Experiment set3S343 for Escherichia coli ECOR27

Compare to:

Bas21

200 most detrimental genes:

  gene name fitness t score description  
NOLOHH_03935 fimE +1.8 7.1 type 1 fimbria switch DNA invertase FimE compare
NOLOHH_17755 menI +1.5 3.2 1,4-dihydroxy-2-naphthoyl-CoA hydrolase compare
NOLOHH_12310 rpoS +1.4 7.8 RNA polymerase sigma factor RpoS compare
NOLOHH_13630 ypfN +1.3 2.1 UPF0370 protein YpfN compare
NOLOHH_03330 +1.3 1.9 T3SS effector EspX compare
NOLOHH_16405 fliZ +1.3 1.8 flagella biosynthesis regulatory protein FliZ compare
NOLOHH_14015 fryB +1.3 2.9 PTS system fructose-like EIIB component 1 compare
NOLOHH_13285 iscR +1.2 6.3 Fe-S cluster assembly transcriptional regulator IscR compare
NOLOHH_20785 ycgL +1.2 2.9 Protein YcgL compare
NOLOHH_21205 flgB +1.2 1.9 flagellar basal body rod protein FlgB compare
NOLOHH_16290 fliQ +1.2 2.3 flagellar biosynthesis protein FliQ compare
NOLOHH_24505 +1.2 3.4 type II secretion protein F compare
NOLOHH_17330 ydjA +1.1 1.5 NAD(P)H nitroreductase compare
NOLOHH_19095 narW +1.1 3.0 nitrate reductase molybdenum cofactor assembly chaperone compare
NOLOHH_16025 pocR +1.0 2.4 regulatory protein PocR compare
NOLOHH_16805 +1.0 1.7 maltose ABC transporter permease compare
NOLOHH_17805 lpp +1.0 2.7 murein lipoprotein Lpp compare
NOLOHH_17785 sufD +1.0 1.4 Fe-S cluster assembly protein SufD compare
NOLOHH_18185 ydgI +1.0 1.7 Putative arginine/ornithine antiporter compare
NOLOHH_20440 ychT +1.0 1.6 Protein YchT compare
NOLOHH_19240 potB +1.0 1.3 spermidine/putrescine ABC transporter permease compare
NOLOHH_09455 +0.9 1.6 DUF2556 domain-containing protein compare
NOLOHH_14935 rsuA +0.9 2.1 16S rRNA pseudouridine(516) synthase RsuA compare
NOLOHH_17400 ydjZ +0.9 2.0 TVP38/TMEM64 family inner membrane protein YdjZ compare
NOLOHH_13900 ypeB +0.9 3.1 Uncharacterized protein YpeB compare
NOLOHH_16195 hprR +0.9 2.4 response regulator transcription factor HprR compare
NOLOHH_17625 btuE +0.9 2.4 bifunctional thioredoxin/glutathione peroxidase compare
NOLOHH_21880 elfD +0.9 1.9 putative fimbrial chaperone protein ElfD compare
NOLOHH_23350 fimA +0.9 1.7 type 1 fimbrial protein compare
NOLOHH_17125 rnd +0.9 1.4 ribonuclease D compare
NOLOHH_20335 trpA +0.9 2.2 tryptophan synthase subunit alpha compare
NOLOHH_24810 traV +0.9 1.3 type IV conjugative transfer system lipoprotein TraV compare
NOLOHH_20005 ycjF +0.9 1.4 UPF0283 membrane protein YcjF compare
NOLOHH_21000 ldtC +0.9 2.4 L,D-transpeptidase LdtC compare
NOLOHH_23000 ea10 +0.9 1.2 Protein ea10 compare
NOLOHH_18885 ydeP +0.9 1.5 acid resistance putative oxidoreductase YdeP compare
NOLOHH_15505 parE +0.9 1.7 type II toxin-antitoxin system RelE/ParE family toxin compare
NOLOHH_19045 yddM +0.8 1.2 HigA family addiction module antitoxin compare
NOLOHH_17840 ydhU +0.8 1.9 Putative cytochrome YdhU compare
NOLOHH_22075 pflA +0.8 1.8 pyruvate formate lyase 1-activating protein compare
NOLOHH_22360 ybjM +0.8 1.8 Inner membrane protein YbjM compare
NOLOHH_20555 chaB +0.8 1.2 putative cation transport regulator ChaB compare
NOLOHH_22920 +0.8 2.0 protein ninF compare
NOLOHH_14200 sixA +0.8 1.5 phosphohistidine phosphatase SixA compare
NOLOHH_13430 yfgG +0.8 1.0 Uncharacterized protein YfgG compare
NOLOHH_17655 aroH +0.8 2.3 3-deoxy-7-phosphoheptulonate synthase AroH compare
NOLOHH_18625 ydfI +0.8 2.1 Uncharacterized oxidoreductase YdfI compare
NOLOHH_18620 ydfJ +0.8 1.6 Putative transporter YdfJ compare
NOLOHH_18820 lsrA +0.8 1.6 autoinducer 2 ABC transporter ATP-binding protein LsrA compare
NOLOHH_20670 dhaL +0.8 1.4 dihydroxyacetone kinase subunit DhaL compare
NOLOHH_20015 ycjW +0.8 1.0 Uncharacterized HTH-type transcriptional regulator YcjW compare
NOLOHH_16425 yecC +0.8 1.9 L-cystine ABC transporter ATP-binding protein YecC compare
NOLOHH_18965 ddpB +0.7 1.8 putative D,D-dipeptide transport system permease protein DdpB compare
NOLOHH_08355 rsmJ +0.7 3.4 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ compare
NOLOHH_05250 +0.7 1.1 Putative type III effector protein compare
NOLOHH_18810 lsrD +0.7 2.1 autoinducer 2 ABC transporter permease LsrD compare
NOLOHH_00720 +0.7 2.9 cruciferin compare
NOLOHH_20720 dadX +0.7 2.0 catabolic alanine racemase DadX compare
NOLOHH_24635 repL +0.7 1.4 Positive regulator of RepFIC repA1 expression compare
NOLOHH_13855 yfeK +0.7 2.7 Uncharacterized protein YfeK compare
NOLOHH_20030 pgmB +0.7 1.4 beta-phosphoglucomutase compare
NOLOHH_18305 ynfA +0.7 0.8 YnfA family protein compare
NOLOHH_12630 ygaH +0.7 1.9 L-valine transporter subunit YgaH compare
NOLOHH_16305 fliN +0.7 1.2 flagellar motor switch protein FliN compare
NOLOHH_24745 trbB +0.7 1.5 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB compare
NOLOHH_21335 mdoC +0.7 1.1 glucans biosynthesis protein MdoC compare
NOLOHH_18915 yddB +0.7 1.8 Uncharacterized protein YddB compare
NOLOHH_24470 +0.7 1.6 prepilin-type cleavage/methylation domain-containing protein compare
NOLOHH_21445 pgaA +0.7 2.3 poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA compare
NOLOHH_10285 yqiM +0.7 1.4 Protein YqiM compare
NOLOHH_16510 araF +0.7 1.8 arabinose ABC transporter substrate-binding protein AraF compare
NOLOHH_19625 +0.7 1.5 phage tail protein compare
NOLOHH_20795 ycgJ +0.7 0.8 Uncharacterized protein YcgJ compare
NOLOHH_09300 zntR +0.7 1.9 Zn(2+)-responsive transcriptional regulator compare
NOLOHH_12305 nlpD +0.7 4.1 murein hydrolase activator NlpD compare
NOLOHH_18315 rspB +0.7 1.3 Zn-dependent oxidoreductase compare
NOLOHH_02125 dinJ +0.7 1.6 type II toxin-antitoxin system antitoxin DinJ compare
NOLOHH_11185 speB +0.7 3.7 agmatinase compare
NOLOHH_15990 pduE +0.7 2.2 propanediol dehydratase small subunit PduE compare
NOLOHH_20415 oppB +0.7 1.3 oligopeptide ABC transporter permease OppB compare
NOLOHH_16315 fliL +0.7 2.1 flagellar basal body-associated protein FliL compare
NOLOHH_03860 hypT +0.7 1.8 hypochlorite stress DNA-binding transcriptional regulator HypT compare
NOLOHH_12775 +0.6 1.3 Response-reg-2 domain-containing protein compare
NOLOHH_13720 eutN +0.6 0.6 ethanolamine utilization microcompartment protein EutN compare
NOLOHH_00605 essD +0.6 2.2 phage lysis protein EssD compare
NOLOHH_18640 ydfG +0.6 0.9 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG compare
NOLOHH_16180 msrQ +0.6 1.0 protein-methionine-sulfoxide reductase heme-binding subunit MsrQ compare
NOLOHH_23655 gltL +0.6 1.1 glutamate/aspartate ABC transporter ATP-binding protein GltL compare
NOLOHH_07720 yibA +0.6 1.0 Protein YibA compare
NOLOHH_12635 ygaZ +0.6 3.6 L-valine exporter subunit YgaZ compare
NOLOHH_18100 malY +0.6 1.1 bifunctional maltose regulon transcriptional repressor/cystathionine beta-lyase MalY compare
NOLOHH_23795 cspE +0.6 2.1 transcription antiterminator/RNA stability regulator CspE compare
NOLOHH_00945 ybbC +0.6 1.5 Uncharacterized protein YbbC compare
NOLOHH_03300 fkpB +0.6 1.0 FKBP-type peptidyl-prolyl cis-trans isomerase compare
NOLOHH_05485 yjaH +0.6 3.4 Uncharacterized protein YjaH compare
NOLOHH_16975 prc +0.6 3.1 carboxy terminal-processing peptidase compare
NOLOHH_00985 fetA +0.6 2.5 iron ABC transporter ATP-binding protein FetA compare
NOLOHH_11775 yqeJ +0.6 0.9 Uncharacterized protein YqeJ compare
NOLOHH_17110 yeaY +0.6 1.5 Slp family lipoprotein YeaY compare
NOLOHH_21015 ycfJ +0.6 1.3 Uncharacterized protein YcfJ compare
NOLOHH_18235 araJ +0.6 2.0 MFS transporter compare
NOLOHH_02285 hcp1,tssD1 +0.6 0.5 type VI secretion system protein, Hcp family compare
NOLOHH_18970 ddpC +0.6 1.8 D,D-dipeptide ABC transporter permease compare
NOLOHH_15520 baeR +0.6 1.9 two-component system response regulator BaeR compare
NOLOHH_23095 ybhH +0.6 2.1 4-oxalomesaconate tautomerase compare
NOLOHH_18380 +0.6 1.3 DUF977 domain-containing protein compare
NOLOHH_09635 sspB +0.6 2.5 ClpXP protease specificity-enhancing factor compare
NOLOHH_19845 recT +0.6 0.9 recombination protein RecT compare
NOLOHH_01380 pgpA +0.6 0.8 phosphatidylglycerophosphatase A compare
NOLOHH_20500 narI +0.6 1.6 respiratory nitrate reductase subunit gamma compare
NOLOHH_20675 dhaM +0.6 1.9 dihydroxyacetone kinase phosphoryl donor subunit DhaM compare
NOLOHH_01000 cueR +0.6 1.9 Cu(I)-responsive transcriptional regulator compare
NOLOHH_13600 vapC +0.6 1.9 VapC toxin family PIN domain ribonuclease compare
NOLOHH_12710 ygaV +0.6 1.5 putative HTH-type transcriptional regulator YgaV compare
NOLOHH_14595 arnT +0.6 1.6 lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase compare
NOLOHH_21170 flgI +0.6 1.7 flagellar basal body P-ring protein FlgI compare
NOLOHH_18415 ydfU +0.6 1.8 Uncharacterized protein YdfU compare
NOLOHH_11530 yqfG +0.6 1.9 Uncharacterized protein YqfG compare
NOLOHH_16700 +0.6 1.0 putative transcriptional regulatory protein YebC compare
NOLOHH_16620 yecT +0.6 0.7 Uncharacterized protein YecT compare
NOLOHH_04470 yjfJ +0.6 1.4 Uncharacterized protein YjfJ compare
NOLOHH_23755 dacA +0.6 2.4 D-alanyl-D-alanine carboxypeptidase DacA compare
NOLOHH_01135 acrA +0.6 3.6 multidrug efflux RND transporter periplasmic adaptor subunit AcrA compare
NOLOHH_18545 +0.6 1.1 phage minor tail protein G compare
NOLOHH_20550 chaC +0.6 0.8 glutathione-specific gamma-glutamylcyclotransferase compare
NOLOHH_15215 yehW +0.6 1.3 glycine betaine ABC transporter permease YehW compare
NOLOHH_16160 mtfA +0.6 1.7 DgsA anti-repressor MtfA compare
NOLOHH_23735 rlmH +0.6 0.9 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
NOLOHH_17010 yobH +0.5 1.5 Uncharacterized protein YobH compare
NOLOHH_20205 osmB +0.5 0.8 osmotically-inducible lipoprotein OsmB compare
NOLOHH_17725 uhpC +0.5 0.6 MFS transporter compare
NOLOHH_01020 ybaQ +0.5 1.5 HigA family addiction module antitoxin compare
NOLOHH_23730 rsfS +0.5 2.2 ribosome silencing factor compare
NOLOHH_00530 +0.5 1.7 Tail completion protein Z compare
NOLOHH_17745 ydiK +0.5 1.5 AI-2E family transporter YdiK compare
NOLOHH_21400 ycdY +0.5 1.0 molecular chaperone YcdY compare
NOLOHH_06525 +0.5 1.3 DUF943 domain-containing protein compare
NOLOHH_09470 dusB +0.5 3.1 tRNA dihydrouridine synthase DusB compare
NOLOHH_18540 +0.5 1.7 Tail tube protein compare
NOLOHH_13240 hcaC +0.5 1.1 bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit compare
NOLOHH_04385 ulaF +0.5 2.0 L-ribulose-5-phosphate 4-epimerase UlaF compare
NOLOHH_19965 pgrR +0.5 1.3 DNA-binding transcriptional regulator PgrR compare
NOLOHH_06285 +0.5 1.9 hypothetical protein compare
NOLOHH_15245 yehR +0.5 1.7 Uncharacterized lipoprotein YehR compare
NOLOHH_21315 yceK +0.5 1.1 YceK/YidQ family lipoprotein compare
NOLOHH_18200 pntB +0.5 1.3 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta compare
NOLOHH_20275 yciN +0.5 1.4 Protein YciN compare
NOLOHH_19380 aldA +0.5 1.6 aldehyde dehydrogenase compare
NOLOHH_13965 yfeC +0.5 1.7 Uncharacterized protein YfeC compare
NOLOHH_01405 nrdR +0.5 1.2 transcriptional regulator NrdR compare
NOLOHH_00940 +0.5 0.7 RHS repeat protein compare
NOLOHH_05475 +0.5 1.9 zinc resistance-associated protein compare
NOLOHH_18920 pqqL +0.5 1.1 putative zinc protease PqqL compare
NOLOHH_19110 nhoA +0.5 1.3 N-hydroxyarylamine O-acetyltransferase compare
NOLOHH_19695 +0.5 1.7 terminase small subunit compare
NOLOHH_17280 ydjK +0.5 1.6 Putative metabolite transport protein YdjK compare
NOLOHH_09045 yhfA +0.5 1.4 OsmC family protein compare
NOLOHH_15615 dcd +0.5 1.4 dCTP deaminase compare
NOLOHH_11480 sdhE +0.5 0.6 FAD assembly factor SdhE compare
NOLOHH_17135 yeaW +0.5 1.2 carnitine monooxygenase subunit YeaW compare
NOLOHH_24660 +0.5 1.7 Hok/Gef family protein compare
NOLOHH_19585 gpA1 +0.5 0.6 phage tail protein compare
NOLOHH_22780 ybhB +0.5 2.5 kinase inhibitor compare
NOLOHH_21200 flgC +0.5 0.7 flagellar basal body rod protein FlgC compare
NOLOHH_19255 ydcR +0.5 1.0 Uncharacterized HTH-type transcriptional regulator YdcR compare
NOLOHH_20715 +0.5 1.1 hypothetical protein compare
NOLOHH_15470 gatB +0.5 1.6 PTS galactitol transporter subunit IIB compare
NOLOHH_19035 maeA +0.5 1.2 malate dehydrogenase compare
NOLOHH_16520 araH +0.5 2.0 arabinose ABC transporter permease AraH compare
NOLOHH_00675 +0.5 1.9 regulator compare
NOLOHH_22980 +0.5 1.5 hypothetical protein compare
NOLOHH_05165 +0.5 1.6 hypothetical protein compare
NOLOHH_22305 rlmC +0.5 1.8 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC compare
NOLOHH_16320 fliK +0.5 2.1 flagellar hook length control protein FliK compare
NOLOHH_16965 msrC +0.5 2.9 L-methionine (R)-S-oxide reductase compare
NOLOHH_12725 csiR +0.5 2.3 DNA-binding transcriptional regulator CsiR compare
NOLOHH_05425 yjaB +0.5 1.9 acetyltransferase compare
NOLOHH_23175 ybgS +0.5 2.2 Uncharacterized protein YbgS compare
NOLOHH_18760 sad +0.5 1.9 succinate-semialdehyde dehydrogenase compare
NOLOHH_15515 yegP +0.5 1.1 UPF0339 protein YegP compare
NOLOHH_13850 cysM +0.5 1.3 cysteine synthase B compare
NOLOHH_21530 rutD +0.5 1.3 pyrimidine utilization protein D compare
NOLOHH_01505 +0.5 1.1 hypothetical protein compare
NOLOHH_24295 +0.5 1.0 YffA compare
NOLOHH_23165 gpmA +0.5 1.3 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
NOLOHH_01940 aRA1 +0.5 1.6 aldo/keto reductase compare
NOLOHH_11915 ygdB +0.5 2.3 DUF2509 domain-containing protein compare
NOLOHH_16310 fliM +0.5 1.0 flagellar motor switch protein FliM compare
NOLOHH_19105 yddE +0.5 1.6 PhzF family isomerase compare
NOLOHH_14010 glk +0.5 1.7 glucokinase compare
NOLOHH_05850 +0.5 1.6 DsORF-f3 compare
NOLOHH_16230 dcm +0.5 1.2 DNA-cytosine methyltransferase compare
NOLOHH_00320 +0.5 1.6 hypothetical protein compare
NOLOHH_19570 sitB +0.5 1.4 iron/manganese ABC transporter ATP-binding protein SitB compare
NOLOHH_22985 +0.5 0.7 antitermination protein N compare
NOLOHH_16970 proQ +0.5 1.5 RNA chaperone ProQ compare
NOLOHH_18980 ddpF +0.4 1.4 putative D,D-dipeptide transport ATP-binding protein DdpF compare
NOLOHH_19100 narI +0.4 0.5 respiratory nitrate reductase subunit gamma compare
NOLOHH_19370 cybB +0.4 1.2 cytochrome b561 compare
NOLOHH_17425 astA +0.4 1.0 arginine N-succinyltransferase compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECOR27 in phage experiments

For phage Phage across organisms