Experiment set3IT093 for Pseudomonas fluorescens GW456-L13

Compare to:

Cytosine nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_362 -6.6 -4.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_2046 -5.9 -4.1 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_1472 -5.8 -5.7 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_3947 -5.8 -4.0 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_1368 -5.8 -4.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_5001 -5.8 -8.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_3940 -5.8 -7.9 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_2842 -5.7 -5.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1540 -5.5 -10.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_3934 -5.5 -12.8 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_565 -5.5 -3.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_1010 -5.4 -8.3 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_1222 -5.4 -6.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_272 -5.3 -28.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_172 -5.1 -9.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1007 -5.1 -11.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_3945 -5.1 -12.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_1221 -5.0 -14.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_5000 -4.9 -16.2 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_359 -4.9 -10.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_271 -4.9 -18.8 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_149 -4.9 -8.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_347 -4.8 -9.8 Nitrogen regulation protein NR(I) compare
PfGW456L13_3948 -4.8 -8.6 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_4009 -4.8 -14.9 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_951 -4.7 -14.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_1739 -4.7 -11.3 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_1217 -4.7 -20.1 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_854 -4.6 -3.2 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_358 -4.6 -4.5 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_845 -4.6 -7.0 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_3253 -4.6 -18.6 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
PfGW456L13_361 -4.6 -13.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_1050 -4.3 -10.9 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_2843 -4.3 -11.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_1615 -4.3 -2.9 Probable transmembrane protein compare
PfGW456L13_1749 -4.3 -5.1 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_913 -4.3 -9.1 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_2230 -4.2 -11.8 Cys regulon transcriptional activator CysB compare
PfGW456L13_1538 -4.2 -13.0 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_1233 -4.1 -5.6 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_302 -4.0 -6.2 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_2032 -3.9 -7.0 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_4671 -3.9 -13.9 Transcriptional regulator, Cro/CI family compare
PfGW456L13_1220 -3.9 -6.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_2656 -3.8 -8.4 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_892 -3.8 -13.5 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
PfGW456L13_1539 -3.7 -10.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_4711 -3.7 -21.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_1006 -3.7 -5.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_1972 -3.6 -3.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_275 -3.6 -2.5 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_2103 -3.5 -5.8 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_566 -3.4 -8.8 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_303 -3.3 -3.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_4854 -3.2 -9.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_943 -3.2 -6.2 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
PfGW456L13_727 -3.1 -10.8 LysR family transcriptional regulator PA5437 compare
PfGW456L13_346 -3.1 -3.8 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
PfGW456L13_793 -3.1 -4.1 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_276 -3.0 -2.7 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_1889 -2.9 -4.3 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_4165 -2.9 -4.1 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_4859 -2.9 -5.0 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_2552 -2.8 -8.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_5008 -2.8 -2.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
PfGW456L13_644 -2.8 -10.4 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_3894 -2.7 -3.0 Integration host factor alpha subunit compare
PfGW456L13_50 -2.7 -9.6 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_2176 -2.7 -9.3 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_728 -2.6 -13.8 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
PfGW456L13_4125 -2.6 -3.4 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_729 -2.6 -9.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
PfGW456L13_2445 -2.5 -7.2 Cytosine deaminase (EC 3.5.4.1) conserved
PfGW456L13_4253 -2.3 -4.6 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1644 -2.3 -5.9 Cell division protein MraZ compare
PfGW456L13_5006 -2.2 -2.5 Uncharacterized ABC transporter, periplasmic component YrbD compare
PfGW456L13_1524 -2.1 -6.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_1735 -2.1 -4.1 Glycerol uptake facilitator protein compare
PfGW456L13_1984 -1.9 -3.3 Mg/Co/Ni transporter MgtE / CBS domain compare
PfGW456L13_1865 -1.9 -2.1 Cold shock protein CspA compare
PfGW456L13_949 -1.9 -10.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_360 -1.9 -2.5 FIG00956267: hypothetical protein compare
PfGW456L13_1498 -1.9 -1.7 FIG060329: MOSC domain protein compare
PfGW456L13_3503 -1.7 -7.0 Beta-ureidopropionase (EC 3.5.1.6) (from data) compare
PfGW456L13_427 -1.6 -2.1 Two-component system response regulator OmpR compare
PfGW456L13_5150 -1.6 -2.8 Exodeoxyribonuclease V alpha chain (EC 3.1.11.5) compare
PfGW456L13_973 -1.6 -8.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_1853 -1.6 -3.6 Holliday junction DNA helicase RuvB compare
PfGW456L13_2035 -1.5 -7.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
PfGW456L13_4012 -1.5 -2.4 VacJ-like lipoprotein precursor compare
PfGW456L13_5003 -1.5 -2.5 YrbA protein compare
PfGW456L13_1147 -1.5 -9.6 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_5067 -1.5 -8.9 Ornithine decarboxylase (EC 4.1.1.17) / Arginine decarboxylase (EC 4.1.1.19) compare
PfGW456L13_953 -1.5 -9.3 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_1901 -1.5 -5.8 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_2237 -1.4 -2.4 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_2162 -1.4 -7.0 Cell division protein BolA compare
PfGW456L13_3960 -1.4 -7.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
PfGW456L13_5089 -1.4 -1.9 Transcription termination protein NusA compare
PfGW456L13_367 -1.4 -3.0 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
PfGW456L13_1284 -1.4 -2.5 Putative transport protein compare
PfGW456L13_2623 -1.4 -2.4 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_838 -1.4 -8.3 Ammonium transporter compare
PfGW456L13_5005 -1.4 -3.6 Uncharacterized ABC transporter, auxiliary component YrbC compare
PfGW456L13_3506 -1.3 -5.8 Dihydropyrimidinase (EC 3.5.2.2) (from data) conserved
PfGW456L13_2084 -1.3 -2.3 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_2651 -1.3 -4.7 Cell division protein FtsK compare
PfGW456L13_4898 -1.3 -1.7 Inner membrane protein compare
PfGW456L13_812 -1.3 -2.8 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
PfGW456L13_779 -1.2 -7.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
PfGW456L13_4842 -1.2 -2.6 Translation elongation factor LepA compare
PfGW456L13_4662 -1.2 -1.4 Transcriptional regulator, LuxR family compare
PfGW456L13_4545 -1.2 -2.5 Integral membrane protein compare
PfGW456L13_2107 -1.2 -3.5 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179) compare
PfGW456L13_4231 -1.2 -2.5 hypothetical protein compare
PfGW456L13_3512 -1.2 -3.2 Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) compare
PfGW456L13_673 -1.1 -7.4 Chromosome (plasmid) partitioning protein ParA compare
PfGW456L13_1975 -1.1 -2.4 Succinylarginine dihydrolase (EC 3.5.3.23) compare
PfGW456L13_1824 -1.1 -2.0 transcriptional regulator MvaT, P16 subunit compare
PfGW456L13_1936 -1.1 -2.3 RNA polymerase sigma-70 factor, ECF subfamily compare
PfGW456L13_4207 -1.1 -4.7 Periplasmic protease compare
PfGW456L13_3505 -1.1 -6.0 uridine/cytosine permease (from data) conserved
PfGW456L13_1574 -1.1 -3.0 GTP-binding and nucleic acid-binding protein YchF compare
PfGW456L13_2483 -1.1 -7.0 Permease of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_430 -1.1 -5.5 Glutamate--cysteine ligase (EC 6.3.2.2) compare
PfGW456L13_4610 -1.1 -2.3 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
PfGW456L13_3795 -1.1 -5.2 sensor histidine kinase compare
PfGW456L13_1655 -1.0 -1.9 D-alanine--D-alanine ligase (EC 6.3.2.4) compare
PfGW456L13_2854 -1.0 -4.0 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
PfGW456L13_3302 -1.0 -1.7 FIG00954674: hypothetical protein compare
PfGW456L13_2631 -1.0 -2.4 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_1662 -1.0 -5.5 Heavy metal sensor histidine kinase compare
PfGW456L13_5152 -1.0 -3.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
PfGW456L13_4992 -1.0 -7.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_1838 -1.0 -3.4 Sensory box histidine kinase compare
PfGW456L13_1927 -1.0 -5.5 Gluconate permease compare
PfGW456L13_787 -1.0 -5.3 Exodeoxyribonuclease III (EC 3.1.11.2) compare
PfGW456L13_3508 -1.0 -6.2 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) compare
PfGW456L13_3 -1.0 -7.2 Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18) compare
PfGW456L13_1842 -1.0 -6.3 Outer membrane porin, OprD family compare
PfGW456L13_1690 -1.0 -2.4 Molybdenum cofactor biosynthesis protein MoaD compare
PfGW456L13_1009 -1.0 -1.7 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
PfGW456L13_2632 -0.9 -1.8 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_5086 -0.9 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
PfGW456L13_4088 -0.9 -1.9 Transcriptional regulator, GntR family compare
PfGW456L13_150 -0.9 -0.8 hypothetical protein compare
PfGW456L13_2189 -0.9 -3.9 UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid transferase compare
PfGW456L13_2773 -0.9 -2.2 Phage protein compare
PfGW456L13_274 -0.9 -6.0 DamX, an inner membrane protein involved in bile resistance compare
PfGW456L13_1852 -0.9 -3.9 Holliday junction DNA helicase RuvA compare
PfGW456L13_5018 -0.9 -5.1 Phosphocarrier protein, nitrogen regulation associated compare
PfGW456L13_2553 -0.9 -5.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_3507 -0.9 -3.7 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism compare
PfGW456L13_2484 -0.9 -3.6 Transcriptional regulators, LysR family compare
PfGW456L13_1011 -0.9 -1.8 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_582 -0.8 -1.9 probable exported protein YPO0432 compare
PfGW456L13_848 -0.8 -1.7 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
PfGW456L13_3311 -0.8 -1.8 hypothetical protein compare
PfGW456L13_2592 -0.8 -1.6 hypothetical protein compare
PfGW456L13_1973 -0.8 -2.6 Arginine N-succinyltransferase (EC 2.3.1.109) compare
PfGW456L13_3891 -0.8 -2.4 hypothetical protein compare
PfGW456L13_1603 -0.8 -1.6 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_2551 -0.8 -1.9 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_4097 -0.8 -4.0 Nitrate ABC transporter, nitrate-binding protein compare
PfGW456L13_134 -0.8 -5.8 Protein containing transglutaminase-like domain, putative cysteine protease compare
PfGW456L13_5060 -0.8 -2.8 Peptide chain release factor 3 compare
PfGW456L13_1219 -0.8 -2.0 hypothetical protein compare
PfGW456L13_2034 -0.8 -1.6 hypothetical protein compare
PfGW456L13_4993 -0.8 -5.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_4 -0.8 -5.8 LysR family transcriptional regulator PA0133 compare
PfGW456L13_2554 -0.8 -4.3 ATP-dependent protease La (EC 3.4.21.53) Type I compare
PfGW456L13_4107 -0.8 -3.9 CmpX compare
PfGW456L13_2645 -0.8 -3.2 ATP-dependent Clp protease adaptor protein ClpS compare
PfGW456L13_2436 -0.8 -3.1 Phenylacetic acid degradation operon negative regulatory protein PaaX compare
PfGW456L13_1479 -0.8 -0.9 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
PfGW456L13_4242 -0.8 -4.9 Cobyrinic acid A,C-diamide synthase compare
PfGW456L13_111 -0.7 -1.6 Urease accessory protein UreE compare
PfGW456L13_2271 -0.7 -0.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_1553 -0.7 -4.4 Carbonic anhydrase (EC 4.2.1.1) compare
PfGW456L13_3051 -0.7 -2.8 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
PfGW456L13_3427 -0.7 -1.4 Enoyl-CoA hydratase (EC 4.2.1.17) compare
PfGW456L13_2957 -0.7 -3.0 Sensory histidine kinase QseC compare
PfGW456L13_1363 -0.7 -2.3 Rare lipoprotein A precursor compare
PfGW456L13_621 -0.7 -2.2 hypothetical protein compare
PfGW456L13_1020 -0.7 -3.2 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_1997 -0.7 -3.1 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_874 -0.7 -6.0 Polyphosphate kinase (EC 2.7.4.1) compare
PfGW456L13_844 -0.7 -1.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
PfGW456L13_4036 -0.7 -1.6 FIG00954079: hypothetical protein compare
PfGW456L13_3442 -0.7 -2.1 hypothetical protein compare
PfGW456L13_4238 -0.7 -2.6 Cobyric acid synthase (EC 6.3.5.10) compare
PfGW456L13_2952 -0.7 -1.8 2-ketogluconate utilization repressor PtxS compare
PfGW456L13_1062 -0.7 -4.4 Transcriptional regulator, ArsR family / Methyltransferase fusion compare
PfGW456L13_135 -0.7 -5.1 Protein containing domains DUF404, DUF407, DUF403 compare
PfGW456L13_4507 -0.7 -2.0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_1625 -0.7 -1.4 FIG00958649: hypothetical protein compare
PfGW456L13_2186 -0.7 -2.5 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) compare
PfGW456L13_674 -0.7 -3.5 Chromosome (plasmid) partitioning protein ParB compare
PfGW456L13_4511 -0.7 -1.0 Rhodanese-like domain protein compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source Cytosine in Pseudomonas fluorescens GW456-L13

For nitrogen source Cytosine across organisms