Experiment set41IT062 for Escherichia coli BW25113

Compare to:

LB Time1hr

200 most detrimental genes:

  gene name fitness t score description  
b3979 thrT +1.8 0.7 tRNA-Thr (NCBI) compare
b2934 cmtB +1.5 1.3 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b4676 yoaK +1.1 1.2 expressed protein (RefSeq) compare
b1161 ycgX +1.1 2.2 hypothetical protein (NCBI) compare
b1361 ydaW +1.1 0.9 orf, hypothetical protein (VIMSS) compare
b1936 intG +1.1 1.9 predicted defective phage integrase (pseudogene) (RefSeq) compare
b0730 mngR +1.1 2.3 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1332 ynaJ +1.0 0.6 predicted inner membrane protein (NCBI) compare
b4538 yoeF +1.0 2.8 hypothetical protein (RefSeq) compare
b0630 lipB +0.9 1.6 protein of lipoate biosynthesis (VIMSS) compare
b1351 racC +0.7 0.6 Rac prophage; predicted protein (NCBI) compare
b4640 yoeG +0.7 2.4 no description compare
b1363 trkG +0.7 0.5 Rac prophage; potassium transporter subunit (NCBI) compare
b1348 lar +0.7 1.7 Rac prophage; restriction alleviation protein (NCBI) compare
b4505 insX +0.7 1.9 predicted IS protein (RefSeq) compare
b2071 yegJ +0.6 2.3 hypothetical protein (NCBI) compare
b2209 eco +0.6 1.4 ecotin precursor (NCBI) compare
b0310 ykgH +0.6 1.3 predicted inner membrane protein (NCBI) compare
b1409 ynbB +0.6 0.6 predicted CDP-diglyceride synthase (NCBI) compare
b1545 pinQ +0.6 0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1499 ydeO +0.6 0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1576 ydfD +0.6 0.3 Qin prophage; predicted protein (NCBI) compare
b4653 yicT +0.6 1.8 no description compare
b2165 yeiN +0.5 2.9 hypothetical protein (NCBI) compare
b1497 b1497 +0.5 0.3 putative enzyme (VIMSS) compare
b0388 aroL +0.5 2.8 shikimate kinase II (NCBI) compare
b1258 yciF +0.5 0.7 hypothetical protein (NCBI) compare
b1919 yedO +0.5 1.3 putative 1-aminocyclopropane-1-carboxylate deaminase (VIMSS) compare
b4239 treC +0.4 0.8 trehalose-6-P hydrolase (NCBI) compare
b1195 ymgE +0.4 2.3 predicted inner membrane protein (NCBI) compare
b2051 wcaH +0.4 1.3 GDP-mannose mannosyl hydrolase (VIMSS) compare
b1848 yebG +0.4 1.2 conserved protein regulated by LexA (NCBI) compare
b4551 yheV +0.4 2.2 hypothetical protein (NCBI) compare
b2809 b2809 +0.4 2.5 orf, hypothetical protein (VIMSS) compare
b1462 b1462 +0.4 1.2 orf, hypothetical protein (VIMSS) compare
b1558 cspF +0.4 1.6 Qin prophage; cold shock protein (NCBI) compare
b0535 fimZ +0.4 1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b4181 yjfI +0.4 2.5 hypothetical protein (NCBI) compare
b2859 ygeO +0.4 1.4 hypothetical protein (RefSeq) compare
b1523 yneG +0.4 1.3 hypothetical protein (NCBI) compare
b2352 yfdI +0.4 0.7 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b4152 frdC +0.4 2.7 fumarate reductase subunit C (NCBI) compare
b0542 renD +0.4 1.2 orf, hypothetical protein (VIMSS) compare
b0641 rlpB +0.4 2.0 minor lipoprotein (NCBI) compare
b3100 yqjK +0.4 2.4 hypothetical protein (NCBI) compare
b1257 yciE +0.4 0.2 hypothetical protein (NCBI) compare
b4596 yciZ +0.4 1.0 hypothetical protein (RefSeq) compare
b0802 ybiJ +0.4 1.9 hypothetical protein (NCBI) compare
b2699 recA +0.4 0.6 recombinase A (NCBI) compare
b1408 b1408 +0.4 2.1 probable enzyme (VIMSS) compare
b2017 yefM +0.4 0.3 orf, hypothetical protein (VIMSS) compare
b1954 dsrA +0.4 1.5 regulatory antisense RNA (NCBI) compare
b2141 yohJ +0.4 2.2 hypothetical protein (NCBI) compare
b1753 ynjA +0.4 1.5 hypothetical protein (NCBI) compare
b2445 yffN +0.4 1.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b1427 rimL +0.4 1.6 ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) compare
b1330 ynaI +0.4 2.0 conserved inner membrane protein (NCBI) compare
b4494 arpB +0.4 0.9 no description compare
b3512 GadE +0.3 2.2 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b4573 insZ +0.3 1.9 no description compare
b1742 b1742 +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b4445 omrB +0.3 2.1 sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq (RefSeq) compare
b3238 yhcN +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b0218 yafU +0.3 1.5 predicted inner membrane protein (RefSeq) compare
b1768 ydjB +0.3 2.0 orf, hypothetical protein (VIMSS) compare
b0803 ybiI +0.3 1.4 hypothetical protein (NCBI) compare
b0407 yajC +0.3 1.0 preprotein translocase subunit YajC (NCBI) compare
b4546 ypeB +0.3 0.7 hypothetical protein (NCBI) compare
b0933 ssuB +0.3 1.7 alkanesulfonate transporter subunit (NCBI) compare
b0696 kdpC +0.3 1.1 potassium-transporting ATPase subunit C (NCBI) compare
b2853 ygeI +0.3 0.2 hypothetical protein (NCBI) compare
b0440 hupB +0.3 2.3 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b1763 topB +0.3 2.2 DNA topoisomerase III (NCBI) compare
b1167 ymgC +0.3 0.2 hypothetical protein (NCBI) compare
b1165 ymgA +0.3 0.2 hypothetical protein (NCBI) compare
b2510 b2510 +0.3 1.5 orf, hypothetical protein (VIMSS) compare
b1344 ydaO +0.3 1.2 predicted C32 tRNA thiolase (NCBI) compare
b0456 ybaA +0.3 1.2 hypothetical protein (NCBI) compare
b3443 yrhA +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b0846 ybjK +0.3 1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b4497 yeeL +0.3 0.5 no description compare
b1566 flxA +0.3 1.4 Qin prophage; predicted protein (NCBI) compare
b4646 yrdE +0.3 1.5 no description compare
b1506 yneL +0.3 0.6 predicted transcriptional regulator (NCBI) compare
b0798 ybiA +0.3 0.6 hypothetical protein (NCBI) compare
b1038 csgF +0.3 1.3 predicted transport protein (NCBI) compare
b1969 yedW +0.3 1.7 putative 2-component transcriptional regulator (VIMSS) compare
b0645 ybeR +0.3 2.2 hypothetical protein (NCBI) compare
b1407 ydbD +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b3361 fic +0.3 1.4 stationary-phase protein, cell division (NCBI) compare
b4509 ylcG +0.3 1.2 DLP12 prophage; predicted protein (NCBI) compare
b2212 alkB +0.3 1.4 oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions (NCBI) compare
b2444 yffM +0.3 0.9 CPZ-55 prophage; predicted protein (NCBI) compare
b4157 yjeN +0.3 1.4 hypothetical protein (NCBI) compare
b4441 glmY +0.3 0.9 sRNA activator of glmS mRNA (RefSeq) compare
b3120 yhaB +0.3 0.8 orf, hypothetical protein (VIMSS) compare
b2577 yfiE +0.3 1.9 putative transcriptional regulator LYSR-type (VIMSS) compare
b0738 tolR +0.3 0.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1698 ydiR +0.3 1.5 predicted electron transfer flavoprotein, FAD-binding (NCBI) compare
b3037 ygiB +0.3 1.6 conserved outer membrane protein (RefSeq) compare
b1536 ydeI +0.3 0.4 hypothetical protein (NCBI) compare
b1557 cspB +0.3 0.7 Qin prophage; cold shock protein (NCBI) compare
b1130 phoP +0.3 0.5 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b1205 ychH +0.3 0.6 predicted inner membrane protein (NCBI) compare
b1519 tam +0.3 1.3 trans-aconitate 2-methyltransferase (NCBI) compare
b0228 yafM +0.3 1.6 hypothetical protein (NCBI) compare
b1858 znuC +0.3 1.9 high-affinity zinc transporter ATPase (NCBI) compare
b1696 ydiP +0.3 1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1143 ymfI +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b1259 yciG +0.3 0.6 orf, hypothetical protein (VIMSS) compare
b2456 cchB +0.3 1.5 predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) compare
b4579 yaiX +0.3 1.8 no description compare
b4656 yjhY +0.3 2.0 no description compare
b2202 napC +0.3 1.8 nitrate reductase, cytochrome c-type, periplasmic (NCBI) compare
b1217 chaB +0.3 0.6 cation transport regulator (NCBI) compare
b1883 cheB +0.3 1.4 chemotaxis-specific methylesterase (NCBI) compare
b1044 ymdA +0.3 1.7 hypothetical protein (NCBI) compare
b1138 ymfE +0.3 0.7 e14 prophage; predicted inner membrane protein (NCBI) compare
b4631 ykgQ +0.3 1.0 no description compare
b2587 kgtP +0.3 1.7 alpha-ketoglutarate transporter (NCBI) compare
b0864 artP +0.3 1.4 arginine transporter subunit (NCBI) compare
b1362 rzpR +0.3 1.0 putative Rac prophage endopeptidase (VIMSS) compare
b0623 cspE +0.3 0.7 cold shock protein E (NCBI) compare
b3775 ppiC +0.3 1.1 peptidyl-prolyl cis-trans isomerase C (rotamase C) (NCBI) compare
b1847 yebF +0.3 0.5 predicted protein (RefSeq) compare
b3125 garR +0.3 1.8 tartronate semialdehyde reductase (RefSeq) compare
b1025 ycdT +0.3 0.6 predicted diguanylate cyclase (NCBI) compare
b4277 yjgZ +0.3 1.6 KpLE2 phage-like element; predicted protein (NCBI) compare
b1113 ycfS +0.3 1.6 hypothetical protein (NCBI) compare
b1013 ycdC +0.3 0.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b0946 ycbW +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b1831 proQ +0.3 1.1 putative solute/DNA competence effector (NCBI) compare
b2134 pbpG +0.3 1.7 penicillin-binding protein 7 (VIMSS) compare
b1309 ycjM +0.3 1.4 putative polysaccharide hydrolase (VIMSS) compare
b0998 torD +0.3 0.5 chaperone protein TorD (NCBI) compare
b0606 ahpF +0.2 1.8 alkyl hydroperoxide reductase, F52a subunit; detoxification of hydroperoxides (VIMSS) compare
b1581 rspA +0.2 1.1 predicted dehydratase (NCBI) compare
b1337 abgB +0.2 1.3 predicted peptidase, aminobenzoyl-glutamate utilization protein (NCBI) compare
b2287 nuoB +0.2 1.3 NADH dehydrogenase subunit B (NCBI) compare
b0726 sucA +0.2 1.3 alpha-ketoglutarate decarboxylase (NCBI) compare
b2208 napF +0.2 1.2 ferredoxin-type protein, predicted role in electron transfer to periplasmic nitrate reductase (NapA) (NCBI) compare
b1308 pspE +0.2 1.2 thiosulfate:cyanide sulfurtransferase (rhodanese) (NCBI) compare
b4394 yjjX +0.2 1.3 orf, hypothetical protein (VIMSS) compare
b0547 ybcN +0.2 1.5 DLP12 prophage; predicted protein (NCBI) compare
b0714 nei +0.2 1.1 endonuclease VIII/ 5-formyluracil/5-hydroxymethyluracil DNA glycosylase (NCBI) compare
b1162 ycgE +0.2 1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3962 udhA +0.2 1.9 putative oxidoreductase (VIMSS) compare
b2561 yfhH +0.2 1.8 orf, hypothetical protein (VIMSS) compare
b1672 ydhW +0.2 1.0 hypothetical protein (NCBI) compare
b1276 acnA +0.2 1.7 aconitate hydratase (NCBI) compare
b1520 b1520 +0.2 1.3 orf, hypothetical protein (VIMSS) compare
b1139 lit +0.2 1.4 e14 prophage; cell death peptidase, inhibitor of T4 late gene expression (NCBI) compare
b3555 yiaG +0.2 1.4 predicted transcriptional regulator (NCBI) compare
b2355 yfdL +0.2 2.1 CPS-53 (KpLE1) prophage; conserved protein (RefSeq) compare
b4363 yjjB +0.2 1.2 conserved inner membrane protein (RefSeq) compare
b1693 aroD +0.2 1.1 3-dehydroquinate dehydratase (NCBI) compare
b1450 b1450 +0.2 1.5 orf, hypothetical protein (VIMSS) compare
b1434 ydcN +0.2 0.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b1134 ymfB +0.2 0.7 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase (NCBI) compare
b1251 yciI +0.2 1.2 orf, hypothetical protein (VIMSS) compare
b0411 tsx +0.2 1.8 nucleoside channel, receptor of phage T6 and colicin K (NCBI) compare
b0611 rna +0.2 1.6 ribonuclease I (NCBI) compare
b0102 yacF +0.2 1.1 hypothetical protein (NCBI) compare
b0192 nlpE +0.2 1.7 lipoprotein involved with copper homeostasis and adhesion (NCBI) compare
b0225 yafQ +0.2 1.0 predicted toxin of the YafQ-DinJ toxin-antitoxin system (NCBI) compare
b0942 ycbU +0.2 1.3 predicted fimbrial-like adhesin protein (NCBI) compare
b1884 cheR +0.2 1.3 chemotaxis regulator, protein-glutamate methyltransferase (NCBI) compare
b1058 yceO +0.2 0.1 hypothetical protein (NCBI) compare
b3973 birA +0.2 1.1 biotin--protein ligase (NCBI) compare
b0439 lon +0.2 1.0 DNA-binding ATP-dependent protease La (NCBI) compare
b1357 ydaS +0.2 0.8 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b1707 ydiV +0.2 1.1 hypothetical protein (NCBI) compare
b0443 ybaW +0.2 1.4 hypothetical protein (NCBI) compare
b1168 b1168 +0.2 1.1 putative proteases (VIMSS) compare
b4634 ylcF +0.2 1.7 no description compare
b2486 hyfF +0.2 1.4 NADH dehydrogenase subunit N (NCBI) compare
b2804 fucU +0.2 1.1 L-fucose mutarotase (NCBI) compare
b2843 kduI +0.2 1.6 5-keto-4-deoxyuronate isomerase (NCBI) compare
b1734 chbF +0.2 1.5 cryptic phospho-beta-glucosidase, NAD(P)-binding (NCBI) compare
b3270 yhdY +0.2 1.8 putative transport system permease protein (VIMSS) compare
b1948 fliP +0.2 1.2 flagellar biosynthesis protein P (NCBI) compare
b2481 hyfA +0.2 1.4 hydrogenase 4 Fe-S subunit (VIMSS) compare
b4513 kdpF +0.2 0.9 potassium ion accessory transporter subunit (NCBI) compare
b1691 ydiN +0.2 1.0 predicted transporter (RefSeq) compare
b2622 intA +0.2 1.5 CP4-57 prophage; integrase (NCBI) compare
b1156 tfaE +0.2 1.3 e14 prophage; predicted tail fiber assembly protein (NCBI) compare
b4595 yciY +0.2 0.8 hypothetical protein (RefSeq) compare
b4464 ygfQ +0.2 1.6 predicted transporter (NCBI) compare
b1299 puuR +0.2 1.4 DNA-binding transcriptional repressor (NCBI) compare
b0442 ybaV +0.2 1.6 hypothetical protein (NCBI) compare
b2058 wcaB +0.2 0.5 predicted acyl transferase (NCBI) compare
b1590 ynfH +0.2 1.1 oxidoreductase, membrane subunit (NCBI) compare
b1063 yceB +0.2 1.0 predicted lipoprotein (NCBI) compare
b1387 maoC +0.2 1.4 fused aldehyde dehydrogenase/enoyl-CoA hydratase (NCBI) compare
b1683 ynhE +0.2 1.4 orf, hypothetical protein (VIMSS) compare
b2362 yfdS +0.2 0.8 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2635 ypjK +0.2 1.3 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b0754 aroG +0.2 1.5 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible (NCBI) compare
b4480 hdfR +0.2 1.3 transcriptional regulator HdfR (NCBI) compare
b1709 btuD +0.2 0.2 vitamin B12-transporter ATPase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in lb experiments