| | gene | name | fitness | t score | description | |
|---|
| b4460 | araH | -8.2 | -2.3 | fused L-arabinose transporter subunits of ABC superfamily: membrane components (RefSeq) | compare |
| b1261 | trpB | -8.0 | -2.3 | tryptophan synthase subunit beta (NCBI) | compare |
| b0073 | leuB | -7.9 | -5.5 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2476 | purC | -7.9 | -2.2 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0243 | proA | -7.7 | -5.4 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0242 | proB | -7.5 | -5.9 | gamma-glutamyl kinase (NCBI) | compare |
| b2023 | hisH | -7.2 | -3.9 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b4005 | purD | -7.0 | -4.8 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b1281 | pyrF | -6.9 | -2.7 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b4388 | serB | -6.8 | -4.6 | 3-phosphoserine phosphatase (NCBI) | compare |
| b4045 | yjbJ | -6.8 | -1.9 | predicted stress response protein (NCBI) | compare |
| b3772 | ilvA | -6.7 | -15.6 | threonine dehydratase (NCBI) | compare |
| b2022 | hisB | -6.7 | -4.6 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2450 | yffS | -6.6 | -1.9 | CPZ-55 prophage; predicted protein (RefSeq) | compare |
| b3774 | ilvC | -6.6 | -16.3 | ketol-acid reductoisomerase (NCBI) | compare |
| b3956 | ppc | -6.5 | -21.3 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b4533 | ynfO | -6.4 | -2.1 | Qin prophage; predicted protein (NCBI) | compare |
| b2025 | hisF | -6.4 | -2.9 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b1062 | pyrC | -6.3 | -4.4 | dihydroorotase (NCBI) | compare |
| b1778 | yeaA | -6.3 | -1.8 | methionine sulfoxide reductase B (NCBI) | compare |
| b1104 | ycfL | -6.3 | -1.7 | hypothetical protein (NCBI) | compare |
| b2499 | purM | -6.2 | -3.6 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2329 | aroC | -6.1 | -4.2 | chorismate synthase (NCBI) | compare |
| b3389 | aroB | -6.1 | -14.5 | 3-dehydroquinate synthase (NCBI) | compare |
| b1686 | ydiI | -6.1 | -1.7 | hypothetical protein (NCBI) | compare |
| b0907 | serC | -6.0 | -5.5 | phosphoserine aminotransferase (NCBI) | compare |
| b0072 | leuC | -6.0 | -11.8 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b2021 | hisC | -5.9 | -4.7 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b0386 | proC | -5.8 | -5.6 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b0074 | leuA | -5.8 | -11.1 | 2-isopropylmalate synthase (NCBI) | compare |
| b3770 | ilvE | -5.7 | -10.2 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b2312 | purF | -5.6 | -5.9 | amidophosphoribosyltransferase (NCBI) | compare |
| b0071 | leuD | -5.6 | -7.4 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b2479 | gcvR | -5.5 | -3.8 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b3642 | pyrE | -5.5 | -4.2 | orotate phosphoribosyltransferase (NCBI) | compare |
| b2024 | hisA | -5.4 | -1.3 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b2209 | eco | -5.4 | -1.5 | ecotin precursor (NCBI) | compare |
| b2557 | purL | -5.4 | -12.8 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b1865 | nudB | -5.4 | -1.5 | dATP pyrophosphohydrolase (NCBI) | compare |
| b3281 | aroE | -5.4 | -15.1 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0002 | thrA | -5.3 | -11.6 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b3771 | ilvD | -5.3 | -11.0 | dihydroxy-acid dehydratase (NCBI) | compare |
| b4529 | ydbJ | -5.3 | -0.9 | hypothetical protein (NCBI) | compare |
| b4451 | ryhB | -5.2 | -1.5 | Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) | compare |
| b0004 | thrC | -5.2 | -8.1 | threonine synthase (NCBI) | compare |
| b2258 | b2258 | -5.2 | -0.8 | putative transport/receptor protein (VIMSS) | compare |
| b2020 | hisD | -5.1 | -4.7 | histidinol dehydrogenase (NCBI) | compare |
| b1103 | ycfF | -5.0 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b2818 | argA | -5.0 | -5.5 | N-acetylglutamate synthase (NCBI) | compare |
| b2597 | yfiA | -5.0 | -1.1 | cold shock protein associated with 30S ribosomal subunit (NCBI) | compare |
| b4006 | purH | -4.8 | -9.3 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b1434 | ydcN | -4.8 | -1.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1607 | ydgC | -4.7 | -1.3 | conserved inner membrane protein associated with alginate biosynthesis (NCBI) | compare |
| b1613 | manA | -4.6 | -2.0 | mannose-6-phosphate isomerase (VIMSS) | compare |
| b0908 | aroA | -4.6 | -8.5 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b1183 | umuD | -4.6 | -1.0 | DNA polymerase V, subunit D (NCBI) | compare |
| b1150 | ymfR | -4.6 | -0.7 | e14 prophage; predicted protein (NCBI) | compare |
| b1817 | manX | -4.5 | -5.3 | fused mannose-specific PTS enzymes: IIA component/IIB component (NCBI) | conserved |
| b3204 | ptsN | -4.5 | -4.3 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b2600 | tyrA | -4.5 | -5.6 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b0945 | pyrD | -4.5 | -11.6 | dihydroorotate dehydrogenase (NCBI) | compare |
| b3008 | metC | -4.4 | -7.0 | cystathionine beta-lyase (NCBI) | compare |
| b1693 | aroD | -4.4 | -5.5 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0014 | dnaK | -4.3 | -1.5 | molecular chaperone DnaK (NCBI) | compare |
| b1493 | gadB | -4.3 | -0.7 | glutamate decarboxylase B, PLP-dependent (NCBI) | compare |
| b2318 | truA | -4.2 | -3.1 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2576 | srmB | -4.2 | -2.7 | ATP-dependent RNA helicase (NCBI) | compare |
| b3939 | metB | -4.2 | -6.1 | cystathionine gamma-synthase (NCBI) | compare |
| b2026 | hisI | -4.2 | -3.5 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3957 | argE | -4.1 | -7.3 | acetylornithine deacetylase (NCBI) | compare |
| b3959 | argB | -4.1 | -5.5 | acetylglutamate kinase (RefSeq) | compare |
| b1361 | ydaW | -4.1 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b2750 | cysC | -4.0 | -4.6 | adenylylsulfate kinase (NCBI) | compare |
| b0145 | dksA | -4.0 | -4.1 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b3941 | metF | -4.0 | -5.4 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b4013 | metA | -3.9 | -3.4 | homoserine O-succinyltransferase (NCBI) | compare |
| b2939 | yqgB | -3.9 | -0.9 | predicted protein (RefSeq) | compare |
| b3368 | cysG | -3.9 | -12.2 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0033 | carB | -3.9 | -8.3 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b3183 | obgE | -3.8 | -1.2 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b2913 | serA | -3.8 | -5.8 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b3172 | argG | -3.8 | -6.8 | argininosuccinate synthase (NCBI) | compare |
| b2019 | hisG | -3.8 | -2.9 | ATP phosphoribosyltransferase (NCBI) | compare |
| b2620 | smpB | -3.7 | -1.2 | SsrA-binding protein (NCBI) | compare |
| b4538 | yoeF | -3.7 | -1.2 | hypothetical protein (RefSeq) | compare |
| b0003 | thrB | -3.7 | -5.0 | homoserine kinase (NCBI) | compare |
| b1961 | dcm | -3.6 | -1.1 | DNA cytosine methylase (NCBI) | compare |
| b0880 | cspD | -3.6 | -1.4 | cold shock protein homolog (NCBI) | compare |
| b4410 | ecnA | -3.5 | -0.8 | entericidin A membrane lipoprotein, antidote entericidin B (NCBI) | compare |
| b1819 | manZ | -3.5 | -2.8 | mannose-specific enzyme IID component of PTS (NCBI) | conserved |
| b3958 | argC | -3.4 | -6.5 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b3960 | argH | -3.4 | -6.1 | argininosuccinate lyase (NCBI) | compare |
| b2642 | yfjW | -3.4 | -0.9 | CP4-57 prophage; predicted inner membrane protein (NCBI) | compare |
| b1164 | ycgZ | -3.4 | -1.1 | hypothetical protein (NCBI) | compare |
| b0722 | sdhD | -3.3 | -3.1 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b4151 | frdD | -3.3 | -3.0 | fumarate reductase subunit D (NCBI) | compare |
| b1882 | cheY | -3.3 | -0.5 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b0113 | pdhR | -3.2 | -3.6 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b4426 | isrA | -3.2 | -1.9 | unknown RNA (NCBI) | compare |
| b1070 | flgN | -3.2 | -0.9 | export chaperone for FlgK and FlgL (NCBI) | compare |
| b3500 | gor | -3.2 | -1.4 | glutathione reductase (NCBI) | compare |
| b2410 | yfeH | -3.2 | -4.0 | predicted inner membrane protein (NCBI) | compare |
| b3761 | trpT | -3.1 | -0.9 | tRNA-Trp (NCBI) | compare |
| b3773 | ilvY | -3.1 | -5.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1269 | rluB | -3.1 | -2.9 | 23S rRNA pseudouridylate synthase (NCBI) | compare |
| b1595 | ynfL | -3.1 | -2.7 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0049 | apaH | -3.0 | -3.0 | diadenosinetetraphosphatase (NCBI) | compare |
| b0522 | purK | -3.0 | -4.6 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b1259 | yciG | -2.9 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b4503 | yafF | -2.9 | -0.7 | no description | compare |
| b3205 | yhbJ | -2.9 | -2.9 | hypothetical protein (NCBI) | compare |
| b2838 | lysA | -2.9 | -4.7 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b4676 | yoaK | -2.8 | -0.6 | expressed protein (RefSeq) | compare |
| b3870 | glnA | -2.8 | -1.9 | glutamine synthetase (NCBI) | compare |
| b0142 | folK | -2.8 | -0.4 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b1290 | sapF | -2.8 | -1.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2414 | cysK | -2.7 | -4.1 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b2599 | pheA | -2.7 | -3.4 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b2689 | yqaA | -2.7 | -1.4 | conserved inner membrane protein (NCBI) | compare |
| b1262 | trpC | -2.7 | -2.5 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b1696 | ydiP | -2.7 | -2.5 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1192 | ldcA | -2.7 | -3.7 | L,D-carboxypeptidase A (NCBI) | compare |
| b1260 | trpA | -2.7 | -2.5 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0263 | afuB | -2.7 | -2.1 | CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) | compare |
| b0200 | gmhB | -2.6 | -1.2 | hypothetical protein (NCBI) | compare |
| b3863 | polA | -2.6 | -1.0 | DNA polymerase I (NCBI) | compare |
| b2763 | cysI | -2.6 | -4.8 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b0888 | trxB | -2.6 | -3.0 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b0467 | priC | -2.6 | -3.1 | primosomal replication protein N'' (NCBI) | compare |
| b1936 | intG | -2.5 | -0.8 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b3237 | argR | -2.5 | -2.5 | arginine repressor (NCBI) | compare |
| b2340 | sixA | -2.5 | -3.5 | phosphohistidine phosphatase (NCBI) | compare |
| b1533 | ydeD | -2.5 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b0032 | carA | -2.5 | -3.5 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b1921 | fliZ | -2.5 | -2.3 | orf, hypothetical protein (VIMSS) | compare |
| b1976 | b1976 | -2.5 | -2.5 | orf, hypothetical protein (VIMSS) | compare |
| b4480 | hdfR | -2.5 | -4.1 | transcriptional regulator HdfR (NCBI) | compare |
| b1758 | b1758 | -2.5 | -0.8 | putative cytochrome oxidase (VIMSS) | compare |
| b1291 | sapD | -2.5 | -1.8 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1523 | yneG | -2.5 | -1.1 | hypothetical protein (NCBI) | compare |
| b1709 | btuD | -2.4 | -0.5 | vitamin B12-transporter ATPase (NCBI) | compare |
| b2762 | cysH | -2.4 | -4.1 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b1547 | stfQ | -2.4 | -2.0 | Qin prophage; predicted side tail fibre assembly protein (NCBI) | compare |
| b0758 | galT | -2.4 | -4.3 | galactose-1-phosphate uridylyltransferase (NCBI) | compare |
| b0542 | renD | -2.4 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b4631 | ykgQ | -2.3 | -1.0 | no description | compare |
| b3916 | pfkA | -2.3 | -1.6 | 6-phosphofructokinase (NCBI) | compare |
| b3236 | mdh | -2.3 | -3.6 | malate dehydrogenase (NCBI) | compare |
| b0167 | glnD | -2.2 | -4.0 | PII uridylyl-transferase (NCBI) | compare |
| b4701 | sokX | -2.2 | -0.5 | sok-related sRNA, function unknown (RefSeq) | compare |
| b0389 | yaiA | -2.2 | -1.3 | hypothetical protein (NCBI) | compare |
| b0564 | appY | -2.2 | -0.5 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b2764 | cysJ | -2.2 | -3.3 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2784 | relA | -2.2 | -4.5 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b2456 | cchB | -2.2 | -2.4 | predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) | compare |
| b4068 | yjcH | -2.1 | -2.8 | required for glycolate transport, with actP (from data) | compare |
| b1987 | cbl | -2.1 | -2.8 | DNA-binding transcriptional activator of cysteine biosynthesis (NCBI) | compare |
| b2501 | ppk | -2.1 | -5.7 | polyphosphate kinase (NCBI) | compare |
| b4614 | sokA | -2.1 | -2.0 | no description | compare |
| b1368 | ynaA | -2.0 | -1.4 | Rac prophage; predicted tail protein (RefSeq) | compare |
| b0460 | hha | -2.0 | -2.8 | modulator of gene expression, with H-NS (NCBI) | compare |
| b0720 | gltA | -2.0 | -2.8 | citrate synthase (NCBI) | compare |
| b3781 | trxA | -2.0 | -2.9 | thioredoxin 1 (VIMSS) | compare |
| b3162 | deaD | -2.0 | -4.4 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b0817 | mntR | -2.0 | -2.0 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b3979 | thrT | -2.0 | -0.3 | tRNA-Thr (NCBI) | compare |
| b3263 | yhdU | -1.9 | -4.5 | predicted membrane protein (NCBI) | compare |
| b4096 | phnL | -1.9 | -2.6 | carbon-phosphorus lyase complex subunit (NCBI) | compare |
| b4435 | isrC | -1.9 | -1.0 | unknown RNA (NCBI) | compare |
| b1273 | yciN | -1.9 | -1.0 | hypothetical protein (NCBI) | compare |
| b1837 | yebW | -1.9 | -2.2 | orf, hypothetical protein (VIMSS) | compare |
| b1270 | btuR | -1.9 | -1.5 | cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) | compare |
| b4146 | yjeK | -1.9 | -2.8 | predicted lysine aminomutase (NCBI) | compare |
| b4699 | fnrS | -1.9 | -0.5 | FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) | compare |
| b0630 | lipB | -1.9 | -0.8 | protein of lipoate biosynthesis (VIMSS) | compare |
| b2237 | inaA | -1.9 | -2.1 | hypothetical protein (NCBI) | compare |
| b3169 | nusA | -1.9 | -1.0 | transcription elongation factor NusA (NCBI) | compare |
| b1252 | tonB | -1.9 | -1.9 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b2518 | ndk | -1.8 | -1.9 | nucleoside diphosphate kinase (NCBI) | compare |
| b2839 | lysR | -1.8 | -2.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2935 | tktA | -1.8 | -1.3 | transketolase 1, thiamin-binding (NCBI) | compare |
| b3026 | qseC | -1.8 | -3.5 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b2266 | elaB | -1.8 | -2.0 | hypothetical protein (NCBI) | compare |
| b0520 | ylbF | -1.8 | -2.4 | hypothetical protein (NCBI) | compare |
| b0784 | moaD | -1.8 | -1.3 | molybdopterin synthase, small subunit (NCBI) | compare |
| b1730 | ydjO | -1.8 | -0.6 | predicted protein (RefSeq) | compare |
| b0249 | ykfF | -1.8 | -1.0 | CP4-6 prophage; predicted protein (NCBI) | compare |
| b4057 | yjbR | -1.8 | -2.3 | hypothetical protein (NCBI) | compare |
| b1360 | ydaV | -1.8 | -1.8 | Rac prophage; predicted DNA replication protein (NCBI) | compare |
| b1185 | dsbB | -1.7 | -2.1 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b4214 | cysQ | -1.7 | -4.1 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b0759 | galE | -1.7 | -2.7 | UDP-galactose-4-epimerase (VIMSS) | compare |
| b0075 | leuL | -1.7 | -2.8 | leu operon leader peptide (NCBI) | compare |
| b4048 | yjbM | -1.7 | -0.8 | hypothetical protein (NCBI) | compare |
| b1792 | yeaO | -1.7 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b0840 | deoR | -1.7 | -1.8 | DNA-binding transcriptional repressor (NCBI) | compare |
| b1236 | galU | -1.6 | -3.1 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b2632 | yfjP | -1.6 | -3.4 | CP4-57 prophage; predicted GTP-binding protein (NCBI) | compare |
| b3463 | ftsE | -1.6 | -3.9 | predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) | compare |
| b0617 | citD | -1.6 | -1.5 | citrate lyase, acyl carrier (gamma) subunit (NCBI) | compare |