Experiment set3S239 for Escherichia coli ECRC98

200 most important genes:

gene	name	fitness	t score	description
JDDGAC_13185		-5.5	-3.2	phage holin, lambda family
JDDGAC_27740		-4.6	-1.6	regulator
JDDGAC_23565		-4.4	-1.6	hypothetical protein
JDDGAC_08750		-4.2	-3.0	cell division inhibition protein DicB
JDDGAC_01065	yebO	-3.7	-1.3	Uncharacterized protein YebO
JDDGAC_04410		-3.7	-1.3	Tail completion protein Z
JDDGAC_25690		-3.6	-2.5	acyltransferase
JDDGAC_03210		-3.5	-1.2	hypothetical protein
JDDGAC_10575	odhB	-3.5	-2.4	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase
JDDGAC_00750	flhe	-3.3	-1.8	flagellar protein FlhE
JDDGAC_06760		-3.2	-1.6	Mutator family transposase
JDDGAC_01680	btuE	-3.2	-2.8	bifunctional thioredoxin/glutathione peroxidase
JDDGAC_14435	apaG	-3.2	-1.6	Co2+/Mg2+ efflux protein ApaG
JDDGAC_11280	hokE	-2.9	-2.2	type I toxin-antitoxin system toxin HokE
JDDGAC_04595		-2.8	-1.8	DUF551 domain-containing protein
JDDGAC_05525		-2.8	-1.0	host nuclease inhibitor protein
JDDGAC_14440	apaH	-2.7	-1.8	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH
JDDGAC_06265	ycgN	-2.7	-1.8	YcgN family cysteine cluster protein
JDDGAC_19185	rpoZ	-2.6	-1.3	DNA-directed RNA polymerase subunit omega
JDDGAC_07730	terB	-2.5	-3.4	Tellurium resistance protein TerB
JDDGAC_25440	guaA	-2.5	-1.7	glutamine-hydrolyzing GMP synthase
JDDGAC_05255		-2.5	-1.2	hypothetical protein
JDDGAC_14760	trpR	-2.4	-1.5	trp operon repressor
JDDGAC_17455	pfkA	-2.4	-3.8	6-phosphofructokinase
JDDGAC_00970	holE	-2.4	-2.0	DNA polymerase III subunit theta
JDDGAC_10070	nleB2	-2.4	-1.9	type III secretion system effector arginine glycosyltransferase NleB2
JDDGAC_03730	ydeQ	-2.4	-1.2	Uncharacterized fimbrial-like protein YdeQ
JDDGAC_13250		-2.3	-2.1	XRE family transcriptional regulator
JDDGAC_29975	sopA	-2.3	-3.9	plasmid-partitioning protein SopA
JDDGAC_05530		-2.2	-1.9	hypothetical protein
JDDGAC_27425	yeiL	-2.2	-1.1	Regulatory protein YeiL
JDDGAC_07260	yceD	-2.2	-1.5	23S rRNA accumulation protein YceD
JDDGAC_27195		-2.2	-1.6	hypothetical protein
JDDGAC_08705		-2.0	-1.4	Rha family transcriptional regulator
JDDGAC_27895		-2.0	-1.8	recombinase RecA
JDDGAC_05050	acrR	-2.0	-1.7	TetR family transcriptional regulator
JDDGAC_00155	hprS	-2.0	-1.9	two-component system sensor histidine kinase HprS
JDDGAC_28445	wcaE	-2.0	-1.3	colanic acid biosynthesis glycosyltransferase WcaE
JDDGAC_14625	nhaA	-2.0	-8.8	Na+/H+ antiporter NhaA
JDDGAC_22140	yqiM	-1.9	-1.3	Protein YqiM
JDDGAC_23140	ygfB	-1.9	-2.2	UPF0149 family protein YgfB
JDDGAC_14420	surA	-1.9	-2.8	peptidylprolyl isomerase SurA
JDDGAC_06520	bor	-1.9	-0.9	serum resistance lipoprotein Bor
JDDGAC_03885	ompC2	-1.9	-2.8	Outer membrane porin C 2
JDDGAC_10355	acrZ	-1.9	-1.1	multidrug efflux pump accessory protein AcrZ
JDDGAC_26805	nuoA	-1.9	-2.2	NADH-quinone oxidoreductase subunit NuoA
JDDGAC_08180	efeB	-1.9	-2.9	iron uptake transporter deferrochelatase/peroxidase subunit
JDDGAC_03800	dosP	-1.8	-1.5	oxygen-sensing cyclic-di-GMP phosphodiesterase
JDDGAC_12935		-1.8	-1.7	hypothetical protein
JDDGAC_26340	ypdK	-1.8	-1.1	membrane protein YpdK
JDDGAC_10290		-1.7	-3.5	hypothetical protein
JDDGAC_25065	lepA	-1.7	-2.3	translation elongation factor 4
JDDGAC_05870		-1.7	-3.5	exonuclease
JDDGAC_27715	bet	-1.7	-1.7	phage recombination protein Bet
JDDGAC_21580	lptC	-1.7	-2.6	LPS export ABC transporter periplasmic protein LptC
JDDGAC_26820	nuoE	-1.7	-1.7	NADH-quinone oxidoreductase subunit NuoE
JDDGAC_18590	tnaC	-1.7	-1.4	tryptophanase leader peptide
JDDGAC_21325	yhdT	-1.7	-1.8	Uncharacterized membrane protein YhdT
JDDGAC_05790	hokD1	-1.7	-1.3	Protein HokD
JDDGAC_07530	ycdY	-1.6	-1.8	molecular chaperone YcdY
JDDGAC_06690		-1.6	-2.2	hypothetical protein
JDDGAC_12265	proC	-1.6	-2.1	pyrroline-5-carboxylate reductase
JDDGAC_04940	pspD	-1.5	-0.9	phage shock protein PspD
JDDGAC_12090	pgpA	-1.5	-1.6	phosphatidylglycerophosphatase A
JDDGAC_18405	mnmG	-1.5	-2.5	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG
JDDGAC_05105	lapA	-1.5	-1.4	lipopolysaccharide assembly protein LapA
JDDGAC_02200	lacZ	-1.5	-1.5	Beta-galactosidase/beta-glucuronidase
JDDGAC_22880	yggT	-1.5	-1.0	osmotic shock tolerance protein YggT
JDDGAC_00890	lpxM	-1.5	-3.1	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase
JDDGAC_02275	ydgH	-1.5	-2.1	DUF1471 domain-containing protein
JDDGAC_02140	rsxB	-1.5	-1.3	electron transport complex subunit RsxB
JDDGAC_03670	lsrC	-1.5	-1.1	autoinducer 2 ABC transporter permease LsrC
JDDGAC_15050		-1.5	-1.3	Putative transposase, YhgA-like
JDDGAC_17715	typA	-1.5	-8.2	ribosome-dependent GTPase TypA
JDDGAC_20700	igaA	-1.5	-1.8	intracellular growth attenuator protein IgaA
JDDGAC_11580	allA	-1.5	-1.6	ureidoglycolate lyase
JDDGAC_11975		-1.4	-2.3	Lon protease
JDDGAC_05245	espM1	-1.4	-1.2	T3SS effector guanine nucleotide exchange factor EspM1
JDDGAC_01205	dmlR	-1.4	-1.4	DNA-binding transcriptional regulator DmlR
JDDGAC_27730		-1.4	-2.5	SIR2-like domain-containing protein
JDDGAC_03845	sra	-1.4	-1.9	stationary-phase-induced ribosome-associated protein
JDDGAC_25435	guaB	-1.4	-3.7	IMP dehydrogenase
JDDGAC_04080	hicA	-1.4	-1.0	type II toxin-antitoxin system mRNA interferase toxin HicA
JDDGAC_15870	purA	-1.4	-2.8	adenylosuccinate synthase
JDDGAC_06295	minC	-1.4	-1.2	septum site-determining protein MinC
JDDGAC_06145	prs	-1.4	-1.2	ribose-phosphate diphosphokinase
JDDGAC_01505	spy	-1.4	-1.7	ATP-independent periplasmic protein-refolding chaperone Spy
JDDGAC_06645		-1.4	-1.5	hypothetical protein
JDDGAC_01750		-1.3	-1.9	hypothetical protein
JDDGAC_23180	yqfB	-1.3	-2.8	N(4)-acetylcytidine aminohydrolase
JDDGAC_11390	tnp-ISAs1	-1.3	-1.6	ISAs1 family transposase
JDDGAC_01850	sufE	-1.3	-1.9	cysteine desulfuration protein SufE
JDDGAC_28465	gmm	-1.3	-2.1	GDP-mannose mannosyl hydrolase
JDDGAC_28240	gatB	-1.3	-1.9	PTS galactitol transporter subunit IIB
JDDGAC_27770	ybcN	-1.3	-2.4	DNA base-flipping protein YbcN
JDDGAC_08070	fabG	-1.3	-2.3	3-oxoacyl-ACP reductase
JDDGAC_05275		-1.3	-1.3	Mutator family transposase
JDDGAC_05585		-1.3	-1.3	hypothetical protein
JDDGAC_19040	sepL	-1.3	-1.0	type III secretion system LEE gatekeeper SepL
JDDGAC_26485	Arg_trna	-1.3	-2.1	tRNA-Arg(cct)
JDDGAC_05730	ymfQ	-1.3	-1.0	Bacteriophage Mu-like, Gp48
JDDGAC_11260	ybdZ	-1.3	-0.8	Enterobactin biosynthesis protein YbdZ
JDDGAC_25410	yfgM	-1.3	-1.0	ancillary SecYEG translocon subunit YfgM
JDDGAC_10765	ybfE	-1.2	-2.4	LexA regulated protein
JDDGAC_05785		-1.2	-0.8	Hypothetical rem protein
JDDGAC_14430	rsmA	-1.2	-1.5	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA
JDDGAC_13015		-1.2	-2.0	Phage-associated protein
JDDGAC_06530		-1.2	-1.4	lysozyme
JDDGAC_28830		-1.2	-2.6	Endonuclease
JDDGAC_14595	fimA	-1.2	-1.9	fimbrial protein
JDDGAC_08665		-1.2	-0.9	Hok/gef family
JDDGAC_02145	rsxA	-1.2	-1.0	electron transport complex subunit RsxA
JDDGAC_06345	tfaX	-1.2	-2.0	Protein TfaX
JDDGAC_03795	dosP	-1.2	-1.2	oxygen-sensing cyclic-di-GMP phosphodiesterase
JDDGAC_18070	cyaA	-1.2	-1.3	class I adenylate cyclase
JDDGAC_07275	rluC	-1.2	-2.5	23S rRNA pseudouridine(955/2504/2580) synthase RluC
JDDGAC_23205	fldB	-1.2	-3.8	flavodoxin FldB
JDDGAC_02195	uidR	-1.2	-1.7	DNA-binding transcriptional regulator UidR
JDDGAC_20070	pitA	-1.2	-3.0	inorganic phosphate transporter PitA
JDDGAC_21730	nusA	-1.2	-1.9	Transcription termination/antitermination protein NusA
JDDGAC_03200		-1.2	-1.5	hypothetical protein
JDDGAC_04835		-1.2	-0.7	Murein peptide amidase A
JDDGAC_29155	yeeX	-1.1	-1.6	DUF496 domain-containing protein
JDDGAC_05285		-1.1	-2.1	Tyr recombinase domain-containing protein
JDDGAC_26835	nuoH	-1.1	-2.2	NADH-quinone oxidoreductase subunit NuoH
JDDGAC_05720	gp46	-1.1	-1.7	Phage GP46 family protein
JDDGAC_06275	ycgL	-1.1	-1.0	Protein YcgL
JDDGAC_17305	metJ	-1.1	-2.9	met regulon transcriptional regulator MetJ
JDDGAC_08575		-1.1	-1.0	lysozyme
JDDGAC_23660	ygdT	-1.1	-2.3	Protein YgdT
JDDGAC_17185	sthA	-1.1	-4.2	Si-specific NAD(P)(+) transhydrogenase
JDDGAC_08725	ydfA	-1.1	-1.0	Uncharacterized protein YdfA
JDDGAC_08305	torD	-1.1	-3.5	molecular chaperone TorD
JDDGAC_08995	aspC	-1.1	-0.9	aspartate transaminase
JDDGAC_21820	yhbP	-1.1	-1.5	YhbP family protein
JDDGAC_11265	fes	-1.1	-1.9	enterobactin/ferric enterobactin esterase
JDDGAC_19420	yibL	-1.0	-1.3	YibL family ribosome-associated protein
JDDGAC_04955	pspA	-1.0	-1.9	phage shock protein PspA
JDDGAC_00595		-1.0	-0.7	DUF2511 domain-containing protein
JDDGAC_12160	tgt	-1.0	-2.8	tRNA guanosine(34) transglycosylase Tgt
JDDGAC_00350	fliT	-1.0	-1.5	flagella biosynthesis regulatory protein FliT
JDDGAC_00630	azuC	-1.0	-1.7	stress response protein AzuC
JDDGAC_09510		-1.0	-1.8	hypothetical protein
JDDGAC_03775	gadB	-1.0	-0.9	glutamate decarboxylase
JDDGAC_05990	rssB	-1.0	-2.5	two-component system response regulator RssB
JDDGAC_07785	tnpB	-1.0	-1.3	IS66 family insertion sequence element accessory protein TnpB
JDDGAC_21415	argR	-1.0	-2.0	transcriptional regulator ArgR
JDDGAC_02120	rsxE	-1.0	-2.2	electron transport complex subunit RsxE
JDDGAC_08155	pgaB	-1.0	-2.6	poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB
JDDGAC_29030		-1.0	-0.6	Putative prophage portal protein
JDDGAC_11920	glnK	-1.0	-0.7	P-II family nitrogen regulator
JDDGAC_05065	rnb	-1.0	-1.5	exoribonuclease II
JDDGAC_11375		-1.0	-0.8	hypothetical protein
JDDGAC_22870	rdgB	-1.0	-1.6	XTP/dITP diphosphatase
JDDGAC_06565	ybcN	-1.0	-0.7	Uncharacterized protein YbcN
JDDGAC_27680		-1.0	-1.2	Ead/Ea22-like protein
JDDGAC_29110		-1.0	-1.5	host specificity protein J
JDDGAC_01695	ydiV	-1.0	-1.5	anti-FlhDC factor
JDDGAC_05075	yciZ	-1.0	-0.7	UPF0509 protein YciZ
JDDGAC_01870	fumD	-1.0	-0.8	fumarate hydratase FumD
JDDGAC_21670	greA	-1.0	-2.1	transcription elongation factor GreA
JDDGAC_29160	yeeW	-1.0	-1.0	Protein YeeW
JDDGAC_28255	glpR	-1.0	-1.5	transcriptional regulator
JDDGAC_27880		-1.0	-0.9	Phage protein
JDDGAC_03620	sad	-1.0	-2.4	succinate-semialdehyde dehydrogenase
JDDGAC_07140	bhsA	-1.0	-1.3	multiple stress resistance protein BhsA
JDDGAC_04570		-0.9	-1.5	DUF1367 domain-containing protein
JDDGAC_27495	mglA	-0.9	-2.2	galactose/methyl galactoside ABC transporter ATP-binding protein MglA
JDDGAC_07885	ureA	-0.9	-2.2	urease subunit gamma
JDDGAC_08790	yccX	-0.9	-1.6	acylphosphatase
JDDGAC_14880	yjjG	-0.9	-5.0	pyrimidine 5'-nucleotidase
JDDGAC_00840	ruvC	-0.9	-1.4	crossover junction endodeoxyribonuclease RuvC
JDDGAC_23460		-0.9	-0.9	Type III secretion protein EprH
JDDGAC_07040		-0.9	-0.8	replication protein
JDDGAC_01560	chbG	-0.9	-2.6	chitin disaccharide deacetylase
JDDGAC_27165	apbE	-0.9	-3.1	FAD:protein FMN transferase ApbE
JDDGAC_15900	miaA	-0.9	-0.9	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA
JDDGAC_03510	ydfI	-0.9	-2.4	Uncharacterized oxidoreductase YdfI
JDDGAC_06905		-0.9	-0.7	hypothetical protein
JDDGAC_06840		-0.9	-2.8	phage tail protein
JDDGAC_00245	fliQ	-0.9	-1.4	flagellar biosynthesis protein FliQ
JDDGAC_06975	rusA	-0.9	-0.6	Endodeoxyribonuclease RusA
JDDGAC_10690	yafF	-0.9	-0.9	ISAs1 family transposase
JDDGAC_26875	elaD	-0.9	-0.8	ElaD/SseL family deubiquitinase
JDDGAC_10115		-0.9	-2.4	phage tail protein
JDDGAC_26035	eutK	-0.9	-1.8	ethanolamine utilization microcompartment protein EutK
JDDGAC_28780		-0.9	-1.3	antitermination protein N
JDDGAC_04170	ydcA	-0.9	-1.3	Uncharacterized protein YdcA
JDDGAC_03860	yddM	-0.9	-0.7	HigA family addiction module antitoxin
JDDGAC_24320	gutQ	-0.9	-3.6	arabinose-5-phosphate isomerase GutQ
JDDGAC_09920	espX2	-0.9	-0.8	type III secretion system effector EspX2
JDDGAC_07050		-0.9	-0.6	Rha family transcriptional regulator
JDDGAC_09600	ybjN	-0.9	-1.1	Uncharacterized protein YbjN
JDDGAC_11805	recR	-0.9	-1.4	recombination mediator RecR
JDDGAC_25245	hcaC	-0.9	-2.2	bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit
JDDGAC_01735	ydiS	-0.9	-1.6	putative electron transfer flavoprotein-quinone oxidoreductase YdiS
JDDGAC_17550	frvA	-0.9	-2.3	PTS fructose transporter subunit IIA
JDDGAC_05220	trpA	-0.9	-1.4	tryptophan synthase subunit alpha
JDDGAC_05250	nleG	-0.9	-0.9	T3SS effector E3 ubiquitin-protein ligase NleG
JDDGAC_26595	yfcL	-0.9	-2.8	Uncharacterized protein YfcL	conserved

Specific Phenotypes

None in this experiment

For Escherichia coli ECRC98 in phage experiments

For phage Phage across organisms