Experiment set3S601 for Escherichia coli ECOR38

Compare to:

Bas09

200 most important genes:

  gene name fitness t score description  
HEPCGN_02315 -5.0 -1.4 MarR family transcriptional regulator compare
HEPCGN_16680 zapG -4.9 -2.8 Z-ring associated protein ZapG compare
HEPCGN_13605 pstB -4.6 -2.1 phosphate ABC transporter ATP-binding protein PstB compare
HEPCGN_02900 -4.4 -1.2 Type I toxin-antitoxin system Ibs family toxin compare
HEPCGN_08815 surA -3.9 -6.5 peptidylprolyl isomerase SurA compare
HEPCGN_22075 nuoH -3.7 -2.6 NADH-quinone oxidoreductase subunit NuoH compare
HEPCGN_13290 wecA -3.6 -2.5 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase compare
HEPCGN_01010 ubiF -3.4 -1.6 3-demethoxyubiquinol 3-hydroxylase compare
HEPCGN_24920 prmC -3.3 -3.9 peptide chain release factor N(5)-glutamine methyltransferase compare
HEPCGN_25720 sapF -3.2 -1.2 peptide ABC transporter ATP-binding protein SapF compare
HEPCGN_22000 ackA -3.2 -3.1 acetate kinase compare
HEPCGN_23880 yceD -3.2 -3.7 23S rRNA accumulation protein YceD compare
HEPCGN_06990 cyoD -3.2 -2.3 cytochrome o ubiquinol oxidase subunit III compare
HEPCGN_01305 sucA -3.1 -7.4 2-oxoglutarate dehydrogenase E1 component compare
HEPCGN_22060 nuoE -3.1 -3.1 NADH-quinone oxidoreductase subunit NuoE compare
HEPCGN_03670 -3.1 -2.1 Putative bacterial toxin ydaT compare
HEPCGN_12935 ubiE -3.0 -1.7 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE compare
HEPCGN_12915 tatA -3.0 -1.2 Sec-independent protein translocase subunit TatA compare
HEPCGN_22050 nuoB -2.9 -7.9 NADH-quinone oxidoreductase subunit NuoB compare
HEPCGN_01100 uof -2.8 -1.1 fur leader peptide compare
HEPCGN_01310 odhB -2.8 -4.6 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
HEPCGN_03710 -2.8 -1.6 Uncharacterized protein Rem compare
HEPCGN_04750 kdgA -2.7 -3.0 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase compare
HEPCGN_04685 yobI -2.7 -1.0 Uncharacterized protein YobI compare
HEPCGN_16670 degS -2.7 -1.8 outer membrane-stress sensor serine endopeptidase DegS compare
HEPCGN_20765 iscU -2.6 -1.0 Iron-sulfur cluster assembly scaffold protein IscU compare
HEPCGN_19900 recA -2.6 -4.0 recombinase RecA compare
HEPCGN_20780 hscA -2.6 -3.0 Fe-S protein assembly chaperone HscA compare
HEPCGN_22080 nuoI -2.6 -4.5 NADH-quinone oxidoreductase subunit NuoI compare
HEPCGN_13680 -2.5 -3.8 tRNA modification GTPase MnmE compare
HEPCGN_22085 nuoJ -2.5 -4.9 NADH-quinone oxidoreductase subunit J compare
HEPCGN_03765 -2.5 -2.2 lysis protein compare
HEPCGN_16345 trkA -2.5 -6.3 Trk system potassium transporter TrkA compare
HEPCGN_15950 rpe -2.4 -2.0 ribulose-phosphate 3-epimerase compare
HEPCGN_04030 fliO -2.4 -1.1 flagellar type III secretion system protein FliO compare
HEPCGN_22065 nuoF -2.4 -6.6 NADH-quinone oxidoreductase subunit NuoF compare
HEPCGN_18630 tkt -2.4 -3.8 transketolase compare
HEPCGN_14540 rfaF -2.4 -1.8 ADP-heptose--LPS heptosyltransferase RfaF compare
HEPCGN_13320 rep -2.3 -4.5 DNA helicase Rep compare
HEPCGN_24875 ychF -2.3 -2.2 redox-regulated ATPase YchF compare
HEPCGN_19505 mazE -2.3 -3.4 type II toxin-antitoxin system antitoxin MazE compare
HEPCGN_13550 atpC -2.3 -2.6 F0F1 ATP synthase subunit epsilon compare
HEPCGN_06950 clpP -2.3 -5.0 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
HEPCGN_22055 nuoC -2.2 -6.2 NADH-quinone oxidoreductase subunit C/D compare
HEPCGN_13500 mnmG -2.2 -6.4 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
HEPCGN_22100 nuoM -2.2 -6.3 NADH-quinone oxidoreductase subunit M compare
HEPCGN_25055 hns -2.2 -1.3 DNA-binding transcriptional regulator H-NS compare
HEPCGN_20125 -2.2 -1.0 hypothetical protein compare
HEPCGN_22095 nuoL -2.1 -6.9 NADH-quinone oxidoreductase subunit L compare
HEPCGN_10565 epmA -2.1 -3.0 elongation factor P--(R)-beta-lysine ligase compare
HEPCGN_22105 nuoN -2.1 -6.0 NADH-quinone oxidoreductase subunit NuoN compare
HEPCGN_01300 sdhB -2.1 -5.6 succinate dehydrogenase iron-sulfur subunit SdhB compare
HEPCGN_26420 -2.0 -2.3 Killer protein compare
HEPCGN_21760 sixA -2.0 -3.4 phosphohistidine phosphatase SixA compare
HEPCGN_08460 acnB -1.9 -4.9 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
HEPCGN_13595 pstC -1.9 -2.9 phosphate ABC transporter permease PstC compare
HEPCGN_20905 guaA -1.9 -4.4 glutamine-hydrolyzing GMP synthase compare
HEPCGN_20505 srmB -1.9 -7.4 ATP-dependent RNA helicase SrmB compare
HEPCGN_08480 aceE -1.9 -5.6 pyruvate dehydrogenase (acetyl-transferring), homodimeric type compare
HEPCGN_10460 purA -1.9 -7.8 adenylosuccinate synthase compare
HEPCGN_16660 mdh -1.9 -4.0 malate dehydrogenase compare
HEPCGN_21370 ptsI -1.8 -3.5 phosphoenolpyruvate-protein phosphotransferase PtsI compare
HEPCGN_18790 ygfB -1.8 -3.8 UPF0149 family protein YgfB compare
HEPCGN_17495 Ile2_trna -1.7 -1.1 tRNA-Ile2(cat) compare
HEPCGN_12860 trkH -1.7 -4.9 Trk system potassium transporter TrkH compare
HEPCGN_24005 bhsA -1.7 -1.2 multiple stress resistance protein BhsA compare
HEPCGN_21995 pta -1.7 -3.3 phosphate acetyltransferase compare
HEPCGN_25140 tonB -1.7 -2.7 TonB system transport protein TonB compare
HEPCGN_22070 nuoG -1.7 -5.0 NADH-quinone oxidoreductase subunit NuoG compare
HEPCGN_01285 sdhC -1.7 -4.3 succinate dehydrogenase cytochrome b556 subunit compare
HEPCGN_03320 -1.7 -1.2 Antitoxin of the YeeV-YeeU toxin-antitoxin system CP4-44 prophage compare
HEPCGN_22045 nuoA -1.6 -2.9 NADH-quinone oxidoreductase subunit NuoA compare
HEPCGN_08475 aceF -1.6 -1.4 pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase compare
HEPCGN_17060 yhbS -1.6 -3.2 Uncharacterized N-acetyltransferase YhbS compare
HEPCGN_22930 trxB -1.6 -1.8 thioredoxin-disulfide reductase compare
HEPCGN_08835 apaH -1.6 -3.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
HEPCGN_06115 mlc -1.6 -6.0 DNA-binding transcriptional repressor Mlc compare
HEPCGN_10020 rraB -1.6 -4.3 ribonuclease E inhibitor RraB compare
HEPCGN_24160 -1.6 -2.2 phage head closure protein compare
HEPCGN_21875 truA -1.6 -3.3 aspartate-semialdehyde dehydrogenase compare
HEPCGN_05060 yeaO -1.6 -1.1 Uncharacterized protein YeaO compare
HEPCGN_27010 -1.5 -2.5 phage tail protein compare
HEPCGN_06945 clpX -1.5 -3.9 ATP-dependent protease ATP-binding subunit ClpX compare
HEPCGN_19955 gshA -1.5 -5.3 glutamate--cysteine ligase compare
HEPCGN_00215 -1.5 -1.1 DNA-binding protein compare
HEPCGN_12895 rfaH -1.5 -3.1 transcription/translation regulatory transformer protein RfaH compare
HEPCGN_16490 yhdU -1.5 -0.9 Inner membrane protein YhdU compare
HEPCGN_13600 pstA -1.5 -1.7 phosphate ABC transporter permease PstA compare
HEPCGN_05480 nlpC -1.5 -1.2 putative endopeptidase NlpC compare
HEPCGN_26920 ydeI -1.5 -0.7 YdeI family stress tolerance OB fold protein compare
HEPCGN_10455 nsrR -1.5 -4.9 nitric oxide-sensing transcriptional repressor NsrR compare
HEPCGN_20250 ratA -1.5 -1.3 type II toxin-antitoxin system toxin RatA compare
HEPCGN_08665 cra -1.5 -3.8 catabolite repressor/activator compare
HEPCGN_25795 pspB -1.5 -0.9 envelope stress response membrane protein PspB compare
HEPCGN_22515 napD -1.4 -1.3 chaperone NapD compare
HEPCGN_20545 lepA -1.4 -4.8 translation elongation factor 4 compare
HEPCGN_20770 iscA -1.4 -1.7 iron-sulfur cluster assembly protein IscA compare
HEPCGN_17465 ebgR -1.4 -5.0 transcriptional regulator EbgR compare
HEPCGN_24885 ychH -1.4 -1.9 stress-induced protein YchH compare
HEPCGN_10185 chpS -1.4 -0.7 type II toxin-antitoxin system antitoxin ChpS compare
HEPCGN_07985 gmhB -1.4 -3.6 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase compare
HEPCGN_26545 ydeO -1.4 -1.0 acid stress response transcriptional regulator YdeO compare
HEPCGN_14495 rfaJ -1.4 -4.5 lipopolysaccharide 1,2-glucosyltransferase compare
HEPCGN_01315 sucC -1.4 -3.0 ADP-forming succinate--CoA ligase subunit beta compare
HEPCGN_16655 argR -1.4 -3.7 transcriptional regulator ArgR compare
HEPCGN_04725 pyk -1.4 -4.6 pyruvate kinase compare
HEPCGN_26175 ydcH -1.4 -2.5 Uncharacterized protein YdcH compare
HEPCGN_21870 usg -1.4 -3.2 aspartate-semialdehyde dehydrogenase compare
HEPCGN_21120 ypfN -1.4 -0.9 UPF0370 protein YpfN compare
HEPCGN_24065 potC -1.4 -2.7 spermidine/putrescine ABC transporter permease PotC compare
HEPCGN_12885 fre -1.3 -4.4 NAD(P)H-flavin reductase compare
HEPCGN_15355 pitA -1.3 -3.9 inorganic phosphate transporter PitA compare
HEPCGN_12340 metL -1.3 -6.9 bifunctional aspartate kinase/homoserine dehydrogenase II compare
HEPCGN_25640 lapA -1.3 -1.9 lipopolysaccharide assembly protein LapA compare
HEPCGN_24740 fadR -1.3 -2.3 fatty acid metabolism transcriptional regulator FadR compare
HEPCGN_01295 sdhA -1.3 -5.0 succinate dehydrogenase flavoprotein subunit compare
HEPCGN_24175 -1.3 -1.6 phage terminase small subunit P27 family compare
HEPCGN_06800 rsmS -1.3 -2.7 pleiotropic regulatory protein RsmS compare
HEPCGN_26580 -1.3 -1.3 fimbria/pilus periplasmic chaperone compare
HEPCGN_10095 treC -1.3 -3.8 alpha,alpha-phosphotrehalase compare
HEPCGN_08065 rof -1.3 -4.2 Rho-binding antiterminator compare
HEPCGN_13080 yigG -1.3 -0.8 Inner membrane protein YigG compare
HEPCGN_01290 sdhD -1.3 -2.8 succinate dehydrogenase membrane anchor subunit compare
HEPCGN_19860 srlR -1.2 -5.1 glucitol operon DNA-binding transcriptional repressor SrlR compare
HEPCGN_01275 gltA -1.2 -3.4 citrate synthase compare
HEPCGN_16835 kdsC -1.2 -1.6 3-deoxy-manno-octulosonate-8-phosphatase KdsC compare
HEPCGN_03705 -1.2 -0.7 protein hokC compare
HEPCGN_01320 sucD -1.2 -3.7 succinate--CoA ligase subunit alpha compare
HEPCGN_03330 yeeS -1.2 -1.0 UPF0758 protein YeeS compare
HEPCGN_25045 rssB -1.2 -4.6 two-component system response regulator RssB compare
HEPCGN_07100 -1.2 -0.6 Putative virulence protein compare
HEPCGN_17345 exuR -1.2 -2.7 transcriptional regulator ExuR compare
HEPCGN_12560 frvA -1.2 -0.5 PTS fructose transporter subunit IIA compare
HEPCGN_09500 -1.2 -1.1 Putative Se/S carrier protein-like compare
HEPCGN_02935 ibsA -1.2 -2.4 Small toxic protein IbsA compare
HEPCGN_14530 -1.1 -1.4 O-antigen ligase domain-containing protein compare
HEPCGN_03755 -1.1 -1.0 DUF1327 domain-containing protein compare
HEPCGN_03395 -1.1 -1.4 Phosphotriesterase compare
HEPCGN_14775 yiaM -1.1 -2.0 2,3-diketo-L-gulonate TRAP transporter small permease YiaM compare
HEPCGN_11370 -1.1 -1.6 ROK family protein compare
HEPCGN_04460 yecH -1.1 -2.7 Uncharacterized protein YecH compare
HEPCGN_13160 cyaY -1.1 -2.5 iron donor protein CyaY compare
HEPCGN_04610 cutC -1.1 -1.5 copper homeostasis protein CutC compare
HEPCGN_14210 ccmK -1.1 -0.7 BMC domain-containing protein compare
HEPCGN_20835 rodZ -1.1 -1.9 cytoskeleton protein RodZ compare
HEPCGN_25605 ymiA -1.1 -1.6 YmiA family putative membrane protein compare
HEPCGN_19025 -1.1 -1.0 GhoT/OrtT family toxin compare
HEPCGN_05830 ydhL -1.1 -0.9 Uncharacterized protein YdhL compare
HEPCGN_01470 pal -1.1 -2.0 peptidoglycan-associated lipoprotein Pal compare
HEPCGN_22125 elaD -1.1 -1.6 ElaD/SseL family deubiquitinase compare
HEPCGN_02320 -1.1 -3.0 hypothetical protein compare
HEPCGN_08980 espX1 -1.1 -2.3 type III secretion system effector EspX1 compare
HEPCGN_22935 lrp -1.1 -3.3 leucine-responsive transcriptional regulator Lrp compare
HEPCGN_17225 yhaB -1.1 -1.9 Uncharacterized protein YhaB compare
HEPCGN_00915 rlmH -1.1 -0.8 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
HEPCGN_18795 pepP -1.1 -2.5 Xaa-Pro aminopeptidase compare
HEPCGN_00170 -1.1 -6.6 peptidyl-arginine deiminase compare
HEPCGN_14520 rfaJ -1.1 -2.1 UDP-galactose--(galactosyl) LPS alpha1,2-galactosyltransferase compare
HEPCGN_03690 -1.1 -1.8 Tellurite resistance protein TehB compare
HEPCGN_06205 -1.1 -0.8 DUF5051 domain-containing protein compare
HEPCGN_22665 mepS -1.1 -3.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
HEPCGN_12475 pfkA -1.1 -2.8 6-phosphofructokinase compare
HEPCGN_25695 acrR -1.1 -2.4 TetR family transcriptional regulator compare
HEPCGN_15630 yrhA -1.1 -1.4 protein YrhA compare
HEPCGN_14645 mtlR -1.0 -2.9 mannitol operon repressor MtlR compare
HEPCGN_18120 neuA -1.0 -1.5 N-acylneuraminate cytidylyltransferase compare
HEPCGN_24505 -1.0 -1.5 Conserved hypothetical phage-related protein compare
HEPCGN_05580 aroD -1.0 -1.9 3-dehydroquinate dehydratase compare
HEPCGN_01060 nagC -1.0 -3.7 DNA-binding transcriptional regulator NagC compare
HEPCGN_25195 -1.0 -3.4 hypothetical protein compare
HEPCGN_22885 cspD -1.0 -1.0 cold shock-like protein CspD compare
HEPCGN_05505 ppsR -1.0 -2.9 posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR compare
HEPCGN_13250 wzxE -1.0 -3.1 lipid III flippase WzxE compare
HEPCGN_02065 ybjN -1.0 -2.8 Uncharacterized protein YbjN compare
HEPCGN_01455 tolR -1.0 -1.5 colicin uptake protein TolR compare
HEPCGN_17970 -1.0 -1.1 phosphopantetheine attachment site family protein compare
HEPCGN_17175 agaR -1.0 -3.3 aga operon transcriptional regulator AgaR compare
HEPCGN_20855 yfgM -1.0 -2.1 ancillary SecYEG translocon subunit YfgM compare
HEPCGN_04035 fliN -1.0 -1.0 flagellar motor switch protein FliN compare
HEPCGN_20875 -1.0 -1.9 Intimin ((Attaching and effacing protein) or invasin protein (SivH-like)) compare
HEPCGN_04740 zwf -1.0 -2.9 glucose-6-phosphate dehydrogenase compare
HEPCGN_01120 seqA -1.0 -1.6 replication initiation negative regulator SeqA compare
HEPCGN_22035 lrhA -0.9 -4.6 transcriptional regulator LrhA compare
HEPCGN_13995 -0.9 -1.7 Uncharacterized protein YicS compare
HEPCGN_01420 -0.9 -4.7 hypothetical protein compare
HEPCGN_02725 yehC -0.9 -1.0 putative fimbrial chaperone YehC compare
HEPCGN_16905 yhbE -0.9 -3.4 Uncharacterized inner membrane transporter YhbE compare
HEPCGN_15210 hdeB -0.9 -2.4 acid-activated periplasmic chaperone HdeB compare
HEPCGN_18390 papF -0.9 -2.2 P fimbrial tip protein PapF compare
HEPCGN_12115 Thr_trna -0.9 -0.8 tRNA-Thr(ggt) compare
HEPCGN_21200 pta -0.9 -1.7 phosphate acetyltransferase compare
HEPCGN_25930 ogt -0.9 -1.6 methylated-DNA--[protein]-cysteine S-methyltransferase compare
HEPCGN_01065 nagA -0.9 -2.8 N-acetylglucosamine-6-phosphate deacetylase compare
HEPCGN_12110 tuf -0.9 -0.5 elongation factor Tu compare
HEPCGN_26305 yncG -0.9 -1.6 Uncharacterized GST-like protein YncG compare
HEPCGN_06810 acrR -0.9 -3.2 multidrug efflux transporter transcriptional repressor AcrR compare
HEPCGN_23855 -0.9 -1.1 CopG family transcriptional regulator compare
HEPCGN_18620 speB -0.9 -2.3 agmatinase compare
HEPCGN_00885 lipB -0.9 -1.3 lipoyl(octanoyl) transferase LipB compare
HEPCGN_15660 gntR -0.9 -4.6 gluconate operon transcriptional repressor GntR compare


Specific Phenotypes

For 6 genes in this experiment

For phage Phage in Escherichia coli ECOR38

For phage Phage across organisms