Experiment set3IT087 for Pseudomonas fluorescens GW456-L13

Compare to:

Gly-DL-Asp nitrogen source

200 most important genes:

  gene name fitness t score description  
PfGW456L13_1221 -4.0 -9.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
PfGW456L13_149 -4.0 -2.7 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
PfGW456L13_361 -3.9 -5.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
PfGW456L13_358 -3.9 -2.7 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
PfGW456L13_3934 -3.8 -6.3 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
PfGW456L13_2842 -3.8 -2.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
PfGW456L13_1472 -3.8 -2.6 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
PfGW456L13_1217 -3.5 -12.3 Anthranilate synthase, aminase component (EC 4.1.3.27) compare
PfGW456L13_3948 -3.5 -3.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
PfGW456L13_1007 -3.5 -4.8 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_644 -3.5 -4.7 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
PfGW456L13_1222 -3.5 -3.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
PfGW456L13_5000 -3.5 -8.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
PfGW456L13_1010 -3.5 -4.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) compare
PfGW456L13_362 -3.4 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
PfGW456L13_4009 -3.4 -5.7 Transaldolase (EC 2.2.1.2) compare
PfGW456L13_3940 -3.4 -4.7 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
PfGW456L13_1220 -3.4 -6.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_3947 -3.4 -2.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
PfGW456L13_3945 -3.3 -4.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
PfGW456L13_1368 -3.3 -2.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
PfGW456L13_1540 -3.3 -5.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
PfGW456L13_347 -3.3 -5.5 Nitrogen regulation protein NR(I) compare
PfGW456L13_5001 -3.2 -5.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PfGW456L13_359 -3.2 -5.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PfGW456L13_69 -3.2 -1.5 Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) compare
PfGW456L13_1050 -3.1 -3.0 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
PfGW456L13_2920 -3.1 -2.0 FIG00962345: hypothetical protein compare
PfGW456L13_2843 -3.0 -4.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
PfGW456L13_302 -3.0 -3.6 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
PfGW456L13_1006 -3.0 -5.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
PfGW456L13_2981 -2.9 -1.9 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) compare
PfGW456L13_2230 -2.8 -5.9 Cys regulon transcriptional activator CysB compare
PfGW456L13_272 -2.8 -17.4 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_913 -2.8 -2.7 N-acetylglutamate synthase (EC 2.3.1.1) compare
PfGW456L13_5058 -2.8 -7.5 Dipeptide transport ATP-binding protein DppF (TC 3.A.1.5.2) conserved
PfGW456L13_4854 -2.8 -10.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
PfGW456L13_4671 -2.7 -8.0 Transcriptional regulator, Cro/CI family compare
PfGW456L13_1539 -2.7 -6.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
PfGW456L13_2046 -2.7 -3.2 Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94) compare
PfGW456L13_1901 -2.7 -4.5 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
PfGW456L13_4711 -2.7 -11.6 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
PfGW456L13_5056 -2.7 -5.1 Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) conserved
PfGW456L13_973 -2.6 -7.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
PfGW456L13_2032 -2.6 -1.8 Cysteine synthase B (EC 2.5.1.47) compare
PfGW456L13_1521 -2.6 -2.5 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
PfGW456L13_1233 -2.5 -1.7 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) compare
PfGW456L13_1890 -2.5 -5.1 Glucokinase (EC 2.7.1.2) compare
PfGW456L13_1739 -2.5 -5.1 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
PfGW456L13_2176 -2.5 -6.0 Chorismate mutase I (EC 5.4.99.5) / Prephenate dehydratase (EC 4.2.1.51) compare
PfGW456L13_50 -2.5 -4.5 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
PfGW456L13_2773 -2.5 -2.4 Phage protein compare
PfGW456L13_2103 -2.5 -4.4 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_1538 -2.4 -4.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
PfGW456L13_565 -2.4 -3.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
PfGW456L13_2656 -2.4 -4.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
PfGW456L13_1749 -2.3 -1.6 Argininosuccinate synthase (EC 6.3.4.5) compare
PfGW456L13_5057 -2.3 -5.0 Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2) compare
PfGW456L13_5089 -2.3 -1.5 Transcription termination protein NusA compare
PfGW456L13_845 -2.3 -3.1 Diaminopimelate decarboxylase (EC 4.1.1.20) compare
PfGW456L13_276 -2.3 -1.5 Shikimate kinase I (EC 2.7.1.71) compare
PfGW456L13_3253 -2.3 -9.9 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
PfGW456L13_5051 -2.3 -9.2 Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2) conserved
PfGW456L13_951 -2.3 -7.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
PfGW456L13_872 -2.2 -6.2 FIG139438: lipoprotein B compare
PfGW456L13_2484 -2.2 -4.1 Transcriptional regulators, LysR family compare
PfGW456L13_3629 -2.2 -1.9 Lactoylglutathione lyase and related lyases compare
PfGW456L13_271 -2.1 -10.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
PfGW456L13_2483 -2.1 -6.7 Permease of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_949 -2.1 -7.8 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
PfGW456L13_1524 -2.1 -3.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
PfGW456L13_4165 -2.1 -2.0 Chorismate synthase (EC 4.2.3.5) compare
PfGW456L13_346 -2.1 -3.9 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
PfGW456L13_5055 -2.1 -7.0 Dipeptide transport system permease protein DppB (TC 3.A.1.5.2) conserved
PfGW456L13_2623 -1.9 -1.3 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) compare
PfGW456L13_3000 -1.9 -1.7 FIG00961385: hypothetical protein compare
PfGW456L13_1997 -1.9 -3.4 Negative regulator of flagellin synthesis FlgM compare
PfGW456L13_1615 -1.9 -1.5 Probable transmembrane protein compare
PfGW456L13_793 -1.9 -1.3 Acetylglutamate kinase (EC 2.7.2.8) compare
PfGW456L13_953 -1.8 -8.0 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
PfGW456L13_4507 -1.8 -2.5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
PfGW456L13_769 -1.8 -1.2 DNA-binding protein HU-alpha compare
PfGW456L13_303 -1.8 -2.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_3795 -1.8 -6.1 sensor histidine kinase compare
PfGW456L13_1198 -1.8 -3.2 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
PfGW456L13_1603 -1.8 -1.2 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
PfGW456L13_4999 -1.8 -6.4 Histidinol-phosphate aminotransferase (EC 2.6.1.9) compare
PfGW456L13_4026 -1.7 -1.7 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
PfGW456L13_854 -1.7 -1.7 Argininosuccinate lyase (EC 4.3.2.1) compare
PfGW456L13_329 -1.7 -2.9 Histidine utilization repressor compare
PfGW456L13_4125 -1.6 -1.1 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_2592 -1.6 -1.6 hypothetical protein compare
PfGW456L13_4108 -1.6 -2.3 CrfX protein compare
PfGW456L13_757 -1.6 -1.5 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_367 -1.5 -2.1 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
PfGW456L13_4218 -1.5 -2.0 Quaternary ammonium compound-resistance protein SugE compare
PfGW456L13_726 -1.5 -4.4 Phosphogluconate repressor HexR, RpiR family compare
PfGW456L13_566 -1.5 -3.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
PfGW456L13_892 -1.5 -6.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
PfGW456L13_1868 -1.5 -9.8 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) compare
PfGW456L13_705 -1.5 -0.9 FIG00953800: hypothetical protein compare
PfGW456L13_2050 -1.5 -2.4 FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein compare
PfGW456L13_2552 -1.4 -3.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
PfGW456L13_1996 -1.4 -1.6 Flagellar biosynthesis protein FlgN compare
PfGW456L13_1020 -1.4 -3.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
PfGW456L13_2084 -1.4 -1.6 MotA/TolQ/ExbB proton channel family protein compare
PfGW456L13_4207 -1.4 -2.9 Periplasmic protease compare
PfGW456L13_1625 -1.4 -1.4 FIG00958649: hypothetical protein compare
PfGW456L13_848 -1.4 -1.8 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
PfGW456L13_4639 -1.3 -2.0 Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) compare
PfGW456L13_994 -1.3 -2.0 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
PfGW456L13_1972 -1.3 -1.3 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
PfGW456L13_952 -1.3 -2.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
PfGW456L13_3862 -1.3 -1.9 DoxX family protein compare
PfGW456L13_62 -1.3 -1.0 hypothetical protein compare
PfGW456L13_2952 -1.3 -2.0 2-ketogluconate utilization repressor PtxS compare
PfGW456L13_5121 -1.3 -1.0 hypothetical protein compare
PfGW456L13_4088 -1.3 -1.5 Transcriptional regulator, GntR family compare
PfGW456L13_4859 -1.3 -1.2 Outer membrane protein YfgL, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and NlpB) compare
PfGW456L13_4253 -1.3 -1.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
PfGW456L13_1205 -1.3 -3.9 Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) compare
PfGW456L13_2553 -1.2 -4.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
PfGW456L13_2632 -1.2 -1.9 NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) compare
PfGW456L13_880 -1.2 -2.9 Transcriptional regulator, GntR family compare
PfGW456L13_1147 -1.2 -6.3 Biotin synthase (EC 2.8.1.6) compare
PfGW456L13_5018 -1.2 -4.0 Phosphocarrier protein, nitrogen regulation associated compare
PfGW456L13_1644 -1.2 -2.5 Cell division protein MraZ compare
PfGW456L13_4781 -1.2 -1.2 Nudix hydrolase family protein PA3470 compare
PfGW456L13_3723 -1.2 -2.9 hypothetical protein compare
PfGW456L13_3333 -1.2 -1.4 hypothetical protein compare
PfGW456L13_818 -1.2 -1.8 Xanthine phosphoribosyltransferase (EC 2.4.2.22) compare
PfGW456L13_1078 -1.2 -2.9 ATP-dependent 23S rRNA helicase DbpA compare
PfGW456L13_360 -1.2 -1.8 FIG00956267: hypothetical protein compare
PfGW456L13_3291 -1.2 -1.5 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
PfGW456L13_1735 -1.2 -0.8 Glycerol uptake facilitator protein compare
PfGW456L13_2352 -1.1 -1.9 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) compare
PfGW456L13_4236 -1.1 -1.7 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) compare
PfGW456L13_1842 -1.1 -4.2 Outer membrane porin, OprD family compare
PfGW456L13_4661 -1.1 -2.5 Diacylglycerol kinase (EC 2.7.1.107) compare
PfGW456L13_4477 -1.1 -2.1 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_4992 -1.1 -6.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
PfGW456L13_1889 -1.1 -1.1 Phosphogluconate dehydratase (EC 4.2.1.12) compare
PfGW456L13_3047 -1.1 -1.5 Response regulator compare
PfGW456L13_3179 -1.1 -1.3 Organic hydroperoxide resistance transcriptional regulator compare
PfGW456L13_656 -1.1 -1.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
PfGW456L13_744 -1.1 -1.4 hypothetical protein compare
PfGW456L13_4013 -1.1 -2.2 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
PfGW456L13_3544 -1.1 -3.9 Branched-chain amino acid aminotransferase (EC 2.6.1.42) compare
PfGW456L13_1219 -1.1 -2.3 hypothetical protein compare
PfGW456L13_4514 -1.1 -3.2 Sigma factor RpoE negative regulatory protein RseB precursor compare
PfGW456L13_1768 -1.1 -3.6 two-component system sensor protein compare
PfGW456L13_403 -1.1 -2.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
PfGW456L13_556 -1.1 -2.2 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
PfGW456L13_581 -1.1 -1.4 hypothetical protein compare
PfGW456L13_3194 -1.1 -2.0 hypothetical protein compare
PfGW456L13_4419 -1.1 -1.0 Permeases of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_674 -1.1 -2.7 Chromosome (plasmid) partitioning protein ParB compare
PfGW456L13_275 -1.0 -0.7 3-dehydroquinate synthase (EC 4.2.3.4) compare
PfGW456L13_1139 -1.0 -5.0 Malate synthase G (EC 2.3.3.9) compare
PfGW456L13_150 -1.0 -0.8 hypothetical protein compare
PfGW456L13_1363 -1.0 -2.6 Rare lipoprotein A precursor compare
PfGW456L13_2931 -1.0 -1.3 transcriptional regulator MvaT, P16 subunit, putative compare
PfGW456L13_390 -1.0 -1.2 4-oxalocrotonate tautomerase (EC 5.3.2.-) compare
PfGW456L13_3159 -1.0 -2.6 FIG00960959: hypothetical protein compare
PfGW456L13_2117 -1.0 -1.9 transcriptional regulator compare
PfGW456L13_332 -1.0 -1.2 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
PfGW456L13_3190 -1.0 -2.4 Gfa-like protein compare
PfGW456L13_1854 -1.0 -1.5 4-hydroxybenzoyl-CoA thioesterase family active site compare
PfGW456L13_2470 -1.0 -2.9 Uncharacterized GST-like protein yncG compare
PfGW456L13_3955 -1.0 -2.2 Transcriptional regulator, TetR family compare
PfGW456L13_4980 -1.0 -1.6 FIG00953380: hypothetical protein compare
PfGW456L13_1813 -1.0 -3.8 Pyruvate kinase (EC 2.7.1.40) compare
PfGW456L13_2631 -1.0 -0.9 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) / NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) compare
PfGW456L13_1288 -1.0 -2.3 Isochorismatase (EC 3.3.2.1) compare
PfGW456L13_4042 -1.0 -1.6 FIG00953628: hypothetical protein compare
PfGW456L13_838 -1.0 -5.0 Ammonium transporter compare
PfGW456L13_4993 -1.0 -5.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
PfGW456L13_1011 -1.0 -1.2 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
PfGW456L13_1192 -1.0 -1.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
PfGW456L13_1850 -1.0 -3.2 FIG000859: hypothetical protein YebC compare
PfGW456L13_668 -1.0 -1.1 Ribonuclease P protein component (EC 3.1.26.5) compare
PfGW456L13_295 -1.0 -2.4 Transcriptional regulator PhaD compare
PfGW456L13_5059 -1.0 -1.1 hypothetical protein compare
PfGW456L13_5046 -1.0 -3.5 Predicted D-glucarate or D-galactorate regulator, GntR family compare
PfGW456L13_2551 -1.0 -1.6 Cell division trigger factor (EC 5.2.1.8) compare
PfGW456L13_1537 -1.0 -1.7 Hypothetical protein YqcC (clustered with tRNA pseudouridine synthase C) compare
PfGW456L13_4433 -1.0 -1.0 FIG00955751: hypothetical protein compare
PfGW456L13_2511 -1.0 -1.4 short-chain dehydrogenase/reductase SDR compare
PfGW456L13_844 -1.0 -1.2 Diaminopimelate epimerase (EC 5.1.1.7) compare
PfGW456L13_430 -0.9 -2.6 Glutamate--cysteine ligase (EC 6.3.2.2) compare
PfGW456L13_2523 -0.9 -1.6 Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-) compare
PfGW456L13_5113 -0.9 -5.9 Lactate-responsive regulator LldR in Enterobacteria, GntR family compare
PfGW456L13_4145 -0.9 -3.7 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
PfGW456L13_5003 -0.9 -1.1 YrbA protein compare
PfGW456L13_1896 -0.9 -4.0 ABC transporter for D-Galactose and D-Glucose, permease component 2 (from data) compare
PfGW456L13_4033 -0.9 -0.9 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
PfGW456L13_579 -0.9 -3.4 hypothetical protein compare
PfGW456L13_4946 -0.9 -1.6 hypothetical protein compare
PfGW456L13_1284 -0.9 -1.2 Putative transport protein compare
PfGW456L13_4179 -0.9 -2.3 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare


Specific Phenotypes

For 8 genes in this experiment

For nitrogen source Gly-DL-Asp in Pseudomonas fluorescens GW456-L13

For nitrogen source Gly-DL-Asp across organisms