Experiment set3S257 for Escherichia coli ECRC98

Compare to:

Control_ECRC98_WM

200 most important genes:

  gene name fitness t score description  
JDDGAC_25875 purC -7.5 -4.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
JDDGAC_14325 leuD -7.0 -4.8 3-isopropylmalate dehydratase small subunit compare
JDDGAC_17290 metF -6.8 -12.3 methylenetetrahydrofolate reductase compare
JDDGAC_16900 metA -6.6 -4.6 homoserine O-succinyltransferase compare
JDDGAC_14700 thrB -6.5 -8.2 homoserine kinase compare
JDDGAC_11485 purE -6.4 -3.7 N5-carboxyaminoimidazole ribonucleotide mutase compare
JDDGAC_14795 serB -6.1 -4.2 phosphoserine phosphatase compare
JDDGAC_28540 rfbE -6.0 -2.5 GDP-perosamine synthase RfbE/PerA compare
JDDGAC_24895 -6.0 -1.4 Leader peptide of chorismate mutase-P-prephenate dehydratase compare
JDDGAC_24115 cysC -5.9 -12.0 Adenylyl-sulfate kinase compare
JDDGAC_16935 purH -5.9 -17.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
JDDGAC_05220 trpA -5.8 -3.1 tryptophan synthase subunit alpha compare
JDDGAC_14710 thrL -5.8 -3.1 thr operon leader peptide compare
JDDGAC_26575 aroC -5.8 -3.8 chorismate synthase compare
JDDGAC_14320 leuC1 -5.7 -14.4 3-isopropylmalate dehydratase large subunit 1 compare
JDDGAC_13010 -5.6 -1.3 Phage-associated protein compare
JDDGAC_05205 trpD -5.5 -3.8 bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD compare
JDDGAC_14315 leuB -5.4 -14.5 3-isopropylmalate dehydrogenase compare
JDDGAC_27740 -5.4 -1.3 regulator compare
JDDGAC_25755 purM -5.4 -11.8 Phosphoribosylformylglycinamidine cyclo-ligase compare
JDDGAC_24890 pheA -5.4 -12.0 bifunctional chorismate mutase/prephenate dehydratase compare
JDDGAC_20745 aroB -5.3 -3.7 3-dehydroquinate synthase compare
JDDGAC_09385 lrp -5.3 -3.7 leucine-responsive transcriptional regulator Lrp compare
JDDGAC_26675 purF -5.2 -11.1 amidophosphoribosyltransferase compare
JDDGAC_10355 acrZ -5.2 -1.2 multidrug efflux pump accessory protein AcrZ compare
JDDGAC_16940 purD -5.1 -7.9 Phosphoribosylamine--glycine ligase compare
JDDGAC_28445 wcaE -5.1 -2.1 colanic acid biosynthesis glycosyltransferase WcaE compare
JDDGAC_09100 serC -5.1 -9.6 3-phosphoserine/phosphohydroxythreonine transaminase compare
JDDGAC_25435 guaB -5.0 -6.0 IMP dehydrogenase compare
JDDGAC_18265 ilvE -5.0 -12.7 branched-chain-amino-acid transaminase compare
JDDGAC_13940 dksA -5.0 -8.9 RNA polymerase-binding protein DksA compare
JDDGAC_18260 ilvD -5.0 -14.5 dihydroxy-acid dehydratase compare
JDDGAC_24045 cysH -4.9 -7.9 phosphoadenosine phosphosulfate reductase compare
JDDGAC_17300 metB -4.9 -9.8 cystathionine gamma-synthase compare
JDDGAC_22595 metC -4.9 -10.9 cystathionine beta-lyase compare
JDDGAC_23565 -4.9 -1.2 hypothetical protein compare
JDDGAC_24035 cysJ -4.8 -11.5 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit compare
JDDGAC_21580 lptC -4.8 -1.5 LPS export ABC transporter periplasmic protein LptC compare
JDDGAC_27425 yeiL -4.8 -1.1 Regulatory protein YeiL compare
JDDGAC_25135 purL -4.8 -18.7 phosphoribosylformylglycinamidine synthase compare
JDDGAC_15675 cysQ -4.7 -7.8 3'(2'),5'-bisphosphate nucleotidase CysQ compare
JDDGAC_14705 thrA -4.7 -18.0 bifunctional aspartate kinase/homoserine dehydrogenase I compare
JDDGAC_25750 purN -4.6 -7.3 phosphoribosylglycinamide formyltransferase compare
JDDGAC_11450 fimA -4.6 -1.9 type 1 fimbrial major subunit FimA compare
JDDGAC_06430 -4.6 -1.1 phage tail protein compare
JDDGAC_19185 rpoZ -4.5 -1.1 DNA-directed RNA polymerase subunit omega compare
JDDGAC_18255 ilvA -4.5 -9.5 threonine ammonia-lyase, biosynthetic compare
JDDGAC_09095 aroA -4.5 -16.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
JDDGAC_23490 ygeN -4.5 -2.4 Putative uncharacterized protein YgeN compare
JDDGAC_10575 odhB -4.5 -2.6 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase compare
JDDGAC_25690 -4.5 -2.1 acyltransferase compare
JDDGAC_09920 espX2 -4.4 -1.8 type III secretion system effector EspX2 compare
JDDGAC_24040 cysI -4.4 -8.2 assimilatory sulfite reductase (NADPH) hemoprotein subunit compare
JDDGAC_14695 thrC -4.3 -4.3 threonine synthase compare
JDDGAC_23100 serA -4.3 -8.0 phosphoglycerate dehydrogenase compare
JDDGAC_18245 ilvC -4.2 -11.6 ketol-acid reductoisomerase compare
JDDGAC_14075 acnB -4.1 -2.1 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase compare
JDDGAC_15900 miaA -4.0 -1.9 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
JDDGAC_15870 purA -3.9 -2.4 adenylosuccinate synthase compare
JDDGAC_06300 minD -3.9 -1.5 septum site-determining protein MinD compare
JDDGAC_03705 fimA -3.9 -2.2 type 1 fimbrial major subunit FimA compare
JDDGAC_00935 yebF -3.8 -1.3 Protein YebF compare
JDDGAC_11490 purK -3.8 -5.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
JDDGAC_05215 trpB -3.8 -3.7 tryptophan synthase subunit beta compare
JDDGAC_04780 ogt -3.7 -1.8 methylated-DNA--[protein]-cysteine S-methyltransferase compare
JDDGAC_19070 escG -3.6 -1.2 type III secretion system LEE needle protein cochaperone EscG compare
JDDGAC_10465 tolA -3.6 -2.3 cell envelope integrity protein TolA compare
JDDGAC_03730 ydeQ -3.6 -1.2 Uncharacterized fimbrial-like protein YdeQ compare
JDDGAC_10205 -3.6 -1.2 Putative bacteriophage protein (Gene 65) compare
JDDGAC_21505 gltD -3.6 -8.6 glutamate synthase subunit GltD compare
JDDGAC_01425 nudG -3.6 -2.1 CTP pyrophosphohydrolase compare
JDDGAC_14440 apaH -3.5 -2.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH compare
JDDGAC_28520 wcaA -3.5 -1.9 glycosyl transferase compare
JDDGAC_24885 tyrA -3.4 -9.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
JDDGAC_22870 rdgB -3.4 -3.0 XTP/dITP diphosphatase compare
JDDGAC_21715 argG -3.4 -8.3 argininosuccinate synthase compare
JDDGAC_05200 trpE -3.4 -6.9 anthranilate synthase component I compare
JDDGAC_12265 proC -3.4 -2.3 pyrroline-5-carboxylate reductase compare
JDDGAC_01040 prc -3.3 -8.8 carboxy terminal-processing peptidase compare
JDDGAC_05210 trpCF -3.3 -5.9 bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF compare
JDDGAC_25440 guaA -3.3 -2.1 glutamine-hydrolyzing GMP synthase compare
JDDGAC_22885 yggS -3.3 -5.9 pyridoxal phosphate homeostasis protein compare
JDDGAC_00825 nudB -3.2 -1.1 dihydroneopterin triphosphate diphosphatase compare
JDDGAC_18250 ilvY -3.2 -6.1 HTH-type transcriptional activator IlvY compare
JDDGAC_03725 ydeR -3.2 -2.5 Uncharacterized fimbrial-like protein YdeR compare
JDDGAC_30055 yubL -3.2 -1.7 UPF0401 protein YubL compare
JDDGAC_06305 minE -3.2 -1.1 cell division topological specificity factor MinE compare
JDDGAC_14535 carB -3.1 -11.3 carbamoyl-phosphate synthase large subunit compare
JDDGAC_13250 -3.1 -2.0 XRE family transcriptional regulator compare
JDDGAC_10470 tolR -3.0 -3.8 colicin uptake protein TolR compare
JDDGAC_23430 escR -3.0 -2.1 EscR/YscR/HrcR family type III secretion system export apparatus protein compare
JDDGAC_21185 aroE -3.0 -4.4 shikimate dehydrogenase compare
JDDGAC_24735 rrrD -2.9 -1.0 lysozyme compare
JDDGAC_00920 kdgA -2.9 -2.0 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase compare
JDDGAC_14310 -2.9 -7.3 2-isopropylmalate synthase compare
JDDGAC_06130 hemA -2.9 -4.4 glutamyl-tRNA reductase compare
JDDGAC_25045 rseA -2.8 -3.5 anti-sigma-E factor RseA compare
JDDGAC_19320 rfaF -2.8 -1.6 ADP-heptose--LPS heptosyltransferase RfaF compare
JDDGAC_06700 -2.8 -1.9 DUF4222 domain-containing protein compare
JDDGAC_21510 gltB -2.8 -12.4 glutamate synthase large subunit compare
JDDGAC_05985 galU -2.8 -3.5 UTP--glucose-1-phosphate uridylyltransferase GalU compare
JDDGAC_01815 ydiH -2.8 -1.8 Uncharacterized protein YdiH compare
JDDGAC_14420 surA -2.8 -2.7 peptidylprolyl isomerase SurA compare
JDDGAC_03640 uxaB -2.7 -3.6 tagaturonate reductase compare
JDDGAC_18215 trxA -2.7 -1.6 thioredoxin TrxA compare
JDDGAC_17200 argH -2.7 -7.8 argininosuccinate lyase compare
JDDGAC_18405 mnmG -2.7 -3.3 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG compare
JDDGAC_17210 argC -2.6 -4.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
JDDGAC_28605 hisA -2.6 -2.1 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase compare
JDDGAC_28620 hisC -2.6 -6.1 histidinol-phosphate transaminase compare
JDDGAC_29980 sopA -2.5 -0.8 plasmid-partitioning protein SopA compare
JDDGAC_25065 lepA -2.5 -2.5 translation elongation factor 4 compare
JDDGAC_15475 argF -2.5 -6.8 ornithine carbamoyltransferase compare
JDDGAC_06785 nleL -2.5 -1.7 type III secretion system effector E3 ubiquitin ligase NleL compare
JDDGAC_05850 -2.5 -1.8 hypothetical protein compare
JDDGAC_20810 cysG -2.4 -6.6 siroheme synthase CysG compare
JDDGAC_06555 ybcO -2.4 -1.0 Putative nuclease YbcO compare
JDDGAC_26745 yfcD -2.3 -1.9 NUDIX hydrolase YfcD compare
JDDGAC_28130 fimA -2.3 -2.5 Uncharacterized fimbrial-like protein YehD compare
JDDGAC_04170 ydcA -2.3 -2.3 Uncharacterized protein YdcA compare
JDDGAC_24160 rpoS -2.3 -10.9 RNA polymerase sigma factor RpoS compare
JDDGAC_21770 nlpI -2.3 -7.7 lipoprotein NlpI compare
JDDGAC_17735 glnG -2.3 -1.2 nitrogen regulation protein NR(I) compare
JDDGAC_10390 gpmA -2.3 -4.9 2,3-diphosphoglycerate-dependent phosphoglycerate mutase compare
JDDGAC_10275 -2.3 -1.4 DUF1382 domain-containing protein compare
JDDGAC_04365 -2.2 -0.9 Putative phage tail component compare
JDDGAC_13300 proB -2.2 -3.5 Glutamate 5-kinase compare
JDDGAC_13640 gmhB -2.2 -1.8 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase compare
JDDGAC_14540 carA -2.2 -5.2 carbamoyl phosphate synthase small subunit compare
JDDGAC_13175 rzpD -2.2 -1.0 prophage endopeptidase RzpD compare
JDDGAC_00770 cutC -2.1 -1.9 copper homeostasis protein CutC compare
JDDGAC_26670 cvpA -2.1 -3.2 colicin V production protein compare
JDDGAC_06120 prmC -2.1 -1.5 peptide chain release factor N(5)-glutamine methyltransferase compare
JDDGAC_08035 lolD -2.1 -1.8 lipoprotein-releasing system ATP-binding protein LolD compare
JDDGAC_19635 cspA -2.0 -1.2 Major cold shock protein compare
JDDGAC_00545 marR -2.0 -1.6 MarR family transcriptional regulator compare
JDDGAC_18600 -2.0 -1.2 hypothetical protein compare
JDDGAC_03670 lsrC -2.0 -1.6 autoinducer 2 ABC transporter permease LsrC compare
JDDGAC_04240 ynbB -2.0 -3.7 Uncharacterized protein YnbB compare
JDDGAC_28610 hisH -2.0 -2.5 imidazole glycerol phosphate synthase subunit HisH compare
JDDGAC_10810 nagB -2.0 -3.5 glucosamine-6-phosphate deaminase compare
JDDGAC_02145 rsxA -2.0 -1.1 electron transport complex subunit RsxA compare
JDDGAC_11975 -1.9 -2.8 Lon protease compare
JDDGAC_14270 rsmH -1.9 -1.2 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH compare
JDDGAC_22140 yqiM -1.9 -0.7 Protein YqiM compare
JDDGAC_01695 ydiV -1.9 -1.8 anti-FlhDC factor compare
JDDGAC_28625 hisD -1.8 -5.5 Histidinol dehydrogenase compare
JDDGAC_04825 frsA -1.8 -2.0 alpha/beta hydrolase compare
JDDGAC_27410 psuK -1.8 -1.0 pseudouridine kinase compare
JDDGAC_05670 gp36 -1.8 -1.7 Bacteriophage Mu, Gp36 compare
JDDGAC_05050 acrR -1.8 -1.6 TetR family transcriptional regulator compare
JDDGAC_28595 hisIE -1.8 -1.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE compare
JDDGAC_18945 grlA -1.8 -1.4 type III secretion system LEE transcriptional regulator GrlA compare
JDDGAC_00910 zwf -1.8 -1.4 glucose-6-phosphate dehydrogenase compare
JDDGAC_01475 xthA -1.8 -1.9 exodeoxyribonuclease III compare
JDDGAC_05950 -1.8 -1.2 hypothetical protein compare
JDDGAC_09810 mntR -1.7 -1.8 manganese-binding transcriptional regulator MntR compare
JDDGAC_13295 proA -1.7 -6.1 glutamate-5-semialdehyde dehydrogenase compare
JDDGAC_20840 -1.7 -1.2 Uncharacterized protein YhfG compare
JDDGAC_26150 cysK -1.7 -5.7 cysteine synthase A compare
JDDGAC_04055 potB -1.7 -2.9 spermidine/putrescine ABC transporter permease compare
JDDGAC_13015 -1.7 -1.6 Phage-associated protein compare
JDDGAC_25315 hscA -1.7 -0.8 Fe-S protein assembly chaperone HscA compare
JDDGAC_05645 -1.7 -1.4 tRNA-Xxx compare
JDDGAC_21780 deaD -1.7 -3.3 ATP-dependent RNA helicase DeaD compare
JDDGAC_14305 leuL -1.7 -2.6 leu operon leader peptide compare
JDDGAC_17215 argE -1.7 -7.5 acetylornithine deacetylase compare
JDDGAC_28590 wzzB -1.7 -5.6 LPS O-antigen chain length determinant protein WzzB compare
JDDGAC_24645 -1.7 -1.3 DNA-binding protein compare
JDDGAC_27045 -1.6 -0.7 hypothetical protein compare
JDDGAC_10165 -1.6 -1.4 DNA breaking-rejoining protein compare
JDDGAC_17795 dsbA -1.6 -3.0 thiol:disulfide interchange protein DsbA compare
JDDGAC_08995 aspC -1.6 -1.9 aspartate transaminase compare
JDDGAC_01035 proQ -1.6 -3.1 RNA chaperone ProQ compare
JDDGAC_25415 bamB -1.6 -3.3 outer membrane protein assembly factor BamB compare
JDDGAC_20530 glgA -1.6 -7.1 glycogen synthase GlgA compare
JDDGAC_11240 fepG -1.6 -2.1 iron-enterobactin ABC transporter permease compare
JDDGAC_00840 ruvC -1.6 -1.9 crossover junction endodeoxyribonuclease RuvC compare
JDDGAC_03535 ydeJ -1.6 -2.3 2-oxo-tetronate isomerase compare
JDDGAC_06890 -1.6 -0.7 HNH endonuclease compare
JDDGAC_26485 Arg_trna -1.6 -2.3 tRNA-Arg(cct) compare
JDDGAC_10570 sucC -1.6 -2.4 ADP-forming succinate--CoA ligase subunit beta compare
JDDGAC_02120 rsxE -1.5 -2.8 electron transport complex subunit RsxE compare
JDDGAC_06180 -1.5 -1.8 PTS-dependent dihydroxyacetone kinase compare
JDDGAC_23570 yqeH -1.5 -0.8 Uncharacterized protein YqeH compare
JDDGAC_07485 csgC -1.5 -1.4 curli assembly protein CsgC compare
JDDGAC_18275 ilvG -1.5 -7.3 acetolactate synthase 2 catalytic subunit compare
JDDGAC_02135 rsxC -1.5 -3.0 electron transport complex subunit RsxC compare
JDDGAC_17730 glnL -1.5 -2.5 nitrogen regulation protein NR(II) compare
JDDGAC_28175 -1.5 -1.0 transcription factor compare
JDDGAC_11260 ybdZ -1.5 -0.7 Enterobactin biosynthesis protein YbdZ compare
JDDGAC_07530 ycdY -1.5 -1.6 molecular chaperone YcdY compare
JDDGAC_06165 ychF -1.5 -1.5 redox-regulated ATPase YchF compare
JDDGAC_16510 soxS_A12S -1.5 -1.8 regulatory protein SoxS compare
JDDGAC_14285 fruL -1.5 -1.2 Putative fruR/shl operon leader peptide compare
JDDGAC_03880 yddG -1.5 -1.2 aromatic amino acid efflux DMT transporter YddG compare
JDDGAC_04850 tyrR -1.5 -1.0 transcriptional regulator TyrR compare
JDDGAC_15525 mgtL -1.5 -1.0 mgtA leader peptide compare
JDDGAC_11375 -1.5 -0.8 hypothetical protein compare
JDDGAC_13950 pcnB -1.4 -2.4 polynucleotide adenylyltransferase PcnB compare


Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in no phage control experiments

For no phage control No phage across organisms