| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -10.5 | -4.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b1260 | trpA | -10.0 | -2.9 | tryptophan synthase subunit alpha (NCBI) | compare |
| b4245 | pyrB | -8.6 | -6.0 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b2026 | hisI | -8.6 | -4.0 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b2818 | argA | -8.5 | -5.4 | N-acetylglutamate synthase (NCBI) | compare |
| b0238 | gpt | -8.5 | -3.0 | xanthine phosphoribosyltransferase (NCBI) | compare |
| b0242 | proB | -8.5 | -4.3 | gamma-glutamyl kinase (NCBI) | compare |
| b0907 | serC | -8.4 | -4.3 | phosphoserine aminotransferase (NCBI) | compare |
| b0072 | leuC | -8.4 | -5.8 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b1261 | trpB | -8.4 | -2.1 | tryptophan synthase subunit beta (NCBI) | compare |
| b2020 | hisD | -8.3 | -4.7 | histidinol dehydrogenase (NCBI) | compare |
| b0073 | leuB | -8.3 | -5.7 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2476 | purC | -8.2 | -2.0 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3172 | argG | -8.0 | -5.5 | argininosuccinate synthase (NCBI) | compare |
| b4630 | ykgP | -8.0 | -2.0 | no description | compare |
| b0071 | leuD | -7.9 | -4.6 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b3008 | metC | -7.7 | -12.9 | cystathionine beta-lyase (NCBI) | compare |
| b3774 | ilvC | -7.5 | -18.2 | ketol-acid reductoisomerase (NCBI) | compare |
| b3198 | kdsC | -7.5 | -2.4 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) | compare |
| b4006 | purH | -7.4 | -5.1 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2312 | purF | -7.4 | -4.1 | amidophosphoribosyltransferase (NCBI) | compare |
| b0782 | moaB | -7.3 | -1.8 | molybdopterin biosynthesis protein B (NCBI) | compare |
| b1281 | pyrF | -7.2 | -2.5 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b3029 | ygiN | -7.2 | -2.1 | quinol monooxygenase (NCBI) | compare |
| b3770 | ilvE | -7.2 | -17.4 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b4388 | serB | -7.2 | -4.3 | 3-phosphoserine phosphatase (NCBI) | compare |
| b0720 | gltA | -7.0 | -4.3 | citrate synthase (NCBI) | compare |
| b3941 | metF | -6.9 | -8.6 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b4695 | ykgT | -6.9 | -1.7 | no description | compare |
| b4041 | plsB | -6.9 | -1.0 | glycerol-3-phosphate acyltransferase (VIMSS) | compare |
| b3957 | argE | -6.8 | -13.1 | acetylornithine deacetylase (NCBI) | compare |
| b3389 | aroB | -6.7 | -14.1 | 3-dehydroquinate synthase (NCBI) | compare |
| b2025 | hisF | -6.7 | -2.7 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b0113 | pdhR | -6.6 | -3.4 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b0003 | thrB | -6.6 | -9.7 | homoserine kinase (NCBI) | compare |
| b2814 | metZ | -6.6 | -0.9 | tRNA-Met (NCBI) | compare |
| b2750 | cysC | -6.6 | -6.7 | adenylylsulfate kinase (NCBI) | compare |
| b0386 | proC | -6.6 | -4.2 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b1263 | trpD | -6.5 | -2.1 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b4570 | lomR | -6.5 | -1.6 | no description | compare |
| b2329 | aroC | -6.4 | -3.8 | chorismate synthase (NCBI) | compare |
| b0739 | tolA | -6.3 | -4.0 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b1248 | b1248 | -6.2 | -1.3 | orf, hypothetical protein (VIMSS) | compare |
| b3642 | pyrE | -6.1 | -3.1 | orotate phosphoribosyltransferase (NCBI) | compare |
| b1147 | ymfL | -6.1 | -2.1 | e14 prophage; predicted DNA-binding transcriptional regulator (RefSeq) | compare |
| b0033 | carB | -6.1 | -12.8 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b1850 | eda | -6.0 | -1.7 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b3281 | aroE | -6.0 | -16.6 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0243 | proA | -5.9 | -10.7 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0018 | mokC | -5.8 | -0.8 | regulatory protein for HokC, overlaps CDS of hokC (NCBI) | compare |
| b2479 | gcvR | -5.8 | -3.7 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2501 | ppk | -5.8 | -13.3 | polyphosphate kinase (NCBI) | compare |
| b0074 | leuA | -5.8 | -9.1 | 2-isopropylmalate synthase (NCBI) | compare |
| b1984 | asnW | -5.7 | -0.8 | tRNA-Asn (NCBI) | compare |
| b1865 | nudB | -5.7 | -1.4 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1217 | chaB | -5.7 | -1.4 | cation transport regulator (NCBI) | compare |
| b2024 | hisA | -5.7 | -1.1 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3771 | ilvD | -5.6 | -11.8 | dihydroxy-acid dehydratase (NCBI) | compare |
| b0623 | cspE | -5.6 | -1.1 | cold shock protein E (NCBI) | compare |
| b2285 | nuoE | -5.5 | -1.7 | NADH dehydrogenase subunit E (NCBI) | compare |
| b4529 | ydbJ | -5.5 | -0.8 | hypothetical protein (NCBI) | compare |
| b2762 | cysH | -5.4 | -8.5 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0002 | thrA | -5.4 | -11.0 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b2838 | lysA | -5.4 | -8.8 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b4546 | ypeB | -5.3 | -0.8 | hypothetical protein (NCBI) | compare |
| b4613 | dinQ | -5.3 | -1.1 | Damage inducible, function unknown (RefSeq) | compare |
| b1465 | narV | -5.3 | -1.0 | nitrate reductase 2 (NRZ), gamma subunit (NCBI) | compare |
| b4005 | purD | -5.2 | -8.6 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b2017 | yefM | -5.2 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b2764 | cysJ | -5.2 | -9.9 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b1231 | tyrT | -5.1 | -0.7 | tRNA-Tyr (NCBI) | compare |
| b4013 | metA | -5.1 | -4.2 | homoserine O-succinyltransferase (NCBI) | compare |
| b3939 | metB | -5.1 | -8.7 | cystathionine gamma-synthase (NCBI) | compare |
| b4214 | cysQ | -5.1 | -10.1 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b1205 | ychH | -5.1 | -1.0 | predicted inner membrane protein (NCBI) | compare |
| b1062 | pyrC | -5.1 | -7.5 | dihydroorotase (NCBI) | compare |
| b1429 | tehA | -5.1 | -1.2 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b2318 | truA | -5.0 | -2.4 | tRNA pseudouridine synthase A (NCBI) | compare |
| b3484 | yhhI | -5.0 | -2.0 | predicted transposase (NCBI) | compare |
| b3772 | ilvA | -5.0 | -10.1 | threonine dehydratase (NCBI) | compare |
| b2913 | serA | -5.0 | -8.9 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b0145 | dksA | -5.0 | -2.3 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b2414 | cysK | -5.0 | -6.3 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b2911 | ssrS | -5.0 | -1.0 | 6S regulatory RNA (NCBI) | compare |
| b2022 | hisB | -4.9 | -6.5 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b1183 | umuD | -4.9 | -1.0 | DNA polymerase V, subunit D (NCBI) | compare |
| b2279 | nuoK | -4.9 | -1.4 | NADH dehydrogenase subunit K (NCBI) | compare |
| b3868 | glnG | -4.8 | -6.1 | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | compare |
| b4699 | fnrS | -4.8 | -0.7 | FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) | compare |
| b1942 | fliJ | -4.8 | -1.0 | flagellar biosynthesis chaperone (NCBI) | compare |
| b2557 | purL | -4.8 | -9.9 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0014 | dnaK | -4.7 | -1.5 | molecular chaperone DnaK (NCBI) | compare |
| b0004 | thrC | -4.7 | -5.8 | threonine synthase (NCBI) | compare |
| b2488 | hyfH | -4.7 | -2.4 | hydrogenase 4, Fe-S subunit (NCBI) | compare |
| b1550 | b1550 | -4.6 | -0.9 | orf, hypothetical protein (VIMSS) | compare |
| b3958 | argC | -4.6 | -7.7 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b0908 | aroA | -4.6 | -8.1 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3956 | ppc | -4.6 | -11.9 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2763 | cysI | -4.5 | -7.1 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b0522 | purK | -4.5 | -7.8 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b4655 | ythA | -4.5 | -1.1 | expressed protein (RefSeq) | compare |
| b3613 | yibP | -4.5 | -8.4 | putative membrane protein (VIMSS) | compare |
| b1493 | gadB | -4.5 | -0.6 | glutamate decarboxylase B, PLP-dependent (NCBI) | compare |
| b4603 | rseX | -4.5 | -0.6 | sRNA regulating ompA and ompC translation, with Hfq (RefSeq) | compare |
| b3959 | argB | -4.4 | -6.9 | acetylglutamate kinase (RefSeq) | compare |
| b2839 | lysR | -4.4 | -3.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2023 | hisH | -4.4 | -3.9 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b3960 | argH | -4.4 | -7.7 | argininosuccinate lyase (NCBI) | compare |
| b1358 | ydaT | -4.3 | -0.9 | Rac prophage; predicted protein (NCBI) | compare |
| b1361 | ydaW | -4.3 | -0.6 | orf, hypothetical protein (VIMSS) | compare |
| b0439 | lon | -4.2 | -7.8 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0683 | fur | -4.2 | -1.0 | ferric uptake regulator (NCBI) | compare |
| b2363 | yfdT | -4.2 | -1.8 | CPS-53 (KpLE1) prophage; predicted protein (NCBI) | compare |
| b3368 | cysG | -4.1 | -10.2 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b1693 | aroD | -4.1 | -3.9 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b3183 | obgE | -4.1 | -1.2 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b1861 | ruvA | -4.1 | -1.3 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0740 | tolB | -4.0 | -6.0 | translocation protein TolB precursor (NCBI) | compare |
| b2498 | upp | -4.0 | -2.0 | uracil phosphoribosyltransferase (VIMSS) | compare |
| b2021 | hisC | -4.0 | -4.2 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b1291 | sapD | -3.9 | -1.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2600 | tyrA | -3.9 | -4.0 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b0912 | ihfB | -3.9 | -2.5 | integration host factor subunit beta (NCBI) | compare |
| b2019 | hisG | -3.8 | -3.1 | ATP phosphoribosyltransferase (NCBI) | compare |
| b0032 | carA | -3.8 | -4.1 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b0738 | tolR | -3.8 | -4.6 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0990 | cspG | -3.7 | -0.9 | DNA-binding transcriptional regulator (NCBI) | compare |
| b1921 | fliZ | -3.7 | -3.0 | orf, hypothetical protein (VIMSS) | compare |
| b2168 | fruK | -3.7 | -0.9 | 1-phosphofructokinase (NCBI) | compare |
| b2642 | yfjW | -3.7 | -0.9 | CP4-57 prophage; predicted inner membrane protein (NCBI) | compare |
| b1863 | ruvC | -3.7 | -1.6 | Holliday junction resolvase (NCBI) | compare |
| b1262 | trpC | -3.6 | -4.4 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b0737 | tolQ | -3.6 | -2.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3773 | ilvY | -3.5 | -5.6 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3781 | trxA | -3.5 | -2.9 | thioredoxin 1 (VIMSS) | compare |
| b2313 | cvpA | -3.5 | -2.1 | membrane protein required for colicin V production (NCBI) | compare |
| b1264 | trpE | -3.5 | -3.7 | anthranilate synthase component I (NCBI) | compare |
| b2499 | purM | -3.5 | -3.1 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b1882 | cheY | -3.5 | -0.5 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b1252 | tonB | -3.4 | -2.9 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b3026 | qseC | -3.4 | -2.3 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b1259 | yciG | -3.3 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b2284 | nuoF | -3.3 | -4.7 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b4535 | yniD | -3.2 | -1.0 | predicted protein (RefSeq) | compare |
| b4042 | dgkA | -3.2 | -1.6 | diacylglycerol kinase (NCBI) | compare |
| b0232 | yafN | -3.2 | -0.6 | predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) | compare |
| b1290 | sapF | -3.2 | -1.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0142 | folK | -3.1 | -0.4 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b1038 | csgF | -3.1 | -2.1 | predicted transport protein (NCBI) | compare |
| b4676 | yoaK | -3.1 | -0.6 | expressed protein (RefSeq) | compare |
| b3082 | ygjM | -3.1 | -1.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3791 | rffA | -3.0 | -5.6 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b0945 | pyrD | -3.0 | -6.7 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0784 | moaD | -3.0 | -2.1 | molybdopterin synthase, small subunit (NCBI) | compare |
| b0200 | gmhB | -3.0 | -1.2 | hypothetical protein (NCBI) | compare |
| b4520 | ymgF | -3.0 | -1.0 | hypothetical protein (NCBI) | compare |
| b0957 | ompA | -2.9 | -2.6 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b0437 | clpP | -2.9 | -4.0 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b0817 | mntR | -2.9 | -1.8 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b0741 | pal | -2.9 | -3.6 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0125 | hpt | -2.9 | -3.3 | hypoxanthine phosphoribosyltransferase (VIMSS) | compare |
| b2895 | fldB | -2.9 | -2.1 | flavodoxin 2 (NCBI) | compare |
| b0585 | fes | -2.9 | -4.2 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b2599 | pheA | -2.8 | -4.0 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b3621 | rfaC | -2.8 | -6.2 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b1506 | yneL | -2.8 | -1.0 | predicted transcriptional regulator (NCBI) | compare |
| b0707 | ybgA | -2.8 | -3.1 | hypothetical protein (NCBI) | compare |
| b4481 | rffT | -2.8 | -4.8 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3035 | tolC | -2.8 | -4.9 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b3792 | wzxE | -2.8 | -6.3 | O-antigen translocase (NCBI) | compare |
| b4402 | yjjY | -2.8 | -0.5 | hypothetical protein (NCBI) | compare |
| b1677 | lpp | -2.8 | -1.5 | murein lipoprotein (NCBI) | compare |
| b2504 | yfgG | -2.7 | -1.2 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b1712 | ihfA | -2.7 | -0.9 | integration host factor subunit alpha (NCBI) | compare |
| b4435 | isrC | -2.7 | -1.0 | unknown RNA (NCBI) | compare |
| b0141 | yadN | -2.7 | -8.1 | predicted fimbrial-like adhesin protein (NCBI) | compare |
| b3205 | yhbJ | -2.7 | -3.0 | hypothetical protein (NCBI) | compare |
| b1185 | dsbB | -2.6 | -1.8 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b1306 | pspC | -2.6 | -1.9 | DNA-binding transcriptional activator (NCBI) | compare |
| b0890 | ftsK | -2.6 | -8.7 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b3261 | fis | -2.6 | -3.0 | DNA-binding protein Fis (NCBI) | compare |
| b4426 | isrA | -2.6 | -1.6 | unknown RNA (NCBI) | compare |
| b3790 | rffC | -2.5 | -3.3 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b3916 | pfkA | -2.5 | -1.7 | 6-phosphofructokinase (NCBI) | compare |
| b3052 | rfaE | -2.5 | -4.5 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2071 | yegJ | -2.5 | -0.7 | hypothetical protein (NCBI) | compare |
| b3728 | pstS | -2.5 | -1.7 | phosphate transporter subunit (NCBI) | compare |
| b0564 | appY | -2.5 | -0.5 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3839 | tatC | -2.5 | -5.1 | TatABCE protein translocation system subunit (NCBI) | compare |
| b2959 | yggL | -2.5 | -1.5 | orf, hypothetical protein (VIMSS) | compare |
| b0456 | ybaA | -2.5 | -2.2 | hypothetical protein (NCBI) | compare |
| b2252 | ais | -2.4 | -6.8 | hypothetical protein (NCBI) | compare |
| b1427 | rimL | -2.4 | -1.3 | ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) | compare |
| b4701 | sokX | -2.4 | -0.5 | sok-related sRNA, function unknown (RefSeq) | compare |
| b2699 | recA | -2.4 | -1.1 | recombinase A (NCBI) | compare |
| b1600 | mdtJ | -2.4 | -2.5 | multidrug efflux system transporter (NCBI) | compare |
| b1013 | ycdC | -2.4 | -1.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3414 | gntY | -2.4 | -3.7 | predicted gluconate transport associated protein (NCBI) | compare |
| b0589 | fepG | -2.4 | -3.4 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0812 | dps | -2.4 | -3.3 | DNA protection during starvation conditions (NCBI) | compare |