3 e14 prophage; predicted protein (NCBI) compare
b0767 ybhE -0.3 -1.7 6-phosphogluconolactonase (NCBI) compare
b4651 yibW -0.3 -0.2 no description compare
b1441 ydcT -0.3 -1.3 predicted spermidine/putrescine transporter subunit (NCBI) compare
b3784 rfe -0.3 -2.6 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3163 nlpI -0.3 -1.3 hypothetical protein (NCBI) compare
b3630 rfaP -0.3 -2.5 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b0655 gltI -0.3 -2.0 glutamate and aspartate transporter subunit (NCBI) compare
b0881 clpS -0.3 -0.9 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b0782 moaB -0.3 -1.2 molybdopterin biosynthesis protein B (NCBI) compare
b1464 yddE -0.3 -1.5 hypothetical protein (NCBI) compare
b2123 yehR -0.3 -1.3 orf, hypothetical protein (VIMSS) compare
b2175 spr -0.3 -1.4 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b0908 aroA -0.3 -2.1 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b2007 yeeX -0.3 -1.0 conserved protein (RefSeq) compare
b4012 yjaB -0.3 -0.9 predicted acetyltransferase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments