Experiment set3S215 for Escherichia coli ECRC98

200 most important genes:

gene	name	fitness	t score	description
JDDGAC_26485	Arg_trna	-4.3	-2.9	tRNA-Arg(cct)
JDDGAC_17910	tatA	-4.1	-1.5	Sec-independent protein translocase subunit TatA
JDDGAC_05135		-3.9	-2.4	Protein, C-ter, truncated protein
JDDGAC_01080	mntP	-3.5	-2.1	manganese efflux pump MntP
JDDGAC_10510		-3.3	-1.7	hypothetical protein
JDDGAC_14865	ytjA	-3.3	-1.2	UPF0391 membrane protein YtjA
JDDGAC_14890	holD	-3.3	-1.2	DNA polymerase III subunit psi
JDDGAC_11920	glnK	-3.2	-1.9	P-II family nitrogen regulator
JDDGAC_08445	lomR	-3.1	-1.1	Ail/Lom family protein
JDDGAC_14270	rsmH	-3.1	-1.9	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH
JDDGAC_28445	wcaE	-3.0	-1.8	colanic acid biosynthesis glycosyltransferase WcaE
JDDGAC_28905	Arg_trna	-3.0	-1.1	tRNA-Arg(tcg)
JDDGAC_00595		-2.9	-1.8	DUF2511 domain-containing protein
JDDGAC_07825		-2.9	-1.0	Membrane protein
JDDGAC_03210		-2.9	-1.0	hypothetical protein
JDDGAC_09290	oRF81	-2.9	-1.0	Uncharacterized protein in GpA 5'region
JDDGAC_14420	surA	-2.8	-2.0	peptidylprolyl isomerase SurA
JDDGAC_08145	dgcT	-2.8	-1.7	putative diguanylate cyclase DgcT
JDDGAC_20700	igaA	-2.8	-2.0	intracellular growth attenuator protein IgaA
JDDGAC_02040	ydhF	-2.7	-1.7	Oxidoreductase YdhF
JDDGAC_05580		-2.6	-1.3	hypothetical protein
JDDGAC_03880	yddG	-2.6	-1.8	aromatic amino acid efflux DMT transporter YddG
JDDGAC_06615	nudJ	-2.5	-1.4	phosphatase NudJ
JDDGAC_06125	prfA	-2.5	-1.2	peptide chain release factor 1
JDDGAC_06905		-2.5	-1.5	hypothetical protein
JDDGAC_06650		-2.4	-1.7	terminase
JDDGAC_05565		-2.4	-2.3	hypothetical protein
JDDGAC_02145	rsxA	-2.4	-1.2	electron transport complex subunit RsxA
JDDGAC_25525		-2.4	-1.1	hypothetical protein
JDDGAC_15900	miaA	-2.3	-1.6	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA
JDDGAC_28830		-2.3	-3.2	Endonuclease
JDDGAC_29920		-2.3	-2.4	hypothetical protein
JDDGAC_25065	lepA	-2.3	-1.6	translation elongation factor 4
JDDGAC_17425	yiiR	-2.3	-1.6	Uncharacterized protein YiiR
JDDGAC_07785	tnpB	-2.2	-1.4	IS66 family insertion sequence element accessory protein TnpB
JDDGAC_27065	yfaE	-2.2	-1.1	ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE
JDDGAC_02470		-2.1	-1.6	DNA-binding protein
JDDGAC_28800		-2.1	-1.1	XRE family transcriptional regulator
JDDGAC_23565		-2.1	-1.1	hypothetical protein
JDDGAC_00880	znuA	-2.1	-2.5	zinc ABC transporter substrate-binding protein ZnuA
JDDGAC_00145	hiuH	-2.1	-0.7	hydroxyisourate hydrolase
JDDGAC_22870	rdgB	-2.1	-2.7	XTP/dITP diphosphatase
JDDGAC_05550		-2.0	-1.4	Uncharacterized protein gp11
JDDGAC_13050		-2.0	-1.0	phage tail protein
JDDGAC_06700		-2.0	-1.4	DUF4222 domain-containing protein
JDDGAC_30055	yubL	-2.0	-1.8	UPF0401 protein YubL
JDDGAC_03860	yddM	-2.0	-1.4	HigA family addiction module antitoxin
JDDGAC_03650	lsrG	-2.0	-1.4	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase
JDDGAC_00770	cutC	-2.0	-1.3	copper homeostasis protein CutC
JDDGAC_02120	rsxE	-1.9	-3.2	electron transport complex subunit RsxE
JDDGAC_11975		-1.9	-1.3	Lon protease
JDDGAC_08560	nu1	-1.9	-2.0	Prophage Qin DNA packaging protein NU1-like protein
JDDGAC_10225		-1.8	-0.9	DUF3927 domain-containing protein
JDDGAC_21670	greA	-1.8	-2.2	transcription elongation factor GreA
JDDGAC_04565		-1.8	-1.1	DUF1364 domain-containing protein
JDDGAC_17455	pfkA	-1.8	-3.2	6-phosphofructokinase
JDDGAC_14440	apaH	-1.8	-1.2	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH
JDDGAC_06180		-1.7	-1.6	PTS-dependent dihydroxyacetone kinase
JDDGAC_18070	cyaA	-1.7	-1.4	class I adenylate cyclase
JDDGAC_25435	guaB	-1.7	-4.7	IMP dehydrogenase
JDDGAC_00120		-1.7	-1.0	tRNA-Xxx
JDDGAC_04130	ydcH	-1.7	-0.9	Uncharacterized protein YdcH
JDDGAC_07140	bhsA	-1.7	-1.6	multiple stress resistance protein BhsA
JDDGAC_03730	ydeQ	-1.7	-0.9	Uncharacterized fimbrial-like protein YdeQ
JDDGAC_02220		-1.7	-0.9	Putative outer membrane porin protein
JDDGAC_17715	typA	-1.7	-7.4	ribosome-dependent GTPase TypA
JDDGAC_06565	ybcN	-1.6	-0.8	Uncharacterized protein YbcN
JDDGAC_11580	allA	-1.6	-1.6	ureidoglycolate lyase
JDDGAC_04940	pspD	-1.6	-0.8	phage shock protein PspD
JDDGAC_29320	rfaF	-1.6	-2.9	Glycosyltransferase family 9 (heptosyltransferase)
JDDGAC_24995	trxC	-1.6	-1.7	thioredoxin TrxC
JDDGAC_19215	rph	-1.6	-5.7	ribonuclease PH
JDDGAC_29015		-1.6	-1.4	phage major capsid protein
JDDGAC_04295	ydbJ	-1.6	-1.1	Uncharacterized protein YdbJ
JDDGAC_09900	ybiE	-1.6	-2.1	Protein YbiE
JDDGAC_07045	eCs1768	-1.6	-2.1	phage replisome organizer
JDDGAC_11235	fepD	-1.6	-1.6	ferrienterobactin ABC transporter permease
JDDGAC_20510	yhgO	-1.6	-1.5	Protein YhgO
JDDGAC_15620	chpB	-1.6	-2.0	type II toxin-antitoxin system ChpB family toxin
JDDGAC_07225	fabF	-1.5	-2.7	beta-ketoacyl-ACP synthase II
JDDGAC_10700	rhsA	-1.5	-1.7	RHS element protein
JDDGAC_13035		-1.5	-1.1	tRNA-Xxx
JDDGAC_06620	mnmA	-1.5	-1.2	tRNA 2-thiouridine(34) synthase MnmA
JDDGAC_02200	lacZ	-1.5	-1.3	Beta-galactosidase/beta-glucuronidase
JDDGAC_29165		-1.5	-0.7	toxin of the YeeV-YeeU toxin-antitoxin system
JDDGAC_13240	ymfM	-1.5	-1.3	Uncharacterized protein YmfM
JDDGAC_23070	meaB	-1.5	-1.7	methylmalonyl Co-A mutase-associated GTPase MeaB
JDDGAC_13175	rzpD	-1.5	-0.9	prophage endopeptidase RzpD
JDDGAC_28890		-1.5	-1.3	Serine/threonine-protein phosphatase
JDDGAC_01515	cho	-1.5	-2.1	excinuclease Cho
JDDGAC_25045	rseA	-1.5	-2.7	anti-sigma-E factor RseA
JDDGAC_29355		-1.4	-1.8	DUF4224 domain-containing protein
JDDGAC_17390	zapB	-1.4	-1.6	septal ring assembly protein ZapB
JDDGAC_02170	add	-1.4	-1.2	adenosine deaminase
JDDGAC_00285	fliI	-1.4	-1.6	flagellum-specific ATP synthase FliI
JDDGAC_21780	deaD	-1.4	-2.8	ATP-dependent RNA helicase DeaD
JDDGAC_06075	chaB	-1.4	-1.2	putative cation transport regulator ChaB
JDDGAC_13545		-1.4	-2.0	hypothetical protein
JDDGAC_04850	tyrR	-1.4	-1.0	transcriptional regulator TyrR
JDDGAC_21585	kdsC	-1.3	-1.1	3-deoxy-manno-octulosonate-8-phosphatase KdsC
JDDGAC_02375	ynfC	-1.3	-1.2	YnfC family lipoprotein
JDDGAC_00935	yebF	-1.3	-0.9	Protein YebF
JDDGAC_03505	ydfJ	-1.3	-1.3	Putative transporter YdfJ
JDDGAC_28060	zorO	-1.3	-0.8	Small toxic protein ZorO
JDDGAC_00225	yodD	-1.3	-2.1	YodD family peroxide/acid resistance protein
JDDGAC_26910	menB	-1.3	-2.1	1,4-dihydroxy-2-naphthoyl-CoA synthase
JDDGAC_10355	acrZ	-1.3	-0.8	multidrug efflux pump accessory protein AcrZ
JDDGAC_05530		-1.3	-1.1	hypothetical protein
JDDGAC_24450	emrR	-1.3	-1.2	multidrug efflux transporter EmrAB transcriptional repressor EmrR
JDDGAC_26240	yfeD	-1.3	-3.4	Uncharacterized protein YfeD
JDDGAC_04725	ynaL	-1.3	-0.8	Protein YnaL
JDDGAC_29975	sopA	-1.3	-1.2	plasmid-partitioning protein SopA
JDDGAC_06425		-1.3	-1.0	phage minor tail protein L
JDDGAC_01440	ynjD	-1.3	-0.7	Uncharacterized ABC transporter ATP-binding protein YnjD
JDDGAC_05070	pdeR	-1.3	-1.9	cyclic di-GMP phosphodiesterase
JDDGAC_13425		-1.3	-1.1	dCTP deaminase
JDDGAC_09030	cmoM	-1.2	-2.2	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM
JDDGAC_08755		-1.2	-2.8	DUF1482 domain-containing protein
JDDGAC_19355	envC	-1.2	-4.8	murein hydrolase activator EnvC
JDDGAC_10735	speFL	-1.2	-1.7	Leader peptide SpeFL
JDDGAC_19070	escG	-1.2	-1.0	type III secretion system LEE needle protein cochaperone EscG
JDDGAC_05535		-1.2	-0.6	hypothetical protein
JDDGAC_07275	rluC	-1.2	-2.0	23S rRNA pseudouridine(955/2504/2580) synthase RluC
JDDGAC_10465	tolA	-1.2	-1.1	cell envelope integrity protein TolA
JDDGAC_01960	cfa	-1.2	-1.3	cyclopropane fatty acyl phospholipid synthase
JDDGAC_09000	gloC	-1.2	-1.4	hydroxyacylglutathione hydrolase GloC
JDDGAC_26270	ypeD	-1.2	-1.8	Protein YpeD
JDDGAC_14625	nhaA	-1.2	-4.9	Na+/H+ antiporter NhaA
JDDGAC_03830	ddpF	-1.2	-2.4	putative D,D-dipeptide transport ATP-binding protein DdpF
JDDGAC_17730	glnL	-1.2	-1.7	nitrogen regulation protein NR(II)
JDDGAC_05710		-1.2	-1.2	phage tail protein
JDDGAC_23460		-1.2	-0.9	Type III secretion protein EprH
JDDGAC_04090	rlhA	-1.2	-1.9	23S rRNA 5-hydroxycytidine C2501 synthase
JDDGAC_23205	fldB	-1.2	-3.1	flavodoxin FldB
JDDGAC_00570		-1.2	-1.5	hypothetical protein
JDDGAC_10205		-1.2	-0.8	Putative bacteriophage protein (Gene 65)
JDDGAC_05655		-1.2	-3.1	protease
JDDGAC_21580	lptC	-1.1	-1.8	LPS export ABC transporter periplasmic protein LptC
JDDGAC_02115	nth	-1.1	-2.7	endonuclease III
JDDGAC_12325	iprA	-1.1	-2.2	hydrogen peroxide resistance inhibitor IprA
JDDGAC_00910	zwf	-1.1	-1.0	glucose-6-phosphate dehydrogenase
JDDGAC_07485	csgC	-1.1	-0.9	curli assembly protein CsgC
JDDGAC_06290	ycgJ	-1.1	-1.4	Uncharacterized protein YcgJ
JDDGAC_03900	espR1	-1.1	-1.1	T3SS effector leucine-rich repeat protein EspR1
JDDGAC_04890	ycjS	-1.1	-2.6	D-glucoside 3-dehydrogenase
JDDGAC_03625	glsB	-1.1	-1.5	glutaminase B
JDDGAC_24735	rrrD	-1.1	-0.7	lysozyme
JDDGAC_11130	rnk	-1.1	-1.6	nucleoside diphosphate kinase regulator
JDDGAC_27270	dsbE	-1.1	-1.1	thiol:disulfide interchange protein DsbE
JDDGAC_07330	flgC	-1.1	-1.5	flagellar basal body rod protein FlgC
JDDGAC_22510	qseC	-1.1	-3.8	two-component system sensor histidine kinase QseC
JDDGAC_28850		-1.1	-1.3	restriction alleviation protein, Lar family
JDDGAC_16125	ghoT	-1.1	-1.5	type V toxin-antitoxin system toxin GhoT
JDDGAC_25690		-1.1	-1.1	acyltransferase
JDDGAC_27000	yfaU	-1.1	-2.1	2-keto-3-deoxy-L-rhamnonate aldolase
JDDGAC_28885	ninG	-1.1	-1.1	Protein ninG
JDDGAC_14075	acnB	-1.1	-1.0	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
JDDGAC_01450	ynjB	-1.1	-1.3	ABC transporter substrate-binding protein
JDDGAC_25315	hscA	-1.1	-0.7	Fe-S protein assembly chaperone HscA
JDDGAC_04575		-1.1	-0.8	Bacteriophage cohesive ends
JDDGAC_09680	gstB	-1.1	-2.1	glutathione S-transferase GstB
JDDGAC_29120		-1.1	-1.2	phage tail protein
JDDGAC_02065	slyA	-1.1	-1.4	transcriptional regulator SlyA
JDDGAC_03775	gadB	-1.1	-1.2	glutamate decarboxylase
JDDGAC_10045	ybhB	-1.1	-1.8	kinase inhibitor
JDDGAC_08730	ydfB	-1.1	-0.9	Uncharacterized protein YdfB
JDDGAC_04485		-1.1	-0.5	Holin
JDDGAC_06755		-1.1	-0.7	hypothetical protein
JDDGAC_00890	lpxM	-1.1	-1.4	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase
JDDGAC_27740		-1.1	-0.7	regulator
JDDGAC_05875		-1.1	-2.0	integrase
JDDGAC_13150		-1.0	-2.7	phage portal protein
JDDGAC_10115		-1.0	-2.0	phage tail protein
JDDGAC_04805	mppA	-1.0	-2.5	murein tripeptide ABC transporter substrate-binding protein MppA
JDDGAC_01585	ybcI	-1.0	-0.8	metal-dependent hydrolase
JDDGAC_25985	eutN	-1.0	-2.4	ethanolamine utilization microcompartment protein EutN
JDDGAC_19455		-1.0	-1.1	Immunity protein 57
JDDGAC_05285		-1.0	-1.5	Tyr recombinase domain-containing protein
JDDGAC_04005	yncE	-1.0	-3.0	Uncharacterized protein YncE
JDDGAC_07435	mdtG	-1.0	-2.2	multidrug efflux MFS transporter MdtG
JDDGAC_15190	fimC	-1.0	-1.8	type 1 fimbria chaperone FimC
JDDGAC_05585		-1.0	-1.0	hypothetical protein
JDDGAC_14285	fruL	-1.0	-1.0	Putative fruR/shl operon leader peptide
JDDGAC_06825		-1.0	-0.5	phage tail tape measure protein
JDDGAC_24805	bamE	-1.0	-1.6	outer membrane protein assembly factor BamE
JDDGAC_18085	hemX	-1.0	-4.2	uroporphyrinogen-III C-methyltransferase
JDDGAC_15075	yjiL	-1.0	-1.6	Uncharacterized protein YjiL
JDDGAC_23550	yqeL	-1.0	-1.1	Uncharacterized protein YqeL
JDDGAC_02475	dnaC	-1.0	-0.8	DNA replication protein DnaC
JDDGAC_11390	tnp-ISAs1	-1.0	-1.1	ISAs1 family transposase
JDDGAC_10910	gltK	-1.0	-3.2	glutamate/aspartate ABC transporter permease GltK
JDDGAC_15180	fimF	-1.0	-2.5	type 1 fimbria minor subunit FimF
JDDGAC_23140	ygfB	-1.0	-1.1	UPF0149 family protein YgfB
JDDGAC_07025		-1.0	-0.9	DUF4406 domain-containing protein
JDDGAC_14430	rsmA	-1.0	-1.2	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA
JDDGAC_24260	hycF	-1.0	-1.3	formate hydrogenlyase subunit HycF
JDDGAC_05695	gp41	-1.0	-1.9	Phage tail assembly chaperone proteins, E, or 41 or 14
JDDGAC_00755	yecT	-1.0	-1.2	Uncharacterized protein YecT
JDDGAC_11310	ybdF	-1.0	-2.4	MmcQ/YjbR family DNA-binding protein
JDDGAC_23065		-1.0	-1.3	Putative acetyl-CoA hydrolase/transferase

Specific Phenotypes

For 2 genes in this experiment

For phage Phage in Escherichia coli ECRC98

For phage Phage across organisms